NO20074815L - Fremgangsmate for a identifisere PDE10-modulatorer - Google Patents

Fremgangsmate for a identifisere PDE10-modulatorer

Info

Publication number
NO20074815L
NO20074815L NO20074815A NO20074815A NO20074815L NO 20074815 L NO20074815 L NO 20074815L NO 20074815 A NO20074815 A NO 20074815A NO 20074815 A NO20074815 A NO 20074815A NO 20074815 L NO20074815 L NO 20074815L
Authority
NO
Norway
Prior art keywords
identifying
procedure
pde10
modulators
domain
Prior art date
Application number
NO20074815A
Other languages
English (en)
Inventor
Joachim Schultz
Jost Weber
Original Assignee
Nycomed Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Gmbh filed Critical Nycomed Gmbh
Publication of NO20074815L publication Critical patent/NO20074815L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Den foreliggende oppfinnelsen berører et nytt polypeptid som består av GAFA domenet og GAFB domenet tilhørende en fosfodiesterase 10 (PDE10) og det katalytiske domenet tilhørende en adenylat syklase, så vel som bruken av dette polypeptidet i en metode for å identifisere PDE10-modulatorer.
NO20074815A 2005-02-28 2007-09-21 Fremgangsmate for a identifisere PDE10-modulatorer NO20074815L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102005009773 2005-02-28
DE102005009849 2005-03-01
PCT/EP2005/052271 WO2006092174A1 (de) 2005-02-28 2005-05-18 Methode zur identifizierung von pde10-modulatoren

Publications (1)

Publication Number Publication Date
NO20074815L true NO20074815L (no) 2007-11-08

Family

ID=35064635

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20074815A NO20074815L (no) 2005-02-28 2007-09-21 Fremgangsmate for a identifisere PDE10-modulatorer

Country Status (8)

Country Link
EP (1) EP1856253A1 (no)
JP (1) JP2008531024A (no)
KR (1) KR20070116015A (no)
AU (1) AU2005328604A1 (no)
CA (1) CA2604349A1 (no)
IL (1) IL185086A0 (no)
NO (1) NO20074815L (no)
WO (1) WO2006092174A1 (no)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3307999A (en) * 1998-02-23 1999-09-06 Icos Corporation Phosphodiesterase 10

Also Published As

Publication number Publication date
KR20070116015A (ko) 2007-12-06
JP2008531024A (ja) 2008-08-14
CA2604349A1 (en) 2006-09-08
IL185086A0 (en) 2007-12-03
WO2006092174A1 (de) 2006-09-08
AU2005328604A1 (en) 2006-09-08
EP1856253A1 (de) 2007-11-21

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Legal Events

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Representative=s name: PLOUGMANN & VINGTOFT, POSTBOKS 1003 SENTRUM, 0104

FC2A Withdrawal, rejection or dismissal of laid open patent application