NO20084913L - Sammensetning inneholdende en jernchelator og et anti-neoplatisk middel og anvendelse derav - Google Patents
Sammensetning inneholdende en jernchelator og et anti-neoplatisk middel og anvendelse deravInfo
- Publication number
- NO20084913L NO20084913L NO20084913A NO20084913A NO20084913L NO 20084913 L NO20084913 L NO 20084913L NO 20084913 A NO20084913 A NO 20084913A NO 20084913 A NO20084913 A NO 20084913A NO 20084913 L NO20084913 L NO 20084913L
- Authority
- NO
- Norway
- Prior art keywords
- composition containing
- neoplastic agent
- iron chelator
- combination
- triazolyl
- Prior art date
Links
- 229940034982 antineoplastic agent Drugs 0.000 title abstract 2
- 239000002246 antineoplastic agent Substances 0.000 title abstract 2
- OEUUFNIKLCFNLN-LLVKDONJSA-N chembl432481 Chemical compound OC(=O)[C@@]1(C)CSC(C=2C(=CC(O)=CC=2)O)=N1 OEUUFNIKLCFNLN-LLVKDONJSA-N 0.000 title 1
- KPKQWXGFEKRQQA-UHFFFAOYSA-N 3,5-diphenyl-1h-1,2,4-triazole Chemical class C1=CC=CC=C1C1=NNC(C=2C=CC=CC=2)=N1 KPKQWXGFEKRQQA-UHFFFAOYSA-N 0.000 abstract 1
- BOFQWVMAQOTZIW-UHFFFAOYSA-N deferasirox Chemical compound C1=CC(C(=O)O)=CC=C1N1C(C=2C(=CC=CC=2)O)=NC(C=2C(=CC=CC=2)O)=N1 BOFQWVMAQOTZIW-UHFFFAOYSA-N 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/282—Platinum compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74678806P | 2006-05-09 | 2006-05-09 | |
| PCT/EP2007/054456 WO2007128820A1 (en) | 2006-05-09 | 2007-05-08 | Combination comprising an iron chelator and an anti-neoplastic agent and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20084913L true NO20084913L (no) | 2009-02-05 |
Family
ID=38282831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20084913A NO20084913L (no) | 2006-05-09 | 2008-11-21 | Sammensetning inneholdende en jernchelator og et anti-neoplatisk middel og anvendelse derav |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US20090317489A1 (pt) |
| EP (2) | EP2272511A1 (pt) |
| JP (1) | JP2009536180A (pt) |
| KR (1) | KR20090007635A (pt) |
| CN (1) | CN101443002B (pt) |
| AU (1) | AU2007247112B2 (pt) |
| BR (1) | BRPI0711385A2 (pt) |
| CA (1) | CA2649792A1 (pt) |
| IL (1) | IL194819A0 (pt) |
| MA (1) | MA31130B1 (pt) |
| MX (1) | MX2008014292A (pt) |
| NO (1) | NO20084913L (pt) |
| NZ (1) | NZ572299A (pt) |
| RU (1) | RU2469721C2 (pt) |
| TN (1) | TNSN08447A1 (pt) |
| WO (1) | WO2007128820A1 (pt) |
| ZA (1) | ZA200808961B (pt) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2254599A2 (en) * | 2008-02-19 | 2010-12-01 | Novartis AG | Combination of an iron chelator and an immunosuppressant and use thereof |
| US20130011411A1 (en) * | 2010-01-06 | 2013-01-10 | Pestell Richard G | Methods and compositions for the diagnosis, prognosis, and treatment of cancer |
| ES2681703T3 (es) * | 2011-03-21 | 2018-09-14 | Vivolux Ab | Tratamiento de tumores sólidos |
| EP2900667B1 (en) | 2012-09-21 | 2019-06-05 | Vivolux AB | Means and method for treating solid tumours |
| CN104860941B (zh) * | 2014-02-25 | 2017-03-22 | 上海海雁医药科技有限公司 | 2,4‑二取代苯‑1,5‑二胺衍生物及其应用以及由其制备的药物组合物和药用组合物 |
| CN110075120B (zh) * | 2018-10-11 | 2022-03-11 | 广东众尔健生物科技有限公司 | 一种组合物及其在抗肿瘤药物中的应用 |
