NO20073310L - Aminopyridiner som inhibitorer av beta-sekretase - Google Patents
Aminopyridiner som inhibitorer av beta-sekretaseInfo
- Publication number
- NO20073310L NO20073310L NO20073310A NO20073310A NO20073310L NO 20073310 L NO20073310 L NO 20073310L NO 20073310 A NO20073310 A NO 20073310A NO 20073310 A NO20073310 A NO 20073310A NO 20073310 L NO20073310 L NO 20073310L
- Authority
- NO
- Norway
- Prior art keywords
- secretase
- aminopyridines
- inhibitors
- beta
- present
- Prior art date
Links
- 108010043324 Amyloid Precursor Protein Secretases Proteins 0.000 title abstract 2
- 102000002659 Amyloid Precursor Protein Secretases Human genes 0.000 title abstract 2
- 150000003927 aminopyridines Chemical class 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 208000037259 Amyloid Plaque Diseases 0.000 abstract 1
- 102000013455 Amyloid beta-Peptides Human genes 0.000 abstract 1
- 108010090849 Amyloid beta-Peptides Proteins 0.000 abstract 1
- 102100021257 Beta-secretase 1 Human genes 0.000 abstract 1
- 101000894895 Homo sapiens Beta-secretase 1 Proteins 0.000 abstract 1
- -1 aminopyridine compound Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64906805P | 2005-02-01 | 2005-02-01 | |
| PCT/US2006/003186 WO2006083760A1 (en) | 2005-02-01 | 2006-01-26 | AMINO-PYRIDINES AS INHIBITORS OF β-SECRETASE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20073310L true NO20073310L (no) | 2007-09-26 |
Family
ID=36481239
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20073310A NO20073310L (no) | 2005-02-01 | 2007-06-28 | Aminopyridiner som inhibitorer av beta-sekretase |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US7732457B2 (pt) |
| EP (1) | EP1844035A1 (pt) |
| JP (1) | JP2008528622A (pt) |
| KR (1) | KR20070107062A (pt) |
| CN (1) | CN101111489A (pt) |
| AR (1) | AR053120A1 (pt) |
| AU (1) | AU2006211159A1 (pt) |
| BR (1) | BRPI0607094A2 (pt) |
| CA (1) | CA2593857A1 (pt) |
| CR (1) | CR9272A (pt) |
| GT (1) | GT200600035A (pt) |
| IL (1) | IL184303A0 (pt) |
| MX (1) | MX2007009313A (pt) |
| NO (1) | NO20073310L (pt) |
| RU (1) | RU2007124935A (pt) |
| SV (1) | SV2007002397A (pt) |
| TW (1) | TW200639166A (pt) |
| WO (1) | WO2006083760A1 (pt) |
| ZA (1) | ZA200706345B (pt) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7763609B2 (en) | 2003-12-15 | 2010-07-27 | Schering Corporation | Heterocyclic aspartyl protease inhibitors |
| ATE423121T1 (de) | 2004-06-16 | 2009-03-15 | Wyeth Corp | Diphenylimidazopyrimidin- und -imidazolamine als b-sekretase-inhibitoren |
| ES2332659T3 (es) * | 2004-06-16 | 2010-02-10 | Wyeth | Derivados de amino-5,5-difenilimidazolona para la inhibicion de beta-secretasa. |
| JP2008523139A (ja) * | 2004-12-14 | 2008-07-03 | アストラゼネカ・アクチエボラーグ | 置換アミノピリジン類及びその使用 |
| CN101103034A (zh) * | 2005-01-14 | 2008-01-09 | 惠氏公司 | 抑制β-分泌酶的氨基-咪唑酮 |
| BRPI0606902A2 (pt) | 2005-02-14 | 2009-07-28 | Wyeth Corp | composto; método para o tratamento de uma doença ou distúrbio associado a atividade excessiva de bace em um paciente que dele necessite; método para modular a atividade de bace; composição farmacêutica |
| EP1896448A1 (en) * | 2005-06-30 | 2008-03-12 | Wyeth | AMINO-5-(6-MEMBERED)HETEROARYLIMIDAZOLONE COMPOUNDS AND THE USE THEREOF FOR ß-SECRETASE MODULATION |
| TW200738683A (en) * | 2005-06-30 | 2007-10-16 | Wyeth Corp | Amino-5-(5-membered)heteroarylimidazolone compounds and the use thereof for β-secretase modulation |
| TW200730523A (en) * | 2005-07-29 | 2007-08-16 | Wyeth Corp | Cycloalkyl amino-hydantoin compounds and use thereof for β-secretase modulation |
| KR20080050430A (ko) * | 2005-09-26 | 2008-06-05 | 와이어쓰 | 베타-세크레타제 (ｂａｃｅ) 억제제로서아미노-5-[4-(디플루오로메톡시)페닐]-5-페닐이미다졸론화합물 |
| CN101360737A (zh) * | 2005-12-19 | 2009-02-04 | 惠氏公司 | 2-氨基-5-哌啶咪唑酮化合物和其用于β分泌酶调节的用途 |
| WO2007100536A1 (en) * | 2006-02-24 | 2007-09-07 | Wyeth | DIHYDROSPIRO[DIBENZO[A,D][7]ANNULENE-5,4'-IMIDAZOL] COMPOUNDS FOR THE INHIBITION OF β-SECRETASE |
| US7700606B2 (en) * | 2006-08-17 | 2010-04-20 | Wyeth Llc | Imidazole amines as inhibitors of β-secretase |
| EP2064201A2 (en) * | 2006-09-21 | 2009-06-03 | Wyeth | Indolylalkylpyridin-2-amines for the inhibition of beta-secretase |
| BRPI0719379A2 (pt) * | 2006-11-24 | 2014-02-11 | Ac Immune Sa | Composto, composição farmacêutica, uso de composto, mistura, métodos para coletar dados para o diagnóstico de uma doença ou condição associada com amilóide em uma amostra ou um paciente, para determinar a extensão da carga de placa amiloidogênica em um tecido e/ou um fluido corporal, para coletar dados para determinar a predisposição a uma doença ou condição associada com amilóide em um paciente, para coletar dados para monitorar a doença residual mínima em um paciente seguindo o tratamento com um anticorpo ou uma composição de vacina e para coletar dados para predizer a responsividade de um paciente sendo tratado com um anticorpo ou uma composição de vacina, e, kit de teste |
| CL2008000784A1 (es) * | 2007-03-20 | 2008-05-30 | Wyeth Corp | Compuestos amino-5-[-4-(diflourometoxi) fenil sustituido]-5-fenilmidazolona, inhibidores de b-secretasa; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar alzheimer, deterioro cognitivo, sindrome de down, disminucion co |
| CL2008000791A1 (es) * | 2007-03-23 | 2008-05-30 | Wyeth Corp | Compuestos derivados de 2-amino-5-(4-difluorometoxi-fenil)-5-fenil-imidazolidin-4-ona; composicion farmaceutica que comprende a dichos compuestos; y su uso en el tratamiento de una enfermedad asociada con la actividad bace excesiva, tales como enferm |
| EA020031B1 (ru) * | 2009-06-11 | 2014-08-29 | Эббви Бахамаз Лтд. | Противовирусные соединения |
| US8937150B2 (en) | 2009-06-11 | 2015-01-20 | Abbvie Inc. | Anti-viral compounds |
| WO2011115938A1 (en) | 2010-03-15 | 2011-09-22 | Amgen Inc. | Spiro-tetracyclic ring compounds as beta - secretase modulators |
| AU2011227501B9 (en) | 2010-03-15 | 2013-08-22 | Amgen Inc. | Amino -dihydrooxazine and amino - dihydrothiazine spiro compounds as Beta - secretase modulators and their medical use |
| MX339192B (es) * | 2010-03-24 | 2016-05-13 | Amitech Therapeutic Solutions Inc | Compuestos heterociclicos utiles para inhibicion de cinasa. |
| NZ605440A (en) | 2010-06-10 | 2014-05-30 | Abbvie Bahamas Ltd | Solid compositions comprising an hcv inhibitor |
| WO2012019056A1 (en) | 2010-08-05 | 2012-02-09 | Amgen Inc. | Amino-iso-indole, amino-aza-iso-indole, amino-dihydroisoquinoline and amino-benzoxazine compounds as beta-secretase modulators and methods of use |
| ES2879314T3 (es) | 2010-08-18 | 2021-11-22 | Biosplice Therapeutics Inc | Dicetonas e hidroxicetonas como activadores de la vía de señalización de catenina |
| WO2012071279A1 (en) | 2010-11-23 | 2012-05-31 | Amgen Inc. | Spiro-amino-imidazolone and spiro-amino-dihydro-pyrimidinone compounds as beta-secretase modulators and methods of use |
| US9346827B2 (en) | 2011-02-07 | 2016-05-24 | Amgen Inc. | 5-amino-oxazepine and 5-amino-thiazepane compounds as beta secretase antagonists and methods of use |
| EP2675810A1 (en) | 2011-02-15 | 2013-12-25 | Amgen Inc. | Spiro-amino-imidazo-fused heterocyclic compounds as beta-secretase modulators and methods of use |
| US10201584B1 (en) | 2011-05-17 | 2019-02-12 | Abbvie Inc. | Compositions and methods for treating HCV |
| US9296759B2 (en) | 2011-09-21 | 2016-03-29 | Amgen Inc. | Amino-oxazine and amino-dihydrothiazine compounds as beta-secretase modulators and methods of use |
| US9034832B2 (en) | 2011-12-29 | 2015-05-19 | Abbvie Inc. | Solid compositions |
| WO2014078314A1 (en) | 2012-11-15 | 2014-05-22 | Amgen Inc. | Amino-oxazine and amino-dihydrothiazine compounds as beta-secretase modulators and methods of use |
| PL2968249T3 (pl) | 2013-02-22 | 2019-06-28 | Samumed, Llc | Gamma-diketony jako aktywatory szlaku sygnałowego Wnt/beta-kateniny |
| US11484534B2 (en) | 2013-03-14 | 2022-11-01 | Abbvie Inc. | Methods for treating HCV |
| WO2015103490A1 (en) | 2014-01-03 | 2015-07-09 | Abbvie, Inc. | Solid antiviral dosage forms |
| US9795550B2 (en) | 2014-08-20 | 2017-10-24 | Samumed, Llc | Gamma-diketones for treatment and prevention of aging skin and wrinkles |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE45198B1 (en) | 1976-06-05 | 1982-07-14 | Wyeth John & Brother Ltd | Guanidine derivatives |
| DE2901362A1 (de) | 1978-01-25 | 1979-07-26 | Sandoz Ag | Guanidinderivate, ihre herstellung und verwendung |
| GB1588096A (en) | 1978-05-20 | 1981-04-15 | Wyeth & Bros Ltd John | Pyrrole derivatives |
| GB9511694D0 (en) | 1995-06-09 | 1995-08-02 | Fujisawa Pharmaceutical Co | Benzamide derivatives |
| ZA967800B (en) | 1995-09-20 | 1997-04-03 | Yamanouchi Pharma Co Ltd | Heteroaryllsubstituted acryloylguanidine derivatives and pharmaceutical compositions comprising them |
| GB9611046D0 (en) | 1996-05-25 | 1996-07-31 | Wivenhoe Techn Ltd | Pharmacological compounds |
| GB2323841A (en) | 1997-04-04 | 1998-10-07 | Ferring Bv Group Holdings | Pyridine derivatives with anti-tumor and anti-inflammatory activity |
| TW544448B (en) | 1997-07-11 | 2003-08-01 | Novartis Ag | Pyridine derivatives |
| US6492408B1 (en) | 1999-07-21 | 2002-12-10 | Boehringer Ingelheim Pharmaceuticals, Inc. | Small molecules useful in the treatment of inflammatory disease |
| DE10024319A1 (de) | 2000-05-17 | 2001-11-22 | Merck Patent Gmbh | Bisacylguanidine |
| DE10046993A1 (de) | 2000-09-22 | 2002-04-11 | Aventis Pharma Gmbh | Substituierte Zimtsäureguanidide, Verfahren zur ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltendes Medikament |
| AU2002352189A1 (en) * | 2001-11-30 | 2003-06-10 | Smithkline Beecham P.L.C. | Hydroxyethylene compounds with asp2 inhibitory activity |
| AU2002347022A1 (en) | 2001-12-20 | 2003-07-09 | Novo Nordisk A/S | Benzimidazols and indols as glucagon receptor antagonists/inverse agonisten |
| WO2003064396A1 (en) | 2002-02-01 | 2003-08-07 | Elan Pharmaceuticals, Inc. | Hydroxyalkanoyl aminopyrazoles and related compounds |
| US6974829B2 (en) | 2002-05-07 | 2005-12-13 | Elan Pharmaceuticals, Inc. | Succinoyl aminopyrazoles and related compounds |
| WO2004058727A1 (en) | 2002-12-20 | 2004-07-15 | Bayer Pharmaceuticals Corporation | Substituted 3,5-dihydro-4h-imidazol-4-ones for the treatment of obesity |
| GB0308318D0 (en) * | 2003-04-10 | 2003-05-14 | Merck Sharp & Dohme | Therapeutic agents |
| MXPA05011150A (es) * | 2003-04-21 | 2005-12-14 | Elan Pharm Inc | 2-hidroxi-3-diaminoalcanos de benzamida. |
| WO2005005412A1 (en) | 2003-07-01 | 2005-01-20 | Bayer Cropscience Gmbh | 3-pyridylcarboxamide derivatives as pesticidal agents |
| US7592348B2 (en) | 2003-12-15 | 2009-09-22 | Schering Corporation | Heterocyclic aspartyl protease inhibitors |
| EP2335701B1 (en) | 2003-12-15 | 2012-07-11 | Schering Corporation | Heterocyclic aspartyl protease inhibitors |
| US7700603B2 (en) | 2003-12-15 | 2010-04-20 | Schering Corporation | Heterocyclic aspartyl protease inhibitors |
| ES2332659T3 (es) | 2004-06-16 | 2010-02-10 | Wyeth | Derivados de amino-5,5-difenilimidazolona para la inhibicion de beta-secretasa. |
| ATE423121T1 (de) | 2004-06-16 | 2009-03-15 | Wyeth Corp | Diphenylimidazopyrimidin- und -imidazolamine als b-sekretase-inhibitoren |
| CN101103034A (zh) | 2005-01-14 | 2008-01-09 | 惠氏公司 | 抑制β-分泌酶的氨基-咪唑酮 |
| WO2006088694A1 (en) | 2005-02-14 | 2006-08-24 | Wyeth | SUBSTITUTED THIENYL AND FURYL ACYLGUANIDINES AS β-SECRETASE MODULATORS |
| BRPI0606902A2 (pt) | 2005-02-14 | 2009-07-28 | Wyeth Corp | composto; método para o tratamento de uma doença ou distúrbio associado a atividade excessiva de bace em um paciente que dele necessite; método para modular a atividade de bace; composição farmacêutica |
| WO2006088705A1 (en) | 2005-02-14 | 2006-08-24 | Wyeth | Terphenyl guanidines as [beta symbol] -secretase inhibitors |
| EP1896448A1 (en) | 2005-06-30 | 2008-03-12 | Wyeth | AMINO-5-(6-MEMBERED)HETEROARYLIMIDAZOLONE COMPOUNDS AND THE USE THEREOF FOR ß-SECRETASE MODULATION |
| TW200738683A (en) | 2005-06-30 | 2007-10-16 | Wyeth Corp | Amino-5-(5-membered)heteroarylimidazolone compounds and the use thereof for β-secretase modulation |
| TW200730523A (en) | 2005-07-29 | 2007-08-16 | Wyeth Corp | Cycloalkyl amino-hydantoin compounds and use thereof for β-secretase modulation |
| KR20080050430A (ko) | 2005-09-26 | 2008-06-05 | 와이어쓰 | 베타-세크레타제 (ｂａｃｅ) 억제제로서아미노-5-[4-(디플루오로메톡시)페닐]-5-페닐이미다졸론화합물 |
| CN101360737A (zh) | 2005-12-19 | 2009-02-04 | 惠氏公司 | 2-氨基-5-哌啶咪唑酮化合物和其用于β分泌酶调节的用途 |
| WO2007100536A1 (en) | 2006-02-24 | 2007-09-07 | Wyeth | DIHYDROSPIRO[DIBENZO[A,D][7]ANNULENE-5,4'-IMIDAZOL] COMPOUNDS FOR THE INHIBITION OF β-SECRETASE |
| US7700606B2 (en) | 2006-08-17 | 2010-04-20 | Wyeth Llc | Imidazole amines as inhibitors of β-secretase |
-
2006
- 2006-01-26 MX MX2007009313A patent/MX2007009313A/es unknown
- 2006-01-26 KR KR1020077019308A patent/KR20070107062A/ko not_active Withdrawn
- 2006-01-26 EP EP06719856A patent/EP1844035A1/en not_active Withdrawn
- 2006-01-26 WO PCT/US2006/003186 patent/WO2006083760A1/en not_active Ceased
- 2006-01-26 BR BRPI0607094-9A patent/BRPI0607094A2/pt not_active IP Right Cessation
- 2006-01-26 CA CA002593857A patent/CA2593857A1/en not_active Abandoned
- 2006-01-26 JP JP2007553315A patent/JP2008528622A/ja not_active Withdrawn
- 2006-01-26 CN CNA2006800036609A patent/CN101111489A/zh active Pending
- 2006-01-26 AU AU2006211159A patent/AU2006211159A1/en not_active Abandoned
- 2006-01-26 RU RU2007124935/04A patent/RU2007124935A/ru not_active Application Discontinuation
- 2006-01-27 TW TW095103606A patent/TW200639166A/zh unknown
- 2006-01-31 GT GT200600035A patent/GT200600035A/es unknown
- 2006-01-31 AR ARP060100342A patent/AR053120A1/es unknown
- 2006-01-31 US US11/344,432 patent/US7732457B2/en not_active Expired - Fee Related
- 2006-02-01 SV SV2006002397A patent/SV2007002397A/es not_active Application Discontinuation
-
2007
- 2007-06-28 IL IL184303A patent/IL184303A0/en unknown
- 2007-06-28 NO NO20073310A patent/NO20073310L/no not_active Application Discontinuation
- 2007-07-23 CR CR9272A patent/CR9272A/es not_active Application Discontinuation
- 2007-07-31 ZA ZA200706345A patent/ZA200706345B/xx unknown
-
2010
- 2010-04-20 US US12/763,612 patent/US20100204245A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| MX2007009313A (es) | 2007-09-12 |
| WO2006083760A1 (en) | 2006-08-10 |
| BRPI0607094A2 (pt) | 2009-08-04 |
| JP2008528622A (ja) | 2008-07-31 |
| CN101111489A (zh) | 2008-01-23 |
| RU2007124935A (ru) | 2009-03-10 |
| AU2006211159A1 (en) | 2006-08-10 |
| CR9272A (es) | 2007-10-03 |
| US20060173049A1 (en) | 2006-08-03 |
| US20100204245A1 (en) | 2010-08-12 |
| US7732457B2 (en) | 2010-06-08 |
| AR053120A1 (es) | 2007-04-25 |
| KR20070107062A (ko) | 2007-11-06 |
| IL184303A0 (en) | 2007-10-31 |
| TW200639166A (en) | 2006-11-16 |
| SV2007002397A (es) | 2007-02-16 |
| ZA200706345B (en) | 2009-08-26 |
| GT200600035A (es) | 2006-09-11 |
| CA2593857A1 (en) | 2006-08-10 |
| EP1844035A1 (en) | 2007-10-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO20074148L (no) | Azolylacylguanidiner som beta-sekretase inhibitorer | |
| TW200639166A (en) | Amino-pyridines as inhibitors of β-secretase | |
| NO20073099L (no) | Amino-imidazoloner for inhibering av beta-sekretase | |
| NO20080942L (no) | Amino-5-[4-(difluormetoksy)-fenyl]-5-fenylimidazolonforbindelser som inhibitorer av beta-sekretase (BACE) | |
| NO20074666L (no) | Imidazo(1,2-A)pyridinforbindelser som VEGF-R2-inhibitorer | |
| TW200730523A (en) | Cycloalkyl amino-hydantoin compounds and use thereof for β-secretase modulation | |
| TW200738683A (en) | Amino-5-(5-membered)heteroarylimidazolone compounds and the use thereof for β-secretase modulation | |
| WO2007078813A8 (en) | 2-AMINO-5-PIPERIDINYLIMIDAZOLONE COMPOUNDS AND USE THEREOF FOR β-SECRETASE MODULATION | |
| NO20080150L (no) | Inhibitorer av AKT-aktivitet | |
| WO2008118379A3 (en) | AMINO-5-[4-(DIFLUOROMETHOXY)PHENYL]-5-PHENYLIMIDAZOLONE COMPOUNDS FOR THE INHIBITION OF β-SECRETASE | |
| NO20083220L (no) | Heterocykliske derivater som modulatorer for ionekanaler | |
| NO20083207L (no) | Inhibitorer av IAP | |
| NO20072918L (no) | Heteroaromatiske quinolinforbindelser, og anvendelse av disse som inhibitorer av PDE10 | |
| EA200970349A1 (ru) | Ингибиторы металлопротеазы гетероциклического происхождения | |
| EA200800865A1 (ru) | Биарилзамещенные гетероциклические ингибиторы lta4h для лечения воспаления | |
| EA201070423A1 (ru) | Диарильные соединения оксадиазолов | |
| NO20056192L (no) | Kapaseinhibitorer og anvendelse derav | |
| NO20073170L (no) | Kaspaseinhibitorer og anvendelse derav | |
| UA83875C2 (ru) | Производные хинолина для применения в качестве микобактериальных ингибиторов | |
| NO20063647L (no) | Nye inhibitorer av chymase | |
| EA201001348A1 (ru) | Пирролопиримидинкарбоксамиды | |
| NO20063944L (no) | Piperidinylkarbonyl-pyrrolidiner og deres anvendelse som melanokortinagonister | |
| NO20064351L (no) | Caspaseinhibitorer og anvendelser derav | |
| NO20060963L (no) | Nikotinamidderivater anvendelige som PDE4-inhibitorer | |
| WO2008036196A3 (en) | Indolylalkylpyridin-2-amines for the inhibition of beta-secretase |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |