NO20072939L - Makroloner - aminosubstituerte kinoloner - Google Patents

Makroloner - aminosubstituerte kinoloner

Info

Publication number
NO20072939L
NO20072939L NO20072939A NO20072939A NO20072939L NO 20072939 L NO20072939 L NO 20072939L NO 20072939 A NO20072939 A NO 20072939A NO 20072939 A NO20072939 A NO 20072939A NO 20072939 L NO20072939 L NO 20072939L
Authority
NO
Norway
Prior art keywords
macrolones
amino
substituted quinolones
quinolones
substituted
Prior art date
Application number
NO20072939A
Other languages
English (en)
Norwegian (no)
Inventor
Desmond John Best
John Stephen Elder
Andrea Fajdetic
Andrew Keith Forrest
Robert John Sheppard
Original Assignee
Glaxosmithkline Zagreb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Zagreb filed Critical Glaxosmithkline Zagreb
Publication of NO20072939L publication Critical patent/NO20072939L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO20072939A 2004-11-11 2007-06-08 Makroloner - aminosubstituerte kinoloner NO20072939L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0424959A GB0424959D0 (en) 2004-11-11 2004-11-11 Novel compounds
PCT/EP2005/012038 WO2006050942A1 (en) 2004-11-11 2005-11-09 Macrolones - amino substituted quinolones

Publications (1)

Publication Number Publication Date
NO20072939L true NO20072939L (no) 2007-08-08

Family

ID=33523587

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20072939A NO20072939L (no) 2004-11-11 2007-06-08 Makroloner - aminosubstituerte kinoloner

Country Status (19)

Country Link
US (2) US7718621B2 (pt)
EP (1) EP1824870A1 (pt)
JP (1) JP2008519788A (pt)
KR (1) KR20070085919A (pt)
CN (1) CN101098881A (pt)
AR (1) AR053311A1 (pt)
AU (1) AU2005303961A1 (pt)
BR (1) BRPI0517792A (pt)
CA (1) CA2587413A1 (pt)
GB (1) GB0424959D0 (pt)
IL (1) IL182978A0 (pt)
MA (1) MA29213B1 (pt)
MX (1) MX2007005776A (pt)
NO (1) NO20072939L (pt)
PE (1) PE20061137A1 (pt)
RU (1) RU2007121581A (pt)
TW (1) TW200630378A (pt)
WO (1) WO2006050942A1 (pt)
ZA (1) ZA200703603B (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7601695B2 (en) 2003-03-10 2009-10-13 Optimer Pharmaceuticals, Inc. Antibacterial agents
WO2007054295A1 (en) * 2005-11-09 2007-05-18 Glaxo Group Limited New 4*-substituted erythromycin derivative
EP1879904A1 (en) * 2005-05-10 2008-01-23 GlaxoSmithKline istrazivacki centar Zagreb d.o.o. 4" amino linked macrolides useful for the treatment of microbial infections
WO2007054296A1 (en) * 2005-11-09 2007-05-18 Glaxo Group Limited Macrolones
NZ583878A (en) 2007-09-14 2012-10-26 Vertex Pharma Modulators of ABC transporter and cystic fibrosis transmembrane conductance regulator (CFTR)
AU2008316830B2 (en) 2007-10-25 2016-03-17 Cempra Pharmaceuticals, Inc. Process for the preparation of macrolide antibacterial agents
TW200946109A (en) * 2008-05-09 2009-11-16 Enanta Pharm Inc Anti-bacterial activity of 9-hydroxy derivatives 6, 11-bicyclolides
CN107854477A (zh) 2008-10-24 2018-03-30 森普拉制药公司 使用含三唑的大环内酯治疗抗性疾病的方法
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
US9480679B2 (en) 2009-09-10 2016-11-01 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and MAC diseases
BR112012029586A2 (pt) * 2010-05-20 2016-08-02 Cempra Pharmaceuticals Inc processos para preparar macrolídeos e cetolídeos e intermediários dos mesmos
KR20130120458A (ko) 2010-09-10 2013-11-04 셈프라 파마슈티컬스, 인크. 질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드
WO2013148891A1 (en) 2012-03-27 2013-10-03 Cempra Pharmaceuticals, Inc. Parenteral formulations for administering macrolide antibiotics
WO2014152326A1 (en) 2013-03-14 2014-09-25 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
AU2014233240B2 (en) 2013-03-15 2018-08-09 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents
CN106589023A (zh) * 2016-11-22 2017-04-26 宜昌东阳光药业股份有限公司 一种罗红霉素杂质及其合成方法
CN110475777B (zh) 2017-03-30 2022-04-15 豪夫迈·罗氏有限公司 用于治疗和预防细菌感染的新吡啶并[2,3-b]吲哚化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2808070A1 (de) * 1978-02-24 1979-08-30 Bayer Ag Verfahren zur herstellung von 4-pyridon-3-carbonsaeuren und/oder deren derivaten
GB0127349D0 (en) 2001-11-14 2002-01-02 Glaxo Group Ltd Macrolides
GB0225384D0 (en) 2002-10-31 2002-12-11 Glaxo Group Ltd Novel compounds

