NO20064659L - Nye kvarterniserte quinuklidin-estere - Google Patents

Nye kvarterniserte quinuklidin-estere

Info

Publication number
NO20064659L
NO20064659L NO20064659A NO20064659A NO20064659L NO 20064659 L NO20064659 L NO 20064659L NO 20064659 A NO20064659 A NO 20064659A NO 20064659 A NO20064659 A NO 20064659A NO 20064659 L NO20064659 L NO 20064659L
Authority
NO
Norway
Prior art keywords
compounds
new
quinuclidine esters
urological
respiratory
Prior art date
Application number
NO20064659A
Other languages
English (en)
Inventor
Maria Dolors Fernandez Forner
Maria Prat Quinones
Maria Antonia Buil Albero
Original Assignee
Almirall Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Almirall Lab filed Critical Almirall Lab
Publication of NO20064659L publication Critical patent/NO20064659L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Otolaryngology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Nye kinuklidinderivater og farmasøytiske sammensetninger omfattende disse. Forbindelser med formel (I), hvori de ulike substituenter og/eller radikaler har verdiene definert i kravene. Oppfinnelsen angår også en fremgangsmåte for fremstilling av nevnte forbindelser, til farmasøytiske sammensetninger som omfatter disse, så vel som til kombinasjoner av nevnte forbindelser med andre forbindelser, som er aktive i behandlingen av respiratorisk, urologisk eller gastrointestinale forstyrrelser eller sykdommer. Endelig angår oppfinnelsen også anvendelse av forbindelsene med formel (I) for behandling av respiratoriske, urologiske eller gasttointestinale forstyrrelser eller sykdommer.
NO20064659A 2004-03-15 2006-10-13 Nye kvarterniserte quinuklidin-estere NO20064659L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200400638A ES2239546B1 (es) 2004-03-15 2004-03-15 Nuevos esteres de quinuclidina cuaternizados.
PCT/EP2005/002523 WO2005090342A1 (en) 2004-03-15 2005-03-10 New quaternized quinuclidine esters

Publications (1)

Publication Number Publication Date
NO20064659L true NO20064659L (no) 2006-12-13

Family

ID=34955916

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20064659A NO20064659L (no) 2004-03-15 2006-10-13 Nye kvarterniserte quinuklidin-estere

Country Status (30)

Country Link
US (1) US20080214600A1 (no)
EP (1) EP1725552B1 (no)
JP (1) JP2007529444A (no)
KR (1) KR20070003940A (no)
CN (1) CN1930158A (no)
AR (1) AR048004A1 (no)
AT (1) ATE399166T1 (no)
AU (1) AU2005223310A1 (no)
BR (1) BRPI0508177A (no)
CA (1) CA2560157A1 (no)
CY (1) CY1108324T1 (no)
DE (1) DE602005007714D1 (no)
DK (1) DK1725552T3 (no)
EC (1) ECSP066770A (no)
ES (2) ES2239546B1 (no)
HR (1) HRP20080338T3 (no)
IL (1) IL177341A0 (no)
MY (1) MY142036A (no)
NO (1) NO20064659L (no)
NZ (1) NZ548583A (no)
PE (1) PE20060005A1 (no)
PL (1) PL1725552T3 (no)
PT (1) PT1725552E (no)
RS (1) RS50566B (no)
RU (1) RU2382041C2 (no)
SI (1) SI1725552T1 (no)
TW (1) TW200604196A (no)
UA (1) UA88634C2 (no)
WO (1) WO2005090342A1 (no)
ZA (1) ZA200605931B (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
GB0424284D0 (en) * 2004-11-02 2004-12-01 Novartis Ag Organic compounds
ES2298049B1 (es) * 2006-07-21 2009-10-20 Laboratorios Almirall S.A. Procedimiento para fabricar bromuro de 3(r)-(2-hidroxi-2,2-ditien-2-ilacetoxi)-1-(3-fenoxipropil)-1-azoniabiciclo (2.2.2) octano.
EP2121688A1 (en) * 2007-02-15 2009-11-25 Argenta Discovery Ltd Heterocyclic derivatives as m3 muscarinic receptors
JP5656288B2 (ja) 2007-09-07 2015-01-21 セラヴァンス バイオファーマ アール＆ディー アイピー， エルエルシー ムスカリン受容体アンタゴニストとして有用なグアジニン含有化合物
CA2608561A1 (en) * 2007-10-29 2009-04-29 Carl Paluszkiewicz Motorcycle wind deflector accessory support
US8017617B2 (en) 2007-12-14 2011-09-13 Theravance, Inc. Amidine-containing compounds useful as muscarinic receptor antagonists
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100598A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
US20090326004A1 (en) 2008-06-03 2009-12-31 Ranbaxy Laboratories Limited Muscarinic receptor antagonists
ES2617680T3 (es) * 2009-04-09 2017-06-19 Novartis Ag Proceso para la preparación de sales de pirrolidinio
EP2510928A1 (en) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium for use in improving the quality of sleep in respiratory patients
WO2014086852A1 (en) * 2012-12-05 2014-06-12 Chiesi Farmaceutici S.P.A. Phenylethylpyridine derivatives as pde4-inhibitors
CN103755699A (zh) * 2014-01-06 2014-04-30 万特制药(海南)有限公司 一种2-羟基-2,2-二噻吩-2-基乙酸-1-氮杂二环[2,2,2]辛-3(r)-基酯制备方法
CN103755698A (zh) * 2014-01-06 2014-04-30 万特制药(海南)有限公司 一锅法制备阿地溴铵的工艺
KR101511090B1 (ko) 2014-04-24 2015-04-10 고려대학교 산학협력단 염증성 질환의 예방 또는 치료용 약학 조성물

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1219606A (en) * 1968-07-15 1971-01-20 Rech S Et D Applic Scient Soge Quinuclidinol derivatives and preparation thereof
US4843074A (en) * 1988-05-17 1989-06-27 Marion Laboratories, Inc. 1-azabicyclo[2.2.2]octan-3-yl 2-aryl-3-azacyclo-2-hydroxypropionates and their quaternary salts
NO2005012I1 (no) * 1994-12-28 2005-06-06 Debio Rech Pharma Sa Triptorelin og farmasoytisk akseptable salter derav
ES2165768B1 (es) * 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
DE60121813T2 (de) * 2000-12-28 2007-09-20 Almirall Ag Neue chinuclidinderivate und medizinische zusammensetzungen, die diese verbindungen enthalten
CN1571787A (zh) * 2001-10-17 2005-01-26 Ucb公司 奎宁环衍生物、制备它们的方法和它们作为m2和/或m3毒蕈碱受体抑制剂的用途
ES2204295B1 (es) * 2002-07-02 2005-08-01 Almirall Prodesfarma, S.A. Nuevos derivados de quinuclidina-amida.
AR044134A1 (es) * 2003-05-02 2005-08-24 Novartis Ag Derivados de quinuclidina, metodo de preparacion y composiciones farmaceuticas.

Also Published As

Publication number Publication date
BRPI0508177A (pt) 2007-08-07
ATE399166T1 (de) 2008-07-15
NZ548583A (en) 2010-05-28
ES2239546B1 (es) 2006-12-01
SI1725552T1 (sl) 2008-10-31
MY142036A (en) 2010-08-16
TW200604196A (en) 2006-02-01
DE602005007714D1 (de) 2008-08-07
JP2007529444A (ja) 2007-10-25
DK1725552T3 (da) 2008-10-13
UA88634C2 (en) 2009-11-10
IL177341A0 (en) 2006-12-10
HK1101855A1 (en) 2007-10-26
ES2307168T3 (es) 2008-11-16
EP1725552A1 (en) 2006-11-29
PL1725552T3 (pl) 2008-12-31
RU2006136085A (ru) 2008-04-27
ES2239546A1 (es) 2005-09-16
AU2005223310A1 (en) 2005-09-29
KR20070003940A (ko) 2007-01-05
ECSP066770A (es) 2006-11-16
RU2382041C2 (ru) 2010-02-20
US20080214600A1 (en) 2008-09-04
ZA200605931B (en) 2007-11-28
EP1725552B1 (en) 2008-06-25
WO2005090342A1 (en) 2005-09-29
HRP20080338T3 (hr) 2008-07-31
PE20060005A1 (es) 2006-01-28
AR048004A1 (es) 2006-03-15
PT1725552E (pt) 2008-09-18
CN1930158A (zh) 2007-03-14
CY1108324T1 (el) 2014-02-12
CA2560157A1 (en) 2005-09-29
RS50566B (sr) 2010-05-07

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