NO20074267L - Konjugater av biologisk aktive proteiner som har en modifisert in vivo halveringstid - Google Patents
Konjugater av biologisk aktive proteiner som har en modifisert in vivo halveringstidInfo
- Publication number
- NO20074267L NO20074267L NO20074267A NO20074267A NO20074267L NO 20074267 L NO20074267 L NO 20074267L NO 20074267 A NO20074267 A NO 20074267A NO 20074267 A NO20074267 A NO 20074267A NO 20074267 L NO20074267 L NO 20074267L
- Authority
- NO
- Norway
- Prior art keywords
- biologically active
- life
- modified
- polypeptide
- conjugates
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 5
- 108090000623 proteins and genes Proteins 0.000 title abstract 5
- 238000001727 in vivo Methods 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 5
- 229920001184 polypeptide Polymers 0.000 abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 4
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64711905P | 2005-01-25 | 2005-01-25 | |
| US71258505P | 2005-08-30 | 2005-08-30 | |
| PCT/US2006/002501 WO2006081249A2 (en) | 2005-01-25 | 2006-01-25 | Conjugates of biologically active proteins having a modified in vivo half-life |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20074267L true NO20074267L (no) | 2007-09-28 |
Family
ID=36644921
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20074267A NO20074267L (no) | 2005-01-25 | 2007-08-21 | Konjugater av biologisk aktive proteiner som har en modifisert in vivo halveringstid |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US8129348B2 (pt) |
| EP (1) | EP1841787A2 (pt) |
| JP (2) | JP5735194B2 (pt) |
| KR (1) | KR101608083B1 (pt) |
| CN (1) | CN103172747A (pt) |
| AU (1) | AU2006208199B2 (pt) |
| BR (1) | BRPI0606934A2 (pt) |
| CA (1) | CA2595695A1 (pt) |
| IL (1) | IL184763A (pt) |
| MX (1) | MX2007008982A (pt) |
| NO (1) | NO20074267L (pt) |
| NZ (1) | NZ556726A (pt) |
| RU (1) | RU2007132188A (pt) |
| WO (1) | WO2006081249A2 (pt) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0606934A2 (pt) * | 2005-01-25 | 2017-07-11 | Cell Therapeutics Inc | Conjugado de proteína biologicamente ativa, composição, molécula de dna quimérica, vetor, célula, e, métodos para preparar conjugado de proteína biologicamente ativa, e para determinar se um dado conjugado de proteína exibe uma meia-vida de plasma modificada comparada com a meia-vida intrínseca do polipeptídeo biologicamente ativo não conjungado |
| US7846445B2 (en) | 2005-09-27 | 2010-12-07 | Amunix Operating, Inc. | Methods for production of unstructured recombinant polymers and uses thereof |
| US7855279B2 (en) * | 2005-09-27 | 2010-12-21 | Amunix Operating, Inc. | Unstructured recombinant polymers and uses thereof |
| EP2402754B2 (en) † | 2006-03-06 | 2023-07-26 | Amunix Operating Inc. | Unstructured recombinant polymers and uses thereof |
| AU2007223855B2 (en) * | 2006-03-06 | 2013-05-16 | Amunix Operating Inc. | Unstructured recombinant polymers and uses thereof |
| US8592374B2 (en) | 2007-03-16 | 2013-11-26 | Research Foundation For Mental Hygiene, Inc. | Neurotrophic peptides |
| EP2009103A1 (en) * | 2007-03-16 | 2008-12-31 | Ebewe Pharma Ges.m.b.H. Nfg. KG | Neurotrophic peptides |
| AU2013203326B2 (en) * | 2007-06-21 | 2013-08-01 | Technische Universitat Munchen | Biological active proteins having increased in vivo and/or in vitro stability |
