NO20081690L - Tumorassosierte peptider som bindes til humant leukocyttantigen (HLA) klasse I- eller II-molekyler og relatert vaksine mot kreft - Google Patents
Tumorassosierte peptider som bindes til humant leukocyttantigen (HLA) klasse I- eller II-molekyler og relatert vaksine mot kreftInfo
- Publication number
- NO20081690L NO20081690L NO20081690A NO20081690A NO20081690L NO 20081690 L NO20081690 L NO 20081690L NO 20081690 A NO20081690 A NO 20081690A NO 20081690 A NO20081690 A NO 20081690A NO 20081690 L NO20081690 L NO 20081690L
- Authority
- NO
- Norway
- Prior art keywords
- molecules
- tumour
- present
- relates
- hla
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 229960005486 vaccine Drugs 0.000 title abstract 3
- 201000011510 cancer Diseases 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 210000000265 leukocyte Anatomy 0.000 title 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 2
- 230000028993 immune response Effects 0.000 abstract 2
- 230000001024 immunotherapeutic effect Effects 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000008186 active pharmaceutical agent Substances 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 210000002443 helper t lymphocyte Anatomy 0.000 abstract 1
- 238000009169 immunotherapy Methods 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Denne oppfinnelsen er relatert til immunoterapeutiske metoder og molekyler og celler for bruk innen immunterapeutiske metoder. Oppfinnelsen er spesielt relatert til immunoterapi av kreft. Videre er denne oppfinnelsen relatert til tumorassosierte T-hjelpecelle-peptidepitoper, alene eller i kombinasjon med andre tumorassosierte peptider som fungerer som aktive farmasøytiske bestanddeler i vaksinesammensetninger som stimulerer anti-tumor immunrespons. Oppfinnelsen er spesielt relatert til to nye peptidsekvenser derivert fra HLA klasse II molekyler fra humane kreftcellelinjer som kan brukes i vaksinesammensetninger for å frambringe antitumor immunrespons.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05019255A EP1760089B1 (en) | 2005-09-05 | 2005-09-05 | Tumor-associated peptides binding to human leukocyte antigen (HLA) class I or II molecules and related anti-cancer vaccine |
| PCT/EP2006/008641 WO2007028573A1 (en) | 2005-09-05 | 2006-09-05 | Tumor-associated peptides binding to human leukocyte antigen (hla) class i or ii molecules and related anti-cancer vaccine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20081690L true NO20081690L (no) | 2008-04-04 |
Family
ID=35149455
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20081690A NO20081690L (no) | 2005-09-05 | 2008-04-04 | Tumorassosierte peptider som bindes til humant leukocyttantigen (HLA) klasse I- eller II-molekyler og relatert vaksine mot kreft |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US20090274714A1 (no) |
| EP (2) | EP1760089B1 (no) |
| JP (1) | JP5132561B2 (no) |
| KR (1) | KR101150663B1 (no) |
| CN (1) | CN101287755B (no) |
| AT (2) | ATE440107T1 (no) |
| AU (1) | AU2006289289B2 (no) |
| BR (1) | BRPI0615466A2 (no) |
| CA (1) | CA2621414C (no) |
| CY (2) | CY1110536T1 (no) |
| DE (2) | DE602005016112D1 (no) |
| DK (2) | DK1760089T3 (no) |
| EA (1) | EA013466B1 (no) |
| ES (2) | ES2330013T3 (no) |
| HR (1) | HRP20110240T1 (no) |
| NO (1) | NO20081690L (no) |
| NZ (1) | NZ565956A (no) |
| PL (2) | PL1760089T3 (no) |
| PT (2) | PT1760089E (no) |
| RS (1) | RS51893B (no) |
| SI (2) | SI1760089T1 (no) |
| UA (2) | UA105210C2 (no) |
| WO (1) | WO2007028573A1 (no) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1806358B1 (en) | 2005-09-05 | 2010-03-17 | Immatics Biotechnologies GmbH | Tumor-associated peptides binding promiscuously to human leukocyte antigen (HLA) class II molecules |
| US20090004213A1 (en) | 2007-03-26 | 2009-01-01 | Immatics Biotechnologies Gmbh | Combination therapy using active immunotherapy |
| ES2321680B1 (es) * | 2007-04-26 | 2010-03-05 | Fundacion Para La Investigacion Biosanitaria De Andalucia Oriental - Alejandro Otero (Fibao) | Restauracion de las moleculas hla de clase i mediante terapia genica empleando vectores adenovirales portando el gen de la beta 2-microglobulina. |
| DK2183361T3 (en) | 2007-07-27 | 2015-07-27 | Immatics Biotechnologies Gmbh | Novel immunotherapy against brain tumors |
| BRPI0813626A2 (pt) | 2007-07-27 | 2014-12-23 | Immatics Biotechnologies Gmbh | Epitopos imunogênicos para a imunoterapia |
| BRPI0814140A2 (pt) * | 2007-07-27 | 2017-03-28 | Immatics Biotechnologies Gmbh | composição de peptídeos associados a tumor e vacina anticâncer relacionada |
| CY1112212T1 (el) * | 2008-04-24 | 2015-12-09 | Immatics Biotechnologies Gmbh | Νεα σκευασματα πεπτιδιων που σχετιζονται με ογκους τα οποια συνδεονται σε μορια του αντιγονου ανθρωπινων λευκοκυτταρων (hla) ταξης i ή ii για εμβολια |
| DE602008000891D1 (de) | 2008-04-30 | 2010-05-12 | Immatics Biotechnologies Gmbh | Neuartige Formulierungen von Tumor-assoziierten Peptiden, welche an menschliche Leukozytenantigene der Klasse I oder II für Impfungen binden |
| RS53872B2 (sr) * | 2008-05-14 | 2018-06-29 | Immatics Biotechnologies Gmbh | Novi i snažni mhc peptidi klase ii izvedeni iz survivina i neurokana |
| AU2016204710B2 (en) * | 2008-10-01 | 2018-02-22 | Immatics Biotechnologies Gmbh | Novel immunotherapy against several tumors including neuronal and brain tumors |
| RS53782B1 (sr) * | 2008-10-01 | 2015-06-30 | Immatics Biotechnologies Gmbh | Preparati tumor-asociranih peptida i odgovarajuća antikancerska vakcina za tretman glioblastoma (gbm) i drugih kancera |
| GB201004551D0 (en) * | 2010-03-19 | 2010-05-05 | Immatics Biotechnologies Gmbh | NOvel immunotherapy against several tumors including gastrointestinal and gastric cancer |
| GB201004575D0 (en) * | 2010-03-19 | 2010-05-05 | Immatics Biotechnologies Gmbh | Composition of tumor associated peptides and related anti cancer vaccine for the treatment of gastric cancer and other cancers |
| GB201006360D0 (en) * | 2010-04-16 | 2010-06-02 | Immatics Biotechnologies Gmbh | Method for differentially quantifying naturally processed HLA-restricted peptides for cancer, autoimmune and infectious diseases immunotherapy development |
| GB201009222D0 (en) | 2010-06-02 | 2010-07-21 | Immatics Biotechnologies Gmbh | Improved cancer therapy based on tumour associated antigens derived from cyclin D1 |
| WO2012073459A1 (en) * | 2010-12-02 | 2012-06-07 | Oncotherapy Science, Inc. | Tomm34 peptides and vaccines including the same |
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| MY170949A (en) * | 2011-07-11 | 2019-09-20 | Cancer Res Initiatives Foundation | A peptide capable of binding with a human leukocyte antigen (hla) molecule, a cancer vaccine derived from said peptide and use of said cancer vaccine |
| CA2877933A1 (en) * | 2012-06-27 | 2014-01-03 | Yuri Bushkin | Rapid assays for t-cell activation by rna measurements using flow cytometry |
| US20140017267A1 (en) * | 2012-07-13 | 2014-01-16 | Matthias W Rath | Metalloproteinase oligopeptides and their therapeutic use |
| TWI777194B (zh) * | 2013-08-05 | 2022-09-11 | 德商伊瑪提克斯生物科技有限公司 | 新穎肽類,細胞及其用於治療多種腫瘤的用途,其製造方法及包含其等之醫藥組成物(一) |
| PT3079715T (pt) | 2013-12-09 | 2018-08-02 | Targovax Asa | Uma mistura de péptidos |
