NO20080823L - Fremgangsmate for fremstilling av nebivolol - Google Patents

Fremgangsmate for fremstilling av nebivolol

Info

Publication number
NO20080823L
NO20080823L NO20080823A NO20080823A NO20080823L NO 20080823 L NO20080823 L NO 20080823L NO 20080823 A NO20080823 A NO 20080823A NO 20080823 A NO20080823 A NO 20080823A NO 20080823 L NO20080823 L NO 20080823L
Authority
NO
Norway
Prior art keywords
nebivolol
preparation
separated
transphonation
cyanhydrins
Prior art date
Application number
NO20080823A
Other languages
English (en)
Norwegian (no)
Inventor
Christian N Noe
Muhammed Jasic
Hermann Kollmann
Bodo Lachmann
Original Assignee
Pharmacon Forschung & Beratung Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacon Forschung & Beratung Gmbh filed Critical Pharmacon Forschung & Beratung Gmbh
Publication of NO20080823L publication Critical patent/NO20080823L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
NO20080823A 2005-07-19 2008-02-15 Fremgangsmate for fremstilling av nebivolol NO20080823L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0121405A AT502220A1 (de) 2005-07-19 2005-07-19 Verfahren zur herstellung von nebivolol
PCT/AT2006/000303 WO2007009143A2 (de) 2005-07-19 2006-07-17 Verfahren zur herstellung nebivolol

Publications (1)

Publication Number Publication Date
NO20080823L true NO20080823L (no) 2008-04-02

Family

ID=37450808

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20080823A NO20080823L (no) 2005-07-19 2008-02-15 Fremgangsmate for fremstilling av nebivolol

Country Status (15)

Country Link
US (1) US20080221340A1 (de)
EP (1) EP1919888A2 (de)
JP (1) JP2009502750A (de)
KR (1) KR20080027368A (de)
CN (1) CN101243062A (de)
AT (1) AT502220A1 (de)
AU (1) AU2006272420A1 (de)
BR (1) BRPI0613610A2 (de)
CA (1) CA2615832A1 (de)
EA (1) EA200800364A1 (de)
IL (1) IL188777A0 (de)
MX (1) MX2008000747A (de)
NO (1) NO20080823L (de)
WO (1) WO2007009143A2 (de)
ZA (1) ZA200800963B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE533752T1 (de) 2008-09-08 2011-12-15 Cadila Pharmaceuticals Ltd Verbesserter herstellungsprozess für nebivolol- hydrocholorid
IT1395354B1 (it) * 2009-07-23 2012-09-14 Zach System Spa Processo di preparazione di nebivololo
DE102010005953A1 (de) 2010-01-27 2011-07-28 Corden PharmaChem GmbH, 68305 Verfahren zur Herstellung von Nebivolol
IT1397962B1 (it) * 2010-02-11 2013-02-04 Menarini Int Operations Lu Sa Processo per la preparazione del nebivololo.
CN102190647A (zh) * 2010-03-12 2011-09-21 浙江海翔药业股份有限公司 一种奈比洛尔的中间体的制备方法
CN107531662B (zh) 2015-05-19 2021-08-06 浙江奥翔药业股份有限公司 奈必洛尔的合成方法及其中间体化合物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1337429C (en) * 1983-12-05 1995-10-24 Guy Rosalia Eugene Van Lommen Derivatives of 2,2'-iminobisethanol
CN100546987C (zh) * 2005-03-03 2009-10-07 浙江医药股份有限公司新昌制药厂 Dl-奈必洛尔及其盐酸盐的制备方法

Also Published As

Publication number Publication date
WO2007009143A3 (de) 2007-04-05
CA2615832A1 (en) 2007-01-25
IL188777A0 (en) 2008-08-07
CN101243062A (zh) 2008-08-13
EP1919888A2 (de) 2008-05-14
ZA200800963B (en) 2009-08-26
AT502220A1 (de) 2007-02-15
KR20080027368A (ko) 2008-03-26
US20080221340A1 (en) 2008-09-11
BRPI0613610A2 (pt) 2011-01-18
JP2009502750A (ja) 2009-01-29
EA200800364A1 (ru) 2008-06-30
MX2008000747A (es) 2008-04-14
AU2006272420A1 (en) 2007-01-25
WO2007009143A2 (de) 2007-01-25

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application