| SI2173890T1 (sl) | 2007-06-21 | 2011-06-30 | Univ Muenchen Tech | Biološko aktivni proteini, ki imajo povečano in vivo in/ali in vitro stabilnost |
| JP2010536341A (ja) | 2007-08-15 | 2010-12-02 | アムニクス, インコーポレイテッド | 生物学的に活性なポリペプチドの特性を改変するための組成物および方法 |
| EP2197897A4 (en) * | 2007-08-30 | 2012-08-08 | Univ Waterloo | AMINO ACID-BASED SELF-ASSOCIATED PEPTIDES AND METHODS |
| CN103864895A (zh) | 2008-12-29 | 2014-06-18 | 隆萨布莱纳公司 | 制备比伐卢定的方法 |
| US8680050B2 (en) | 2009-02-03 | 2014-03-25 | Amunix Operating Inc. | Growth hormone polypeptides fused to extended recombinant polypeptides and methods of making and using same |
| ES2610356T3 (es) | 2009-02-03 | 2017-04-27 | Amunix Operating Inc. | Polipéptidos recombinantes extendidos y composiciones que comprenden los mismos |
| JP5499296B2 (ja) * | 2009-02-03 | 2014-05-21 | 国立大学法人東京農工大学 | 細胞の吸着を制御可能なポリペプチド |
| US8703717B2 (en) | 2009-02-03 | 2014-04-22 | Amunix Operating Inc. | Growth hormone polypeptides and methods of making and using same |
| WO2010144508A1 (en) | 2009-06-08 | 2010-12-16 | Amunix Operating Inc. | Glucose-regulating polypeptides and methods of making and using same |
| US9849188B2 (en) | 2009-06-08 | 2017-12-26 | Amunix Operating Inc. | Growth hormone polypeptides and methods of making and using same |
| CA2771999A1 (en) * | 2009-08-24 | 2011-03-10 | Amunix Operating Inc. | Coagulation factor vii compositions and methods of making and using same |
| US8557961B2 (en) | 2010-04-02 | 2013-10-15 | Amunix Operating Inc. | Alpha 1-antitrypsin compositions and methods of making and using same |
| US9221882B2 (en) | 2010-05-21 | 2015-12-29 | Technische Universitat Munchen | Biosynthetic proline/alanine random coil polypeptides and their uses |
| US9539324B2 (en) | 2010-12-01 | 2017-01-10 | Alderbio Holdings, Llc | Methods of preventing inflammation and treating pain using anti-NGF compositions |
| US11214610B2 (en) | 2010-12-01 | 2022-01-04 | H. Lundbeck A/S | High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris |
| EP2646468B1 (en) | 2010-12-01 | 2018-07-25 | AlderBio Holdings LLC | Anti-ngf compositions and use thereof |
| US9078878B2 (en) | 2010-12-01 | 2015-07-14 | Alderbio Holdings Llc | Anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75 |
| US9884909B2 (en) | 2010-12-01 | 2018-02-06 | Alderbio Holdings Llc | Anti-NGF compositions and use thereof |
| US9067988B2 (en) | 2010-12-01 | 2015-06-30 | Alderbio Holdings Llc | Methods of preventing or treating pain using anti-NGF antibodies |
| AU2012296951B2 (en) | 2011-08-12 | 2016-09-15 | Ascendis Pharma A/S | Protein carrier-linked prodrugs |
| JP6256882B2 (ja) | 2012-02-15 | 2018-01-10 | アムニクス オペレーティング インコーポレイテッド | 第viii因子組成物、ならびに組成物の作製方法および用途 |
| EP2822577B1 (en) | 2012-02-15 | 2019-02-06 | Bioverativ Therapeutics Inc. | Recombinant factor viii proteins |
| JP6355563B2 (ja) | 2012-02-27 | 2018-07-11 | アムニクス オペレーティング インコーポレイテッド | Xten共役組成物およびそれを製造する方法 |
| AU2013263349B2 (en) | 2012-05-17 | 2016-09-08 | Extend Biosciences, Inc | Carriers for improved drug delivery |
| KR102121086B1 (ko) | 2012-11-01 | 2020-06-09 | 팩터 바이오사이언스 인크. | 세포에서 단백질을 발현시키는 방법들과 생성물들 |
| TW202003554A (zh) | 2013-08-14 | 2020-01-16 | 美商百歐維拉提夫治療公司 | 因子viii-xten融合物及其用途 |
| US9789197B2 (en) | 2014-10-22 | 2017-10-17 | Extend Biosciences, Inc. | RNAi vitamin D conjugates |
