NO20082880L - Inhibitorer av C-MET samt anvendelse derav - Google Patents

Inhibitorer av C-MET samt anvendelse derav

Info

Publication number
NO20082880L
NO20082880L NO20082880A NO20082880A NO20082880L NO 20082880 L NO20082880 L NO 20082880L NO 20082880 A NO20082880 A NO 20082880A NO 20082880 A NO20082880 A NO 20082880A NO 20082880 L NO20082880 L NO 20082880L
Authority
NO
Norway
Prior art keywords
inhibitors
met
provides
compounds
utilizing
Prior art date
Application number
NO20082880A
Other languages
English (en)
Inventor
Jon Come
Alexander Aronov
David Lauffer
Pan Li
David DEININGER
Kira Mcginty
Dean Stamos
Michelle Stewart
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of NO20082880L publication Critical patent/NO20082880L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433—Thidiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Den foreliggende oppfinnelsen fremskaffer forbindelser som er nyttige som hemmere av c-Met tyrosinkinase. Oppfinnelsen fremskaffer også farmasøytisk akseptable blandinger som inneholder oppfinnelsens forbindelser og metoder til å benytte blandingene til behandling av forskjellige proliferative forstyrrelser.
NO20082880A 2005-11-30 2008-06-30 Inhibitorer av C-MET samt anvendelse derav NO20082880L (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US74074105P 2005-11-30 2005-11-30
US74085905P 2005-11-30 2005-11-30
US74073705P 2005-11-30 2005-11-30
PCT/US2006/045847 WO2007064797A2 (en) 2005-11-30 2006-11-30 Inhibitors of c-met and uses thereof

Publications (1)

Publication Number Publication Date
NO20082880L true NO20082880L (no) 2008-09-01

Family

ID=37998312

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20082880A NO20082880L (no) 2005-11-30 2008-06-30 Inhibitorer av C-MET samt anvendelse derav

Country Status (12)

Country Link
US (2) US7728017B2 (no)
EP (1) EP1963329B1 (no)
JP (1) JP5144532B2 (no)
KR (1) KR20080080584A (no)
AU (1) AU2006320580B2 (no)
BR (1) BRPI0619252A2 (no)
CA (1) CA2630884A1 (no)
IL (1) IL191623A0 (no)
MX (1) MX2008007049A (no)
NO (1) NO20082880L (no)
NZ (1) NZ568666A (no)
WO (1) WO2007064797A2 (no)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO340958B1 (no) * 2005-12-21 2017-07-31 Janssen Pharmaceutica Nv Triazolopyridaziner som tyrosinkinase modulatorer

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DE10038019A1 (de) 2000-08-04 2002-02-14 Bayer Ag Substituierte Triazolopyrid(az)ine
US7122548B2 (en) * 2003-07-02 2006-10-17 Sugen, Inc. Triazolotriazine compounds and uses thereof
HUE030390T2 (en) * 2005-12-21 2017-05-29 Janssen Pharmaceutica Nv Triazolopyridazines as tyrosine kinase modulators

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NO340958B1 (no) * 2005-12-21 2017-07-31 Janssen Pharmaceutica Nv Triazolopyridaziner som tyrosinkinase modulatorer

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US7998987B2 (en) 2011-08-16
BRPI0619252A2 (pt) 2011-09-20
KR20080080584A (ko) 2008-09-04
AU2006320580B2 (en) 2011-06-23
JP2009518296A (ja) 2009-05-07
US20100190774A1 (en) 2010-07-29
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US7728017B2 (en) 2010-06-01
CA2630884A1 (en) 2007-06-07
IL191623A0 (en) 2008-12-29
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US20070191369A1 (en) 2007-08-16

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