| GB201501017D0 (en) * | 2014-12-23 | 2015-03-04 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers |
| PL3545965T3 (pl) | 2014-12-23 | 2021-12-27 | Immatics Biotechnologies Gmbh | Nowe peptydy i kombinacja peptydów do stosowania w immunoterapii względem raka komórek wątroby (hcc) i innych rodzajów raka |
| AU2016232280B2 (en) * | 2015-03-16 | 2018-05-31 | Helmholtz Zentrum München-Deutsches Forschungszentrum Für Gesundheit Und Umwelt (Gmbh) | Method of detecting new immunogenic T cell epitopes and isolating new antigen-specific T cell receptors by means of an MHC cell library |
| GB201504502D0 (en) * | 2015-03-17 | 2015-04-29 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against pancreatic cancer and other cancers |
| MY190083A (en) | 2015-03-17 | 2022-03-25 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against pancreatic cancer and other cancers |
| FI3273986T3 (fi) | 2015-03-27 | 2024-02-07 | Immatics Biotechnologies Gmbh | Uusia peptidejä ja peptidien yhdistelmiä käytettäväksi immunoterapiassa eri syöpiä vastaan |
| GB201505305D0 (en) | 2015-03-27 | 2015-05-13 | Immatics Biotechnologies Gmbh | Novel Peptides and combination of peptides for use in immunotherapy against various tumors |
| GB201505585D0 (en) * | 2015-03-31 | 2015-05-13 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carinoma (RCC) and other cancers |
| GB201507030D0 (en) * | 2015-04-24 | 2015-06-10 | Immatics Biotechnologies Gmbh | Immunotherapy against lung cancers, in particular NSCLC |
| CA2989483A1 (en) * | 2015-06-19 | 2016-12-22 | Immatics Biotechnologies Gmbh | Peptides and combination of peptides for use in immunotherapy and methods for generating scaffolds for the use against pancreatic cancer and other cancers |
| GB201510771D0 (en) | 2015-06-19 | 2015-08-05 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy and methods for generating scaffolds for the use against pancreatic cancer |
| GB201511191D0 (en) | 2015-06-25 | 2015-08-12 | Immatics Biotechnologies Gmbh | T-cell epitopes for the immunotherapy of myeloma |
| HK1254866A1 (zh) | 2015-06-25 | 2019-07-26 | Immatics Biotechnologies Gmbh | 用於骨髓瘤和其他癌症免疫治疗的新型细胞表位和细胞表位组合物 |
| EP3919507A3 (en) | 2015-07-01 | 2022-01-12 | Immatics Biotechnologies GmbH | Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers |
| GB201511546D0 (en) | 2015-07-01 | 2015-08-12 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers |
| CR20170579A (es) | 2015-07-06 | 2018-05-25 | Immatics Biotechnologies Gmbh | Nuevos péptidos y combinación de péptidos para usar en inmunoterapia contra el cáncer esofágico y otros cánceres. |
| GB201511792D0 (en) | 2015-07-06 | 2015-08-19 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against esopageal cancer and other cancers |
| GB201512369D0 (en) | 2015-07-15 | 2015-08-19 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against epithelial ovarian cancer and other cancers |
| MY198087A (en) | 2015-10-05 | 2023-07-31 | Immatics Biotechnologies Gmbh | Peptides and combination of peptides for use in immunotherapy against small cell lung cancer and other cancers |
| GB201517538D0 (en) | 2015-10-05 | 2015-11-18 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against small cell lung cancer and other cancers |
| EP3167898A1 (en) | 2015-11-11 | 2017-05-17 | IEO - Istituto Europeo di Oncologia Srl | Method for obtaining tumor peptides and uses thereof |
| WO2017096247A1 (en) * | 2015-12-04 | 2017-06-08 | Mayo Foundation For Medical Education And Research | Methods and vaccines for inducing immune responses to multiple different mhc molecules |
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| IL298653A (en) | 2015-12-11 | 2023-01-01 | Immatics Biotechnologies Gmbh | New peptides and a combination of peptides for use in immunotherapy against several types of cancer |
| WO2017147139A1 (en) * | 2016-02-22 | 2017-08-31 | Oceanside Biotechnology | Neoantigen compositions and methods of using the same in immunooncotherapy |
| CR20180519A (es) * | 2016-03-31 | 2019-03-05 | Neon Therapeutics Inc | Neoantígenos y métodos de su uso |
| TWI796299B (zh) * | 2016-08-26 | 2023-03-21 | 德商英麥提克生物技術股份有限公司 | 用於頭頸鱗狀細胞癌和其他癌症免疫治療的新型肽和支架 |
| DE102016123893A1 (de) | 2016-12-08 | 2018-06-14 | Immatics Biotechnologies Gmbh | T-Zellrezeptoren mit verbesserter Bindung |
| EP4317432A3 (en) | 2016-12-08 | 2024-04-17 | Immatics Biotechnologies GmbH | T cell receptors with improved pairing |
| CN106986932A (zh) * | 2017-04-06 | 2017-07-28 | 海口市人民医院 | 一种c‑Met表位肽及其应用 |
| KR102267463B1 (ko) * | 2018-02-15 | 2021-06-21 | 코쿠리츠다이가쿠호진 아사히카와 이카다이가쿠 | 암 항원 펩티드 |
| CN110804642B (zh) * | 2019-09-10 | 2022-06-21 | 清华大学 | Gpr174免疫学功能及其用途 |
| US20220387568A1 (en) * | 2019-11-14 | 2022-12-08 | Bogazici Universitesi | Asc specks in cancer immunotherapy |
| CN114524870A (zh) * | 2020-11-23 | 2022-05-24 | 香雪生命科学技术(广东)有限公司 | 源自于ssx2抗原的短肽 |
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| CN114478711B (zh) * | 2022-01-05 | 2024-10-15 | 成都朗谷生物科技股份有限公司 | 一种针对乙型肝炎病毒的抗原肽及其应用 |
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-
2005
- 2005-09-05 EP EP05019255A patent/EP1760089B1/en not_active Expired - Lifetime
- 2005-09-05 PL PL05019255T patent/PL1760089T3/pl unknown
- 2005-09-05 AT AT05019255T patent/ATE440107T1/de active
- 2005-09-05 PT PT05019255T patent/PT1760089E/pt unknown
- 2005-09-05 DE DE602005016112T patent/DE602005016112D1/de not_active Expired - Lifetime
- 2005-09-05 DK DK05019255T patent/DK1760089T3/da active
- 2005-09-05 SI SI200530796T patent/SI1760089T1/sl unknown
- 2005-09-05 ES ES05019255T patent/ES2330013T3/es not_active Expired - Lifetime
-
2006
- 2006-09-05 EA EA200800676A patent/EA013466B1/ru not_active IP Right Cessation
- 2006-09-05 DE DE602006019446T patent/DE602006019446D1/de active Active
- 2006-09-05 JP JP2008528437A patent/JP5132561B2/ja not_active Expired - Fee Related
- 2006-09-05 PT PT06777167T patent/PT1922334E/pt unknown
- 2006-09-05 WO PCT/EP2006/008641 patent/WO2007028573A1/en not_active Ceased
- 2006-09-05 ES ES06777167T patent/ES2358802T3/es active Active
- 2006-09-05 CA CA2621414A patent/CA2621414C/en not_active Expired - Fee Related
- 2006-09-05 EP EP06777167A patent/EP1922334B1/en active Active
- 2006-09-05 UA UAA201111468A patent/UA105210C2/ru unknown
- 2006-09-05 DK DK06777167.5T patent/DK1922334T3/da active
- 2006-09-05 KR KR1020087008126A patent/KR101150663B1/ko not_active Expired - Fee Related
- 2006-09-05 PL PL06777167T patent/PL1922334T3/pl unknown
- 2006-09-05 AU AU2006289289A patent/AU2006289289B2/en not_active Ceased
- 2006-09-05 SI SI200630949T patent/SI1922334T1/sl unknown
- 2006-09-05 CN CN200680038407.7A patent/CN101287755B/zh not_active Expired - Fee Related
- 2006-09-05 NZ NZ565956A patent/NZ565956A/en not_active IP Right Cessation
- 2006-09-05 BR BRPI0615466-2A patent/BRPI0615466A2/pt not_active IP Right Cessation
- 2006-09-05 US US12/065,725 patent/US20090274714A1/en not_active Abandoned
- 2006-09-05 UA UAA200803781A patent/UA97095C2/ru unknown
- 2006-09-05 HR HR20110240T patent/HRP20110240T1/xx unknown
- 2006-09-05 RS RS20110146A patent/RS51893B/sr unknown
- 2006-09-05 AT AT06777167T patent/ATE494303T1/de active
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2008
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