| CN114073772A (zh) * | 2020-08-18 | 2022-02-22 | 上海市公共卫生临床中心 | 铁螯合剂在制备用于治疗或预防多瘤病毒感染的药物中的用途 |
Family Cites Families (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2182943A1 (en) | 1972-04-10 | 1973-12-14 | Rustenburg Platinum Mines Ltd | Cis-dihalo-bis(ethyleneimine) platinum (ii) derivs - anti-cancer agents |
| CH605550A5 (pt) | 1972-06-08 | 1978-09-29 | Research Corp | |
| GB1524747A (en) | 1976-05-11 | 1978-09-13 | Ici Ltd | Polypeptide |
| DE3372965D1 (en) | 1982-07-23 | 1987-09-17 | Ici Plc | Amide derivatives |
| GB8327256D0 (en) | 1983-10-12 | 1983-11-16 | Ici Plc | Steroid derivatives |
| GB8517360D0 (en) | 1985-07-09 | 1985-08-14 | Erba Farmitalia | Substituted androsta-1,4-diene-3,17-diones |
| GB8528983D0 (en) * | 1985-11-25 | 1986-01-02 | Ciba Geigy Ag | Use of chelating agents |
| EP0227593A1 (en) * | 1985-11-25 | 1987-07-01 | The Hospital For Sick Children | Use of chelating agents |
| US5093330A (en) | 1987-06-15 | 1992-03-03 | Ciba-Geigy Corporation | Staurosporine derivatives substituted at methylamino nitrogen |
| US4939168A (en) | 1989-08-11 | 1990-07-03 | Harbor Branch Oceanographics Institution, Inc. | Discodermolide compounds, compositions containing same and methods of preparation and use |
| US5395855A (en) | 1990-05-07 | 1995-03-07 | Ciba-Geigy Corporation | Hydrazones |
| NZ243082A (en) | 1991-06-28 | 1995-02-24 | Ici Plc | 4-anilino-quinazoline derivatives; pharmaceutical compositions, preparatory processes, and use thereof |
| AU661533B2 (en) | 1992-01-20 | 1995-07-27 | Astrazeneca Ab | Quinazoline derivatives |
| TW225528B (pt) | 1992-04-03 | 1994-06-21 | Ciba Geigy Ag | |
| KR100335584B1 (ko) | 1992-10-28 | 2002-11-29 | 제넨테크, 인코포레이티드 | 혈관내피세포성장인자에대한길항제 |
| GB9314893D0 (en) | 1993-07-19 | 1993-09-01 | Zeneca Ltd | Quinazoline derivatives |
| GB9315802D0 (en) | 1993-07-30 | 1993-09-15 | Roussel Lab Ltd | Chemical compounds |
| AU2989695A (en) | 1994-08-08 | 2000-03-07 | Debiopharm S.A. | Pharmaceutically stable oxaliplatinum preparation |
| US5618487A (en) | 1995-02-21 | 1997-04-08 | Hettinga; Siebolt | Multi-clamp mold and method for clamping an injection mold assembly |
| ATE446955T1 (de) | 1995-03-30 | 2009-11-15 | Pfizer Prod Inc | Chinazolinone derivate |
| GB9508538D0 (en) | 1995-04-27 | 1995-06-14 | Zeneca Ltd | Quinazoline derivatives |
| US5747498A (en) | 1996-05-28 | 1998-05-05 | Pfizer Inc. | Alkynyl and azido-substituted 4-anilinoquinazolines |
| US5880141A (en) | 1995-06-07 | 1999-03-09 | Sugen, Inc. | Benzylidene-Z-indoline compounds for the treatment of disease |
| US5843901A (en) | 1995-06-07 | 1998-12-01 | Advanced Research & Technology Institute | LHRH antagonist peptides |
| PL188959B1 (pl) | 1995-07-06 | 2005-05-31 | Novartis Ag | Pirolopirymidyny i sposoby ich wytwarzania |
| US5760041A (en) | 1996-02-05 | 1998-06-02 | American Cyanamid Company | 4-aminoquinazoline EGFR Inhibitors |
| GB9603095D0 (en) | 1996-02-14 | 1996-04-10 | Zeneca Ltd | Quinazoline derivatives |
| CN100503580C (zh) | 1996-04-12 | 2009-06-24 | 沃尼尔·朗伯公司 | 酪氨酸激酶的不可逆抑制剂 |
| BR9709959A (pt) | 1996-06-24 | 2000-05-09 | Pfizer | Derivados tricìclicos de fenilamino substituìdo para o tratamento de doenças hiperproliferativas |
| MY129541A (en) * | 1996-06-25 | 2007-04-30 | Novartis Ag | Substituded 3,5-diphenyl-1,2,4-triazoles and their use as pharmaceutical metal chelators |
| AU716610B2 (en) | 1996-08-30 | 2000-03-02 | Novartis Ag | Method for producing epothilones, and intermediate products obtained during the production process |
| DE938597T1 (de) | 1996-09-06 | 2000-03-09 | Obducat Ab | Verfahren für das anisotrope ätzen von strukturen in leitende materialien |
| DE19638745C2 (de) | 1996-09-11 | 2001-05-10 | Schering Ag | Monoklonale Antikörper gegen die extrazelluläre Domäne des menschlichen VEGF - Rezeptorproteins (KDR) |
| WO1998010767A2 (en) | 1996-09-13 | 1998-03-19 | Sugen, Inc. | Use of quinazoline derivatives for the manufacture of a medicament in the treatment of hyperproliferative skin disorders |
| EP0837063A1 (en) | 1996-10-17 | 1998-04-22 | Pfizer Inc. | 4-Aminoquinazoline derivatives |
| ATE267197T1 (de) | 1996-11-18 | 2004-06-15 | Biotechnolog Forschung Gmbh | Epothilon d, dessen herstellung und dessen verwendung als cytostatisches mittel bzw. als pflanzenschutzmittel |
| US5789605A (en) | 1996-12-03 | 1998-08-04 | Trustees Of The University Of Pennsylvania | Synthetic techniques and intermediates for polyhydroxy, dienyl lactones and mimics thereof |
| US6441186B1 (en) | 1996-12-13 | 2002-08-27 | The Scripps Research Institute | Epothilone analogs |
| CO4950519A1 (es) | 1997-02-13 | 2000-09-01 | Novartis Ag | Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion |
| CO4940418A1 (es) | 1997-07-18 | 2000-07-24 | Novartis Ag | Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso |
| GB9721069D0 (en) | 1997-10-03 | 1997-12-03 | Pharmacia & Upjohn Spa | Polymeric derivatives of camptothecin |
| US6194181B1 (en) | 1998-02-19 | 2001-02-27 | Novartis Ag | Fermentative preparation process for and crystal forms of cytostatics |
| CA2322157C (en) | 1998-02-25 | 2012-05-29 | Sloan-Kettering Institute For Cancer Research | Synthesis of epothilones, intermediates thereto and analogues thereof |
| ES2342240T3 (es) | 1998-08-11 | 2010-07-02 | Novartis Ag | Derivados de isoquinolina con actividad que inhibe la angiogenia. |
| UA71587C2 (uk) | 1998-11-10 | 2004-12-15 | Шерінг Акцієнгезелльшафт | Аміди антранілової кислоти та їхнє застосування як лікарських засобів |
| GB9824579D0 (en) | 1998-11-10 | 1999-01-06 | Novartis Ag | Organic compounds |
| CN100381566C (zh) | 1998-11-20 | 2008-04-16 | 科森生物科学公司 | 产生环氧噻酮及其衍生物的重组方法和材料 |
| EP1579871A1 (en) | 1998-12-22 | 2005-09-28 | Genentech, Inc. | Vascular endothelial cell growth factor antagonists and uses thereof |
| ATE329596T1 (de) | 1999-03-30 | 2006-07-15 | Novartis Pharma Gmbh | Phthalazinderivate zur behandlung von entzündlicher erkrankungen |
| US6645990B2 (en) * | 2000-08-15 | 2003-11-11 | Amgen Inc. | Thiazolyl urea compounds and methods of uses |
| PE20020354A1 (es) | 2000-09-01 | 2002-06-12 | Novartis Ag | Compuestos de hidroxamato como inhibidores de histona-desacetilasa (hda) |
| TWI238824B (en) | 2001-05-14 | 2005-09-01 | Novartis Ag | 4-amino-5-phenyl-7-cyclobutyl-pyrrolo[2,3-d]pyrimidine derivatives |
| GB0119249D0 (en) | 2001-08-07 | 2001-10-03 | Novartis Ag | Organic compounds |
| TWI272273B (en) * | 2002-07-16 | 2007-02-01 | Sonus Pharma Inc | Platinum compounds |
| GB0223978D0 (en) | 2002-10-15 | 2002-11-20 | Novartis Ag | Organic compound |
| CA2515424A1 (en) * | 2003-02-06 | 2004-08-26 | Bioresponse, Llc | The combined use of cruciferous indoles and chelators for the treatment of papillomavirus-related conditions |
| ES2436524T3 (es) * | 2003-05-22 | 2014-01-02 | Nerviano Medical Sciences S.R.L. | Derivados de pirazolo-quinazolina, procedimiento para su preparación y su uso como inhibidores de cinasas |
| GB0408078D0 (en) | 2004-04-08 | 2004-05-12 | Novartis Ag | Organic compounds |
| CN101111237A (zh) * | 2005-02-10 | 2008-01-23 | 诺瓦提斯公司 | 改善药物处置的方法 |
-
2007
- 2007-05-08 JP JP2009508375A patent/JP2009536180A/ja active Pending
- 2007-05-08 NZ NZ572299A patent/NZ572299A/en not_active IP Right Cessation
- 2007-05-08 RU RU2008148167/15A patent/RU2469721C2/ru not_active IP Right Cessation
- 2007-05-08 CA CA002649792A patent/CA2649792A1/en not_active Abandoned
- 2007-05-08 BR BRPI0711385-4A patent/BRPI0711385A2/pt not_active IP Right Cessation
- 2007-05-08 WO PCT/EP2007/054456 patent/WO2007128820A1/en not_active Ceased
- 2007-05-08 CN CN2007800168674A patent/CN101443002B/zh not_active Expired - Fee Related
- 2007-05-08 AU AU2007247112A patent/AU2007247112B2/en not_active Ceased
- 2007-05-08 EP EP10174260A patent/EP2272511A1/en not_active Withdrawn
- 2007-05-08 EP EP07728908A patent/EP2026800A1/en not_active Withdrawn
- 2007-05-08 US US12/226,851 patent/US20090317489A1/en not_active Abandoned
- 2007-05-08 KR KR1020087029889A patent/KR20090007635A/ko not_active Ceased
- 2007-05-08 MX MX2008014292A patent/MX2008014292A/es active IP Right Grant
-
2008
- 2008-10-20 ZA ZA200808961A patent/ZA200808961B/xx unknown
- 2008-10-22 IL IL194819A patent/IL194819A0/en unknown
- 2008-11-06 TN TNP2008000447A patent/TNSN08447A1/en unknown
- 2008-11-21 NO NO20084913A patent/NO20084913L/no not_active Application Discontinuation
- 2008-11-24 MA MA31409A patent/MA31130B1/fr unknown
-
2011
- 2011-03-10 US US13/044,596 patent/US20110159114A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN101443002A (zh) | 2009-05-27 |
| CA2649792A1 (en) | 2007-11-15 |
| EP2026800A1 (en) | 2009-02-25 |
| MA31130B1 (fr) | 2010-02-01 |
| NZ572299A (en) | 2010-07-30 |
| IL194819A0 (en) | 2009-08-03 |
| RU2008148167A (ru) | 2010-06-20 |
| EP2272511A1 (en) | 2011-01-12 |
| WO2007128820A1 (en) | 2007-11-15 |
| BRPI0711385A2 (pt) | 2011-11-08 |
| JP2009536180A (ja) | 2009-10-08 |
| TNSN08447A1 (en) | 2010-04-14 |
| CN101443002B (zh) | 2012-03-21 |
| AU2007247112B2 (en) | 2010-08-26 |
| KR20090007635A (ko) | 2009-01-19 |
| MX2008014292A (es) | 2008-11-18 |
| US20110159114A1 (en) | 2011-06-30 |
| AU2007247112A1 (en) | 2007-11-15 |
| RU2469721C2 (ru) | 2012-12-20 |
| US20090317489A1 (en) | 2009-12-24 |
| ZA200808961B (en) | 2009-08-26 |
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