NO20074740L - Fremgangsmater for anvendelse av dodsreseptoragonister og EGFR-inhibitorer - Google Patents
Fremgangsmater for anvendelse av dodsreseptoragonister og EGFR-inhibitorerInfo
- Publication number
- NO20074740L NO20074740L NO20074740A NO20074740A NO20074740L NO 20074740 L NO20074740 L NO 20074740L NO 20074740 A NO20074740 A NO 20074740A NO 20074740 A NO20074740 A NO 20074740A NO 20074740 L NO20074740 L NO 20074740L
- Authority
- NO
- Norway
- Prior art keywords
- death receptor
- egfr inhibitors
- methods
- receptor agonists
- antibodies
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/061,258 US20060188498A1 (en) | 2005-02-18 | 2005-02-18 | Methods of using death receptor agonists and EGFR inhibitors |
| PCT/US2006/005459 WO2006089015A2 (en) | 2005-02-18 | 2006-02-16 | Methods of using death receptor agonists and egfr inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20074740L true NO20074740L (no) | 2007-11-14 |
Family
ID=36912953
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20074740A NO20074740L (no) | 2005-02-18 | 2007-09-17 | Fremgangsmater for anvendelse av dodsreseptoragonister og EGFR-inhibitorer |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20060188498A1 (pt) |
| EP (1) | EP1853300B1 (pt) |
| JP (2) | JP2008532937A (pt) |
| KR (1) | KR20070110852A (pt) |
| CN (1) | CN101180072A (pt) |
| AU (1) | AU2006214292A1 (pt) |
| BR (1) | BRPI0606360A2 (pt) |
| CA (1) | CA2595931A1 (pt) |
| IL (1) | IL184827A0 (pt) |
| NO (1) | NO20074740L (pt) |
| RU (1) | RU2429006C2 (pt) |
| WO (1) | WO2006089015A2 (pt) |
| ZA (1) | ZA200706859B (pt) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007530588A (ja) * | 2004-03-23 | 2007-11-01 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | レセプターカップリング剤およびその治療用途 |
| CA2778435A1 (en) * | 2008-11-06 | 2010-05-14 | Wayne State University | Vaccines targeting cellular death receptors |
| EP2480230A4 (en) * | 2009-09-24 | 2015-06-10 | Seattle Genetics Inc | DR5 Ligand-HEILMITTELKONJUGATE |
| US20130064838A1 (en) * | 2010-05-14 | 2013-03-14 | Amgen Inc. | Enhanced death receptor agonists |
| IT1402029B1 (it) | 2010-10-14 | 2013-08-28 | Italiana Sint Spa | Procedimento per la preparazione di erlotinib |
| ITPD20110091A1 (it) * | 2011-03-24 | 2012-09-25 | Univ Padova | Inibitori multitirosinchinasi utili per le patologie correlate: modelli farmacoforici, composti identificati tramite questi modelli, metodi per la loro preparazione, la loro formulazione e il loro impiego terapeutico. |
| MX2013012716A (es) * | 2011-05-03 | 2014-03-21 | Genentech Inc | Agentes de disociacion vascular y sus usos. |
| CN102675225A (zh) * | 2012-05-16 | 2012-09-19 | 浙江理工大学 | 一种盐酸埃罗替尼的合成方法 |
| RU2580220C2 (ru) * | 2012-11-07 | 2016-04-10 | Федеральное Государственное Бюджетное Учреждение Науки Институт Молекулярной Биологии Им. В.А. Энгельгардта Российской Академии Наук (Имб Ран) | РЕКОМБИНАНТНАЯ ПЛАЗМИДА рСрG-СytDA/upp ДЛЯ ЭКСПРЕССИ ГИБРИДНОГО БЕЛКА ЦИТОЗИНДЕЗАМИНАЗА-УРАЦИЛФОСФОРИБОЗИЛ ТРАНСФЕРАЗА, РЕКОМБИНАНТНАЯ ПЛАЗМИДА рСрG-СytDA/upp/VP22 ДЛЯ ЭКСПРЕССИИ ГИБРИДНОГО БЕЛКА ЦИТОЗИНДЕЗАМИНАЗА-УРАЦИЛФОСФОРИБОЗИЛ ТРАНСФЕРЕЗА-VP22, ЛЕЧЕБНАЯ КОМПОЗИЦИЯ ДЛЯ ТЕРАПИИ ОНКОЛОГИЧЕСКИХ ЗАБОЛЕВАНИЙ И СПОСОБ ЕЕ ПРИМЕНЕНИЯ |
| US9556203B2 (en) * | 2013-10-04 | 2017-01-31 | Piqur Therapeutics Ag | Conformationally restricted P13K and mTOR inhibitors |
| CN103833853B (zh) * | 2013-12-25 | 2019-05-17 | 河南大学 | 新型死亡受体激动性多价抗体及其在制备抗肿瘤药物中的应用 |
| WO2015138638A1 (en) | 2014-03-11 | 2015-09-17 | Theraly Pharmaceuticals, Inc. | Long acting trail receptor agonists for treatment of autoimmune diseases |
| JP6629753B2 (ja) * | 2014-04-03 | 2020-01-15 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung | がん治療剤の組合せ |
| NO2776305T3 (pt) * | 2014-04-23 | 2018-01-27 | ||
| EP3229806A1 (en) | 2014-12-12 | 2017-10-18 | Merck Patent GmbH | Combination of a 6-oxo-1,6-dihydro-pyridazine derivative having anti-cancer activity with an egfr inhibitor |
| CN105801495A (zh) * | 2014-12-31 | 2016-07-27 | 徐州万邦金桥制药有限公司 | 一种盐酸厄洛替尼合成纯化方法 |
| DK3389696T3 (da) | 2015-12-17 | 2024-12-16 | Univ Johns Hopkins | Ameliorating systemic sclerosis with death receptor agonists |
| KR102508650B1 (ko) | 2016-04-07 | 2023-03-13 | 더 존스 홉킨스 유니버시티 | 사멸 수용체 작용제로써 췌장암 및 통증을 치료하기 위한 조성물 및 방법 |
| JP7197370B2 (ja) * | 2016-06-17 | 2022-12-27 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | がんの予防および/または治療のための化合物、組成物および方法 |
| WO2019154230A1 (zh) * | 2018-02-08 | 2019-08-15 | 四川大学华西医院 | 一种包含TRAIL和IgG结合结构域的融合蛋白及其用途 |
| US11767353B2 (en) | 2020-06-05 | 2023-09-26 | Theraly Fibrosis, Inc. | Trail compositions with reduced immunogenicity |
| TW202309022A (zh) | 2021-04-13 | 2023-03-01 | 美商努法倫特公司 | 用於治療具egfr突變之癌症之胺基取代雜環 |
| CN119371319A (zh) * | 2024-10-25 | 2025-01-28 | 安徽尖峰北卡药业有限公司 | 一种用于埃罗替尼中间体生产工艺及其生产系统 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| US4657760A (en) | 1979-03-20 | 1987-04-14 | Ortho Pharmaceutical Corporation | Methods and compositions using monoclonal antibody to human T cells |
| GB8430252D0 (en) | 1984-11-30 | 1985-01-09 | Beecham Group Plc | Compounds |
| US5206344A (en) | 1985-06-26 | 1993-04-27 | Cetus Oncology Corporation | Interleukin-2 muteins and polymer conjugation thereof |
| US4902502A (en) * | 1989-01-23 | 1990-02-20 | Cetus Corporation | Preparation of a polymer/interleukin-2 conjugate |
| US5225212A (en) | 1989-10-20 | 1993-07-06 | Liposome Technology, Inc. | Microreservoir liposome composition and method |
| AU661533B2 (en) * | 1992-01-20 | 1995-07-27 | Astrazeneca Ab | Quinazoline derivatives |
| GB9314893D0 (en) * | 1993-07-19 | 1993-09-01 | Zeneca Ltd | Quinazoline derivatives |
| IL112249A (en) * | 1994-01-25 | 2001-11-25 | Warner Lambert Co | Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds |
| US5654307A (en) * | 1994-01-25 | 1997-08-05 | Warner-Lambert Company | Bicyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family |
| IL112248A0 (en) * | 1994-01-25 | 1995-03-30 | Warner Lambert Co | Tricyclic heteroaromatic compounds and pharmaceutical compositions containing them |
| GB9508538D0 (en) * | 1995-04-27 | 1995-06-14 | Zeneca Ltd | Quinazoline derivatives |
| US5747498A (en) * | 1996-05-28 | 1998-05-05 | Pfizer Inc. | Alkynyl and azido-substituted 4-anilinoquinazolines |
| CA2230492C (en) | 1995-09-21 | 2009-05-26 | Genentech, Inc. | Human growth hormone variants |
| US6030945A (en) * | 1996-01-09 | 2000-02-29 | Genentech, Inc. | Apo-2 ligand |
| US5760041A (en) * | 1996-02-05 | 1998-06-02 | American Cyanamid Company | 4-aminoquinazoline EGFR Inhibitors |
| GB9603095D0 (en) * | 1996-02-14 | 1996-04-10 | Zeneca Ltd | Quinazoline derivatives |
| SK284073B6 (sk) * | 1996-04-12 | 2004-09-08 | Warner-Lambert Company | Polycyklické zlúčeniny, ich použitie a farmaceutické kompozície na ich báze |
| ATE227283T1 (de) * | 1996-07-13 | 2002-11-15 | Glaxo Group Ltd | Kondensierte heterozyklische verbindungen als protein kinase inhibitoren |
| US7452538B2 (en) * | 1997-01-28 | 2008-11-18 | Human Genome Sciences, Inc. | Death domain containing receptor 4 antibodies and methods |
| US6072047A (en) * | 1997-02-13 | 2000-06-06 | Immunex Corporation | Receptor that binds trail |
| US6002008A (en) * | 1997-04-03 | 1999-12-14 | American Cyanamid Company | Substituted 3-cyano quinolines |
| US6235883B1 (en) * | 1997-05-05 | 2001-05-22 | Abgenix, Inc. | Human monoclonal antibodies to epidermal growth factor receptor |
| US6342369B1 (en) * | 1997-05-15 | 2002-01-29 | Genentech, Inc. | Apo-2-receptor |
| ATE516354T1 (de) | 1997-05-15 | 2011-07-15 | Genentech Inc | Apo-2-rezeptor |
| US6252050B1 (en) * | 1998-06-12 | 2001-06-26 | Genentech, Inc. | Method for making monoclonal antibodies and cross-reactive antibodies obtainable by the method |
| JP3687900B2 (ja) * | 1998-11-19 | 2005-08-24 | ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー | チロシンキナーゼの不可逆的阻害剤であるn−[4−(3−クロロ−4−フルオロフェニルアミノ)−7−(3−モルホリン−4−イルプロポキシ)キナゾリン−6−イル]アクリルアミド |
| JP2005508162A (ja) * | 2001-10-02 | 2005-03-31 | ジェネンテック・インコーポレーテッド | Apo−2リガンド変異体とその使用法 |
| DK1450847T3 (da) * | 2001-11-13 | 2010-12-13 | Genentech Inc | Apo2-ligand/TRAIL-formuleringer og anvendelser deraf |
| RU2240125C2 (ru) * | 2002-11-12 | 2004-11-20 | Государственное учреждение Гематологический научный центр РАМН | СПОСОБ ЭФФЕКТИВНОЙ ИНДУКЦИИ АПОПТОЗА В СУСПЕНЗИОННЫХ КУЛЬТУРАХ ОПУХОЛЕВЫХ PH$$$ КЛЕТОК КОСТНОГО МОЗГА И ПЕРИФЕРИЧЕСКОЙ КРОВИ БОЛЬНЫХ Ph+ ЛЕЙКОЗАМИ С ПОМОЩЬЮ АНТИСЕНС ОЛИГОНУКЛЕОТИДОВ, СПЕЦИФИЧНЫХ К МРНК ГЕНОВ, ИНГИБИРУЮЩИХ АПОПТОЗ |
| US20040147428A1 (en) * | 2002-11-15 | 2004-07-29 | Pluenneke John D. | Methods of treatment using an inhibitor of epidermal growth factor receptor |
| PL1622929T3 (pl) * | 2003-05-09 | 2007-03-30 | Genentech Inc | Peptydy wiążące się z receptorem APO2L(TRAIL) oraz ich zastosowanie |
-
2005
- 2005-02-18 US US11/061,258 patent/US20060188498A1/en not_active Abandoned
-
2006
- 2006-02-16 BR BRPI0606360-8A patent/BRPI0606360A2/pt not_active Application Discontinuation
- 2006-02-16 ZA ZA200706859A patent/ZA200706859B/xx unknown
- 2006-02-16 CN CNA2006800125585A patent/CN101180072A/zh active Pending
- 2006-02-16 RU RU2007134568/10A patent/RU2429006C2/ru active
- 2006-02-16 WO PCT/US2006/005459 patent/WO2006089015A2/en not_active Ceased
- 2006-02-16 EP EP06735219.5A patent/EP1853300B1/en not_active Expired - Lifetime
- 2006-02-16 AU AU2006214292A patent/AU2006214292A1/en not_active Abandoned
- 2006-02-16 KR KR1020077018796A patent/KR20070110852A/ko not_active Ceased
- 2006-02-16 CA CA002595931A patent/CA2595931A1/en not_active Abandoned
- 2006-02-16 JP JP2007556287A patent/JP2008532937A/ja not_active Withdrawn
-
2007
- 2007-07-25 IL IL184827A patent/IL184827A0/en unknown
- 2007-09-17 NO NO20074740A patent/NO20074740L/no not_active Application Discontinuation
-
2012
- 2012-07-04 JP JP2012150088A patent/JP2012229237A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2012229237A (ja) | 2012-11-22 |
| CA2595931A1 (en) | 2006-08-24 |
| WO2006089015A3 (en) | 2007-08-23 |
| BRPI0606360A2 (pt) | 2009-06-23 |
| EP1853300A2 (en) | 2007-11-14 |
| AU2006214292A1 (en) | 2006-08-24 |
| EP1853300B1 (en) | 2014-07-23 |
| KR20070110852A (ko) | 2007-11-20 |
| IL184827A0 (en) | 2008-08-07 |
| CN101180072A (zh) | 2008-05-14 |
| JP2008532937A (ja) | 2008-08-21 |
| WO2006089015A2 (en) | 2006-08-24 |
| RU2007134568A (ru) | 2009-03-27 |
| RU2429006C2 (ru) | 2011-09-20 |
| US20060188498A1 (en) | 2006-08-24 |
| ZA200706859B (en) | 2008-11-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |