BRPI0922796A2 - Comprimido farmacêutico para administração por via oral e método de fabricação do mesmo - Google Patents

Comprimido farmacêutico para administração por via oral e método de fabricação do mesmo

Info

Publication number
BRPI0922796A2
BRPI0922796A2 BRPI0922796A BRPI0922796A BRPI0922796A2 BR PI0922796 A2 BRPI0922796 A2 BR PI0922796A2 BR PI0922796 A BRPI0922796 A BR PI0922796A BR PI0922796 A BRPI0922796 A BR PI0922796A BR PI0922796 A2 BRPI0922796 A2 BR PI0922796A2
Authority
BR
Brazil
Prior art keywords
pharmaceutical tablet
manufacturing
oral administration
weight
amount
Prior art date
Application number
BRPI0922796A
Other languages
English (en)
Inventor
Guillard Hélène
Gicquel Denis
Henrion Marianne
Gnakamene Céline
Gainer Erin
Original Assignee
Hra Pharma Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41621124&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0922796(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hra Pharma Lab filed Critical Hra Pharma Lab
Publication of BRPI0922796A2 publication Critical patent/BRPI0922796A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36—Antigestagens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

COMPRIMIDO FARMACÊUTICO PARA ADMINISTRAÇÃO POR VIA ORAL E MÉTODO DE FABRICAÇÃO DO MESMO. A invenção se refere a um comprimido farmacêutico para administrar por via oral, contendo acetato de ulipristal junto com os seguintes excipientes: pelo menos um diluente em quantidade de 50 a 98,5% em peso, pelo menos um agente aglutinante em quantidade de 0 a 10% em peso, pelo menos um agente desintegrante em quantidade de 0,5 a 10% em peso, e pelo menos um lubrificante em quantidade de 0 a 10% em peso.
BRPI0922796A 2008-12-08 2009-12-08 Comprimido farmacêutico para administração por via oral e método de fabricação do mesmo BRPI0922796A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/329,865 US8512745B2 (en) 2008-12-08 2008-12-08 Ulipristal acetate tablets
PCT/EP2009/066652 WO2010066749A2 (en) 2008-12-08 2009-12-08 Ulipristal acetate tablets

Publications (1)

Publication Number Publication Date
BRPI0922796A2 true BRPI0922796A2 (pt) 2017-07-11

Family

ID=41621124

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0922796A BRPI0922796A2 (pt) 2008-12-08 2009-12-08 Comprimido farmacêutico para administração por via oral e método de fabricação do mesmo

Country Status (28)

Country Link
US (5) US8512745B2 (pt)
EP (2) EP2365800B1 (pt)
JP (2) JP5784502B2 (pt)
KR (1) KR101733533B1 (pt)
CN (2) CN102245173A (pt)
AU (1) AU2009326084B2 (pt)
BR (1) BRPI0922796A2 (pt)
CA (1) CA2745084C (pt)
CO (1) CO6400186A2 (pt)
CY (1) CY1118099T1 (pt)
DK (1) DK2365800T3 (pt)
ES (1) ES2596554T3 (pt)
HK (1) HK1232134A1 (pt)
HR (1) HRP20161262T1 (pt)
HU (1) HUE030762T2 (pt)
IL (1) IL213247A (pt)
LT (1) LT2365800T (pt)
MX (1) MX343358B (pt)
NZ (1) NZ593498A (pt)
PL (1) PL2365800T3 (pt)
PT (1) PT2365800T (pt)
RS (1) RS55209B1 (pt)
RU (1) RU2492853C2 (pt)
SI (1) SI2365800T1 (pt)
SM (1) SMT201600372B (pt)
UA (1) UA101863C2 (pt)
WO (1) WO2010066749A2 (pt)
ZA (1) ZA201104137B (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2615475C3 (de) * 1976-04-09 1984-05-03 Philips Patentverwaltung Gmbh, 2000 Hamburg Sonnenkollektor mit einer Abdeckung aus evakuierten Rohren
JP2682237B2 (ja) 1991-01-28 1997-11-26 日産自動車株式会社 レーザー光出力装置の劣化検出装置
US8512745B2 (en) 2008-12-08 2013-08-20 Laboratoire Hra Pharma Ulipristal acetate tablets
WO2010119029A1 (en) 2009-04-14 2010-10-21 Laboratoire Hra-Pharma Method for on-demand contraception
EP2471537A1 (en) 2010-12-30 2012-07-04 PregLem S.A. Treatment of pain associated with dislocation of basal endometrium
CN102727457B (zh) * 2011-04-08 2014-05-28 华润紫竹药业有限公司 稳定的醋酸优力司特制剂
FR2987271B1 (fr) 2012-02-28 2017-08-18 Hra Pharma Lab Combinaison de modulateurs selectifs du recepteur a la progesterone et d'anti-inflammatoires non steroidiens
HUE037889T2 (hu) * 2012-05-25 2018-09-28 Hra Pharma Lab Ulipristal acetát melltumorok megelõzésére és kezelésére
FR2997627B1 (fr) * 2012-11-08 2015-01-16 Hra Pharma Lab Produit de co-micronisation comprenant de l'ulipristal acetate
FR2997628B1 (fr) * 2012-11-08 2015-01-16 Hra Pharma Lab Produit de co-micronisation comprenant un modulateur selectif des recepteurs a la progesterone
FR2999081B1 (fr) * 2012-12-06 2015-02-27 Hra Pharma Lab Dispersion solide d'un modulateur selectif du recepteur a la progesterone
CN103006595B (zh) * 2012-12-25 2018-04-06 江苏亚邦爱普森药业有限公司 制备醋酸优力司特片的方法
CN103006603B (zh) * 2013-01-11 2015-04-15 山东创新药物研发有限公司 醋酸乌利司他的固体分散体及固体制剂
CN103083326A (zh) * 2013-02-04 2013-05-08 四川尚锐生物医药有限公司 一种醋酸优力司特药物组合物
KR20150139919A (ko) * 2013-04-10 2015-12-14 쁘레글렘 에스아 자궁 섬유종의 치료에서 사용하기 위한 프로게스테론 수용체 조절제
CN104865215A (zh) * 2015-05-16 2015-08-26 南京海纳医药科技有限公司 一种醋酸乌利司他片剂及其溶出度测定方法
FR3060389B1 (fr) 2016-12-20 2019-05-31 Laboratoire Hra-Pharma Comprime enrobe comprenant de l'ulipristal acetate ou un de ses metabolites
WO2017216637A2 (en) 2017-08-04 2017-12-21 Alvogen Malta Operations (Row) Ltd Tablet form including ulipristal acetate and the methods for its preparation
CN107982230A (zh) * 2017-12-25 2018-05-04 郑州泰丰制药有限公司 一种醋酸乌利司他分散片及其制备方法
CN114137115B (zh) * 2021-11-26 2023-08-04 四川尚锐分析检测有限公司 一种采用lc-ms法检测血浆中醋酸优力司特及其代谢物的方法

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Publication number Priority date Publication date Assignee Title
US4954490A (en) 1988-06-23 1990-09-04 Research Triangle Institute 11 β-substituted progesterone analogs
US5084277A (en) * 1988-08-30 1992-01-28 Greco John C Vaginal progesterone tablet
ZA939565B (en) 1993-12-21 1994-08-11 Applied Analytical Ind Inc Method for preparing low dose pharmaceutical products.
US5759577A (en) * 1995-01-17 1998-06-02 American Home Products Corporation Controlled release of steroids from sugar coatings
US5929262A (en) 1995-03-30 1999-07-27 The United States Of America As Represented By The Department Of Health And Human Services Method for preparing 17α-acetoxy-11β-(4-N, N-dimethylaminophyl)-19-Norpregna-4,9-diene-3, 20-dione, intermediates useful in the method, and methods for the preparation of such intermediates
HU227198B1 (en) 2001-11-27 2010-10-28 Richter Gedeon Nyrt Pharmaceutical composition for emergency contraception containing levonorgestrel
ES2212912B1 (es) 2003-01-22 2005-10-01 Crystal Pharma, S.A. Procedimiento para la obtencion de 17alfa-acetoxi-11beta-(4-n,n-dimetilaminofenil)-19-norpregna-4,9-dien-3,20-diona.
AU2004217988C1 (en) 2003-02-28 2010-06-03 Southwest Foundation For Biomedical Research Method for preparing 17 alpha-acetoxy-11beta-(4-N,N-dimethylaminophenyl)-19-norpregna-4,9-diene-3,20-dione, intermediates thereof, and methods for the preparation of such intermediates
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BRPI0610438A2 (pt) 2005-04-28 2012-10-23 Wyeth Corp composição farmacêutica, cápsula, conjunto farmacêutico, e, processo para preparar uma composição
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SI2148681T1 (sl) 2007-04-20 2016-07-29 Preglem S.A. Selektivni modulatorji progesterona v zdravljenju maternične krvavitve
US20090117184A1 (en) 2007-11-05 2009-05-07 Sabine Fricke Use of a gestagen in combination with an estrogen and one or more pharmaceutically acceptable auxiliary agents/excipients for lactose-free oral contraception
US8512745B2 (en) * 2008-12-08 2013-08-20 Laboratoire Hra Pharma Ulipristal acetate tablets

Also Published As

Publication number Publication date
CN102245173A (zh) 2011-11-16
US8512745B2 (en) 2013-08-20
DK2365800T3 (en) 2016-10-24
SMT201600372B (it) 2017-01-10
JP2015107994A (ja) 2015-06-11
JP6151727B2 (ja) 2017-06-21
US20140228335A1 (en) 2014-08-14
EP2365800B1 (en) 2016-07-20
CA2745084C (en) 2014-11-18
CN105267168A (zh) 2016-01-27
SI2365800T1 (sl) 2017-01-31
IL213247A (en) 2015-07-30
EP3103445A1 (en) 2016-12-14
HRP20161262T1 (hr) 2016-12-16
HUE030762T2 (en) 2017-05-29
KR101733533B1 (ko) 2017-05-10
MX2011006106A (es) 2011-06-24
NZ593498A (en) 2012-07-27
CO6400186A2 (es) 2012-03-15
UA101863C2 (uk) 2013-05-13
RU2492853C2 (ru) 2013-09-20
US20180064651A1 (en) 2018-03-08
US20100144692A1 (en) 2010-06-10
JP2012511041A (ja) 2012-05-17
US20160287518A1 (en) 2016-10-06
CY1118099T1 (el) 2017-06-28
RU2011127989A (ru) 2013-01-20
PT2365800T (pt) 2016-10-25
JP5784502B2 (ja) 2015-09-24
ZA201104137B (en) 2012-02-29
AU2009326084B2 (en) 2014-06-05
PL2365800T3 (pl) 2017-03-31
ES2596554T3 (es) 2017-01-10
RS55209B1 (sr) 2017-01-31
WO2010066749A3 (en) 2010-08-05
US8735380B2 (en) 2014-05-27
WO2010066749A2 (en) 2010-06-17
US9844510B2 (en) 2017-12-19
LT2365800T (lt) 2016-11-10
IL213247A0 (en) 2011-07-31
MX343358B (es) 2016-11-03
AU2009326084A1 (en) 2011-07-07
US20120077790A1 (en) 2012-03-29
CA2745084A1 (en) 2010-06-17
EP2365800A2 (en) 2011-09-21
KR20110097936A (ko) 2011-08-31
HK1232134A1 (en) 2018-01-05

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B06T Formal requirements before examination [chapter 6.20 patent gazette]
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