NO20085257L - Purinonderivater som HM74a-agonister - Google Patents

Purinonderivater som HM74a-agonister

Info

Publication number
NO20085257L
NO20085257L NO20085257A NO20085257A NO20085257L NO 20085257 L NO20085257 L NO 20085257L NO 20085257 A NO20085257 A NO 20085257A NO 20085257 A NO20085257 A NO 20085257A NO 20085257 L NO20085257 L NO 20085257L
Authority
NO
Norway
Prior art keywords
purinone derivatives
hm74a agonists
agonists
purinone
derivatives
Prior art date
Application number
NO20085257A
Other languages
English (en)
Inventor
Brian Metcalf
Anlai Wang
Chu-Biao Xue
Changsheng Zheng
Ganfeng Cao
Michael Xia
Hai Fen Ye
Original Assignee
Incyte Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Corp filed Critical Incyte Corp
Publication of NO20085257L publication Critical patent/NO20085257L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Foreliggende oppfinnelse angår purinonderivater som er agonister av HM74areseptoren. Videre tilveiebringes det preparater og metoder for anvendelse av forbindelsene her og deres farmasøytisk akseptable salter for behandling av sykdom.
NO20085257A 2006-06-23 2008-12-16 Purinonderivater som HM74a-agonister NO20085257L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81595506P 2006-06-23 2006-06-23
US92281807P 2007-04-11 2007-04-11
PCT/US2007/071891 WO2007150025A2 (en) 2006-06-23 2007-06-22 Purinone derivatives as hm74a agonists

Publications (1)

Publication Number Publication Date
NO20085257L true NO20085257L (no) 2009-01-19

Family

ID=38721463

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20085257A NO20085257L (no) 2006-06-23 2008-12-16 Purinonderivater som HM74a-agonister

Country Status (14)

Country Link
US (4) US7511050B2 (no)
EP (1) EP2044074A2 (no)
JP (1) JP5584466B2 (no)
KR (1) KR20090025261A (no)
CN (1) CN101466714B (no)
AR (1) AR061625A1 (no)
AU (1) AU2007260851B2 (no)
BR (1) BRPI0713619A2 (no)
CA (1) CA2656039A1 (no)
IL (1) IL195904A0 (no)
MX (1) MX2009000170A (no)
NO (1) NO20085257L (no)
TW (1) TWI423977B (no)
WO (1) WO2007150025A2 (no)

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SE0302756D0 (sv) * 2003-10-17 2003-10-17 Astrazeneca Ab Novel Compounds
AR061626A1 (es) * 2006-06-23 2008-09-10 Incyte Corp Derivados de purinona como agonistas de hm74a
US7511050B2 (en) * 2006-06-23 2009-03-31 Incyte Corporation Purinone derivatives as HM74A agonists
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
KR101799429B1 (ko) 2010-05-03 2017-11-21 에스케이바이오팜 주식회사 신경 세포 사멸 또는 신경 퇴화를 억제하기 위한 약학적 조성물
EP2582709B1 (de) 2010-06-18 2018-01-24 Sanofi Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2760862B1 (en) 2011-09-27 2015-10-21 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP3490579B1 (en) 2016-07-27 2025-09-10 Hartis-Pharma SA Therapeutic combinations to treat red blood cell disorders
AR112457A1 (es) * 2017-08-02 2019-10-30 Lilly Co Eli Derivados de [1,2,4]triazolo[4,3-a]pirazin-6(5h)-ona
CU20200038A7 (es) 2017-10-27 2021-03-11 Bayer Ag Compuestos derivados de pirazolo-pirrolo-pirimidina-diona como inhibidores de p2x3
AU2019227607C1 (en) 2018-02-27 2023-07-20 Incyte Corporation Imidazopyrimidines and triazolopyrimidines as A2A / A2B inhibitors
US11220510B2 (en) 2018-04-09 2022-01-11 Incyte Corporation Pyrrole tricyclic compounds as A2A / A2B inhibitors
EP3810610A1 (en) 2018-05-18 2021-04-28 Incyte Corporation Fused pyrimidine derivatives as a2a / a2b inhibitors
CN117304191A (zh) 2018-07-05 2023-12-29 因赛特公司 作为a2a/a2b抑制剂的稠合吡嗪衍生物
TWI829857B (zh) 2019-01-29 2024-01-21 美商英塞特公司 作為a2a / a2b抑制劑之吡唑并吡啶及三唑并吡啶

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CA1095906A (en) * 1977-02-14 1981-02-17 Davis L. Temple, Jr. Heterocyclopyrimidines, compositions and therapeutic process
BE863525A (fr) 1977-02-14 1978-07-31 Bristol Myers Co Heterocyclopyrimidines
US4404380A (en) * 1977-02-14 1983-09-13 Mead Johnson & Company Triazolopyrimidines
AU3869789A (en) * 1988-07-21 1990-02-19 Upjohn Company, The Pyrazolo-pyrrolo-pyrimidine-diones
JP2980658B2 (ja) 1989-09-14 1999-11-22 協和醗酵工業株式会社 ｓ―トリアゾロ〔３，４―ｉ〕プリン誘導体
JPH083168A (ja) * 1994-06-15 1996-01-09 Yamasa Shoyu Co Ltd ４−メチル−９Ｈ−イミダゾ［１，２−ａ］プリン−９−オン類
JP3204879B2 (ja) 1995-08-04 2001-09-04 オリエンタル酵母工業株式会社 パン用酵母の包装紙
EP0879183A1 (fr) 1996-07-18 1998-11-25 Montania Bouchon avec recipient auxiliaire et procede de realisation
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US8143264B2 (en) 2005-08-10 2012-03-27 Glaxosmithkline Llc Xanthine derivatives as selective HM74A agonists
GB0516462D0 (en) 2005-08-10 2005-09-14 Smithkline Beecham Corp Novel compounds
AR061626A1 (es) 2006-06-23 2008-09-10 Incyte Corp Derivados de purinona como agonistas de hm74a
US7511050B2 (en) * 2006-06-23 2009-03-31 Incyte Corporation Purinone derivatives as HM74A agonists

Also Published As

Publication number Publication date
WO2007150025A3 (en) 2008-02-07
TWI423977B (zh) 2014-01-21
AU2007260851B2 (en) 2013-01-17
JP5584466B2 (ja) 2014-09-03
MX2009000170A (es) 2009-01-23
AR061625A1 (es) 2008-09-10
US20090286774A1 (en) 2009-11-19
US7511050B2 (en) 2009-03-31
US20120035172A1 (en) 2012-02-09
CA2656039A1 (en) 2007-12-27
AU2007260851A1 (en) 2007-12-27
TW200813064A (en) 2008-03-16
US8703783B2 (en) 2014-04-22
US20080045554A1 (en) 2008-02-21
US20140371216A1 (en) 2014-12-18
KR20090025261A (ko) 2009-03-10
EP2044074A2 (en) 2009-04-08
BRPI0713619A2 (pt) 2013-01-15
IL195904A0 (en) 2009-09-01
US8039478B2 (en) 2011-10-18
CN101466714A (zh) 2009-06-24
CN101466714B (zh) 2013-02-06
JP2009541355A (ja) 2009-11-26
WO2007150025A2 (en) 2007-12-27

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