NO20076054L - Imidiazo - og triazolopyridiner som inhibitorer av 11-beta-hydroksysteroid-dehydrogenase type I - Google Patents

Imidiazo - og triazolopyridiner som inhibitorer av 11-beta-hydroksysteroid-dehydrogenase type I

Info

Publication number
NO20076054L
NO20076054L NO20076054A NO20076054A NO20076054L NO 20076054 L NO20076054 L NO 20076054L NO 20076054 A NO20076054 A NO 20076054A NO 20076054 A NO20076054 A NO 20076054A NO 20076054 L NO20076054 L NO 20076054L
Authority
NO
Norway
Prior art keywords
beta
hydroxysteroid dehydrogenase
inhibitors
dehydrogenase type
imidiazo
Prior art date
Application number
NO20076054A
Other languages
English (en)
Inventor
James J Li
Lawrence G Hamann
Haixia Wang
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of NO20076054L publication Critical patent/NO20076054L/no

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
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    • A61P9/12—Antihypertensives

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  • Organic Chemistry (AREA)
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Abstract

Det er tilveiebrakt nye forbindelser som er inhibitorer av 11-beta-hydroksysteroid-dehydrogenase type I. Inhibitorer av 11-beta-hydroksysteroid-dehydrogenase type I er anvendelige for behandling av, forebygging av eller reduksjon av progresjonshastigheten til sykdommer som krever terapi med 11-beta-hydroksysteroid-dehydrogenase type I-inhibitor. Disse nye forbindelsene har strukturen: W-L-Z (I) eller stereoisomerer, prodrugs eller farmasøytisk akseptable salter derav, hvor W, L og Z er som definert her.
NO20076054A 2005-06-09 2007-11-26 Imidiazo - og triazolopyridiner som inhibitorer av 11-beta-hydroksysteroid-dehydrogenase type I NO20076054L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US68899305P 2005-06-09 2005-06-09
US11/448,946 US7572807B2 (en) 2005-06-09 2006-06-07 Heteroaryl 11-beta-hydroxysteroid dehydrogenase type I inhibitors
PCT/US2006/022260 WO2006135667A1 (en) 2005-06-09 2006-06-08 Imidiazo -and triazolopyridines as inhibitors of 11-beta hydroxysteroid dehydrogenase type i

Publications (1)

Publication Number Publication Date
NO20076054L true NO20076054L (no) 2008-03-04

Family

ID=37524860

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20076054A NO20076054L (no) 2005-06-09 2007-11-26 Imidiazo - og triazolopyridiner som inhibitorer av 11-beta-hydroksysteroid-dehydrogenase type I

Country Status (12)

Country Link
US (2) US7572807B2 (no)
EP (1) EP1912986B1 (no)
JP (1) JP5124450B2 (no)
KR (1) KR20080018942A (no)
AR (1) AR057357A1 (no)
AU (1) AU2006258077B2 (no)
ES (1) ES2392656T3 (no)
MX (1) MX2007015283A (no)
NO (1) NO20076054L (no)
PE (1) PE20070002A1 (no)
TW (1) TW200716116A (no)
WO (1) WO2006135667A1 (no)

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