NO20081220L - Nytt cercosporamidderivat - Google Patents
Nytt cercosporamidderivatInfo
- Publication number
- NO20081220L NO20081220L NO20081220A NO20081220A NO20081220L NO 20081220 L NO20081220 L NO 20081220L NO 20081220 A NO20081220 A NO 20081220A NO 20081220 A NO20081220 A NO 20081220A NO 20081220 L NO20081220 L NO 20081220L
- Authority
- NO
- Norway
- Prior art keywords
- group
- alkyl group
- halogenated
- hydrogen atom
- cercosporamide derivative
- Prior art date
Links
- GEWLYFZWVLXQME-MRXNPFEDSA-N cercosporamide Chemical class O=C([C@]12C)C(C(=O)C)=C(O)C=C1OC1=C2C(O)=CC(O)=C1C(N)=O GEWLYFZWVLXQME-MRXNPFEDSA-N 0.000 title abstract 3
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 6
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- 125000006766 (C2-C6) alkynyloxy group Chemical group 0.000 abstract 1
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 abstract 1
- 125000003320 C2-C6 alkenyloxy group Chemical group 0.000 abstract 1
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 abstract 1
- 125000000041 C6-C10 aryl group Chemical group 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 230000002218 hypoglycaemic effect Effects 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 229940043274 prophylactic drug Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229940126585 therapeutic drug Drugs 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/91—Dibenzofurans; Hydrogenated dibenzofurans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Oppfinnelsen vedrører et nytt cercosporamidderivat som har en god hypoglykemisk effekt og er anvendbart til et terapeutisk legemiddel og/eller profylaktisk legemiddel for sukkersyke, et farmakologisk akseptabelt salt derav eller en ester derav. Cercosporamid-derivatet har den generelle formel (I): hvor X er et oksygenatom eller lignende; R1 er et hydrogenatom eller en C1-C6-alkylgruppe; R2 er et hydrogenatom, en C1-C6-alkylgruppe eller en halogenert C1-C6-alkylgruppe; R3 er et hydrogenatom eller en C1-C6-alkylgruppe; R4 er en C6-C10-arylgruppe som kan være substituert med 1-5 grupper uavhengig valgt fra substituentgruppe (a) eller lignende; n er 1, 2 eller 3; og substituentgruppen (a) er et halogenatom, en C1-C6-alkylgruppe, en halogenert C1-C6-alkylgruppe, en C2-C6-alkenylgruppe, en C2-C6-alkynylgruppe, en C1-C6-alkoksy-gruppe, en halogenert C1-C6-alkoksy-gruppe, en C2_C6-alkenyloksygruppe, en C2-C6-alkynyloksygruppe og lignende.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005230558 | 2005-08-09 | ||
| JP2005379060 | 2005-12-28 | ||
| PCT/JP2006/315621 WO2007018193A1 (ja) | 2005-08-09 | 2006-08-08 | 新規セルコスポラミド誘導体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20081220L true NO20081220L (no) | 2008-05-08 |
Family
ID=37727376
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20081220A NO20081220L (no) | 2005-08-09 | 2008-03-07 | Nytt cercosporamidderivat |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20090036492A1 (no) |
| EP (1) | EP1914229B1 (no) |
| JP (1) | JP4085129B2 (no) |
| KR (1) | KR20080033367A (no) |
| AU (1) | AU2006277289A1 (no) |
| CA (1) | CA2618622A1 (no) |
| DE (1) | DE602006014973D1 (no) |
| IL (1) | IL189172A0 (no) |
| NO (1) | NO20081220L (no) |
| RU (1) | RU2008108997A (no) |
| TW (1) | TW200740786A (no) |
| WO (1) | WO2007018193A1 (no) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2618631A1 (en) * | 2005-08-09 | 2007-02-15 | Daiichi Sankyo Company, Limited | Method for producing cercosporamide |
| WO2008096769A1 (ja) * | 2007-02-08 | 2008-08-14 | Daiichi Sankyo Company, Limited | 置換されたセルコスポラミド誘導体を含有する医薬 |
| PL216649B1 (pl) | 2011-06-06 | 2014-04-30 | Univ Warszawski | Nowe kompleksy rutenu, sposób ich wytwarzania oraz zastosowanie w reakcji metatezy olefin |
| CN103755827B (zh) * | 2014-01-16 | 2015-12-09 | 合肥工业大学 | 粒毛盘菌胞外多糖羧甲基化衍生物及其制抗肾衰药的用途 |
| WO2016074696A1 (en) * | 2014-11-10 | 2016-05-19 | Givaudan Ag | Perfume ingredients and perfume preparations containing same |
| JP2019510061A (ja) * | 2016-03-31 | 2019-04-11 | サウス オーストラリアン ヘルス アンド メディカル リサーチ インスティテュート リミテッドＳｏｕｔｈ Ａｕｓｔｒａｌｉａｎ Ｈｅａｌｔｈ Ａｎｄ Ｍｅｄｉｃａｌ Ｒｅｓｅａｒｃｈ Ｉｎｓｔｉｔｕｔｅ Ｌｉｍｉｔｅｄ | 高脂肪食関連疾患を阻害する方法 |
| JP7091958B2 (ja) * | 2018-09-11 | 2022-06-28 | 株式会社デンソー | 射出成形品の製造方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3825840A1 (de) * | 1988-07-29 | 1990-02-01 | Basf Ag | Dihydrodibenzofuranderivate und diese verbindungen enthaltende fungizide |
| CA2471620A1 (en) * | 2001-12-31 | 2003-07-24 | Actelion Pharmaceuticals Ltd | Pyrrolidone carboxamides |
-
2006
- 2006-08-08 WO PCT/JP2006/315621 patent/WO2007018193A1/ja not_active Ceased
- 2006-08-08 AU AU2006277289A patent/AU2006277289A1/en not_active Abandoned
- 2006-08-08 TW TW095128965A patent/TW200740786A/zh unknown
- 2006-08-08 JP JP2007529584A patent/JP4085129B2/ja not_active Expired - Fee Related
- 2006-08-08 DE DE602006014973T patent/DE602006014973D1/de active Active
- 2006-08-08 CA CA002618622A patent/CA2618622A1/en not_active Abandoned
- 2006-08-08 RU RU2008108997/04A patent/RU2008108997A/ru unknown
- 2006-08-08 KR KR1020087003087A patent/KR20080033367A/ko not_active Withdrawn
- 2006-08-08 EP EP06796306A patent/EP1914229B1/en not_active Not-in-force
- 2006-08-08 US US11/990,289 patent/US20090036492A1/en not_active Abandoned
-
2008
- 2008-02-03 IL IL189172A patent/IL189172A0/en unknown
- 2008-03-07 NO NO20081220A patent/NO20081220L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1914229A1 (en) | 2008-04-23 |
| WO2007018193A1 (ja) | 2007-02-15 |
| CA2618622A1 (en) | 2007-02-15 |
| EP1914229B1 (en) | 2010-06-16 |
| KR20080033367A (ko) | 2008-04-16 |
| IL189172A0 (en) | 2008-06-05 |
| EP1914229A4 (en) | 2009-03-18 |
| TW200740786A (en) | 2007-11-01 |
| JP4085129B2 (ja) | 2008-05-14 |
| AU2006277289A1 (en) | 2007-02-15 |
| JPWO2007018193A1 (ja) | 2009-02-19 |
| US20090036492A1 (en) | 2009-02-05 |
| DE602006014973D1 (de) | 2010-07-29 |
| RU2008108997A (ru) | 2009-09-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |