NO20085332L - Duloksetinhydrogenklorid-formuleringer med forsinket frigivelse - Google Patents

Duloksetinhydrogenklorid-formuleringer med forsinket frigivelse

Info

Publication number
NO20085332L
NO20085332L NO20085332A NO20085332A NO20085332L NO 20085332 L NO20085332 L NO 20085332L NO 20085332 A NO20085332 A NO 20085332A NO 20085332 A NO20085332 A NO 20085332A NO 20085332 L NO20085332 L NO 20085332L
Authority
NO
Norway
Prior art keywords
hydrogen chloride
delayed release
duloxetine
chloride formulations
layer
Prior art date
Application number
NO20085332A
Other languages
English (en)
Inventor
Gershon Kolatkar
Erela Zisman
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma filed Critical Teva Pharma
Publication of NO20085332L publication Critical patent/NO20085332L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Formuleringer med forsinket frigivelse av duloksetinhydrogenklorid og fremgangsmåter for fremstilling av slike er beskrevet. En foretrukket formulering innbefatter en inert kjerne, et legemiddellag omfattende duloksetinhydrogenklorid, et skillelag og et enterisk lag som omfatter minst én av metakrylsyrekopolymer og hydroksypropylmetylcelluloseftalat.
NO20085332A 2006-05-22 2008-12-19 Duloksetinhydrogenklorid-formuleringer med forsinket frigivelse NO20085332L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80284906P 2006-05-22 2006-05-22
PCT/US2007/012387 WO2007139886A2 (en) 2006-05-22 2007-05-22 Duloxetine hydrochloride delayed release formulations

Publications (1)

Publication Number Publication Date
NO20085332L true NO20085332L (no) 2008-12-19

Family

ID=38779216

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20085332A NO20085332L (no) 2006-05-22 2008-12-19 Duloksetinhydrogenklorid-formuleringer med forsinket frigivelse

Country Status (12)

Country Link
US (1) US20070292511A1 (no)
EP (1) EP1919467A2 (no)
JP (1) JP2009538315A (no)
KR (1) KR20090005237A (no)
CN (1) CN101448493A (no)
BR (1) BRPI0711606A2 (no)
CA (1) CA2651716A1 (no)
IL (1) IL194877A0 (no)
MX (1) MX2008014758A (no)
NO (1) NO20085332L (no)
RU (1) RU2008148547A (no)
WO (1) WO2007139886A2 (no)

Families Citing this family (38)

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US20090175935A1 (en) * 2006-08-14 2009-07-09 Torrent Research Ltd. Pharmaceutical compositions of duloxetine
WO2009004649A2 (en) * 2007-05-21 2009-01-08 Sun Pharmaceutical Industries Limited Enteric coated pharmaceutical compositions
GB0712220D0 (en) * 2007-06-23 2007-08-01 Arrow Int Ltd Duloxetine formulation
WO2009066181A2 (en) * 2007-07-09 2009-05-28 Combino Pharm, S.L. Oral delayed-release duloxentine hydrochloride pellets
CL2008002032A1 (es) * 2007-07-13 2009-01-23 Synthon Bv Forma de dosis farmaceutica que posee una pluralidad de pellets, cada pellet comprende, un nucleo de pellet con un diametro de 600 a 1000 micrometros, capa de farmaco que comprende duloxetina o una sal y aglutinante de preferencia metil celulosa, una capa de separacion y una capa de recubrimiento enterico; proceso de preparacion
CN101939004A (zh) * 2008-01-25 2011-01-05 阿尔法制药有限公司 度洛西汀的缓释药物组合物
US20110020439A1 (en) * 2008-03-24 2011-01-27 Shrenik Annasaheb Kole Delayed release compositions of duloxetine
US20110150942A1 (en) * 2008-06-13 2011-06-23 Natalija Zajc Gastro-resistant pharmaceutical oral compositions comprising duloxetine or its pharmaceutically acceptable derivatives
EP2133072A1 (en) 2008-06-13 2009-12-16 KRKA, D.D., Novo Mesto Gastro-resistant pharmaceutical oral compositions comprising duloxetine or its pharmaceutically acceptable derivatives
US20100040680A1 (en) * 2008-08-15 2010-02-18 Felix Lai Multiparticulate selective serotonin and norepinephrine reuptake inhibitor formulation
ES2376095B1 (es) * 2008-10-02 2013-01-24 Laboratorios Del Dr. Esteve, S.A. Pellets entéricos de duloxetina.
WO2010078878A1 (en) * 2009-01-12 2010-07-15 Synthon B.V. Duloxetine formulations
DE102009033621A1 (de) 2009-07-17 2011-01-20 Add Technologies Ltd. Trennschichten für pharmazeutische Zubereitungen zur Verhinderung von Wechselwirkungen zwischen Arzneistoffen und pharmazeutisch-technologischen Hilfsstoffen
MX339408B (es) * 2010-03-09 2016-05-24 Alkermes Pharma Ireland Ltd Composiciones farmaceuticas entericas resistentes al alcohol.
EP2377525A1 (en) 2010-03-26 2011-10-19 Laboratorios del Dr. Esteve S.A. Duloxetine enteric pellets
WO2013045352A1 (de) * 2011-09-30 2013-04-04 Basf Se Verfahren zur herstellung von festen pigmenthaltigen filmüberzugsmitteln in form von granulaten auf basis von magensaftresistenten filmbildnern für pharmazeutische dosierungsformen
US9801820B2 (en) 2012-11-12 2017-10-31 New Jersey Institute Of Technology Pharmaceutical core-shell composite powder and processes for making the same
CN103127023B (zh) * 2013-03-01 2014-08-27 河北天成药业股份有限公司 一种盐酸度洛西汀肠溶片及其制备方法
CN103211777A (zh) * 2013-03-31 2013-07-24 北京万全阳光医学技术有限公司 一种盐酸度洛西汀的药物制剂及其制备的方法
CN103393615B (zh) * 2013-07-24 2015-07-15 海南华益泰康药业有限公司 一种度洛西汀肠溶小丸及其制备方法
PL224543B1 (pl) 2013-08-21 2017-01-31 Pabianickie Zakłady Farm Polfa Spółka Akcyjna Dojelitowa tabletka duloksetyny
JP6815109B2 (ja) * 2016-06-23 2021-01-20 キョーリンリメディオ株式会社 デュロキセチンまたは薬学的に許容されるその塩を有効成分とする医薬組成物
JP6866136B2 (ja) * 2016-11-30 2021-04-28 共和薬品工業株式会社 デュロキセチン塩酸塩を含む口腔内崩壊錠
US9839626B1 (en) 2016-12-14 2017-12-12 Sun Pharmaceutical Industries Limited Duloxetine sprinkles
JP2018154590A (ja) * 2017-03-17 2018-10-04 沢井製薬株式会社 デュロキセチン腸溶性顆粒およびデュロキセチン腸溶性製剤
JP7072431B2 (ja) * 2017-04-14 2022-05-20 富士化学工業株式会社 錠剤及びその製造方法
JP6972674B2 (ja) * 2017-06-06 2021-11-24 ニプロ株式会社 経口医薬製剤
BR112020000011A2 (pt) 2017-07-11 2020-07-21 Qualicaps Co., Ltd. cápsula dura entérica
JP2019081753A (ja) * 2017-10-30 2019-05-30 大原薬品工業株式会社 デュロキセチン塩酸塩の溶出性が改善された腸溶性製剤
US10765635B2 (en) * 2018-02-06 2020-09-08 Nano Pharmaceutical Laboratories Llc Multiparticulate including pharmaceutical or probiotic active ingredients for delivery via a shelf stable liquid dosage form
KR20210022716A (ko) 2018-06-22 2021-03-03 쿠오리카프스 가부시키가이샤 장용성 경질 캡슐
JP2020029447A (ja) * 2018-06-25 2020-02-27 大原薬品工業株式会社 腸溶性高分子及び抗付着剤を含有する顆粒
RS61368B1 (sr) * 2018-09-27 2021-02-26 Inibsa Ginecologia S A Postupak za pripremu višejediničnog oralnog doznog oblika sa modifikovanim oslobađanjem doksilamin sukcinata i piridoksin hidrohlorida
CN112168797A (zh) * 2020-10-14 2021-01-05 宁波高新区美诺华医药创新研究院有限公司 度洛西汀药物组合物
WO2022115054A1 (en) * 2020-11-27 2022-06-02 Santa Farma Ilac Sanayii A.S. Enteric coated duloxetine compositions
KR20230174213A (ko) * 2021-03-09 2023-12-27 엔사이스 바이오사이언시즈 인크. 나파모스타트의 변형된 방출 조성물 및 그의 사용 방법
IL305493A (en) 2021-03-09 2023-10-01 Ensysce Biosciences Inc Compositions comprising enzyme-cleavable prodrugs and controlled release nafamostat and methods of use thereof
CN121003600A (zh) * 2024-05-22 2025-11-25 广州帝奇医药技术有限公司 度洛西汀肠溶微丸及复方制剂和制备方法

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US20070141150A1 (en) * 2003-12-30 2007-06-21 Raghupathi Kandarapu Pharmaceutical composition
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US20100285123A1 (en) * 2005-06-20 2010-11-11 Rudresha Korlakunte Virupakshalah Prasad Controlled Release Dosage Formulation of Duloxetine
US20060165776A1 (en) * 2005-08-31 2006-07-27 Ramesh Sesha Antidepressant oral pharmaceutical compositions

Also Published As

Publication number Publication date
EP1919467A2 (en) 2008-05-14
IL194877A0 (en) 2009-08-03
BRPI0711606A2 (pt) 2012-02-14
WO2007139886A2 (en) 2007-12-06
KR20090005237A (ko) 2009-01-12
CN101448493A (zh) 2009-06-03
RU2008148547A (ru) 2010-06-27
WO2007139886A3 (en) 2008-03-13
US20070292511A1 (en) 2007-12-20
CA2651716A1 (en) 2007-12-06
MX2008014758A (es) 2009-01-19
JP2009538315A (ja) 2009-11-05

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