NO20082075L - Anti-hyperkolesterolemiske forbindelser - Google Patents
Anti-hyperkolesterolemiske forbindelserInfo
- Publication number
- NO20082075L NO20082075L NO20082075A NO20082075A NO20082075L NO 20082075 L NO20082075 L NO 20082075L NO 20082075 A NO20082075 A NO 20082075A NO 20082075 A NO20082075 A NO 20082075A NO 20082075 L NO20082075 L NO 20082075L
- Authority
- NO
- Norway
- Prior art keywords
- compounds
- cholesterol
- hypercholesterolemic compounds
- hypercholesterolemic
- esters
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 230000000326 anti-hypercholesterolaemic effect Effects 0.000 title 1
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 238000008214 LDL Cholesterol Methods 0.000 abstract 1
- 230000003143 atherosclerotic effect Effects 0.000 abstract 1
- 230000001906 cholesterol absorption Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72378105P | 2005-10-05 | 2005-10-05 | |
| PCT/US2006/038551 WO2007044318A2 (fr) | 2005-10-05 | 2006-09-29 | Composés anti-hypercholestérolémiques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20082075L true NO20082075L (no) | 2008-07-04 |
Family
ID=37845278
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20082075A NO20082075L (no) | 2005-10-05 | 2008-05-02 | Anti-hyperkolesterolemiske forbindelser |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US20090137546A1 (fr) |
| EP (1) | EP1934175B1 (fr) |
| JP (1) | JP4879991B2 (fr) |
| KR (1) | KR20080050610A (fr) |
| CN (1) | CN101277930A (fr) |
| AR (1) | AR058068A1 (fr) |
| AT (1) | ATE488495T1 (fr) |
| AU (1) | AU2006302584B2 (fr) |
| BR (1) | BRPI0616834A2 (fr) |
| CA (1) | CA2624481C (fr) |
| CR (1) | CR9903A (fr) |
| DE (1) | DE602006018341D1 (fr) |
| DO (1) | DOP2006000211A (fr) |
| EA (1) | EA200801008A1 (fr) |
| ES (1) | ES2354460T3 (fr) |
| GT (1) | GT200600444A (fr) |
| IL (1) | IL190434A0 (fr) |
| MA (1) | MA30006B1 (fr) |
| NO (1) | NO20082075L (fr) |
| PE (1) | PE20070493A1 (fr) |
| SV (1) | SV2009002863A (fr) |
| TN (1) | TNSN08153A1 (fr) |
| TW (1) | TW200806623A (fr) |
| WO (1) | WO2007044318A2 (fr) |
| ZA (1) | ZA200802587B (fr) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7176193B2 (en) * | 2002-06-19 | 2007-02-13 | Sanofi-Aventis Deutschland Gmbh | Acid-group-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use |
| GB0215579D0 (en) * | 2002-07-05 | 2002-08-14 | Astrazeneca Ab | Chemical compounds |
| EP1699760B1 (fr) * | 2003-12-23 | 2017-05-17 | Merck Sharp & Dohme Corp. | Composes anti-hypercholesterolemie |
| GB0329778D0 (en) * | 2003-12-23 | 2004-01-28 | Astrazeneca Ab | Chemical compounds |
| CA2550215A1 (fr) * | 2003-12-23 | 2005-07-07 | Astrazeneca Ab | Derives diphenylazetidinone a activite inhibitrice de l'absorption du cholesterol |
| UY29607A1 (es) * | 2005-06-20 | 2007-01-31 | Astrazeneca Ab | Compuestos quimicos |
| AR057072A1 (es) * | 2005-06-22 | 2007-11-14 | Astrazeneca Ab | Compuestos quimicos derivados de 2-azetidinona, formulacion farmaceutica y un proceso de preparacion del compuesto |
| AR057380A1 (es) * | 2005-06-22 | 2007-11-28 | Astrazeneca Ab | Compuestos quimicos derivados de 2-azetidinona y uso terapeutico de los mismos |
| AR054482A1 (es) * | 2005-06-22 | 2007-06-27 | Astrazeneca Ab | Derivados de azetidinona para el tratamiento de hiperlipidemias |
| AR057383A1 (es) * | 2005-06-22 | 2007-12-05 | Astrazeneca Ab | Compuestos quimicos derivados de 2-azetidinona, formulacion farmaceutica y un proceso de preparacion del compuesto |
| SA06270191B1 (ar) * | 2005-06-22 | 2010-03-29 | استرازينيكا ايه بي | مشتقات من 2- أزيتيدينون جديدة باعتبارها مثبطات لامتصاص الكوليسترول لعلاج حالات فرط نسبة الدهون في الدم |
| TW200806623A (en) * | 2005-10-05 | 2008-02-01 | Merck & Co Inc | Anti-hypercholesterolemic compounds |
| DE102005055726A1 (de) * | 2005-11-23 | 2007-08-30 | Sanofi-Aventis Deutschland Gmbh | Hydroxy-substituierte Diphenylazetidinone, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
| TW200811098A (en) * | 2006-04-27 | 2008-03-01 | Astrazeneca Ab | Chemical compounds |
| JP2010513485A (ja) * | 2006-12-20 | 2010-04-30 | メルク・シャープ・エンド・ドーム・コーポレイション | 抗高コレステロール血症化合物 |
| DE102009023046B4 (de) | 2008-05-30 | 2016-10-13 | Hyundai Motor Company | Automatisch schaltbares Getriebe eines Kraftfahrzeuges |
| WO2010056788A1 (fr) * | 2008-11-17 | 2010-05-20 | Merck Sharp & Dohme Corp. | Composés anti-hypercholestérolémiques |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ14294A3 (en) * | 1991-07-23 | 1994-07-13 | Schering Corp | Substituted beta-lactam compounds usable as hypocholesterol pharmaceutical preparations and process for preparing thereof |
| US5631365A (en) * | 1993-09-21 | 1997-05-20 | Schering Corporation | Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents |
| MX9606319A (es) * | 1994-06-20 | 1997-05-31 | Schering Corp | Compuestos de acetidinonas sustituidas utiles como agentes hipocolesterolemicos. |
| US5624920A (en) * | 1994-11-18 | 1997-04-29 | Schering Corporation | Sulfur-substituted azetidinone compounds useful as hypocholesterolemic agents |
| AU1609702A (en) * | 2000-12-21 | 2002-07-01 | Aventis Pharma Gmbh | Novel 1,2-diphenzylazetidinones, method for producing the same, medicaments containing said compounds, and the use thereof for treating disorders of the lipid metabolism |
| TWI291957B (en) * | 2001-02-23 | 2008-01-01 | Kotobuki Pharmaceutical Co Ltd | Beta-lactam compounds, process for repoducing the same and serum cholesterol-lowering agents containing the same |
| US7176194B2 (en) * | 2002-06-19 | 2007-02-13 | Sanofi-Aventis Deutschland Gmbh | Ring-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use |
| US7176193B2 (en) * | 2002-06-19 | 2007-02-13 | Sanofi-Aventis Deutschland Gmbh | Acid-group-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use |
| CN100439361C (zh) * | 2003-03-07 | 2008-12-03 | 先灵公司 | 取代的2-吖丁啶酮化合物、其制剂及其治疗高胆甾醇血症的用途 |
| JP2005015434A (ja) * | 2003-06-27 | 2005-01-20 | Kotobuki Seiyaku Kk | 血清コレステロール低下剤或はアテローム性硬化症の予防又は治療剤 |
| EP1699760B1 (fr) * | 2003-12-23 | 2017-05-17 | Merck Sharp & Dohme Corp. | Composes anti-hypercholesterolemie |
| WO2006086562A2 (fr) * | 2005-02-09 | 2006-08-17 | Microbia, Inc. | Derives de phenylazetidinone |
| US7696177B2 (en) * | 2005-06-15 | 2010-04-13 | Merck Sharp & Dohme Corp. | Anti-hypercholesterolemic compounds |
| TW200806623A (en) * | 2005-10-05 | 2008-02-01 | Merck & Co Inc | Anti-hypercholesterolemic compounds |
| DE102005055726A1 (de) * | 2005-11-23 | 2007-08-30 | Sanofi-Aventis Deutschland Gmbh | Hydroxy-substituierte Diphenylazetidinone, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
| MX2009003823A (es) * | 2006-11-02 | 2009-05-11 | Sanofi Aventis Deutschland | Nueva difenilazetidinona sustituida con acido piperazina-1-sulfonico y que tiene propiedades farmacologicas mejoradas. |
-
2006
- 2006-09-26 TW TW095135631A patent/TW200806623A/zh unknown
- 2006-09-27 AR ARP060104231A patent/AR058068A1/es unknown
- 2006-09-29 CN CNA2006800369359A patent/CN101277930A/zh active Pending
- 2006-09-29 BR BRPI0616834A patent/BRPI0616834A2/pt not_active IP Right Cessation
- 2006-09-29 US US11/992,990 patent/US20090137546A1/en not_active Abandoned
- 2006-09-29 EA EA200801008A patent/EA200801008A1/ru unknown
- 2006-09-29 ES ES06816084T patent/ES2354460T3/es active Active
- 2006-09-29 JP JP2008534613A patent/JP4879991B2/ja not_active Expired - Fee Related
- 2006-09-29 AT AT06816084T patent/ATE488495T1/de not_active IP Right Cessation
- 2006-09-29 CA CA2624481A patent/CA2624481C/fr not_active Expired - Fee Related
- 2006-09-29 AU AU2006302584A patent/AU2006302584B2/en not_active Ceased
- 2006-09-29 EP EP06816084A patent/EP1934175B1/fr active Active
- 2006-09-29 WO PCT/US2006/038551 patent/WO2007044318A2/fr not_active Ceased
- 2006-09-29 DE DE602006018341T patent/DE602006018341D1/de active Active
- 2006-09-29 KR KR1020087008305A patent/KR20080050610A/ko not_active Withdrawn
- 2006-10-03 PE PE2006001201A patent/PE20070493A1/es not_active Application Discontinuation
- 2006-10-03 GT GT200600444A patent/GT200600444A/es unknown
- 2006-10-04 US US11/542,966 patent/US7704988B2/en not_active Expired - Fee Related
- 2006-10-05 DO DO2006000211A patent/DOP2006000211A/es unknown
-
2008
- 2008-03-20 ZA ZA200802587A patent/ZA200802587B/xx unknown
- 2008-03-25 IL IL190434A patent/IL190434A0/en unknown
- 2008-04-04 SV SV2008002863A patent/SV2009002863A/es not_active Application Discontinuation
- 2008-04-04 TN TNP2008000153A patent/TNSN08153A1/en unknown
- 2008-04-18 CR CR9903A patent/CR9903A/es not_active Application Discontinuation
- 2008-05-02 MA MA30894A patent/MA30006B1/fr unknown
- 2008-05-02 NO NO20082075A patent/NO20082075L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US7704988B2 (en) | 2010-04-27 |
| WO2007044318A3 (fr) | 2007-07-12 |
| DE602006018341D1 (de) | 2010-12-30 |
| MA30006B1 (fr) | 2008-12-01 |
| ES2354460T3 (es) | 2011-03-15 |
| WO2007044318A2 (fr) | 2007-04-19 |
| EP1934175A2 (fr) | 2008-06-25 |
| CN101277930A (zh) | 2008-10-01 |
| TW200806623A (en) | 2008-02-01 |
| CA2624481C (fr) | 2012-04-03 |
| JP4879991B2 (ja) | 2012-02-22 |
| CR9903A (es) | 2008-07-29 |
| AR058068A1 (es) | 2008-01-23 |
| GT200600444A (es) | 2007-05-04 |
| KR20080050610A (ko) | 2008-06-09 |
| DOP2006000211A (es) | 2007-05-31 |
| JP2009511475A (ja) | 2009-03-19 |
| PE20070493A1 (es) | 2007-06-13 |
| CA2624481A1 (fr) | 2007-04-19 |
| ZA200802587B (en) | 2009-06-24 |
| AU2006302584B2 (en) | 2011-10-13 |
| TNSN08153A1 (en) | 2009-10-30 |
| SV2009002863A (es) | 2009-02-19 |
| AU2006302584A1 (en) | 2007-04-19 |
| BRPI0616834A2 (pt) | 2016-08-23 |
| US20070078098A1 (en) | 2007-04-05 |
| EP1934175B1 (fr) | 2010-11-17 |
| IL190434A0 (en) | 2008-11-03 |
| US20090137546A1 (en) | 2009-05-28 |
| EA200801008A1 (ru) | 2009-02-27 |
| ATE488495T1 (de) | 2010-12-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |