NO20082567L - Kombinasjon av ZD6474 og pemetrexed - Google Patents
Kombinasjon av ZD6474 og pemetrexedInfo
- Publication number
- NO20082567L NO20082567L NO20082567A NO20082567A NO20082567L NO 20082567 L NO20082567 L NO 20082567L NO 20082567 A NO20082567 A NO 20082567A NO 20082567 A NO20082567 A NO 20082567A NO 20082567 L NO20082567 L NO 20082567L
- Authority
- NO
- Norway
- Prior art keywords
- pemetrexed
- human
- combination
- antiangiogenic
- warm
- Prior art date
Links
- QOFFJEBXNKRSPX-ZDUSSCGKSA-N pemetrexed Chemical compound C1=N[C]2NC(N)=NC(=O)C2=C1CCC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 QOFFJEBXNKRSPX-ZDUSSCGKSA-N 0.000 title abstract 6
- 229960005079 pemetrexed Drugs 0.000 title abstract 6
- 241001465754 Metazoa Species 0.000 abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 3
- 238000004519 manufacturing process Methods 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 230000001772 anti-angiogenic effect Effects 0.000 abstract 2
- 201000011510 cancer Diseases 0.000 abstract 2
- 230000005855 radiation Effects 0.000 abstract 2
- 230000001603 reducing effect Effects 0.000 abstract 2
- 230000008728 vascular permeability Effects 0.000 abstract 2
- 239000013066 combination product Substances 0.000 abstract 1
- 229940127555 combination product Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Abstract
Foreliggende oppfinnelse angår en fremgangsmåte for frembringelse av en anti-angiogen og/eller vaskulær permeabilitetsreduserende effekt hos et varmblodig dyr slik som et menneske som eventuelt behandles med ioniserende stråling, særlig en fremgangsmåte for behandling av kreft, særlig kreft som involverer en fast tumor, som innbefatter administrasjon av ZD6474 i kombinasjon med pemetrexed; en farmasøytisk sammensetning som innbefatter ZD6474 og pemetrexed; et kombinasjonsprodukt som innbefatter ZD6474 og pemetrexed for anvendelse i en fremgangsmåte for behandling av menneske- eller dyrekroppen ved behandling, et kit som innbefatter ZD6474 og pemetrexed; anvendelsen av ZD6474 og pemetrexed for fremstilling av et medikament for anvendelse ved frembringelse av en anti-angiogen og/eller vaskulær permeabilitetsreduserende effekt hos et varmblodig dyr slik som et menneske som eventuelt behandles med ioniserende stråling. 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0526121A GB0526121D0 (en) | 2005-12-22 | 2005-12-22 | Combination therapy |
| GB0610706A GB0610706D0 (en) | 2006-05-31 | 2006-05-31 | Combination therapy |
| PCT/GB2006/004750 WO2007071958A2 (en) | 2005-12-22 | 2006-12-19 | Combination of zd6474 and pemetrexed |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20082567L true NO20082567L (no) | 2008-07-31 |
Family
ID=37814151
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20082567A NO20082567L (no) | 2005-12-22 | 2008-06-02 | Kombinasjon av ZD6474 og pemetrexed |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US20080269261A1 (no) |
| EP (1) | EP1971338B8 (no) |
| JP (1) | JP5167144B2 (no) |
| KR (1) | KR20080079675A (no) |
| AT (1) | ATE500832T1 (no) |
| AU (1) | AU2006328189B2 (no) |
| BR (1) | BRPI0620140A2 (no) |
| CA (1) | CA2631764A1 (no) |
| CY (1) | CY1111547T1 (no) |
| DE (1) | DE602006020621D1 (no) |
| DK (1) | DK1971338T3 (no) |
| HR (1) | HRP20110360T1 (no) |
| IL (1) | IL191796A0 (no) |
| NO (1) | NO20082567L (no) |
| NZ (1) | NZ568811A (no) |
| PL (1) | PL1971338T3 (no) |
| PT (1) | PT1971338E (no) |
| SI (1) | SI1971338T1 (no) |
| WO (1) | WO2007071958A2 (no) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0008269D0 (en) | 2000-04-05 | 2000-05-24 | Astrazeneca Ab | Combination chemotherapy |
| GB0126879D0 (en) * | 2001-11-08 | 2002-01-02 | Astrazeneca Ab | Combination therapy |
| GB0218526D0 (en) * | 2002-08-09 | 2002-09-18 | Astrazeneca Ab | Combination therapy |
| GB0223380D0 (en) * | 2002-10-09 | 2002-11-13 | Astrazeneca Ab | Combination therapy |
| DK1592423T3 (da) * | 2003-02-13 | 2011-06-27 | Astrazeneca Ab | Kombinationsterapi af ZD6474 med 5-FU og/eller CPT-11 |
| US20060167027A1 (en) * | 2003-07-10 | 2006-07-27 | Wedge Stephen R | Use of the quinazoline derivative zd6474 combined with platinum compounds and optionally ionising radiation in the treatment of diseases associated with angiogenesis and/or increased vascular permeability |
| GB0318422D0 (en) * | 2003-08-06 | 2003-09-10 | Astrazeneca Ab | Chemical compounds |
| MX2007003505A (es) * | 2004-09-27 | 2007-05-10 | Astrazeneca Ab | Combinacion que comprende zd6474 e imatinib. |
| GB0424339D0 (en) * | 2004-11-03 | 2004-12-08 | Astrazeneca Ab | Combination therapy |
| CA2631676A1 (en) * | 2005-12-22 | 2007-06-28 | Astrazeneca Ab | Combination of azd2171 and pemetrexed |
| DE602006020621D1 (de) * | 2005-12-22 | 2011-04-21 | Astrazeneca Ab | Kombination von zd6474 und pemetrexed |
| WO2008037996A1 (en) * | 2006-09-29 | 2008-04-03 | Astrazeneca Ab | Combination of zd6474 and bevacizumab for cancer therapy |
| US20090221615A1 (en) * | 2008-02-29 | 2009-09-03 | Guru Reddy | Combination anti-cancer agents |
| CA2789895C (en) | 2010-03-08 | 2019-04-09 | Spectrum Pharmaceuticals, Inc. | Thioxanthone-based autophagy inhibitor therapies to treat cancer |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ510991A (en) * | 1997-03-05 | 2002-11-26 | Sugen Inc | Use of formulations for hydrophobic pharmaceutical agents in treatment or prevention of cell proliferative disorders |
| GB0008269D0 (en) * | 2000-04-05 | 2000-05-24 | Astrazeneca Ab | Combination chemotherapy |
| US7001911B2 (en) * | 2000-06-28 | 2006-02-21 | Bristol-Myers Squibb Company | Fused cyclic modulators of nuclear hormone receptor function |
| ATE526019T1 (de) * | 2000-07-28 | 2011-10-15 | Sloan Kettering Inst Cancer | Verfahren zur behandlung von zellproliferationen störungen und virusinfektionen |
| GB0126879D0 (en) * | 2001-11-08 | 2002-01-02 | Astrazeneca Ab | Combination therapy |
| US20050222183A1 (en) * | 2002-08-09 | 2005-10-06 | Wedge Stephen R | Combination of zd6474, an inhibitor of the vascular endothelial growth factor receptor, with radiotherapy in the treatment of cancer |
| GB0218526D0 (en) * | 2002-08-09 | 2002-09-18 | Astrazeneca Ab | Combination therapy |
| GB0223380D0 (en) * | 2002-10-09 | 2002-11-13 | Astrazeneca Ab | Combination therapy |
| DK1592423T3 (da) * | 2003-02-13 | 2011-06-27 | Astrazeneca Ab | Kombinationsterapi af ZD6474 med 5-FU og/eller CPT-11 |
| US20060167027A1 (en) * | 2003-07-10 | 2006-07-27 | Wedge Stephen R | Use of the quinazoline derivative zd6474 combined with platinum compounds and optionally ionising radiation in the treatment of diseases associated with angiogenesis and/or increased vascular permeability |
| MX2007003505A (es) * | 2004-09-27 | 2007-05-10 | Astrazeneca Ab | Combinacion que comprende zd6474 e imatinib. |
| GB0424339D0 (en) * | 2004-11-03 | 2004-12-08 | Astrazeneca Ab | Combination therapy |
| DE602006020621D1 (de) * | 2005-12-22 | 2011-04-21 | Astrazeneca Ab | Kombination von zd6474 und pemetrexed |
| CA2631676A1 (en) * | 2005-12-22 | 2007-06-28 | Astrazeneca Ab | Combination of azd2171 and pemetrexed |
| WO2008037996A1 (en) * | 2006-09-29 | 2008-04-03 | Astrazeneca Ab | Combination of zd6474 and bevacizumab for cancer therapy |
-
2006
- 2006-12-19 DE DE602006020621T patent/DE602006020621D1/de active Active
- 2006-12-19 EP EP06820566A patent/EP1971338B8/en not_active Not-in-force
- 2006-12-19 KR KR1020087016946A patent/KR20080079675A/ko not_active Ceased
- 2006-12-19 JP JP2008546586A patent/JP5167144B2/ja not_active Expired - Fee Related
- 2006-12-19 HR HR20110360T patent/HRP20110360T1/hr unknown
- 2006-12-19 SI SI200630997T patent/SI1971338T1/sl unknown
- 2006-12-19 WO PCT/GB2006/004750 patent/WO2007071958A2/en not_active Ceased
- 2006-12-19 AT AT06820566T patent/ATE500832T1/de active
- 2006-12-19 PL PL06820566T patent/PL1971338T3/pl unknown
- 2006-12-19 CA CA002631764A patent/CA2631764A1/en not_active Abandoned
- 2006-12-19 BR BRPI0620140-7A patent/BRPI0620140A2/pt not_active Application Discontinuation
- 2006-12-19 DK DK06820566.5T patent/DK1971338T3/da active
- 2006-12-19 PT PT06820566T patent/PT1971338E/pt unknown
- 2006-12-19 US US12/158,264 patent/US20080269261A1/en not_active Abandoned
- 2006-12-19 AU AU2006328189A patent/AU2006328189B2/en not_active Ceased
- 2006-12-19 NZ NZ568811A patent/NZ568811A/en not_active IP Right Cessation
-
2008
- 2008-05-28 IL IL191796A patent/IL191796A0/en unknown
- 2008-06-02 NO NO20082567A patent/NO20082567L/no not_active Application Discontinuation
-
2010
- 2010-09-28 US US12/892,478 patent/US20110212978A1/en not_active Abandoned
-
2011
- 2011-06-08 CY CY20111100546T patent/CY1111547T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2006328189A1 (en) | 2007-06-28 |
| SI1971338T1 (sl) | 2011-06-30 |
| EP1971338B8 (en) | 2011-09-21 |
| US20110212978A1 (en) | 2011-09-01 |
| EP1971338A2 (en) | 2008-09-24 |
| JP5167144B2 (ja) | 2013-03-21 |
| US20080269261A1 (en) | 2008-10-30 |
| EP1971338B1 (en) | 2011-03-09 |
| HRP20110360T1 (hr) | 2011-06-30 |
| ATE500832T1 (de) | 2011-03-15 |
| BRPI0620140A2 (pt) | 2011-11-01 |
| CA2631764A1 (en) | 2007-06-28 |
| WO2007071958A2 (en) | 2007-06-28 |
| AU2006328189B2 (en) | 2010-01-21 |
| PT1971338E (pt) | 2011-05-09 |
| CY1111547T1 (el) | 2015-08-05 |
| WO2007071958A3 (en) | 2008-03-27 |
| DE602006020621D1 (de) | 2011-04-21 |
| JP2009520783A (ja) | 2009-05-28 |
| KR20080079675A (ko) | 2008-09-01 |
| PL1971338T3 (pl) | 2011-07-29 |
| HK1123186A1 (en) | 2009-06-12 |
| IL191796A0 (en) | 2008-12-29 |
| NZ568811A (en) | 2011-06-30 |
| DK1971338T3 (da) | 2011-05-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |