NO20072965L - Potentiatorer av glutamatreceptorer - Google Patents

Potentiatorer av glutamatreceptorer

Info

Publication number: NO20072965L
Authority: NO; Norway
Prior art keywords: potentiators; glutamate receptors; same; intermediates; preparing
Prior art date: 2004-11-22

Application number

NO20072965A

Other languages

English (en)

Norwegian (no)

Inventor

Thomas Daniel Aicher

Guillermo S Cortez

Todd Michael Groendyke

Albert Khilevich

James Allen Knobelsdorf

Nicholas Andrew Magnus

Fredrik Pehr Marmsater

Jeffrey Michael Schkeryantz

Tony Pisal Tang

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-11-22

Filing date

2007-06-11

Publication date

2007-06-28

2007-06-11 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

2007-06-28 Publication of NO20072965L publication Critical patent/NO20072965L/no

Links

102000018899 Glutamate Receptors Human genes 0.000 title 1
108010027915 Glutamate Receptors Proteins 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C229/60—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring with amino and carboxyl groups bound in meta- or para- positions
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A—HUMAN NECESSITIES
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- C—CHEMISTRY; METALLURGY
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
- C—CHEMISTRY; METALLURGY
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
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- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
- C—CHEMISTRY; METALLURGY
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- C07D213/62—Oxygen or sulfur atoms
- C07D213/70—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
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- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C—CHEMISTRY; METALLURGY
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C—CHEMISTRY; METALLURGY
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- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
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Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Immunology (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Epidemiology (AREA)
Anesthesiology (AREA)
Heart & Thoracic Surgery (AREA)
Ophthalmology & Optometry (AREA)
Addiction (AREA)
Otolaryngology (AREA)
Cardiology (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pyridine Compounds (AREA)
Saccharide Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)

NO20072965A 2004-11-22 2007-06-11 Potentiatorer av glutamatreceptorer NO20072965L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US63006004P	2004-11-22	2004-11-22
PCT/US2005/041441 WO2006057870A1 (fr)	2004-11-22	2005-11-15	Potentialisateurs de recepteurs du glutamate

Publications (1)

Publication Number	Publication Date
NO20072965L true NO20072965L (no)	2007-06-28

Family

ID=35929650

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
NO20072965A NO20072965L (no)	2004-11-22	2007-06-11	Potentiatorer av glutamatreceptorer
NO20072971A NO20072971L (no)	2004-11-22	2007-06-11	Potentiatorer av glutamatreceptorer

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
NO20072971A NO20072971L (no)	2004-11-22	2007-06-11	Potentiatorer av glutamatreceptorer

Country Status (28)

Country	Link
US (5)	US7678794B2 (fr)
EP (4)	EP1817300B1 (fr)
JP (2)	JP5184089B2 (fr)
KR (3)	KR100895167B1 (fr)
CN (3)	CN101061106B (fr)
AT (3)	ATE543807T1 (fr)
AU (2)	AU2005309855B2 (fr)
BR (2)	BRPI0518360A2 (fr)
CA (2)	CA2588881C (fr)
CY (2)	CY1109998T1 (fr)
DE (2)	DE602005017510D1 (fr)
DK (2)	DK1817300T3 (fr)
EA (2)	EA200701122A1 (fr)
ES (3)	ES2340600T3 (fr)
HR (1)	HRP20120137T1 (fr)
IL (2)	IL182959A0 (fr)
MA (2)	MA29135B1 (fr)
MX (2)	MX2007006145A (fr)
NO (2)	NO20072965L (fr)
NZ (1)	NZ554399A (fr)
PL (2)	PL1817300T3 (fr)
PT (2)	PT1817300E (fr)
RS (1)	RS52268B (fr)
SI (2)	SI1817301T1 (fr)
TN (2)	TNSN07196A1 (fr)
UA (1)	UA90695C2 (fr)
WO (3)	WO2006057860A1 (fr)
ZA (2)	ZA200703579B (fr)

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MY153913A (en)	2009-05-12	2015-04-15	Janssen Pharmaceuticals Inc	7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
WO2011116356A2 (fr) *	2010-03-19	2011-09-22	Sanford-Burnham Medical Research Institute	Modulateurs allostériques positifs de mglurs de type 2
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EP2746260A1 (fr)	2012-12-21	2014-06-25	Basf Se	Composés de [1,2,4]triazole et d'imidazole substitués
JO3368B1 (ar)	2013-06-04	2019-03-13	Janssen Pharmaceutica Nv	مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2
JO3367B1 (ar)	2013-09-06	2019-03-13	Janssen Pharmaceutica Nv	مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
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PL3096790T3 (pl)	2014-01-21	2020-01-31	Janssen Pharmaceutica, N.V.	Kombinacje zawierające pozytywne modulatory allosteryczne lub agonistów ortosterycznych metabotropowego receptora glutaminergicznego podtypu 2 i ich zastosowanie
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Publication number	Publication date
DK1817300T3 (da)	2010-05-17
MX2007006145A (es)	2007-10-23
KR20070064375A (ko)	2007-06-20
PL1817300T3 (pl)	2010-08-31
US7678794B2 (en)	2010-03-16
JP5184089B2 (ja)	2013-04-17
CN101061106B (zh)	2010-09-29
EP1817300A1 (fr)	2007-08-15
US20080139505A1 (en)	2008-06-12
IL182957A (en)	2012-08-30
CA2590349A1 (fr)	2006-06-01
CA2588881C (fr)	2013-04-09
PL1817301T3 (pl)	2012-08-31
AU2005309855B2 (en)	2011-10-06
EP1817300B1 (fr)	2010-03-17
EP2441762A1 (fr)	2012-04-18
EA011867B1 (ru)	2009-06-30
ZA200704001B (en)	2008-10-29
CN101955470B (zh)	2012-06-13
CY1112402T1 (el)	2015-12-09
TNSN07195A1 (en)	2008-11-21
NO20072971L (no)	2007-06-27
WO2006057860A1 (fr)	2006-06-01
AU2005309855A1 (en)	2006-06-01
SI1817301T1 (sl)	2012-04-30
US7816523B2 (en)	2010-10-19
RS52268B (sr)	2012-10-31
EP1817301B1 (fr)	2012-02-01
US20080096930A1 (en)	2008-04-24
EP1817301A1 (fr)	2007-08-15
KR100895167B1 (ko)	2009-05-04
ES2333979T3 (es)	2010-03-03
MA29136B1 (fr)	2008-01-02
UA90695C2 (en)	2010-05-25
CN101955470A (zh)	2011-01-26
CN101061106A (zh)	2007-10-24
IL182959A0 (en)	2007-08-19
MX2007006146A (es)	2007-08-07
AU2005309865A1 (en)	2006-06-01
IL182957A0 (en)	2007-08-19
DE602005020056D1 (de)	2010-04-29
TNSN07196A1 (en)	2008-11-21
KR20090006237A (ko)	2009-01-14
ATE461188T1 (de)	2010-04-15
PT1817300E (pt)	2010-05-28
HK1109140A1 (en)	2008-05-30
EP1817296A1 (fr)	2007-08-15
NZ554399A (en)	2010-10-29
MA29135B1 (fr)	2008-01-02
CA2590349C (fr)	2013-05-07
US20090318483A1 (en)	2009-12-24
CA2588881A1 (fr)	2006-06-01
PT1817301E (pt)	2012-04-03
ES2340600T3 (es)	2010-06-07
JP2008520680A (ja)	2008-06-19
EA200701122A1 (ru)	2007-12-28
ES2378673T3 (es)	2012-04-16
JP5175551B2 (ja)	2013-04-03
WO2006057870A1 (fr)	2006-06-01
ZA200703579B (en)	2009-04-29
WO2006057869A1 (fr)	2006-06-01
US7858646B2 (en)	2010-12-28
US20080004321A1 (en)	2008-01-03
CN101061105B (zh)	2012-05-30
EA200701121A1 (ru)	2007-12-28
KR20070085412A (ko)	2007-08-27
US7598423B2 (en)	2009-10-06
ATE543807T1 (de)	2012-02-15
AU2005309865B2 (en)	2011-07-28
DE602005017510D1 (de)	2009-12-17
US20090318481A1 (en)	2009-12-24
ATE447562T1 (de)	2009-11-15
DK1817301T3 (da)	2012-02-27
BRPI0518459A2 (pt)	2008-11-18
CY1109998T1 (el)	2014-09-10
BRPI0518360A2 (pt)	2008-11-18
CN101061105A (zh)	2007-10-24
HRP20120137T1 (hr)	2012-03-31
US7803938B2 (en)	2010-09-28
SI1817300T1 (sl)	2010-07-30
JP2008520676A (ja)	2008-06-19
EP1817296B1 (fr)	2009-11-04

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2015-06-22	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO20072971L (no)	2007-06-27	Potentiatorer av glutamatreceptorer
ATE548374T1 (de)	2012-03-15	2'-fluor-2'-desoxytetrahydrouridine als cytidindeaminaseinhibitoren
EA200500203A1 (ru)	2005-08-25	Новый способ синтеза и новая кристаллическая форма агомелатина и фармацевтические композиции, которые её содержат
SE0301373D0 (sv)	2003-05-09	Novel compounds
ATE473744T1 (de)	2010-07-15	Modifizierte pyrimidin-glucocorticoid-rezeptor- modulatoren
WO2004092135A3 (fr)	2005-08-04	Composes therapeutiques
WO2006034093A3 (fr)	2006-07-13	Inhibiteurs de bace
NO20091052L (no)	2009-04-06	Diaryleterderivater og anvendelser derav
EA200700982A1 (ru)	2007-10-26	Производные хинолина и изохинолина, замещённые в 5-ом положении, способ их получения и их применение в качестве противовоспалительных средств
WO2007079163A3 (fr)	2007-08-30	Antagonistes du recepteur de la prokineticine 1
HRP20080057T3 (en)	2008-02-29	9,10-alpha,alpha-oh-taxane analogs and methods for production thereof
MY153719A (en)	2015-03-13	Prokineticin 1 receptor antagonists
TW200745024A (en)	2007-12-16	Carboxamide derivatives as muscarinic receptor antagonists
EA200700766A1 (ru)	2007-10-26	Способ получения производных [1,4,5]-оксадиазепина
EA200800070A1 (ru)	2008-04-28	Производные 2-(1h-индолилсульфанил)ариламина
MY140858A (en)	2010-01-29	Ampa receptor potentiators
WO2006078887A3 (fr)	2007-03-01	Derives de methylphenidate et leurs utilisations
EA200702618A1 (ru)	2008-04-28	Активаторы рецептора ampa
MX2007007554A (es)	2007-07-20	Oxiarenos sustituidos.
CR9104A (es)	2007-12-07	Potenciadores de receptores de glutamato