NO20073849L - Indolderivater for behandling av virale infeksjoner - Google Patents
Indolderivater for behandling av virale infeksjonerInfo
- Publication number
- NO20073849L NO20073849L NO20073849A NO20073849A NO20073849L NO 20073849 L NO20073849 L NO 20073849L NO 20073849 A NO20073849 A NO 20073849A NO 20073849 A NO20073849 A NO 20073849A NO 20073849 L NO20073849 L NO 20073849L
- Authority
- NO
- Norway
- Prior art keywords
- viral infections
- treatment
- indole derivatives
- compounds
- viruses
- Prior art date
Links
- 208000036142 Viral infection Diseases 0.000 title abstract 2
- 230000009385 viral infection Effects 0.000 title abstract 2
- 229940054051 antipsychotic indole derivative Drugs 0.000 title 1
- 150000002475 indoles Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 241000710781 Flaviviridae Species 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
- Indole Compounds (AREA)
- Peptides Or Proteins (AREA)
Abstract
Beskrevet er forbindelser som har formel I og relaterte sammensetninger og fremgangsmater derav. Forbindelsene er anvendelige for behandling av virale infeksjoner forsaket av Flaviviridae familien av viruser.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64434305P | 2005-01-14 | 2005-01-14 | |
| PCT/US2006/001149 WO2006076529A1 (en) | 2005-01-14 | 2006-01-13 | Indole derivatives for treating viral infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20073849L true NO20073849L (no) | 2007-10-10 |
Family
ID=36143461
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20073849A NO20073849L (no) | 2005-01-14 | 2007-07-23 | Indolderivater for behandling av virale infeksjoner |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20060211698A1 (no) |
| EP (1) | EP1844042A1 (no) |
| JP (1) | JP2008526980A (no) |
| KR (1) | KR20070098914A (no) |
| CN (1) | CN101103026A (no) |
| AU (1) | AU2006204917A1 (no) |
| BR (1) | BRPI0606524A2 (no) |
| CA (1) | CA2593450A1 (no) |
| HR (1) | HRP20070342A2 (no) |
| IL (1) | IL184242A0 (no) |
| MA (1) | MA29240B1 (no) |
| MX (1) | MX2007008587A (no) |
| NO (1) | NO20073849L (no) |
| RU (1) | RU2007130896A (no) |
| TN (1) | TNSN07252A1 (no) |
| TW (1) | TW200639169A (no) |
| WO (1) | WO2006076529A1 (no) |
| ZA (1) | ZA200705872B (no) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0100623D0 (en) * | 2001-01-10 | 2001-02-21 | Vernalis Res Ltd | Chemical compounds IV |
| CA2597680A1 (en) * | 2005-02-11 | 2006-08-17 | Boehringer Ingelheim International Gmbh | Process for preparing 2,3-disubstituted indoles |
| CA2643680A1 (en) | 2006-04-11 | 2007-11-22 | Novartis Ag | Hcv/hiv inhibitors and their uses |
| US20080045498A1 (en) * | 2006-07-20 | 2008-02-21 | Genelabs Technologies, Inc. | Polycyclic viral inhibitors |
| JO3598B1 (ar) * | 2006-10-10 | 2020-07-05 | Infinity Discovery Inc | الاحماض والاسترات البورونية كمثبطات اميد هيدروليز الحامض الدهني |
| CA2674831A1 (en) | 2006-12-22 | 2008-11-13 | Schering Corporation | 5,6-ring annulated indole derivatives and methods of use thereof |
| JP5211068B2 (ja) | 2006-12-22 | 2013-06-12 | メルク・シャープ・アンド・ドーム・コーポレーション | Hcvおよび関連するウイルス疾患の治療または予防のための4,5−環インドール誘導体 |
| MX2009006880A (es) | 2006-12-22 | 2009-07-03 | Schering Corp | Derivados indolicos con anillo unido en las posiciones 4,5 para tratar o prevenir infecciones virales por virus de la hepatitis c e infecciones virales relacionadas. |
| EP2134683A2 (en) * | 2007-02-12 | 2009-12-23 | Intermune, Inc. | Novel inhibitors hepatitis c virus replication |
| CA2697500A1 (en) | 2007-08-29 | 2009-03-12 | Schering Corporation | 2,3-substituted azaindole derivatives for treating viral infections |
| EP2197842B1 (en) | 2007-08-29 | 2012-05-23 | Schering Corporation | 2, 3-substituted indole derivatives for treating viral infections |
| ES2447543T3 (es) | 2007-08-29 | 2014-03-12 | Merck Sharp & Dohme Corp. | Derivados de indol sustituidos y métodos de utilización de los mismos |
| EP2222672B1 (en) | 2007-11-16 | 2013-12-18 | Merck Sharp & Dohme Corp. | 3-aminosulfonyl substituted indole derivatives and methods of use thereof |
| CA2705586A1 (en) | 2007-11-16 | 2009-05-22 | Schering Corporation | 3-heterocyclic substituted indole derivatives and methods of use thereof |
| US8524716B2 (en) | 2007-12-24 | 2013-09-03 | Janssen R&D Ireland | Macrocyclic indoles as hepatitis C virus inhibitors |
| AU2009233711B2 (en) | 2008-04-09 | 2015-02-12 | Infinity Pharmaceuticals, Inc | Inhibitors of fatty acid amide hydrolase |
| BRPI0922366B8 (pt) * | 2008-12-03 | 2021-05-25 | Presidio Pharmaceuticals Inc | composto, composição farmacêutica e uso de um composto |
| US8143244B2 (en) * | 2009-02-26 | 2012-03-27 | Bristol-Myers Squibb Company | Cyclopropyl fused indolobenzazepine HCV NS5B inhibitors |
| US8410144B2 (en) | 2009-03-31 | 2013-04-02 | Arqule, Inc. | Substituted indolo-pyridinone compounds |
| WO2010118159A1 (en) | 2009-04-07 | 2010-10-14 | Infinity Pharmaceuticals, Inc. | Inhibitors of fatty acid amide hydrolase |
| EP2416660B1 (en) | 2009-04-07 | 2014-07-02 | Infinity Pharmaceuticals, Inc. | Inhibitors of fatty acid amide hydrolase |
| US20110182850A1 (en) | 2009-04-10 | 2011-07-28 | Trixi Brandl | Organic compounds and their uses |
| US8512690B2 (en) | 2009-04-10 | 2013-08-20 | Novartis Ag | Derivatised proline containing peptide compounds as protease inhibitors |
| EP2531511A1 (en) * | 2010-02-03 | 2012-12-12 | Infinity Pharmaceuticals, Inc. | Fatty acid amide hydrolase inhibitors |
| CN102219725B (zh) * | 2010-04-16 | 2013-10-09 | 中国科学院上海药物研究所 | 苯并杂环类化合物及其制备方法和用途 |
| EP2624826B1 (en) | 2010-10-08 | 2018-07-18 | Novartis AG | Vitamin e formulations of sulfamide ns3 inhibitors |
| CN102070520A (zh) * | 2011-01-14 | 2011-05-25 | 华东师范大学 | 以3-氧代-2,3-二芳基丙醛制备3-芳基取代喹啉的方法 |
| GB201116559D0 (en) | 2011-09-26 | 2011-11-09 | Univ Leuven Kath | Novel viral replication inhibitors |
| JOP20160086B1 (ar) | 2015-05-08 | 2021-08-17 | 2 Katholieke Univ Leuven Ku Leuven Research And Development | مشتقات اندول مستبدلة احاديا او ثنائيا بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
| KR20180030913A (ko) * | 2015-07-30 | 2018-03-26 | 브리스톨-마이어스 스큅 컴퍼니 | 아릴 치환된 비시클릭 헤테로아릴 화합물 |
| JO3633B1 (ar) | 2015-09-16 | 2020-08-27 | Katholieke Univ Leuven Ku Leuven Research & Development | مشتقات اندول مستبدلة احاديا او ثنائيا بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
| JOP20160198B1 (ar) | 2015-09-16 | 2022-03-14 | Janssen Pharmaceuticals Inc | مشتقات اندول مستبدلة احاديا او ثنائيا بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
| DK3362462T3 (da) | 2015-10-12 | 2021-10-11 | Advanced Cell Diagnostics Inc | In situ-detektion af nukleotidvarianter i prøver med højt støjniveau, og sammensætninger og fremgangsmåder relateret dertil |
| SG11201808138YA (en) | 2016-03-31 | 2018-10-30 | Janssen Pharmaceuticals Inc | Substituted indole derivatives as dengue viral replication inhibitors |
| MA44498A (fr) | 2016-03-31 | 2019-02-06 | Janssen Pharmaceuticals Inc | Dérivés d'indoline substituée utilisés en tant qu'inhibiteurs de la réplication du virus de la dengue |
| JOP20170069B1 (ar) | 2016-04-01 | 2021-08-17 | 1 Janssen Pharmaceuticals Inc | مشتقات اندولين مستبدلة بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
| EP3436004B1 (en) | 2016-04-01 | 2024-12-11 | Janssen Pharmaceuticals, Inc. | Substituted indole compound derivatives as dengue viral replication inhibitors |
| CN106008306A (zh) * | 2016-06-28 | 2016-10-12 | 山东大学 | 取代吲哚类衍生物及其制备方法与应用 |
| JP6903732B2 (ja) | 2016-07-14 | 2021-07-14 | ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company | Par4阻害剤としての三環式ヘテロアリール置換のキノリンおよびアザキノリン化合物 |
| WO2018013774A1 (en) | 2016-07-14 | 2018-01-18 | Bristol-Myers Squibb Company | Bicyclic heteroaryl substituted compounds |
| US10730868B2 (en) | 2016-07-14 | 2020-08-04 | Bristol-Myers Squibb Company | Bicyclic heteroaryl substituted compounds |
| JOP20180025B1 (ar) | 2017-03-31 | 2021-08-17 | Janssen Pharmaceuticals Inc | مشتقات اندولين مستبدلة بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
| JOP20180026A1 (ar) | 2017-03-31 | 2019-01-30 | Univ Leuven Kath | مشتقات اندولين مستبدلة بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
| SI3630724T1 (sl) | 2017-05-22 | 2021-08-31 | Janssen Pharmaceuticals, Inc. | Substituirani derivati indolina kot zaviralci replikacije virusa denga |
| CA3060583C (en) | 2017-05-22 | 2024-06-04 | Janssen Pharmaceuticals, Inc. | Substituted indoline derivatives as dengue viral replication inhibitors |
| WO2023044364A1 (en) | 2021-09-15 | 2023-03-23 | Enko Chem, Inc. | Protoporphyrinogen oxidase inhibitors |
| CN115304584B (zh) * | 2022-07-25 | 2023-05-26 | 云南大学 | 3-硫甲基-(5’-芳基-1h-吡唑)-吲哚类化合物及其制备方法和用途 |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1584735A (no) * | 1968-03-20 | 1970-01-02 | ||
| US4360317A (en) * | 1980-08-01 | 1982-11-23 | Ford Motor Company | Three cycle per revolution wave compression supercharger |
| FR2674855B1 (fr) * | 1991-04-03 | 1994-01-14 | Synthelabo | Derives de piperidine, leur preparation et leur application en therapeutique. |
| DE4129603A1 (de) * | 1991-09-06 | 1993-03-11 | Thomae Gmbh Dr K | Kondensierte 5-gliedrige heterocyclen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| US5814651A (en) * | 1992-12-02 | 1998-09-29 | Pfizer Inc. | Catechol diethers as selective PDEIV inhibitors |
| US5563143A (en) * | 1994-09-21 | 1996-10-08 | Pfizer Inc. | Catechol diether compounds as inhibitors of TNF release |
| EP0882718B1 (en) * | 1995-12-28 | 2005-08-31 | Fujisawa Pharmaceutical Co., Ltd. | Benzimidazole derivatives |
| US5633388A (en) * | 1996-03-29 | 1997-05-27 | Viropharma Incorporated | Compounds, compositions and methods for treatment of hepatitis C |
| DE19615262A1 (de) * | 1996-04-18 | 1997-10-23 | Bayer Ag | Heteroverknüpfte Phenylglycinolamide |
| US6207679B1 (en) * | 1997-06-19 | 2001-03-27 | Sepracor, Inc. | Antimicrobial agents uses and compositions related thereto |
| US5932743A (en) * | 1997-08-21 | 1999-08-03 | American Home Products Corporation | Methods for the solid phase synthesis of substituted indole compounds |
| CN1299358A (zh) * | 1997-12-31 | 2001-06-13 | 新泽西州州立大学(拉特格斯) | 杂环拓扑异构酶毒性剂 |
| SK7522001A3 (en) * | 1998-03-31 | 2002-02-05 | Inst For Pharm Discovery Inc | Substituted indolealkanoic acids |
| US6211177B1 (en) * | 1998-11-24 | 2001-04-03 | Cell Pathways, Inc. | Method for treating neoplasia by exposure to substituted 2-aryl-benzimidazole derivatives |
| US6358992B1 (en) * | 1998-11-25 | 2002-03-19 | Cell Pathways, Inc. | Method of inhibiting neoplastic cells with indole derivatives |
| US6358986B1 (en) * | 1999-01-19 | 2002-03-19 | Boehringer Ingelheim Pharma Kg | Polymorphs of telmisartan |
| GB9914825D0 (en) * | 1999-06-24 | 1999-08-25 | Smithkline Beecham Spa | Novel compounds |
| US6770666B2 (en) * | 1999-12-27 | 2004-08-03 | Japan Tobacco Inc. | Fused-ring compounds and use thereof as drugs |
| GB0003397D0 (en) * | 2000-02-14 | 2000-04-05 | Merck Sharp & Dohme | Therapeutic agents |
| US6605615B2 (en) * | 2000-03-01 | 2003-08-12 | Tularik Inc. | Hydrazones and analogs as cholesterol lowering agents |
| US6310212B1 (en) * | 2000-03-28 | 2001-10-30 | Neurogen Corporation | 4-substituted quinoline derivatives |
| WO2002000620A1 (en) * | 2000-06-27 | 2002-01-03 | Smithkline Beecham Corporation | Fatty acid synthase inhibitors |
| US6448281B1 (en) * | 2000-07-06 | 2002-09-10 | Boehringer Ingelheim (Canada) Ltd. | Viral polymerase inhibitors |
| US6864265B2 (en) * | 2000-09-15 | 2005-03-08 | Anormed, Inc. | Chemokine receptor binding heterocyclic compounds |
| CA2436133A1 (en) * | 2001-01-29 | 2002-08-08 | University Of Connecticut | Receptor selective cannabimimetic aminoalkylindoles |
| WO2002076454A1 (en) * | 2001-03-26 | 2002-10-03 | Unisearch Limited | Method for treatment of cancer and compositions for use therein |
| EP2335700A1 (en) * | 2001-07-25 | 2011-06-22 | Boehringer Ingelheim (Canada) Ltd. | Hepatitis C virus polymerase inhibitors with a heterobicylic structure |
| FR2831536A1 (fr) * | 2001-10-26 | 2003-05-02 | Aventis Pharma Sa | Nouveaux derives de benzimidazoles, leur procede de preparation, leur application a titre de medicament, compositions pharmaceutiques et nouvelle utilisation notamment comme inhibiteurs de kdr |
| US6737432B2 (en) * | 2001-10-31 | 2004-05-18 | Boehringer Ingelheim Pharma Kg | Crystalline form of telmisartan sodium |
| SE0104331D0 (sv) * | 2001-12-19 | 2001-12-19 | Astrazeneca Ab | Novel compounds |
| KR100985140B1 (ko) * | 2001-12-20 | 2010-10-05 | 와이어쓰 엘엘씨 | 5-하이드록시트립타민-6 리간드로서의 인돌릴알킬아민 유도체 |
| US20050075331A1 (en) * | 2003-10-06 | 2005-04-07 | Pratt John K. | Anti-infective agents |
| DE10253426B4 (de) * | 2002-11-15 | 2005-09-22 | Elbion Ag | Neue Hydroxyindole, deren Verwendung als Inhibitoren der Phosphodiesterase 4 und Verfahren zu deren Herstellung |
| US7151114B2 (en) * | 2003-01-09 | 2006-12-19 | Boehringer Ingelheim International Gmbh | Use of substituted 2-phenylbenzimidazoles as medicaments |
| US7223785B2 (en) * | 2003-01-22 | 2007-05-29 | Boehringer Ingelheim International Gmbh | Viral polymerase inhibitors |
| US20050020654A1 (en) * | 2003-03-15 | 2005-01-27 | Pershadsingh Harrihar A. | Novel PPAR agonists, pharmaceutical compositions and uses thereof |
| GB0307891D0 (en) * | 2003-04-04 | 2003-05-14 | Angeletti P Ist Richerche Bio | Chemical compounds,compositions and uses |
| CA2534649A1 (en) * | 2003-08-01 | 2005-02-10 | Genelabs Technologies, Inc. | Bicyclic imidazol derivatives against flaviviridae |
| US7378414B2 (en) * | 2003-08-25 | 2008-05-27 | Abbott Laboratories | Anti-infective agents |
| US20050119318A1 (en) * | 2003-10-31 | 2005-06-02 | Hudyma Thomas W. | Inhibitors of HCV replication |
| WO2005090302A2 (en) * | 2004-03-16 | 2005-09-29 | Boehringer Ingelheim International Gmbh | Palladium catalyzed indolization of 2-bromo or chloroanilines |
| UY29017A1 (es) * | 2004-07-16 | 2006-02-24 | Boehringer Ingelheim Int | Inhibidores de polimerasa viral |
-
2006
- 2006-01-13 US US11/331,578 patent/US20060211698A1/en not_active Abandoned
- 2006-01-13 EP EP06718244A patent/EP1844042A1/en not_active Withdrawn
- 2006-01-13 JP JP2007551384A patent/JP2008526980A/ja not_active Withdrawn
- 2006-01-13 RU RU2007130896/04A patent/RU2007130896A/ru not_active Application Discontinuation
- 2006-01-13 CN CNA2006800021868A patent/CN101103026A/zh active Pending
- 2006-01-13 BR BRPI0606524-4A patent/BRPI0606524A2/pt not_active IP Right Cessation
- 2006-01-13 ZA ZA200705872A patent/ZA200705872B/xx unknown
- 2006-01-13 HR HR20070342A patent/HRP20070342A2/xx not_active Application Discontinuation
- 2006-01-13 MX MX2007008587A patent/MX2007008587A/es not_active Application Discontinuation
- 2006-01-13 CA CA002593450A patent/CA2593450A1/en not_active Abandoned
- 2006-01-13 WO PCT/US2006/001149 patent/WO2006076529A1/en not_active Ceased
- 2006-01-13 KR KR1020077018663A patent/KR20070098914A/ko not_active Withdrawn
- 2006-01-13 AU AU2006204917A patent/AU2006204917A1/en not_active Abandoned
- 2006-01-16 TW TW095101609A patent/TW200639169A/zh unknown
-
2007
- 2007-06-26 IL IL184242A patent/IL184242A0/en unknown
- 2007-07-03 TN TNP2007000252A patent/TNSN07252A1/en unknown
- 2007-07-23 NO NO20073849A patent/NO20073849L/no not_active Application Discontinuation
- 2007-07-26 MA MA30113A patent/MA29240B1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006076529A1 (en) | 2006-07-20 |
| RU2007130896A (ru) | 2009-02-20 |
| TNSN07252A1 (en) | 2008-12-31 |
| HRP20070342A2 (hr) | 2007-10-31 |
| CN101103026A (zh) | 2008-01-09 |
| MX2007008587A (es) | 2007-09-07 |
| AU2006204917A1 (en) | 2006-07-20 |
| JP2008526980A (ja) | 2008-07-24 |
| IL184242A0 (en) | 2007-10-31 |
| BRPI0606524A2 (pt) | 2009-06-30 |
| US20060211698A1 (en) | 2006-09-21 |
| KR20070098914A (ko) | 2007-10-05 |
| EP1844042A1 (en) | 2007-10-17 |
| CA2593450A1 (en) | 2006-07-20 |
| ZA200705872B (en) | 2008-09-25 |
| MA29240B1 (fr) | 2008-02-01 |
| TW200639169A (en) | 2006-11-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TNSN07252A1 (en) | Indole derivatives for treating viral infections | |
| EA200702493A1 (ru) | Соединения и способы лечения или предотвращения флавивирусных инфекций | |
| NO20092053L (no) | HCV NS3-proteaseinhibitorer | |
| NO341663B1 (no) | Cyklopropyl-kondenserte indolobenzaepin HCV NS5B inhibitorer | |
| NO20080879L (no) | HCV-NS3-proteaseinhibitorer | |
| EA201000201A1 (ru) | Азотсодержащие бициклические химические вещества для лечения вирусных инфекций | |
| NO20062146L (no) | Nukleosidforbindelser for behandling av virusinfeksjoner | |
| NO20074613L (no) | Tricykliske nukleosidforbindelser for behandling av virale infeksjoner | |
| NO20084645L (no) | Cyklopropyl kondenserte indolobenzazepin HCV NS5B inhibitorer | |
| NO20063479L (no) | Fosfonater, monofosfonamidater og bis-fosfonamidater for behandling av virussykdommer | |
| EA200901241A1 (ru) | Соединения для лечения гепатита с | |
| EA201101492A1 (ru) | Аналоги тиофена для лечения или предупреждения флавивирусных инфекций | |
| NO20073105L (no) | Pyridazinonforbindelser | |
| NO20081217L (no) | Nye benzotiazolonderivater | |
| NO20091553L (no) | Fenylderivater og deres anvendelse som immunmodulatorer | |
| WO2006119061A3 (en) | Hcv ns3 protease inhibitors | |
| NO20074275L (no) | 2- (4-okso-4H-kinazolin-3-yl) acetamider og deres anvendelse som Vasopressin-V3-antagonister | |
| TW200720285A (en) | Nucleoside compounds for treating viral infections | |
| WO2008057208A3 (en) | Hcv ns3 protease inhibitors | |
| WO2008051514A3 (en) | Hcv ns3 protease inhibitors | |
| WO2008051475A3 (en) | Hcv ns3 protease inhibitors | |
| EA200901101A1 (ru) | Макроциклические соединения в качестве ингибиторов протеазы ns3 вгс | |
| NO20082096L (no) | Azaindol-2-karboksamidderivativer | |
| NO20083065L (no) | Nye N-sulfamoylpiperidinamider for profylakse eller behandling av overvekt og beslektede tilstander | |
| TW200719898A (en) | 6-membered aryl and heteroaryl derivatives for treating viruses |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |