NO20084987L - Belagt farmasoytisk produkt for intraoral avlevering av nikotin innbefattende trometamol som bufringsmiddel - Google Patents
Belagt farmasoytisk produkt for intraoral avlevering av nikotin innbefattende trometamol som bufringsmiddelInfo
- Publication number
- NO20084987L NO20084987L NO20084987A NO20084987A NO20084987L NO 20084987 L NO20084987 L NO 20084987L NO 20084987 A NO20084987 A NO 20084987A NO 20084987 A NO20084987 A NO 20084987A NO 20084987 L NO20084987 L NO 20084987L
- Authority
- NO
- Norway
- Prior art keywords
- nicotine
- trometamol
- pharmaceutical product
- buffering agent
- delivery
- Prior art date
Links
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 title abstract 6
- 229960002715 nicotine Drugs 0.000 title abstract 6
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 title abstract 6
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 title abstract 2
- 229960000281 trometamol Drugs 0.000 title abstract 2
- 239000006172 buffering agent Substances 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 229940127557 pharmaceutical product Drugs 0.000 title 1
- 239000011247 coating layer Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 241000208125 Nicotiana Species 0.000 abstract 1
- 235000002637 Nicotiana tabacum Nutrition 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000181 nicotinic agonist Substances 0.000 abstract 1
- 239000006186 oral dosage form Substances 0.000 abstract 1
- 239000000779 smoke Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Zoology (AREA)
- Addiction (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Obesity (AREA)
- Psychology (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Belagte orale doseringsformer for levering av nikotin i en hvilken som helst form til et subjekt ved rask intraoral levering av nikotin som innbefatter minst en kjerne, nikotin i en hvilken som helst form og/eller et nikotinetterlignende middel, minst ett belegglag og eventuelt minst ett eller flere andre additiver, hvori minst det ene belegglaget er bufret, hvorved det anvendes minst trometamol som buffer. Også omfattet er en fremgangsmåte for levering av nikotin i en hvilken som helst form, en fremgangsmåte for å redusere trangen til å røyke eller anvende tobakk så vel som en fremgangsmåte for å fremstille nevnte belagte produkt og anvendelsen av samme for å oppnå et raskt intraoralt opptak av nikotin.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0601090 | 2006-05-16 | ||
| PCT/SE2007/000365 WO2007133141A1 (en) | 2006-05-16 | 2007-04-18 | Coated pharmaceutical product for intraoral delivery of nicotine comprising trometamol as buffering agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20084987L true NO20084987L (no) | 2009-02-16 |
Family
ID=38694149
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20084987A NO20084987L (no) | 2006-05-16 | 2008-11-27 | Belagt farmasoytisk produkt for intraoral avlevering av nikotin innbefattende trometamol som bufringsmiddel |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20070269492A1 (no) |
| EP (1) | EP2023928A4 (no) |
| JP (1) | JP5254213B2 (no) |
| KR (1) | KR101414063B1 (no) |
| CN (1) | CN101472591A (no) |
| AR (1) | AR060931A1 (no) |
| AU (1) | AU2007250589B2 (no) |
| BR (1) | BRPI0712068A2 (no) |
| CA (1) | CA2652500C (no) |
| MX (1) | MX2008014726A (no) |
| NO (1) | NO20084987L (no) |
| NZ (1) | NZ572758A (no) |
| RU (1) | RU2448707C2 (no) |
| TW (1) | TW200810755A (no) |
| WO (1) | WO2007133141A1 (no) |
| ZA (1) | ZA200810618B (no) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8252321B2 (en) | 2004-09-13 | 2012-08-28 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like |
| US8642016B2 (en) | 2006-07-21 | 2014-02-04 | Jsrnti, Llc | Medicinal delivery system, and related methods |
| EP2322168A1 (en) | 2007-04-02 | 2011-05-18 | Parkinson's Institute | Methods and Compositions for Reduction of Side Effects of Therapeutic Treatments |
| GB2468424B (en) * | 2007-04-02 | 2011-11-09 | Parkinson S Inst | Methods and compositions for reduction of side effects of therapeutic treatments |
| US20080286341A1 (en) * | 2007-05-16 | 2008-11-20 | Sven-Borje Andersson | Buffered coated nicotine containing products |
| AR071420A1 (es) * | 2008-05-01 | 2010-06-16 | Smithkline Beecham Corp | Composicion de pastilla para chupar oral que comprende un principio activo de nicotina y procedimiento para fabricarla |
| AU2013219211B2 (en) * | 2008-05-01 | 2016-05-12 | North Star OpCo Limited | Nicotine lozenge compositions |
| ES2401912T3 (es) * | 2008-09-17 | 2013-04-25 | Siegfried Ltd. | Granulado que contiene nicotina |
| JP2012505878A (ja) | 2008-10-14 | 2012-03-08 | マクニール アーベー | 複数部分口内剤形及びその使用 |
| PL2198865T3 (pl) | 2008-12-19 | 2012-04-30 | Siegfried Ltd | Produkt zawierający nikotynę |
| US20100247586A1 (en) * | 2009-03-27 | 2010-09-30 | Andreas Hugerth | Multi-Portion Intra-Oral Dosage Form With Organoleptic Properties |
| WO2010145653A1 (en) * | 2009-06-19 | 2010-12-23 | Fertin Pharma A/S | Buffered gum base for high ph release |
| BR112012020731A2 (pt) * | 2010-02-18 | 2016-04-26 | Jatin Vasant Thakkar | pastilhas gelatinosas suaves com nicotina. |
| US20110268809A1 (en) | 2010-04-28 | 2011-11-03 | Paul Andrew Brinkley | Nicotine-Containing Pharmaceutical Compositions |
| US20110274628A1 (en) | 2010-05-07 | 2011-11-10 | Borschke August J | Nicotine-containing pharmaceutical compositions |
| US20130017259A1 (en) | 2011-07-06 | 2013-01-17 | The Parkinson's Institute | Compositions and Methods for Treatment of Symptoms in Parkinson's Disease Patients |
| US20130078307A1 (en) | 2011-09-22 | 2013-03-28 | Niconovum Usa, Inc. | Nicotine-containing pharmaceutical composition |
| US9474303B2 (en) | 2011-09-22 | 2016-10-25 | R.J. Reynolds Tobacco Company | Translucent smokeless tobacco product |
| US9629392B2 (en) | 2011-09-22 | 2017-04-25 | R.J. Reynolds Tobacco Company | Translucent smokeless tobacco product |
| US9084439B2 (en) | 2011-09-22 | 2015-07-21 | R.J. Reynolds Tobacco Company | Translucent smokeless tobacco product |
| US9907748B2 (en) | 2011-10-21 | 2018-03-06 | Niconovum Usa, Inc. | Excipients for nicotine-containing therapeutic compositions |
| US20130177646A1 (en) * | 2012-01-05 | 2013-07-11 | Mcneil Ab | Solid Nicotine-Comprising Dosage Form with Reduced Organoleptic Disturbance |
| US9763928B2 (en) | 2012-02-10 | 2017-09-19 | Niconovum Usa, Inc. | Multi-layer nicotine-containing pharmaceutical composition |
| US9044035B2 (en) | 2012-04-17 | 2015-06-02 | R.J. Reynolds Tobacco Company | Remelted ingestible products |
| FR2993778B1 (fr) * | 2012-07-30 | 2016-06-17 | Pf Medicament | Pastilles a cinetiques multiples de liberation de principes actifs |
| CN102926277B (zh) * | 2012-11-14 | 2015-05-20 | 湖南中烟工业有限责任公司 | 一种β-环糊精-g-乳酸共聚物的应用 |
| US9375033B2 (en) | 2014-02-14 | 2016-06-28 | R.J. Reynolds Tobacco Company | Tobacco-containing gel composition |
| JP2018511355A (ja) | 2015-01-28 | 2018-04-26 | クロノ セラピューティクス インコーポレイテッドChrono Therapeutics Inc. | 薬剤送達方法及びシステム |
| AU2016228779A1 (en) | 2015-03-12 | 2017-09-07 | Chrono Therapeutics Inc. | Craving input and support system |
| US20170172995A1 (en) * | 2015-09-08 | 2017-06-22 | Venkateswara Rao Repaka | Pharmaceutical compositions of Nicotine and process for preparation thereof |
| US20170165252A1 (en) | 2015-12-10 | 2017-06-15 | Niconovum Usa Inc. | Protein-enriched therapeutic composition |
| EP3565617A1 (en) | 2017-01-06 | 2019-11-13 | Chrono Therapeutics Inc. | Transdermal drug delivery devices and methods |
| CN111447921B (zh) * | 2017-12-08 | 2023-10-13 | 费尔廷制药公司 | 烟碱片剂 |
| EP3801732A4 (en) | 2018-05-29 | 2022-04-27 | Morningside Venture Investments Limited | METHODS AND SYSTEMS FOR DRUG DELIVERY |
| US11679081B2 (en) | 2018-07-13 | 2023-06-20 | Mcneil Ab | Chewing gum comprising nicotine |
| US12397141B2 (en) | 2018-11-16 | 2025-08-26 | Morningside Venture Investments Limited | Thermally regulated transdermal drug delivery system |
| US20230053622A1 (en) | 2020-01-15 | 2023-02-23 | Mcneil Ab | Lozenge |
| SE544672C2 (en) * | 2020-05-07 | 2022-10-11 | Liw Innovation Ab | New compositions for oral or nasal use |
| US20250041287A1 (en) * | 2021-10-21 | 2025-02-06 | Mcneil Ab | Nicotine chewing gum |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3877468A (en) * | 1970-07-22 | 1975-04-15 | Leo Ab | Chewable tobacco substitute composition |
| US3901248A (en) * | 1970-07-22 | 1975-08-26 | Leo Ab | Chewable smoking substitute composition |
| US3845217A (en) * | 1972-11-16 | 1974-10-29 | Helsingborg L Ab | Buffered smoking substitute compositions |
| GB8301659D0 (en) * | 1983-01-21 | 1983-02-23 | Leo Ab | Smoking substitutes |
| US5783207A (en) * | 1985-05-01 | 1998-07-21 | University Of Utah Research Foundation | Selectively removable nicotine-containing dosage form for use in the transmucosal delivery of nicotine |
| GB8615676D0 (en) * | 1986-06-26 | 1986-07-30 | Stoppers Co Ltd | Nicotine containing lozenge |
| US5004651A (en) * | 1989-01-24 | 1991-04-02 | Abbott Laboratories | Stabilizing system for solid dosage forms |
| US5824334A (en) * | 1989-09-05 | 1998-10-20 | University Of Utah Research Foundation | Tobacco substitute |
| US5167242A (en) * | 1990-06-08 | 1992-12-01 | Kabi Pharmacia Aktiebolaq | Nicotine-impermeable container and method of fabricating the same |
| FI943206A0 (fi) * | 1992-01-06 | 1994-07-05 | Du Pont | Tablettiformulaatio, jossa on sisäinen kuivausaine |
| SE9303574D0 (sv) * | 1993-11-01 | 1993-11-01 | Kabi Pharmacia Ab | Composition for drug delivery and method the manufacturing thereof |
| US5889028A (en) * | 1996-02-09 | 1999-03-30 | Mayo Foundation For Medical Education And Research | Colonic delivery of nicotine to treat inflammatory bowel disease |
| US5810081A (en) * | 1997-02-24 | 1998-09-22 | Cobb; Delwin E. | Wear structure for bore hole separation device |
| US6264981B1 (en) * | 1999-10-27 | 2001-07-24 | Anesta Corporation | Oral transmucosal drug dosage using solid solution |
| US20030175349A1 (en) * | 2001-01-30 | 2003-09-18 | Council Of Scientific And Industrial Research | Pharmaceutical compostion for extended/sustained release of a therapeutically active ingredient |
| SE0102197D0 (sv) * | 2001-06-20 | 2001-06-20 | Pharmacia Ab | New product and use and manufacture thereof |
| US20040037879A1 (en) * | 2001-11-02 | 2004-02-26 | Adusumilli Prasad S. | Oral controlled release forms useful for reducing or preventing nicotine cravings |
| AU2003227691B2 (en) * | 2002-05-03 | 2008-05-15 | Hexal Ag | Stable pharmaceutical formulation for a combination of a statin and an ace inhibitor |
| WO2003101431A1 (en) * | 2002-06-04 | 2003-12-11 | J.B. Chemicals & Pharmaceuticals Ltd. | Pharmaceutical composition for controlled drug delivery system |
| US20030049307A1 (en) * | 2002-08-15 | 2003-03-13 | Gyurik Robert J. | Pharmaceutical composition |
| US20040052851A1 (en) * | 2002-09-16 | 2004-03-18 | Graff Allan H. | Modified release oral dosage form |
-
2006
- 2006-06-01 US US11/444,775 patent/US20070269492A1/en not_active Abandoned
-
2007
- 2007-04-18 MX MX2008014726A patent/MX2008014726A/es active IP Right Grant
- 2007-04-18 BR BRPI0712068-0A patent/BRPI0712068A2/pt not_active Application Discontinuation
- 2007-04-18 WO PCT/SE2007/000365 patent/WO2007133141A1/en not_active Ceased
- 2007-04-18 NZ NZ572758A patent/NZ572758A/en not_active IP Right Cessation
- 2007-04-18 CA CA2652500A patent/CA2652500C/en not_active Expired - Fee Related
- 2007-04-18 EP EP07748030A patent/EP2023928A4/en not_active Withdrawn
- 2007-04-18 RU RU2008149508/15A patent/RU2448707C2/ru not_active IP Right Cessation
- 2007-04-18 AU AU2007250589A patent/AU2007250589B2/en not_active Ceased
- 2007-04-18 KR KR1020087030673A patent/KR101414063B1/ko not_active Expired - Fee Related
- 2007-04-18 CN CNA2007800232492A patent/CN101472591A/zh active Pending
- 2007-04-18 JP JP2009510917A patent/JP5254213B2/ja not_active Expired - Fee Related
- 2007-05-15 TW TW096117125A patent/TW200810755A/zh unknown
- 2007-05-15 AR ARP070102085A patent/AR060931A1/es not_active Application Discontinuation
-
2008
- 2008-11-27 NO NO20084987A patent/NO20084987L/no not_active Application Discontinuation
- 2008-12-15 ZA ZA2008/10618A patent/ZA200810618B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20090024161A (ko) | 2009-03-06 |
| TW200810755A (en) | 2008-03-01 |
| JP2009537514A (ja) | 2009-10-29 |
| ZA200810618B (en) | 2010-02-24 |
| CN101472591A (zh) | 2009-07-01 |
| AU2007250589B2 (en) | 2011-04-14 |
| MX2008014726A (es) | 2009-02-04 |
| RU2448707C2 (ru) | 2012-04-27 |
| WO2007133141A1 (en) | 2007-11-22 |
| CA2652500A1 (en) | 2007-11-22 |
| NZ572758A (en) | 2011-01-28 |
| AR060931A1 (es) | 2008-07-23 |
| BRPI0712068A2 (pt) | 2012-01-17 |
| CA2652500C (en) | 2014-07-29 |
| KR101414063B1 (ko) | 2014-07-18 |
| US20070269492A1 (en) | 2007-11-22 |
| EP2023928A4 (en) | 2012-08-29 |
| RU2008149508A (ru) | 2010-06-27 |
| AU2007250589A1 (en) | 2007-11-22 |
| JP5254213B2 (ja) | 2013-08-07 |
| EP2023928A1 (en) | 2009-02-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |