NO20083243L - Pyrazoler for behandling av GERD og IBS - Google Patents
Pyrazoler for behandling av GERD og IBSInfo
- Publication number
- NO20083243L NO20083243L NO20083243A NO20083243A NO20083243L NO 20083243 L NO20083243 L NO 20083243L NO 20083243 A NO20083243 A NO 20083243A NO 20083243 A NO20083243 A NO 20083243A NO 20083243 L NO20083243 L NO 20083243L
- Authority
- NO
- Norway
- Prior art keywords
- treatment
- ibs
- alkyl
- hydrogen
- compounds
- Prior art date
Links
- 208000021302 gastroesophageal reflux disease Diseases 0.000 title abstract 2
- 150000003217 pyrazoles Chemical class 0.000 title abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 208000002551 irritable bowel syndrome Diseases 0.000 abstract 2
- 208000018522 Gastrointestinal disease Diseases 0.000 abstract 1
- 206010021118 Hypotonia Diseases 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000003281 allosteric effect Effects 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000036640 muscle relaxation Effects 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 230000001052 transient effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
- C07D231/40—Acylated on said nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0502908 | 2005-12-23 | ||
| PCT/SE2006/001461 WO2007073297A1 (fr) | 2005-12-23 | 2006-12-21 | Pyrazoles pour le traitement du rgop et du sii |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20083243L true NO20083243L (no) | 2008-07-23 |
Family
ID=38188928
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20083243A NO20083243L (no) | 2005-12-23 | 2008-07-22 | Pyrazoler for behandling av GERD og IBS |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20090062365A1 (fr) |
| EP (1) | EP1966150A4 (fr) |
| JP (1) | JP2009521427A (fr) |
| KR (1) | KR20080090449A (fr) |
| CN (1) | CN101341128A (fr) |
| AU (1) | AU2006327314A1 (fr) |
| BR (1) | BRPI0620415A2 (fr) |
| CA (1) | CA2632011A1 (fr) |
| IL (1) | IL191765A0 (fr) |
| NO (1) | NO20083243L (fr) |
| WO (1) | WO2007073297A1 (fr) |
| ZA (1) | ZA200805240B (fr) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0401653D0 (sv) * | 2004-06-24 | 2004-06-24 | Astrazeneca Ab | New compounds |
| EP1968946A4 (fr) * | 2005-12-23 | 2010-05-05 | Astrazeneca Ab | Imidazoles utilisés comme modulateurs des récepteurs gaba-b |
| AU2006327313A1 (en) * | 2005-12-23 | 2007-06-28 | Astrazeneca Ab | Heterocyclic GABA-B modulators |
| AU2006327315A1 (en) * | 2005-12-23 | 2007-06-28 | Astrazeneca Ab | Imidazole derivatives for the treatment of gastrointestinal disorders |
| AU2006327317B2 (en) * | 2005-12-23 | 2010-11-25 | Astrazeneca Ab | GABA-B receptor modulators |
| DK2903440T3 (en) | 2012-10-02 | 2017-12-11 | Bayer Cropscience Ag | THETEROCYCLIC COMPOUNDS AS PESTICIDES |
| TW201623257A (zh) | 2014-05-09 | 2016-07-01 | 奧利安公司 | 藥理活性之喹唑啉二酮衍生物 |
| GB202414193D0 (en) | 2024-09-27 | 2024-11-13 | Addex Pharmaceuticals Sa | Novel compounds |
| GB202414200D0 (en) | 2024-09-27 | 2024-11-13 | Addex Pharmaceuticals Sa | Novel compounds |
| GB202414199D0 (en) | 2024-09-27 | 2024-11-13 | Addex Pharmaceuticals Sa | Novel Compounds |
| GB202414192D0 (en) | 2024-09-27 | 2024-11-13 | Addex Pharmaceuticals Sa | Novel compounds |
| GB202414197D0 (en) | 2024-09-27 | 2024-11-13 | Addex Pharmaceuticals Sa | Novel compounds |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3876655A (en) * | 1971-08-18 | 1975-04-08 | Beecham Group Ltd | Anti-inflammatory acyl imidazoles |
| US3833582A (en) * | 1972-08-21 | 1974-09-03 | Pfizer | Herbicidal 1h-pyrazolo(3,4-d)pyrimidin-4-ones |
| US3910907A (en) * | 1973-07-09 | 1975-10-07 | Icn Pharmaceuticals | Pyrazolo(1,5-a)-1,3,5-triazines |
| FR2264015A1 (en) * | 1974-03-13 | 1975-10-10 | Pfizer | Pyrazolo(3,4-d)pyrimidin-4-ones - pre-and post-emergence herbicides |
| JPS5758670A (en) * | 1980-09-25 | 1982-04-08 | Otsuka Chem Co Ltd | 1-methyl-3-(n-substituted-n-chloroacetylamino)pyrazole-4-carboxylic acid ester derivative |
| US4659720A (en) * | 1982-12-20 | 1987-04-21 | Merck & Co., Inc. | 5-amino or substituted amino imidazoles useful to treat coccidiosis |
| DD240013A1 (de) * | 1985-04-01 | 1986-10-15 | Univ Halle Wittenberg | Verfahren zur herstellung von n-(1h-pyrazol-3-yl)-oxamaten |
| FR2663934B1 (fr) * | 1990-06-27 | 1994-06-03 | Adir | Nouveaux derives de l'acide 4 - amino butyrique, leur procede de preparation et les preparations pharmaceutiques qui les contiennent. |
| US5214063A (en) * | 1990-06-27 | 1993-05-25 | Adir Et Compagnie | 4-aminobutyric acid compounds, compositions and methods of use for treating disorders related to a dysfunction of GABAB receptors |
| US5201938A (en) * | 1991-07-19 | 1993-04-13 | Dowelanco | N-pyrazolyl-1,2,4-triazolo[1,5-c]pyrimidine-2-sulfonamide herbicides |
| DE4213750A1 (de) * | 1992-04-25 | 1993-10-28 | Basf Ag | Verfahren zur Herstellung von 3-(Hydroxyphenyl)-propionaldehyden und gegebenenfalls der Herstellung von 3-(hydroxyphenyl)-propanolen |
| SE9603408D0 (sv) * | 1996-09-18 | 1996-09-18 | Astra Ab | Medical use |
| US6087381A (en) * | 1997-05-22 | 2000-07-11 | G. D. Searle & Company | Pyrazole derivatives as p38 kinase inhibitors |
| US5932576A (en) * | 1997-05-22 | 1999-08-03 | G. D. Searle & Company | 3(5)-heteroaryl substituted pyrazoles as p38 kinase inhibitors |
| US6409988B1 (en) * | 1999-07-01 | 2002-06-25 | 3-Dimensional Pharmaceuticals, Inc. | Radiolabeled 1-aryl pyrazoles, the synthesis thereof and the use thereof as pest GABA receptor ligands |
| US6518266B1 (en) * | 1999-07-22 | 2003-02-11 | 3-Dimensional Pharmaceuticals | 1- Aryl-3-thioalkyl pyrazoles, the synthesis thereof and the use thereof as insecticides |
| GB0024807D0 (en) * | 2000-10-10 | 2000-11-22 | Smithkline Beecham Plc | Novel compounds |
| JP2002114765A (ja) * | 2000-10-11 | 2002-04-16 | Fuji Photo Film Co Ltd | ３−アミノ−４−カルボニルピラゾール化合物の製造方法 |
| TWI246510B (en) * | 2001-09-14 | 2006-01-01 | Mitsubishi Pharma Corp | Thiazolidine derivatives and pharmaceutical uses thereof |
| JP4623962B2 (ja) * | 2001-10-22 | 2011-02-02 | ザ・リサーチ・ファウンデーション・オブ・ステイト・ユニバーシティ・オブ・ニューヨーク | タンパク質キナーゼおよびホスファターゼ阻害剤、それらを設計する方法、ならびにそれらを使用する方法 |
| JP2003201271A (ja) * | 2001-10-25 | 2003-07-18 | Sankyo Co Ltd | 脂質モジュレーター |
| US20030139427A1 (en) * | 2002-08-23 | 2003-07-24 | Osi Pharmaceuticals Inc. | Bicyclic pyrimidinyl derivatives and methods of use thereof |
| CA2520804A1 (fr) * | 2003-04-03 | 2004-10-28 | Merck & Co., Inc. | Pyrazoles biaryle substitue utilises en tant que bloqueurs de canaux sodiques |
| SE0401653D0 (sv) * | 2004-06-24 | 2004-06-24 | Astrazeneca Ab | New compounds |
| DE102005042583A1 (de) * | 2005-09-08 | 2007-03-15 | Bayer Healthcare Ag | Iminooxazolidin-Derivate und ihre Verwendung |
| AU2006327315A1 (en) * | 2005-12-23 | 2007-06-28 | Astrazeneca Ab | Imidazole derivatives for the treatment of gastrointestinal disorders |
| AU2006327313A1 (en) * | 2005-12-23 | 2007-06-28 | Astrazeneca Ab | Heterocyclic GABA-B modulators |
| AU2006327317B2 (en) * | 2005-12-23 | 2010-11-25 | Astrazeneca Ab | GABA-B receptor modulators |
| EP1968946A4 (fr) * | 2005-12-23 | 2010-05-05 | Astrazeneca Ab | Imidazoles utilisés comme modulateurs des récepteurs gaba-b |
| US20080262064A1 (en) * | 2007-04-18 | 2008-10-23 | Astrazeneca Ab | Novel Compounds For The Treatment Of GI Disorders 682 |
| CA2682301A1 (fr) * | 2007-04-18 | 2008-10-30 | Astrazeneca Ab | Composes de xanthine ayant un effet modulateur allosterique positif du recepteur gaba b |
-
2006
- 2006-12-21 AU AU2006327314A patent/AU2006327314A1/en not_active Abandoned
- 2006-12-21 US US12/158,203 patent/US20090062365A1/en not_active Abandoned
- 2006-12-21 CA CA002632011A patent/CA2632011A1/fr not_active Abandoned
- 2006-12-21 BR BRPI0620415-5A patent/BRPI0620415A2/pt not_active IP Right Cessation
- 2006-12-21 EP EP06824531A patent/EP1966150A4/fr not_active Withdrawn
- 2006-12-21 JP JP2008547164A patent/JP2009521427A/ja active Pending
- 2006-12-21 KR KR1020087018002A patent/KR20080090449A/ko not_active Withdrawn
- 2006-12-21 WO PCT/SE2006/001461 patent/WO2007073297A1/fr not_active Ceased
- 2006-12-21 CN CNA2006800483496A patent/CN101341128A/zh active Pending
-
2008
- 2008-05-27 IL IL191765A patent/IL191765A0/en unknown
- 2008-06-17 ZA ZA200805240A patent/ZA200805240B/xx unknown
- 2008-07-22 NO NO20083243A patent/NO20083243L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| IL191765A0 (en) | 2008-12-29 |
| WO2007073297A1 (fr) | 2007-06-28 |
| US20090062365A1 (en) | 2009-03-05 |
| CN101341128A (zh) | 2009-01-07 |
| EP1966150A1 (fr) | 2008-09-10 |
| ZA200805240B (en) | 2009-04-29 |
| BRPI0620415A2 (pt) | 2011-11-08 |
| AU2006327314A1 (en) | 2007-06-28 |
| JP2009521427A (ja) | 2009-06-04 |
| KR20080090449A (ko) | 2008-10-08 |
| CA2632011A1 (fr) | 2007-06-28 |
| EP1966150A4 (fr) | 2011-07-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |