NO20090166L - Amino-imidazoloner og deres anvendelse som et medikament for behandling av kognitiv svekkelse, Alzheimers sykdom, neurodegenerering og demens - Google Patents

Amino-imidazoloner og deres anvendelse som et medikament for behandling av kognitiv svekkelse, Alzheimers sykdom, neurodegenerering og demens

Info

Publication number
NO20090166L
NO20090166L NO20090166A NO20090166A NO20090166L NO 20090166 L NO20090166 L NO 20090166L NO 20090166 A NO20090166 A NO 20090166A NO 20090166 A NO20090166 A NO 20090166A NO 20090166 L NO20090166 L NO 20090166L
Authority
NO
Norway
Prior art keywords
neurodegeneration
dementia
alzheimer
disease
treatment
Prior art date
Application number
NO20090166A
Other languages
English (en)
Norwegian (no)
Inventor
Stefan Berg
Niklas Plobeck
Didier Rotticci
Katharina Hogdin
Karin Kolmodin
Jorg Holenz
Fernando Sehgelmeble
Original Assignee
Astex Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38831994&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20090166(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astex Therapeutics Ltd filed Critical Astex Therapeutics Ltd
Publication of NO20090166L publication Critical patent/NO20090166L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO20090166A 2006-06-14 2009-01-12 Amino-imidazoloner og deres anvendelse som et medikament for behandling av kognitiv svekkelse, Alzheimers sykdom, neurodegenerering og demens NO20090166L (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US81354906P 2006-06-14 2006-06-14
US86645106P 2006-11-20 2006-11-20
US89698607P 2007-03-26 2007-03-26
PCT/SE2007/000573 WO2007145570A1 (en) 2006-06-14 2007-06-12 Amino-imidazolones and their use as a medicament for treating cognitive impairment, alzheimer disease, neurodegeneration and dementia

Publications (1)

Publication Number Publication Date
NO20090166L true NO20090166L (no) 2009-03-12

Family

ID=38831994

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20090166A NO20090166L (no) 2006-06-14 2009-01-12 Amino-imidazoloner og deres anvendelse som et medikament for behandling av kognitiv svekkelse, Alzheimers sykdom, neurodegenerering og demens

Country Status (16)

Country Link
US (1) US20070299087A1 (pt)
EP (1) EP2035425A1 (pt)
JP (1) JP2009539975A (pt)
KR (1) KR20090031564A (pt)
AR (1) AR061371A1 (pt)
AU (1) AU2007259432A1 (pt)
BR (1) BRPI0712731A2 (pt)
CA (1) CA2654403A1 (pt)
CL (1) CL2007001732A1 (pt)
EC (1) ECSP088969A (pt)
IL (1) IL195574A0 (pt)
MX (1) MX2008015587A (pt)
NO (1) NO20090166L (pt)
TW (1) TW200808796A (pt)
UY (1) UY30411A1 (pt)
WO (1) WO2007145570A1 (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7700603B2 (en) * 2003-12-15 2010-04-20 Schering Corporation Heterocyclic aspartyl protease inhibitors
US7763609B2 (en) 2003-12-15 2010-07-27 Schering Corporation Heterocyclic aspartyl protease inhibitors
US7592348B2 (en) 2003-12-15 2009-09-22 Schering Corporation Heterocyclic aspartyl protease inhibitors
WO2006014944A1 (en) * 2004-07-28 2006-02-09 Schering Corporation Macrocyclic beta-secretase inhibitors
CN101228163A (zh) * 2005-06-14 2008-07-23 先灵公司 天冬氨酰蛋白酶抑制剂
CA2610828A1 (en) * 2005-06-14 2006-12-28 Schering Corporation Heterocyclic aspartyl protease inhibitors, preparation and use thereof
TW200815349A (en) 2006-06-22 2008-04-01 Astrazeneca Ab New compounds
JP2010512389A (ja) 2006-12-12 2010-04-22 シェーリング コーポレイション アスパルチルプロテアーゼ阻害剤
KR20090090364A (ko) * 2006-12-12 2009-08-25 쉐링 코포레이션 트리사이클릭 환 시스템을 함유하는 아스파르틸 프로테아제 억제제
CL2009000954A1 (es) * 2008-04-22 2010-12-31 Schering Corp Compuestos derivados de 2-imino-3-metil pirrolo pirimidinona,inhibidores de bace-1; composicion farmaceutica; y su uso para tratar, prevenir y/o retardar el inicio de una patologia de beta-amiloide seleccionada de enfermedad de alzheimer, enfermedad de parkinson, perdida de la memoria, sindrome de down, entre otras.
US20100125087A1 (en) * 2008-11-14 2010-05-20 Astrazeneca Ab New compounds 575
US20100125081A1 (en) * 2008-11-14 2010-05-20 Astrazeneca Ab New compounds 574
TW201020244A (en) 2008-11-14 2010-06-01 Astrazeneca Ab New compounds
CA2754416A1 (en) * 2009-03-26 2010-09-30 Dainippon Sumitomo Pharma Co., Ltd. Novel medicament for treating cognitive impairment
WO2011044187A1 (en) 2009-10-08 2011-04-14 Schering Corporation Iminothiadiazine dioxide compounds as bace inhibitors, compositions, and their use
WO2011044185A2 (en) 2009-10-08 2011-04-14 Schering Corporation Pentafluorosulfur imino heterocyclic compounds as bace-1 inhibitors, compositions, and their use
WO2011044184A1 (en) 2009-10-08 2011-04-14 Schering Corporation Pentafluorosulfur imino heterocyclic compounds as bace-1 inhibitors, compositions, and their use
UA108363C2 (uk) 2009-10-08 2015-04-27 Похідні імінотіадіазиндіоксиду як інгібітори bace, композиція на їх основі і їх застосування
US9145426B2 (en) 2011-04-07 2015-09-29 Merck Sharp & Dohme Corp. Pyrrolidine-fused thiadiazine dioxide compounds as BACE inhibitors, compositions, and their use
WO2012138734A1 (en) 2011-04-07 2012-10-11 Merck Sharp & Dohme Corp. C5-c6 oxacyclic-fused thiadiazine dioxide compounds as bace inhibitors, compositions, and their use
KR20140054295A (ko) 2011-08-22 2014-05-08 머크 샤프 앤드 돔 코포레이션 Bace 억제제로서의 2-스피로-치환된 이미노티아진 및 그의 모노- 및 디옥시드, 조성물 및 그의 용도
USRE49873E1 (en) 2012-03-19 2024-03-19 Buck Institute For Research On Aging APP specific bace inhibitors (ASBIs) and uses thereof
EP2908825B1 (en) 2012-10-17 2018-04-18 Merck Sharp & Dohme Corp. Tricyclic substituted thiadiazine dioxide compounds as bace inhibitors, compositions, and their use
WO2014062553A1 (en) 2012-10-17 2014-04-24 Merck Sharp & Dohme Corp. Tricyclic substituted thiadiazine dioxide compounds as bace inhibitors, compositions, and their use
WO2014127042A1 (en) 2013-02-12 2014-08-21 Buck Institute For Research On Aging Hydantoins that modulate bace-mediated app processing

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE423121T1 (de) * 2004-06-16 2009-03-15 Wyeth Corp Diphenylimidazopyrimidin- und -imidazolamine als b-sekretase-inhibitoren
CN101103034A (zh) * 2005-01-14 2008-01-09 惠氏公司 抑制β-分泌酶的氨基-咪唑酮

Also Published As

Publication number Publication date
TW200808796A (en) 2008-02-16
EP2035425A1 (en) 2009-03-18
WO2007145570A1 (en) 2007-12-21
US20070299087A1 (en) 2007-12-27
AU2007259432A1 (en) 2007-12-21
IL195574A0 (en) 2009-09-01
BRPI0712731A2 (pt) 2012-10-02
UY30411A1 (es) 2008-01-31
WO2007145570A9 (en) 2008-12-11
ECSP088969A (es) 2009-01-30
AR061371A1 (es) 2008-08-20
CL2007001732A1 (es) 2008-01-25
CA2654403A1 (en) 2007-12-21
JP2009539975A (ja) 2009-11-19
KR20090031564A (ko) 2009-03-26
MX2008015587A (es) 2009-01-09

Similar Documents

Publication Publication Date Title
NO20090755L (no) Amino-imidazoloner og deres anvendelse som et medikament for behandling av kognitiv svekkelse, Alzheimers sykdom, neurodegenerering og demens
NO20090246L (no) Substituerte isoindoler som bace-inhibitorer og deres anvendelse
NO20082673L (no) Nye 2-amino-imidazol-4-on forbindelser og deres anvendelse i fremstilling av et medikament som skal brukes til behandling av kognitiv svekkelse, Alzheimers sykdom, neurodegenerasjon og demens
NO20082481L (no) Nye 2-aminoheterosykluser som er nyttige ved behandling av ABETA-relaterte patologier
ECSP099755A (es) Derivados de pirrolopiridina y su uso como inhibidores de bace
NO20083197L (no) Substituert cinnolin-derivater som GABAA-reseptor modulatorer og metode for deres syntese
NO20081315L (no) Benzokinazolinderivater og deres anvendelse ved behandling av benlidelser
NO20084516L (no) Terfenylderivater for behandling av alzheimers sykdom
EA200900136A1 (ru) Пирролопиримидины для фармацевтических композиций
WO2008076046A8 (en) Novel 2-amino-5, 5-diaryl-imidazol-4-ones
NO20083918L (no) Dihydridiazepiner anvendelige som inhibitorer av proteinkinaser
NO20085323L (no) Smeltede, tricykliske sulfonamidinhibitorer av gammasekretase
PH12012501122A1 (en) Pteridinones as inhibitors of polo-like kinase
NZ598242A (en) Triazolopyridine compound, and action thereof as prolyl hydroxylase inhibitor and erythropoietin production inducer
ECSP088969A (es) Amino-imidazolones y su uso como medicamento para tratar deficiencias cognitivas, enfermedad de alzheimer, neurodegeneración y demencia
NO20080981L (no) Nitrocatechol-derivater som COMT-inhibitorer
CR20200286A (es) DERIVADOS DE DIHIDRO-BENZO-OXAZINA Y DIHIDRO-PIRIDO-OXAZINA (Divisional 2014-0294)
DK2150530T3 (da) Substituerede sulfonamid-derivater
NO20082096L (no) Azaindol-2-karboksamidderivativer
NO20083708L (no) 4-Fenyl-tiazol-5-karboksylsyre og 4-fenyl-tiazol-5-karboksylmider som PLK1-inhibitorer
UY30414A1 (es) Metano sulfonatos, propano-1-sulfonatos y ciclopropan sulfonatos sustituidos con [2,3,4,8-tetrahidroimidazo-[1,5-al-pirimidin-8-il]-fenilo, composiciones farmacéuticas conteniéndolos y aplicaciones.
NO20080394L (no) N-(arylalkyl)-1H-pyrrolopyridin-2-karboksamidderivater, fremstilling og anvendelse derav
NO20084301L (no) Tetrahydronaftalenderivater, fremgangsmate for deres fremstilling og anvendelse derav som anti-inflammatoriske midler
PH12015500012A1 (en) Benzodioxole derivative and preparation method and use thereof
NO20064659L (no) Nye kvarterniserte quinuklidin-estere

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application