PL1971338T3 - Połączenie ZD6474 i premetreksedu - Google Patents

Połączenie ZD6474 i premetreksedu

Info

Publication number: PL1971338T3
Authority: PL; Poland
Prior art keywords: pemetrexed; human; combination; antiangiogenic; warm
Prior art date: 2005-12-22

Application number

PL06820566T

Other languages

English (en)

Inventor

Stephen Robert Wedge

Anderson Joseph Ryan

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-12-22

Filing date

2006-12-19

Publication date

2011-07-29

2005-12-22 Priority claimed from GB0526121A external-priority patent/GB0526121D0/en

2006-05-31 Priority claimed from GB0610706A external-priority patent/GB0610706D0/en

2006-12-19 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2011-07-29 Publication of PL1971338T3 publication Critical patent/PL1971338T3/pl

Links

QOFFJEBXNKRSPX-ZDUSSCGKSA-N pemetrexed Chemical compound C1=N[C]2NC(N)=NC(=O)C2=C1CCC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 QOFFJEBXNKRSPX-ZDUSSCGKSA-N 0.000 title abstract 6
229960005079 pemetrexed Drugs 0.000 title abstract 6
241001465754 Metazoa Species 0.000 abstract 3
206010028980 Neoplasm Diseases 0.000 abstract 3
238000004519 manufacturing process Methods 0.000 abstract 3
238000000034 method Methods 0.000 abstract 3
230000001772 anti-angiogenic effect Effects 0.000 abstract 2
201000011510 cancer Diseases 0.000 abstract 2
230000005855 radiation Effects 0.000 abstract 2
230000001603 reducing effect Effects 0.000 abstract 2
230000008728 vascular permeability Effects 0.000 abstract 2
239000013066 combination product Substances 0.000 abstract 1
229940127555 combination product Drugs 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Heart & Thoracic Surgery (AREA)
Oncology (AREA)
Pulmonology (AREA)
Cardiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Compositions Of Macromolecular Compounds (AREA)

PL06820566T 2005-12-22 2006-12-19 Połączenie ZD6474 i premetreksedu PL1971338T3 (pl)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GB0526121A GB0526121D0 (en)	2005-12-22	2005-12-22	Combination therapy
GB0610706A GB0610706D0 (en)	2006-05-31	2006-05-31	Combination therapy
EP06820566A EP1971338B8 (en)	2005-12-22	2006-12-19	Combination of zd6474 and pemetrexed
PCT/GB2006/004750 WO2007071958A2 (en)	2005-12-22	2006-12-19	Combination of zd6474 and pemetrexed

Publications (1)

Publication Number	Publication Date
PL1971338T3 true PL1971338T3 (pl)	2011-07-29

Family

ID=37814151

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL06820566T PL1971338T3 (pl)	2005-12-22	2006-12-19	Połączenie ZD6474 i premetreksedu

Country Status (19)

Country	Link
US (2)	US20080269261A1 (pl)
EP (1)	EP1971338B8 (pl)
JP (1)	JP5167144B2 (pl)
KR (1)	KR20080079675A (pl)
AT (1)	ATE500832T1 (pl)
AU (1)	AU2006328189B2 (pl)
BR (1)	BRPI0620140A2 (pl)
CA (1)	CA2631764A1 (pl)
CY (1)	CY1111547T1 (pl)
DE (1)	DE602006020621D1 (pl)
DK (1)	DK1971338T3 (pl)
HR (1)	HRP20110360T1 (pl)
IL (1)	IL191796A0 (pl)
NO (1)	NO20082567L (pl)
NZ (1)	NZ568811A (pl)
PL (1)	PL1971338T3 (pl)
PT (1)	PT1971338E (pl)
SI (1)	SI1971338T1 (pl)
WO (1)	WO2007071958A2 (pl)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0008269D0 (en) *	2000-04-05	2000-05-24	Astrazeneca Ab	Combination chemotherapy
GB0126879D0 (en) *	2001-11-08	2002-01-02	Astrazeneca Ab	Combination therapy
GB0218526D0 (en) *	2002-08-09	2002-09-18	Astrazeneca Ab	Combination therapy
GB0223380D0 (en) *	2002-10-09	2002-11-13	Astrazeneca Ab	Combination therapy
KR20050100683A (ko) *	2003-02-13	2005-10-19	아스트라제네카 아베	5-ｆｕ 또는/및 ｃｐｔ-11과 ｚｄ6474의 병용 요법
EP1648465B1 (en) *	2003-07-10	2010-08-25	AstraZeneca AB	Use of the quinazoline derivative zd6474 combined with platinum compounds and optionally ionising radiation in the treatment of diseases associated with angiogenesis and/or increased vascular permeability
GB0318422D0 (en) *	2003-08-06	2003-09-10	Astrazeneca Ab	Chemical compounds
KR20070072543A (ko) *	2004-09-27	2007-07-04	아스트라제네카 아베	Ｚｄ6474 및 이마티닙을 포함하는 병합법
GB0424339D0 (en) *	2004-11-03	2004-12-08	Astrazeneca Ab	Combination therapy
PL1971338T3 (pl) *	2005-12-22	2011-07-29	Astrazeneca Ab	Połączenie ZD6474 i premetreksedu
HRP20110365T1 (hr) *	2005-12-22	2011-06-30	Astrazeneca Ab	Kombinacija azd2171 i pemetrekseda
WO2008037996A1 (en) *	2006-09-29	2008-04-03	Astrazeneca Ab	Combination of zd6474 and bevacizumab for cancer therapy
US20090221615A1 (en) *	2008-02-29	2009-09-03	Guru Reddy	Combination anti-cancer agents
JP6182313B2 (ja)	2010-03-08	2017-08-16	スペクトラムファーマシューティカルズインコーポレイテッド	癌治療のためのチオキサントンをベースとしたオートファジー阻害剤療法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU743024B2 (en) *	1997-03-05	2002-01-17	Sugen, Inc.	Formulations for hydrophobic pharmaceutical agents
GB0008269D0 (en) *	2000-04-05	2000-05-24	Astrazeneca Ab	Combination chemotherapy
US7001911B2 (en) *	2000-06-28	2006-02-21	Bristol-Myers Squibb Company	Fused cyclic modulators of nuclear hormone receptor function
ATE526019T1 (de) *	2000-07-28	2011-10-15	Sloan Kettering Inst Cancer	Verfahren zur behandlung von zellproliferationen störungen und virusinfektionen
GB0126879D0 (en) *	2001-11-08	2002-01-02	Astrazeneca Ab	Combination therapy
GB0218526D0 (en) *	2002-08-09	2002-09-18	Astrazeneca Ab	Combination therapy
AU2003249000B2 (en) *	2002-08-09	2007-04-05	Astrazeneca Ab	Combination of ZD6474, an inhibitor of the vasuclar endothelial growth factor receptor, with radiotherapy in the treatment of cancer
GB0223380D0 (en) *	2002-10-09	2002-11-13	Astrazeneca Ab	Combination therapy
KR20050100683A (ko) *	2003-02-13	2005-10-19	아스트라제네카 아베	5-ｆｕ 또는/및 ｃｐｔ-11과 ｚｄ6474의 병용 요법
EP1648465B1 (en) *	2003-07-10	2010-08-25	AstraZeneca AB	Use of the quinazoline derivative zd6474 combined with platinum compounds and optionally ionising radiation in the treatment of diseases associated with angiogenesis and/or increased vascular permeability
KR20070072543A (ko) *	2004-09-27	2007-07-04	아스트라제네카 아베	Ｚｄ6474 및 이마티닙을 포함하는 병합법
GB0424339D0 (en) *	2004-11-03	2004-12-08	Astrazeneca Ab	Combination therapy
HRP20110365T1 (hr) *	2005-12-22	2011-06-30	Astrazeneca Ab	Kombinacija azd2171 i pemetrekseda
PL1971338T3 (pl) *	2005-12-22	2011-07-29	Astrazeneca Ab	Połączenie ZD6474 i premetreksedu
WO2008037996A1 (en) *	2006-09-29	2008-04-03	Astrazeneca Ab	Combination of zd6474 and bevacizumab for cancer therapy

2006
- 2006-12-19 PL PL06820566T patent/PL1971338T3/pl unknown
- 2006-12-19 NZ NZ568811A patent/NZ568811A/en not_active IP Right Cessation
- 2006-12-19 WO PCT/GB2006/004750 patent/WO2007071958A2/en not_active Ceased
- 2006-12-19 AU AU2006328189A patent/AU2006328189B2/en not_active Ceased
- 2006-12-19 JP JP2008546586A patent/JP5167144B2/ja not_active Expired - Fee Related
- 2006-12-19 SI SI200630997T patent/SI1971338T1/sl unknown
- 2006-12-19 DK DK06820566.5T patent/DK1971338T3/da active
- 2006-12-19 EP EP06820566A patent/EP1971338B8/en not_active Not-in-force
- 2006-12-19 AT AT06820566T patent/ATE500832T1/de active
- 2006-12-19 BR BRPI0620140-7A patent/BRPI0620140A2/pt not_active Application Discontinuation
- 2006-12-19 HR HR20110360T patent/HRP20110360T1/hr unknown
- 2006-12-19 KR KR1020087016946A patent/KR20080079675A/ko not_active Ceased
- 2006-12-19 CA CA002631764A patent/CA2631764A1/en not_active Abandoned
- 2006-12-19 PT PT06820566T patent/PT1971338E/pt unknown
- 2006-12-19 US US12/158,264 patent/US20080269261A1/en not_active Abandoned
- 2006-12-19 DE DE602006020621T patent/DE602006020621D1/de active Active
2008
- 2008-05-28 IL IL191796A patent/IL191796A0/en unknown
- 2008-06-02 NO NO20082567A patent/NO20082567L/no not_active Application Discontinuation
2010
- 2010-09-28 US US12/892,478 patent/US20110212978A1/en not_active Abandoned
2011
- 2011-06-08 CY CY20111100546T patent/CY1111547T1/el unknown

Also Published As

Publication number	Publication date
AU2006328189A1 (en)	2007-06-28
SI1971338T1 (sl)	2011-06-30
KR20080079675A (ko)	2008-09-01
ATE500832T1 (de)	2011-03-15
CY1111547T1 (el)	2015-08-05
DE602006020621D1 (de)	2011-04-21
JP5167144B2 (ja)	2013-03-21
BRPI0620140A2 (pt)	2011-11-01
NZ568811A (en)	2011-06-30
WO2007071958A2 (en)	2007-06-28
NO20082567L (no)	2008-07-31
DK1971338T3 (da)	2011-05-23
WO2007071958A3 (en)	2008-03-27
EP1971338A2 (en)	2008-09-24
CA2631764A1 (en)	2007-06-28
US20110212978A1 (en)	2011-09-01
IL191796A0 (en)	2008-12-29
HK1123186A1 (en)	2009-06-12
HRP20110360T1 (hr)	2011-06-30
JP2009520783A (ja)	2009-05-28
PT1971338E (pt)	2011-05-09
US20080269261A1 (en)	2008-10-30
AU2006328189B2 (en)	2010-01-21
EP1971338B1 (en)	2011-03-09
EP1971338B8 (en)	2011-09-21

Publication	Publication Date	Title
IL191796A0 (en)	2008-12-29	Combination of zd6474 and pemetrexed
GB0223380D0 (en)	2002-11-13	Combination therapy
MXPA04004355A (es)	2004-08-11	Tratamiento de combinacion que comprende zd6474 y un taxano.
MX2007003505A (es)	2007-05-10	Combinacion que comprende zd6474 e imatinib.
IL191797A0 (en)	2008-12-29	Combination of azd2171 and pemetrexed
MX2007003506A (es)	2007-05-10	Terapia de combinacion de cancer que comprende azd2171 e imatinib.
MXPA05008583A (es)	2005-11-04	Terapia de combinacion de zd6474 con 5-fu y/o cpt-11.
MX2007005356A (es)	2007-06-18	Terapia de combinacion que comprende zd6474 y un antiadrogenico.
IL172683A0 (en)	2006-04-10	Cancer combination therapy comprising azd2171 and zd1839
GB0406446D0 (en)	2004-04-28	Combination therapy
GB0406445D0 (en)	2004-04-28	Combination therapy
WO2005092384A3 (en)	2006-11-02	Combination therapy with azd2171 and a platinum anti-tumour agent
ZA200600188B (en)	2007-04-25	Combination therapy
WO2007003933A3 (en)	2007-12-27	Combination therapy of cancer with azd2171 and gemcitabine