NO20076219L - Farmasoytisk formulering med apomorfin for bukkal administrering - Google Patents

Farmasoytisk formulering med apomorfin for bukkal administrering

Info

Publication number
NO20076219L
NO20076219L NO20076219A NO20076219A NO20076219L NO 20076219 L NO20076219 L NO 20076219L NO 20076219 A NO20076219 A NO 20076219A NO 20076219 A NO20076219 A NO 20076219A NO 20076219 L NO20076219 L NO 20076219L
Authority
NO
Norway
Prior art keywords
apomorphine
buccal administration
pharmaceutical formulation
formulation
pharmaceutically acceptable
Prior art date
Application number
NO20076219A
Other languages
English (en)
Other versions
NO339404B1 (no
Inventor
Anthony Clarke
Original Assignee
Amarin Pharmaceuticals Ireland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amarin Pharmaceuticals Ireland filed Critical Amarin Pharmaceuticals Ireland
Publication of NO20076219L publication Critical patent/NO20076219L/no
Publication of NO339404B1 publication Critical patent/NO339404B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Psychology (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Den foreliggende oppfinnelse tilveiebringer et sett som omfatter, i separate avdelinger i en beholder, følgende komponenter (a) og (b): (a) en kombinasjon av apomorfin eller et farmasøytisk akseptabelt syreaddisjonssalt derav og en farmasøytisk akseptabel eksipient eller bærer; og (b) en løsning som omfatter et fortynningsmiddel og et pH-modifiserende middel; hvor komponentene er presentert slik at de kan kombineres på tidspunktet for anvendelse til en formulering som er justert til en pH som varierer fra svakt sur til alkalisk og som er egnet for bukal administrering. Formuleringen er nyttig til å behandle Parkinsons sykdom og til å fremme seksuell fiinksjon.
NO20076219A 2005-05-06 2007-12-03 Farmasøytisk formulering med apomorfin for bukkal administrering NO339404B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0509317.4A GB0509317D0 (en) 2005-05-06 2005-05-06 Pharmaceutical formulation of apomorphine
PCT/GB2006/001665 WO2006120412A1 (en) 2005-05-06 2006-05-08 Pharmaceutical formulation of apomorphine for buccal administration

Publications (2)

Publication Number Publication Date
NO20076219L true NO20076219L (no) 2007-12-03
NO339404B1 NO339404B1 (no) 2016-12-12

Family

ID=34685218

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20076219A NO339404B1 (no) 2005-05-06 2007-12-03 Farmasøytisk formulering med apomorfin for bukkal administrering

Country Status (20)

Country Link
US (2) US20090023766A1 (no)
EP (1) EP1885333B1 (no)
JP (1) JP5116665B2 (no)
KR (1) KR101365458B1 (no)
CN (1) CN101217936A (no)
AT (1) ATE545407T1 (no)
AU (1) AU2006245564A1 (no)
BR (1) BRPI0611258A2 (no)
CA (1) CA2607802C (no)
DK (1) DK1885333T3 (no)
ES (1) ES2383433T3 (no)
GB (1) GB0509317D0 (no)
IL (1) IL187183A0 (no)
MX (1) MX2007013890A (no)
NO (1) NO339404B1 (no)
PT (1) PT1885333E (no)
RU (1) RU2007140701A (no)
SI (1) SI1885333T1 (no)
WO (1) WO2006120412A1 (no)
ZA (1) ZA200709474B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0819530D0 (en) * 2008-10-24 2008-12-03 Univ Sheffield Methods and compositions
ES2699077T3 (es) * 2009-06-12 2019-02-07 Sunovion Pharmaceuticals Inc Apomorfina sublingual
PT2651357T (pt) * 2010-12-16 2020-06-17 Sunovion Pharmaceuticals Inc Películas sublinguais
EP2545788A1 (de) * 2011-07-13 2013-01-16 Martin Hulliger Diätisches Mehrkomponentensystem
WO2013181331A2 (en) * 2012-05-30 2013-12-05 Ibh Ventures, Llc Polyphenol-reactive oxygen species compositions and methods
NZ703341A (en) 2012-06-05 2016-11-25 Neuroderm Ltd Compositions comprising apomorphine and organic acids and uses thereof
KR20160108828A (ko) 2013-11-11 2016-09-20 임팩스 라보라토리즈, 인코포레이티드 신속하게 붕괴되는 제형 및 사용 방법
JP6042794B2 (ja) * 2013-12-03 2016-12-14 本田技研工業株式会社 車両制御方法
EP3177270A4 (en) * 2014-08-07 2018-01-24 Mucodel Pharma LLC Chemically stable and oromucosally absorbable gel compositions of a pharmaceutical active agent in a multi-chambered delivery system
US10493027B2 (en) 2014-08-07 2019-12-03 Mucodel Pharma Llc Chemically stable compositions of a pharmaceutical active agent in a multi- chambered delivery system for mucosal delivery
EP4578461A3 (en) 2015-04-21 2025-09-03 Sumitomo Pharma America, Inc. Methods of treating parkinsons disease by administration of apomorphine to an oral mucosa
US20180280465A1 (en) 2015-09-28 2018-10-04 Ever Neuro Pharma Gmbh Aqueous composition of apomorphine for subcutaneous administration
WO2018148382A1 (en) * 2017-02-10 2018-08-16 Mucodel Pharma Llc Chemically stable compositions of a pharmaceutical active agent in a multi-chambered delivery system for mucosal delivery
GB201912686D0 (en) * 2019-09-04 2019-10-16 Reown Pharma Inc Pharmaceutical composition
US20240335379A1 (en) * 2021-08-05 2024-10-10 Zydus Lifesciences Limited Stable pharmaceutical compositions of apomorphine
KR20250023394A (ko) 2022-06-15 2025-02-18 에버 뉴로 파르마 게엠베하 아포모르핀 전구약물 및 이의 용도
WO2025259725A1 (en) * 2024-06-11 2025-12-18 Nano Pharmasolutions, Inc. Apomorphine compositions and therapeutic applications

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE290864T1 (de) * 1993-03-26 2005-04-15 Franciscus Wilhelmus He Merkus Pharmazeutische zusammensetzungen zur intranasalen verabreichung von dihydroergotamin
US6121276A (en) * 1994-04-22 2000-09-19 Pentech Pharmaceuticals, Inc. Apomorphine-containing dosage forms for ameliorating male erectile dysfunction
GB9517062D0 (en) * 1995-08-18 1995-10-25 Scherer Ltd R P Pharmaceutical compositions
WO1998048784A2 (en) * 1997-04-28 1998-11-05 The University Of British Columbia Method and composition for modulating amyloidosis
US6436950B1 (en) * 1998-08-14 2002-08-20 Nastech Pharmaceutical Company, Inc. Nasal delivery of apomorphine
CN1414853A (zh) * 1999-12-30 2003-04-30 塔普控股公司 阿朴吗啡的口腔粘膜剂型
AU2001269516B2 (en) * 2000-07-13 2006-09-14 Takeda Pharmaceutical Company Limited Lipid-rich plaque regressing agents
US20040028613A1 (en) * 2001-06-25 2004-02-12 Nastech Pharmaceutical Company Inc Dopamine agonist formulations for enhanced central nervous system delivery
US20030068356A1 (en) * 2001-07-10 2003-04-10 Pather S. Indiran Sequential drug delivery systems
JP2005537244A (ja) * 2002-06-28 2005-12-08 ナステック・ファーマシューティカル・カンパニー・インコーポレーテッド 療法化合物の粘膜搬送を増進させるための、上皮接合部接着分子の生理機能を調節する組成物および方法
SE0202365D0 (sv) * 2002-08-05 2002-08-05 Pharmacia Ab New formulation and use thereof
US20040126448A1 (en) * 2002-08-05 2004-07-01 Nils-Olof Lindberg Sexual dysfunction compounds
GB0403938D0 (en) * 2004-02-21 2004-03-24 West Pharm Serv Drug Res Ltd Chitosan containing solution

Also Published As

Publication number Publication date
PT1885333E (pt) 2012-05-14
CA2607802C (en) 2015-02-10
SI1885333T1 (sl) 2012-07-31
CA2607802A1 (en) 2006-11-16
GB0509317D0 (en) 2005-06-15
DK1885333T3 (da) 2012-05-14
WO2006120412A1 (en) 2006-11-16
IL187183A0 (en) 2008-02-09
BRPI0611258A2 (pt) 2010-11-23
JP2008540392A (ja) 2008-11-20
KR20080016608A (ko) 2008-02-21
US8772309B2 (en) 2014-07-08
ATE545407T1 (de) 2012-03-15
US20090023766A1 (en) 2009-01-22
US20130131098A1 (en) 2013-05-23
KR101365458B1 (ko) 2014-02-19
ES2383433T3 (es) 2012-06-21
EP1885333B1 (en) 2012-02-15
HK1113086A1 (en) 2008-09-26
RU2007140701A (ru) 2009-06-20
AU2006245564A1 (en) 2006-11-16
CN101217936A (zh) 2008-07-09
ZA200709474B (en) 2008-12-31
EP1885333A1 (en) 2008-02-13
MX2007013890A (es) 2008-04-04
JP5116665B2 (ja) 2013-01-09
NO339404B1 (no) 2016-12-12

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