| WO2016065042A1 (en) | 2014-10-22 | 2016-04-28 | Extend Biosciences, Inc. | Therapeutic vitamin d conjugates |
| US9616109B2 (en) | 2014-10-22 | 2017-04-11 | Extend Biosciences, Inc. | Insulin vitamin D conjugates |
| CA2976376A1 (en) | 2015-02-13 | 2016-08-18 | Factor Bioscience Inc. | Nucleic acid products and methods of administration thereof |
| CN104988107B (zh) * | 2015-05-19 | 2018-06-08 | 中国农业科学院兰州兽医研究所 | 一种高效表达口蹄疫病毒抗原基因的重组乳酸杆菌及其制备方法和应用 |
| ES2784603T3 (es) * | 2015-06-02 | 2020-09-29 | Novo Nordisk As | Insulinas con extensiones recombinantes polares |
| EA201890423A1 (ru) | 2015-08-03 | 2018-07-31 | Биовератив Терапьютикс Инк. | Слитые белки фактора ix, способы их получения и применения |
| IL319047A (en) | 2015-08-28 | 2025-04-01 | Amunix Operating Inc | Chimeric polypeptide composition and methods for its preparation and use |
| EP3355931B1 (en) | 2015-10-01 | 2024-06-26 | Novo Nordisk A/S | Protein conjugates |
| IL308824A (en) | 2016-08-17 | 2024-01-01 | Factor Bioscience Inc | Nucleic acid products and methods of administration thereof |
| MX2019006444A (es) | 2016-12-02 | 2019-10-30 | Bioverativ Therapeutics Inc | Métodos de tratamiento de artropatía hemofílica utilizando factores de coagulación quiméricos. |
| MX2019008827A (es) | 2017-01-30 | 2019-09-26 | Alexion Pharma Inc | Anticuerpos anti-properdina monovalentes y fragmentos de anticuerpo. |
| JP2020513019A (ja) | 2017-04-05 | 2020-04-30 | ノヴォ ノルディスク アー/エス | オリゴマー伸長インスリン−Fcコンジュゲート |
| AU2018393111B2 (en) | 2017-12-21 | 2025-07-10 | Amunix Pharmaceuticals, Inc. | Release segments and binding compositions comprising same |
| PL3793588T3 (pl) | 2018-05-18 | 2025-09-01 | Bioverativ Therapeutics Inc. | Sposoby leczenia hemofilii a |
| CA3145425A1 (en) | 2019-07-03 | 2021-01-07 | Factor Bioscience Inc. | Cationic lipids and uses thereof |
| US10501404B1 (en) | 2019-07-30 | 2019-12-10 | Factor Bioscience Inc. | Cationic lipids and transfection methods |
| JP7398716B2 (ja) * | 2019-11-05 | 2023-12-15 | 国立大学法人京都大学 | ペプチド、組成物、及び、気分障害を治療、予防、又は改善する方法 |
| CN112608366B (zh) * | 2020-12-31 | 2024-08-30 | 中国药科大学 | 超正电荷聚多肽及其制备方法、应用 |
| CN113480667B (zh) * | 2021-08-17 | 2023-03-28 | 长春萤火虫生物科技有限公司 | 一种人粒细胞集落刺激因子突变体重组融合蛋白及其制备方法和应用 |
| KR20250075704A (ko) | 2022-09-30 | 2025-05-28 | 익스텐드 바이오사이언시즈, 인크. | 장기-지속형 부갑상선 호르몬 |
| WO2024128079A1 (ja) * | 2022-12-16 | 2024-06-20 | 東亞合成株式会社 | 合成ペプチド及び構築物 |
| CN120112542A (zh) * | 2023-09-27 | 2025-06-06 | 京东方科技集团股份有限公司 | 针对亨廷顿舞蹈症的早期诊断的多肽探针和试剂盒 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4810643A (en) | 1985-08-23 | 1989-03-07 | Kirin- Amgen Inc. | Production of pluripotent granulocyte colony-stimulating factor |
| JP3045539B2 (ja) * | 1989-02-21 | 2000-05-29 | ワシントン ユニバーシティ | 改変型生殖ホルモン |
| US5824784A (en) | 1994-10-12 | 1998-10-20 | Amgen Inc. | N-terminally chemically modified protein compositions and methods |
| US6455678B1 (en) | 1996-04-26 | 2002-09-24 | Amcell Corporation | Human hematopoietic stem and progenitor cell antigen |
| CN1240479A (zh) * | 1996-07-09 | 2000-01-05 | 安姆根有限公司 | 截短的可溶性肿瘤坏死因子i-型和ii-型受体 |
| EP0979102A4 (en) | 1997-04-30 | 2005-11-23 | Enzon Inc | DETAILED POLYPEPTIDE MODIFIED BY POLYALKYLENE OXIDE |
| ES2341217T3 (es) | 1999-01-19 | 2010-06-17 | Maxygen, Inc. | Recombinacion de acidos nucleicos mediada por oligonucleotidos. |
| CZ299516B6 (cs) | 1999-07-02 | 2008-08-20 | F. Hoffmann-La Roche Ag | Konjugát erythropoetinového glykoproteinu, zpusobjeho výroby a použití a farmaceutická kompozice sjeho obsahem |
| US6831158B2 (en) | 2000-01-10 | 2004-12-14 | Maxygen Holdings Ltd. | G-CSF conjugates |
| CA2412882A1 (en) * | 2000-06-30 | 2002-01-10 | Maxygen Aps | Peptide extended glycosylated polypeptides |
| CA2513287A1 (en) | 2002-01-14 | 2003-07-17 | William Herman | Multispecific binding molecules |
| DE102004049479A1 (de) | 2004-10-11 | 2006-04-13 | Scil Proteins Gmbh | Proteinkonjugate zur Verwendung in Therapie, Diagnose und Chromatographie |
| ZA200707006B (en) * | 2005-01-25 | 2008-11-26 | Cell Therapeutics Inc | Conjugates of biologically active proteins having a modified in vivo half-life |
| BRPI0606934A2 (pt) * | 2005-01-25 | 2017-07-11 | Cell Therapeutics Inc | Conjugado de proteína biologicamente ativa, composição, molécula de dna quimérica, vetor, célula, e, métodos para preparar conjugado de proteína biologicamente ativa, e para determinar se um dado conjugado de proteína exibe uma meia-vida de plasma modificada comparada com a meia-vida intrínseca do polipeptídeo biologicamente ativo não conjungado |
-
2006
- 2006-01-25 BR BRPI0606934A patent/BRPI0606934A2/pt not_active IP Right Cessation
- 2006-01-25 WO PCT/US2006/002501 patent/WO2006081249A2/en not_active Ceased
- 2006-01-25 EP EP06733852A patent/EP1841787A2/en not_active Withdrawn
- 2006-01-25 NZ NZ556726A patent/NZ556726A/en not_active IP Right Cessation
- 2006-01-25 KR KR1020077019500A patent/KR101608083B1/ko not_active Expired - Fee Related
- 2006-01-25 JP JP2007552379A patent/JP5735194B2/ja not_active Expired - Fee Related
- 2006-01-25 MX MX2007008982A patent/MX2007008982A/es active IP Right Grant
- 2006-01-25 AU AU2006208199A patent/AU2006208199B2/en not_active Ceased
- 2006-01-25 CN CN2013100130797A patent/CN103172747A/zh active Pending
- 2006-01-25 CA CA002595695A patent/CA2595695A1/en not_active Abandoned
- 2006-01-25 RU RU2007132188/13A patent/RU2007132188A/ru not_active Application Discontinuation
-
2007
- 2007-07-22 IL IL184763A patent/IL184763A/en not_active IP Right Cessation
- 2007-08-21 NO NO20074267A patent/NO20074267L/no not_active Application Discontinuation
-
2008
- 2008-10-14 US US12/251,324 patent/US8129348B2/en not_active Expired - Fee Related
-
2012
- 2012-01-31 US US13/363,278 patent/US8748577B2/en not_active Expired - Fee Related
- 2012-11-30 JP JP2012263866A patent/JP2013100292A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR20070119622A (ko) | 2007-12-20 |
| NZ556726A (en) | 2011-04-29 |
| AU2006208199A1 (en) | 2006-08-03 |
| EP1841787A2 (en) | 2007-10-10 |
| IL184763A0 (en) | 2007-12-03 |
| JP2013100292A (ja) | 2013-05-23 |
| US8129348B2 (en) | 2012-03-06 |
| US20120252717A1 (en) | 2012-10-04 |
| WO2006081249A8 (en) | 2007-09-13 |
| CA2595695A1 (en) | 2006-08-03 |
| IL184763A (en) | 2013-05-30 |
| US20090298762A1 (en) | 2009-12-03 |
| AU2006208199B2 (en) | 2012-06-07 |
| JP2008528002A (ja) | 2008-07-31 |
| WO2006081249A3 (en) | 2007-02-01 |
| WO2006081249A2 (en) | 2006-08-03 |
| MX2007008982A (es) | 2007-12-06 |
| WO2006081249A9 (en) | 2007-07-26 |
| JP5735194B2 (ja) | 2015-06-17 |
| CN103172747A (zh) | 2013-06-26 |
| US8748577B2 (en) | 2014-06-10 |
| RU2007132188A (ru) | 2009-03-10 |
| KR101608083B1 (ko) | 2016-04-01 |
| BRPI0606934A2 (pt) | 2017-07-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |