NO20081736L - Antitumormidler - Google Patents

Antitumormidler

Info

Publication number
NO20081736L
NO20081736L NO20081736A NO20081736A NO20081736L NO 20081736 L NO20081736 L NO 20081736L NO 20081736 A NO20081736 A NO 20081736A NO 20081736 A NO20081736 A NO 20081736A NO 20081736 L NO20081736 L NO 20081736L
Authority
NO
Norway
Prior art keywords
formula
compound
antitumor agents
salt
compounds
Prior art date
Application number
NO20081736A
Other languages
English (en)
Inventor
Thomas Hughes Corbett
Jerome P Horwitz
Stewart T Hazeldine
Lisa Polin
Original Assignee
Univ Wayne State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Wayne State filed Critical Univ Wayne State
Publication of NO20081736L publication Critical patent/NO20081736L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Oppfinnelsen stiller til rådighet forbindelser med formel I som beskrevet heri, hvori Y er F, Cl eller Br; eller et farmasøytisk akseptabelt salt derav. Forbindelsene er effektive antitumormidler. Oppfinnelsen stiller også til rådighet farmasøytiske preparater som omfatter en forbindelse med formel I eller et salt derav, mellomprodukter som er anvendelige for framstilling av en forbindelse med formel I, og terapeutisk metoder som omfatter å administrere en forbindelse med formel I eller et salt derav til pattedyr med behov for det.
NO20081736A 2005-09-09 2008-04-08 Antitumormidler NO20081736L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/223,806 US7470788B2 (en) 2005-09-07 2005-09-09 Antitumor agents
PCT/US2006/035184 WO2007030780A2 (en) 2005-09-09 2006-09-11 Quinoline derivatives and use as antitumor agents

Publications (1)

Publication Number Publication Date
NO20081736L true NO20081736L (no) 2008-06-06

Family

ID=37708463

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20081736A NO20081736L (no) 2005-09-09 2008-04-08 Antitumormidler

Country Status (16)

Country Link
US (1) US7470788B2 (no)
EP (1) EP1940794A2 (no)
JP (1) JP2009507858A (no)
KR (1) KR20080059185A (no)
CN (1) CN101258129A (no)
AU (1) AU2006287275A1 (no)
BR (1) BRPI0615583A2 (no)
CA (1) CA2621988C (no)
CR (1) CR9858A (no)
EA (1) EA200800776A1 (no)
EC (1) ECSP088237A (no)
IL (1) IL189819A0 (no)
MA (1) MA30299B1 (no)
NO (1) NO20081736L (no)
TN (1) TNSN08093A1 (no)
WO (1) WO2007030780A2 (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA007205B1 (ru) * 2001-07-31 2006-08-25 Вейне Стейт Юниверсити Производные хинолина и их использование в качестве противоопухолевых средств
US8183379B2 (en) * 2005-09-07 2012-05-22 Wayne State University Antitumor agents
US7470788B2 (en) 2005-09-07 2008-12-30 Wayne State University Antitumor agents

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6033389B2 (ja) * 1979-02-22 1985-08-02 日産化学工業株式会社 複素環エ−テル系フェノシキ脂肪酸誘導体、その製造法および該誘導体を含有する除草剤
EA007205B1 (ru) 2001-07-31 2006-08-25 Вейне Стейт Юниверсити Производные хинолина и их использование в качестве противоопухолевых средств
UA79293C2 (en) 2002-07-03 2007-06-11 Univ Wayne State 4-(7'-halo-2-quino (xa-) linyloxy)phenoxy propionic acid derivatives as antineoplastic agents
US20070054938A1 (en) 2005-09-07 2007-03-08 Horwitz Jerome P Antitumor agents
US7470788B2 (en) 2005-09-07 2008-12-30 Wayne State University Antitumor agents

Also Published As

Publication number Publication date
CA2621988A1 (en) 2007-03-15
EP1940794A2 (en) 2008-07-09
US7470788B2 (en) 2008-12-30
CR9858A (es) 2008-08-11
MA30299B1 (fr) 2009-04-01
TNSN08093A1 (en) 2009-07-14
BRPI0615583A2 (pt) 2016-11-16
EA200800776A1 (ru) 2008-10-30
CN101258129A (zh) 2008-09-03
JP2009507858A (ja) 2009-02-26
KR20080059185A (ko) 2008-06-26
ECSP088237A (es) 2008-07-30
WO2007030780A2 (en) 2007-03-15
CA2621988C (en) 2014-03-25
AU2006287275A1 (en) 2007-03-15
IL189819A0 (en) 2008-11-03
US20070060612A1 (en) 2007-03-15
WO2007030780A3 (en) 2007-09-13

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application