Also Published As

Publication number Publication date
US20080090773A1 (en) 2008-04-17
MX2007005776A (es) 2007-07-16
PE20061137A1 (es) 2006-12-13
AR053311A1 (es) 2007-05-02
TW200630378A (en) 2006-09-01
EP1824870A1 (en) 2007-08-29
US20080269146A1 (en) 2008-10-30
MA29213B1 (fr) 2008-02-01
KR20070085919A (ko) 2007-08-27
RU2007121581A (ru) 2008-12-20
US7718621B2 (en) 2010-05-18
CN101098881A (zh) 2008-01-02
GB0424959D0 (en) 2004-12-15
AU2005303961A1 (en) 2006-05-18
JP2008519788A (ja) 2008-06-12
IL182978A0 (en) 2007-08-19
CA2587413A1 (en) 2006-05-18
WO2006050942A1 (en) 2006-05-18
ZA200703603B (en) 2008-07-30
BRPI0517792A (pt) 2008-10-21

Similar Documents

Publication Publication Date Title
NO20074703L (no) Antibakterielle piperidinderivater
NO20081729L (no) Nye diazaspiroalkaner og deres anvendelse for behandling av CCR8-medierte sykdommer
NO20071504L (no) Pyrimidinderivanter.
NO20090628L (no) Pyridizinon derivativater
NO20081844L (no) Terapeutiske forbindelser
NO20076648L (no) Novel thiophene derivatives
NO20092476L (no) Antibakterielle polycykliske ureaforbindelser
NO20091553L (no) Fenylderivater og deres anvendelse som immunmodulatorer
NO20083434L (no) Benzamid- og heteroarenderivater
NO20070224L (no) 2-karbamid-4-fenyltiazolderivater, fremstilling og terapeutisk anvendelse derav
NO20072978L (no) Nye betuinderivater, preparat derav og anvendelse derav
NO20076675L (no) Aminopiperidinquinoliner og deres azaisosteriske analoger med antibakteriell aktivitet
NO20080675L (no) P38-Map kinaseinhibitorer og metoder for deres anvendelse
NO20071593L (no) Pyrimidinderivater
NO20091893L (no) Nye 1,4-benzotiepin-1,1-dioksidderivater som er substituert med benzylgrupper, fremgangsmater for fremstilling av medisiner inneholdende forbindelsene og anvendelse derav.
NO20084129L (no) Pyridin(3,4-B)Pyrazinoner
NO20091409L (no) Pyridin-3-yl-derivater som immunmodulerende midler
NO20071776L (no) Kinoksaliner som B RAF inhibitorer.
NO20065946L (no) DPP-IV-inhibitorer
MY151455A (en) Carbonylamino pyrrolopyrazoles, potent kinase inhibitors
NO20082793L (no) Nye tiofenderivater
NO20032926D0 (no) Heterocykliske forbindelser som har antibakteriell aktivitet, fremgangsmåtefor deres fremstilling og farmasöytiske sammensetningerinneholdende dem
NO20054329L (no) Adamantanderivater, fremgangsmater for deres fremstilling og farmasoytiske sammensetninger som innbefatter slike
MX2009008541A (es) Fenilcarbamatos macrociclicos que inhiben el virus de hepatitis c.
NO20090346L (no) Pyrazolderivater som inhibitorer av cytokrom P450

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application