MA31130B1 - Combinaison comprenant un chelatant du fer et un agent antineoplasique et ses applications - Google Patents

Combinaison comprenant un chelatant du fer et un agent antineoplasique et ses applications

Info

Publication number
MA31130B1
MA31130B1 MA31409A MA31409A MA31130B1 MA 31130 B1 MA31130 B1 MA 31130B1 MA 31409 A MA31409 A MA 31409A MA 31409 A MA31409 A MA 31409A MA 31130 B1 MA31130 B1 MA 31130B1
Authority
MA
Morocco
Prior art keywords
combination
antineoplastic agent
chelatant
iron
applications
Prior art date
Application number
MA31409A
Other languages
Arabic (ar)
English (en)
Inventor
Hanspeter Nick
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MA31130B1 publication Critical patent/MA31130B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/282—Platinum compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La présente invention concerne une combinaison comprenant (a) un 3,5-diphényl-1,2,4-triazole substitué, par exemple l'acide 4-[3,5-bis(2-hydroxyphényl)-[1,2,4]triazol-1-yl]benzoïque et au moins un agent antinéoplasique, et l'emploi d'une telle combinaison dans l'élaboration d'un médicament destiné au traitement de maladies prolifératives
MA31409A 2006-05-09 2008-11-24 Combinaison comprenant un chelatant du fer et un agent antineoplasique et ses applications MA31130B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74678806P 2006-05-09 2006-05-09
PCT/EP2007/054456 WO2007128820A1 (fr) 2006-05-09 2007-05-08 Combinaison comprenant un chélatant du fer et un agent antinéoplasique et ses applications

Publications (1)

Publication Number Publication Date
MA31130B1 true MA31130B1 (fr) 2010-02-01

Family

ID=38282831

Family Applications (1)

Application Number Title Priority Date Filing Date
MA31409A MA31130B1 (fr) 2006-05-09 2008-11-24 Combinaison comprenant un chelatant du fer et un agent antineoplasique et ses applications

Country Status (17)

Country Link
US (2) US20090317489A1 (fr)
EP (2) EP2272511A1 (fr)
JP (1) JP2009536180A (fr)
KR (1) KR20090007635A (fr)
CN (1) CN101443002B (fr)
AU (1) AU2007247112B2 (fr)
BR (1) BRPI0711385A2 (fr)
CA (1) CA2649792A1 (fr)
IL (1) IL194819A0 (fr)
MA (1) MA31130B1 (fr)
MX (1) MX2008014292A (fr)
NO (1) NO20084913L (fr)
NZ (1) NZ572299A (fr)
RU (1) RU2469721C2 (fr)
TN (1) TNSN08447A1 (fr)
WO (1) WO2007128820A1 (fr)
ZA (1) ZA200808961B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2010009104A (es) * 2008-02-19 2010-09-09 Novartis Ag Combinacion de un quelante de hierro y un inmunosupresor y uso de la misma.
WO2011085134A2 (fr) * 2010-01-06 2011-07-14 Georgetown University Méthodes et compositions pour le diagnostic, le pronostic et le traitement du cancer
ES2681703T3 (es) 2011-03-21 2018-09-14 Vivolux Ab Tratamiento de tumores sólidos
EP2900667B1 (fr) 2012-09-21 2019-06-05 Vivolux AB Moyens et procédé pour traiter des tumeurs solides
CN104860941B (zh) * 2014-02-25 2017-03-22 上海海雁医药科技有限公司 2,4‑二取代苯‑1,5‑二胺衍生物及其应用以及由其制备的药物组合物和药用组合物
CN110075120B (zh) * 2018-10-11 2022-03-11 广东众尔健生物科技有限公司 一种组合物及其在抗肿瘤药物中的应用
CN114073772A (zh) * 2020-08-18 2022-02-22 上海市公共卫生临床中心 铁螯合剂在制备用于治疗或预防多瘤病毒感染的药物中的用途

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Also Published As

Publication number Publication date
CA2649792A1 (fr) 2007-11-15
EP2026800A1 (fr) 2009-02-25
NZ572299A (en) 2010-07-30
US20090317489A1 (en) 2009-12-24
IL194819A0 (en) 2009-08-03
EP2272511A1 (fr) 2011-01-12
ZA200808961B (en) 2009-08-26
WO2007128820A1 (fr) 2007-11-15
RU2008148167A (ru) 2010-06-20
US20110159114A1 (en) 2011-06-30
TNSN08447A1 (en) 2010-04-14
AU2007247112A1 (en) 2007-11-15
AU2007247112B2 (en) 2010-08-26
NO20084913L (no) 2009-02-05
MX2008014292A (es) 2008-11-18
RU2469721C2 (ru) 2012-12-20
BRPI0711385A2 (pt) 2011-11-08
KR20090007635A (ko) 2009-01-19
JP2009536180A (ja) 2009-10-08
CN101443002B (zh) 2012-03-21
CN101443002A (zh) 2009-05-27

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