NO20084912L - Bisykliske derivater som CETP-inhibitorer - Google Patents

Bisykliske derivater som CETP-inhibitorer

Info

Publication number: NO20084912L
Authority: NO; Norway
Prior art keywords: cetp inhibitors; bicyclic derivatives; cetp; bicyclic; compounds
Prior art date: 2006-05-10

Application number

NO20084912A

Other languages

English (en)

Norwegian (no)

Inventor

Eiji Kawahara

Osamu Ohmori

Ichiro Umemura

Yuki Iwaki

Masashi Kishida

Naoko Matsuura

Hidetomo Imase

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-05-10

Filing date

2008-11-21

Publication date

2009-02-03

2006-05-10 Priority claimed from GBGB0609268.8A external-priority patent/GB0609268D0/en

2008-11-21 Application filed by Novartis Ag filed Critical Novartis Ag

2009-02-03 Publication of NO20084912L publication Critical patent/NO20084912L/no

Links

125000002619 bicyclic group Chemical group 0.000 title 1
239000003354 cholesterol ester transfer protein inhibitor Substances 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
KEWSCDNULKOKTG-UHFFFAOYSA-N 4-cyano-4-ethylsulfanylcarbothioylsulfanylpentanoic acid Chemical compound CCSC(=S)SC(C)(C#N)CCC(O)=O KEWSCDNULKOKTG-UHFFFAOYSA-N 0.000 abstract 1
102100037637 Cholesteryl ester transfer protein Human genes 0.000 abstract 1
101000880514 Homo sapiens Cholesteryl ester transfer protein Proteins 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Cardiology (AREA)
Hematology (AREA)
Heart & Thoracic Surgery (AREA)
Obesity (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Steroid Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

NO20084912A 2006-05-10 2008-11-21 Bisykliske derivater som CETP-inhibitorer NO20084912L (no)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GBGB0609268.8A GB0609268D0 (en)	2006-05-10	2006-05-10	Organic compounds
US86648006P	2006-11-20	2006-11-20
US89614207P	2007-03-21	2007-03-21
PCT/EP2007/004058 WO2007128568A1 (fr)	2006-05-10	2007-05-08	Dérivés bicycliques utilisés comme inhibiteurs de cetp

Publications (1)

Publication Number	Publication Date
NO20084912L true NO20084912L (no)	2009-02-03

Family

ID=38445602

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20084912A NO20084912L (no)	2006-05-10	2008-11-21	Bisykliske derivater som CETP-inhibitorer

Country Status (17)

Country	Link
US (2)	US8232403B2 (fr)
EP (1)	EP2024356A1 (fr)
KR (1)	KR101172120B1 (fr)
AR (1)	AR060873A1 (fr)
AU (1)	AU2007247385B2 (fr)
CA (1)	CA2650954C (fr)
CL (1)	CL2007001325A1 (fr)
CR (1)	CR10420A (fr)
EC (1)	ECSP088891A (fr)
GT (1)	GT200800242A (fr)
IL (1)	IL195010A0 (fr)
MA (1)	MA30427B1 (fr)
MX (1)	MX2008014284A (fr)
NO (1)	NO20084912L (fr)
TN (1)	TNSN08444A1 (fr)
TW (1)	TW200813009A (fr)
WO (1)	WO2007128568A1 (fr)

Families Citing this family (29)

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US8604055B2 (en)	2004-12-31	2013-12-10	Dr. Reddy's Laboratories Ltd.	Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors
CA2605214C (fr)	2004-12-31	2016-07-12	Reddy Us Therapeutics, Inc.	Nouveaux derives de benzylamine en tant qu'inhibiteurs de cetp
KR20080086917A (ko) *	2005-12-29	2008-09-26	노파르티스 아게	콜레스테릴 에스테르 전달 단백질 (ｃｅｔｐ) 억제제로서의피리디닐 아민 유도체
US8232403B2 (en) *	2006-05-10	2012-07-31	Novartis Ag	Bicyclic derivatives as CETP inhibitors
RU2008148600A (ru) *	2006-05-11	2010-06-20	Новартис АГ (CH)	Производные бензиламина в качестве ингибиторов сетр
US7750019B2 (en)	2006-08-11	2010-07-06	Kowa Company, Ltd.	Pyrimidine compound having benzyl(pyridylmethyl)amine structure and medicament comprising the same
US7790737B2 (en)	2007-03-13	2010-09-07	Kowa Company, Ltd.	Substituted pyrimidine compounds and their utility as CETP inhibitors
HUE024898T2 (en) *	2007-04-13	2016-02-29	Kowa Co	New pyrimidine compound with dibenzylamine structure and drug containing compound
EP2025674A1 (fr)	2007-08-15	2009-02-18	sanofi-aventis	Tetrahydronaphthaline substituée, son procédé de fabrication et son utilisation en tant que médicament
CN102300839B (zh)	2008-11-28	2014-12-10	兴和株式会社	反式-{4-[(烷基氨基)甲基]环己基}乙酸酯的制备方法
AU2010289397B2 (en) *	2009-09-03	2016-05-26	Bioenergenix	Heterocyclic compounds for the inhibition of PASK
EP2582709B1 (fr)	2010-06-18	2018-01-24	Sanofi	Dérivés d'azolopyridin-3-one en tant qu'inhibiteurs de lipases et de phospholipases
EP2766349B1 (fr)	2011-03-08	2016-06-01	Sanofi	Dérivés d'oxathiazine substitués par des carbocycles ou des hétérocycles, leur procédé de préparation, médicaments contenant ces composés et leur utilisation
EP2683699B1 (fr)	2011-03-08	2015-06-24	Sanofi	Dérivés oxathiazine di- et tri-substitués, procédé pour leur préparation, utilisation en tant que médicament, agent pharmaceutique contenant ces dérivés et utilisation
US8828994B2 (en)	2011-03-08	2014-09-09	Sanofi	Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
WO2012120056A1 (fr)	2011-03-08	2012-09-13	Sanofi	Dérivés oxathiazine tétra-substitués, procédé pour leur préparation, utilisation en tant que médicament, agent pharmaceutique contenant ces dérivés et utilisation
EP2683704B1 (fr)	2011-03-08	2014-12-17	Sanofi	Dérivés oxathiazine ramifiés, procédé pour leur préparation, utilisation en tant que médicament, agents pharmaceutiques contenant ces dérivés et leur utilisation
SG10201605304VA (en) *	2011-07-08	2016-08-30	Novartis Ag	Method of treating atherosclerosis in high triglyceride subjects
EP2744803A2 (fr)	2011-08-18	2014-06-25	Dr. Reddy's Laboratories Ltd.	Composés amines hétérocycliques substitués comme inhibiteurs de la protéine de transfert d'ester cholesterylique (cetp)
MX352074B (es)	2011-09-27	2017-11-08	Dr Reddys Laboratories Ltd	Derivados de 5-bencilaminometil-6-aminopirazolo [3,4-b] piridina como inhibidores de proteina de transferencia de ester de colesterilo (cetp) utiles para el tratamiento de aterosclerosis.
WO2014076568A2 (fr) *	2012-11-19	2014-05-22	Dr. Reddy's Laboratories Ltd.	Compositions pharmaceutiques d'inhibiteurs de cetp
UY35144A (es)	2012-11-20	2014-06-30	Novartis Ag	Miméticos lineales sintéticos de apelina para el tratamiento de insuficiencia cardiaca
WO2014128564A2 (fr) *	2013-02-21	2014-08-28	Dr. Reddy's Laboratories Ltd.	Compositions pharmaceutiques d'inhibiteurs cetp
KR20160031551A (ko)	2013-07-25	2016-03-22	노파르티스 아게	심부전의 치료를 위한 시클릭 폴리펩티드
HK1218252A1 (zh)	2013-07-25	2017-02-10	Novartis Ag	合成apelin多肽之生物结合物
MA41580A (fr)	2015-01-23	2017-11-29	Novartis Ag	Conjugués d'acides gras de l'apeline synthétique présentant une demi-vie améliorée
US12162863B2 (en)	2018-06-12	2024-12-10	Ryvu Therapeutics S.A.	Modulators of stimulator of interferon genes (STING)
BR112021024948A2 (pt)	2019-06-12	2022-01-25	Ryvu Therapeutics S A	Moduladores de próxima geração de estimulador de genes de interferon (sting)
EP4073063A1 (fr) *	2019-12-11	2022-10-19	Ryvu Therapeutics S.A.	Composés hétérocycliques en tant que modulateurs du stimulateur des gènes de l'interféron (sting)

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PY0119496A (es) *	2000-08-07	2003-11-03	Neurogen Corp	Compuestos heterociclicos como ligandos de receptores gabaa
US7332514B2 (en) *	2002-08-30	2008-02-19	Japan Tobacco Inc.	Dibenzylamine compound and medicinal use thereof
AU2003291403A1 (en)	2002-11-08	2004-06-03	Neurogen Corporation	3-substituted-6-aryl pyridined as ligands of c5a receptors
JP2006521344A (ja)	2003-03-28	2006-09-21	ファイザー・プロダクツ・インク	アテローム性動脈硬化症および肥満の治療のためのｃｅｔｐ阻害剤としての１，２，４−置換１，２，３，４−テトラヒドロ−および１，２−ジヒドロ−キノリンおよび１，２，３，４−テトラヒドロ−キノキサリン誘導体
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CA2562082C (fr)	2004-04-13	2013-06-25	Merck & Co., Inc.	Inhibiteurs de la cetp pour le traitement et la prevention de l'atherosclerose
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WO2007075194A1 (fr)	2005-12-28	2007-07-05	Reddy Us Therapeutics, Inc.	Derives de benzylamine selectifs et leur utilite en tant qu’inhibiteurs de la proteine de transfert de l'ester de cholesterol
EP1834490A1 (fr)	2005-01-06	2007-09-19	Thomson Licensing	Reduction d'artefacts d'arc-en-ciel dans des systemes numeriques de projection de lumiere
WO2007007519A1 (fr)	2005-07-07	2007-01-18	Sony Corporation	Procédé d'acquisition d'informations sur une substance et dispositif de mesure d'informations sur une substance utilisant une lumière évanescente, ainsi que procédé et dispositif de décision concernant une disposition de base
WO2007008899A2 (fr)	2005-07-11	2007-01-18	University Of Florida Research Foundation, Inc.	Division de champ d'adoucissement variable de champs modules en intensite de grande dimension
KR20080086917A (ko) *	2005-12-29	2008-09-26	노파르티스 아게	콜레스테릴 에스테르 전달 단백질 (ｃｅｔｐ) 억제제로서의피리디닐 아민 유도체
UY30118A1 (es)	2006-01-31	2007-06-29	Tanabe Seiyaku Co	Compueto amina trisustituido
US8232403B2 (en) *	2006-05-10	2012-07-31	Novartis Ag	Bicyclic derivatives as CETP inhibitors
RU2008148600A (ru) *	2006-05-11	2010-06-20	Новартис АГ (CH)	Производные бензиламина в качестве ингибиторов сетр
CN101535293A (zh) *	2006-11-15	2009-09-16	诺瓦提斯公司	作为cetp抑制剂的杂环衍生物
JP2010509388A (ja) *	2006-11-15	2010-03-25	ノバルティスアーゲー	有機化合物

2007
- 2007-05-08 US US12/300,208 patent/US8232403B2/en not_active Expired - Fee Related
- 2007-05-08 KR KR1020087030049A patent/KR101172120B1/ko not_active Expired - Fee Related
- 2007-05-08 MX MX2008014284A patent/MX2008014284A/es active IP Right Grant
- 2007-05-08 CA CA2650954A patent/CA2650954C/fr not_active Expired - Fee Related
- 2007-05-08 AR ARP070101992A patent/AR060873A1/es unknown
- 2007-05-08 WO PCT/EP2007/004058 patent/WO2007128568A1/fr not_active Ceased
- 2007-05-08 AU AU2007247385A patent/AU2007247385B2/en not_active Ceased
- 2007-05-08 EP EP07724982A patent/EP2024356A1/fr not_active Withdrawn
- 2007-05-09 CL CL200701325A patent/CL2007001325A1/es unknown
- 2007-05-09 TW TW096116482A patent/TW200813009A/zh unknown
2008
- 2008-10-30 IL IL195010A patent/IL195010A0/en unknown
- 2008-10-30 CR CR10420A patent/CR10420A/es not_active Application Discontinuation
- 2008-11-06 TN TNP2008000444A patent/TNSN08444A1/en unknown
- 2008-11-07 GT GT200800242A patent/GT200800242A/es unknown
- 2008-11-10 EC EC2008008891A patent/ECSP088891A/es unknown
- 2008-11-21 NO NO20084912A patent/NO20084912L/no not_active Application Discontinuation
- 2008-11-24 MA MA31408A patent/MA30427B1/fr unknown
2012
- 2012-05-17 US US13/473,649 patent/US8410275B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
KR101172120B1 (ko)	2012-08-10
US8410275B2 (en)	2013-04-02
CA2650954A1 (fr)	2007-11-15
ECSP088891A (es)	2008-12-30
TW200813009A (en)	2008-03-16
US8232403B2 (en)	2012-07-31
KR20090017580A (ko)	2009-02-18
CA2650954C (fr)	2014-02-11
AR060873A1 (es)	2008-07-16
EP2024356A1 (fr)	2009-02-18
AU2007247385B2 (en)	2011-07-14
IL195010A0 (en)	2009-08-03
US20120225874A1 (en)	2012-09-06
GT200800242A (es)	2009-04-29
CR10420A (es)	2009-02-02
US20090227580A1 (en)	2009-09-10
AU2007247385A1 (en)	2007-11-15
TNSN08444A1 (en)	2010-04-14
WO2007128568A1 (fr)	2007-11-15
MX2008014284A (es)	2008-11-18
MA30427B1 (fr)	2009-05-04
CL2007001325A1 (es)	2008-07-18

Legal Events

Date	Code	Title	Description
2010-12-27	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO20084912L (no)	2009-02-03	Bisykliske derivater som CETP-inhibitorer
NO20080675L (no)	2008-03-13	P38-Map kinaseinhibitorer og metoder for deres anvendelse
NO20090628L (no)	2009-04-21	Pyridizinon derivativater
NO20075082L (no)	2007-10-31	Pyridin-3-karboksamidderivater som CB1-inversagonister
NO20083427L (no)	2008-10-14	Cystoksiske midler omfattende nye tomaymycinderivater og deres terapeutiske anvendelse
NO20062561L (no)	2006-09-08	Kinoliner nyttige for behandling av kardiovaskulaere sykdommer
MX2009006535A (es)	2009-06-26	Derivados de indol-4-il-pirimidinil-2-il-amina y su uso como inhibidores de cinasa dependiente de ciclina.
NO20090216L (no)	2009-03-12	Forbindelser med CRTH2 antagonistaktivitet
NO20076066L (no)	2008-01-07	Oksadiazolderivater som DGAT-inhibitorer
NO20061454L (no)	2006-07-06	Compounds having CRTH2 antagonist activity
NO20084502L (no)	2008-11-26	Tetrahydropyrrolopyrimidinedioner og deres anvendelse som humane neutrofil elastase inhibitorer
UY29246A1 (es)	2006-08-31	Nuevos compuestos
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NO20082090L (no)	2008-05-20	Pyridopyrimidinoninhibitorer av P13K alfa
NO20070855L (no)	2007-03-19	Arylidener for behandling av estrogenrelaterte reseptor-alfamedierte sykdommer.
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NO20092692L (no)	2009-09-16	MAPK/ERK kinaseinhibitorer
NO20083923L (no)	2008-11-04	Pyrazolkinoloner er potente parp-inhibitorer
PT1940839E (pt)	2013-10-10	Inibidores de piridopirimidinona pi3k alfa
NO20090295L (no)	2009-01-20	Substituerte heteroarylderivater
NO20070933L (no)	2007-03-28	Indazoler anvendbare i behandling av kardiovaskulaere sykdommer
NO20066055L (no)	2007-01-24	Pyridinderivater
NO20090756L (no)	2009-04-14	Amino-piperidinderivater som CETP-inhibitorer
CL2008002954A1 (es)	2010-01-15	Compuestos derivados de 1,2,3,3a,3b,4,5,7,10,10a,10b,11,12,12a-tetradecahidrociclopenta-(5,6)nafto-(1,2-f)indazol heterociclo o carbociclo sustituido; procedimiento de preparacion; composicion farmaceutica; y su uso en el tratamiento de asma, epoc, rinits alergica.
NO20082096L (no)	2008-05-29	Azaindol-2-karboksamidderivativer