NO20091101L - Farmasoytisk formulering inneholdenede fenylamidin derivativ og anvendelsesmetode for farmasoytisk formulering i combinasjon med en antifungal agent - Google Patents

Farmasoytisk formulering inneholdenede fenylamidin derivativ og anvendelsesmetode for farmasoytisk formulering i combinasjon med en antifungal agent

Info

Publication number
NO20091101L
NO20091101L NO20091101A NO20091101A NO20091101L NO 20091101 L NO20091101 L NO 20091101L NO 20091101 A NO20091101 A NO 20091101A NO 20091101 A NO20091101 A NO 20091101A NO 20091101 L NO20091101 L NO 20091101L
Authority
NO
Norway
Prior art keywords
pharmaceutical formulation
combination
phenylamidine derivative
antifungal agents
antifungal agent
Prior art date
Application number
NO20091101A
Other languages
English (en)
Inventor
Hiroshi Nishikawa
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of NO20091101L publication Critical patent/NO20091101L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4465—Non condensed piperidines, e.g. piperocaine only substituted in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Et farmasøytisk preparat omfattende et fenylamidin derivat eller et salt derav, representert ved generell formel, hvor Rog Rkan være like eller forskjellig og representerer en eventuelt substituert C_alkylgruppe; og ett eller flere midler valgt fra azol antisoppmidler, polyen antisoppmidler, candin antisoppmidler og fluorpyrimidin antisoppmidler og en metode for kombinasjonsanvendelse av fenylamidin derivatet eller et salt derav og midlene er anvendelige for behandling av soppinfeksjoner forårsaket av et sopp-patogen.
NO20091101A 2006-10-06 2009-03-13 Farmasoytisk formulering inneholdenede fenylamidin derivativ og anvendelsesmetode for farmasoytisk formulering i combinasjon med en antifungal agent NO20091101L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006274709 2006-10-06
PCT/JP2007/069341 WO2008044562A1 (en) 2006-10-06 2007-10-03 Pharmaceutical composition comprising phenylamidine derivative and method of using the pharmaceutical composition in combination with antifungal agent

Publications (1)

Publication Number Publication Date
NO20091101L true NO20091101L (no) 2009-04-27

Family

ID=39282771

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20091101A NO20091101L (no) 2006-10-06 2009-03-13 Farmasoytisk formulering inneholdenede fenylamidin derivativ og anvendelsesmetode for farmasoytisk formulering i combinasjon med en antifungal agent

Country Status (21)

Country Link
US (1) US8173157B2 (no)
EP (1) EP2070536B1 (no)
JP (1) JP5132569B2 (no)
KR (1) KR101409258B1 (no)
CN (1) CN101522195B (no)
AT (1) ATE538789T1 (no)
AU (1) AU2007305626B2 (no)
BR (1) BRPI0719157A2 (no)
CA (1) CA2664915C (no)
CY (1) CY1112617T1 (no)
DK (1) DK2070536T3 (no)
ES (1) ES2376130T3 (no)
MX (1) MX2009003533A (no)
NO (1) NO20091101L (no)
NZ (1) NZ575714A (no)
PL (1) PL2070536T3 (no)
PT (1) PT2070536E (no)
RU (1) RU2429843C2 (no)
SI (1) SI2070536T1 (no)
WO (1) WO2008044562A1 (no)
ZA (1) ZA200902053B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI385169B (zh) 2005-10-31 2013-02-11 Eisai R&D Man Co Ltd 經雜環取代之吡啶衍生物及含有彼之抗真菌劑
TW200841879A (en) 2007-04-27 2008-11-01 Eisai R&D Man Co Ltd Pyridine derivatives substituted by heterocyclic ring and phosphonoamino group, and anti-fungal agent containing same
TWI395735B (zh) 2007-07-04 2013-05-11 Toyama Chemical Co Ltd ４－｛３－〔４－（３－｛４－〔胺基（丁氧基羰基亞胺基）甲基〕苯氧基｝丙基）－１－哌啶基〕丙氧基｝－ｎ’－（丁氧基羰基）苄脒之新穎結晶
WO2012060448A1 (ja) 2010-11-05 2012-05-10 エーザイ・アール・アンド・ディー・マネジメント株式会社 抗真菌剤としての併用医薬組成物
US9981040B2 (en) * 2012-04-20 2018-05-29 Eisai R&D Management Co., Ltd. Capsule formulation
ES2942285T3 (es) 2016-10-31 2023-05-31 Biocryst Pharm Inc Profármacos de inhibidores de la calicreína

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4782059A (en) * 1986-09-29 1988-11-01 Merck & Co., Inc. Method of controlling mycotic infections and compositions therefor
JPH03288051A (ja) 1990-03-30 1991-12-18 Mazda Motor Corp カムシャフトおよびその製造方法
GB9509631D0 (en) * 1995-05-12 1995-07-05 Sandoz Ltd Antifungal combination
ES2203819T3 (es) 1996-09-12 2004-04-16 MERCK & CO., INC. Terapia antifungica combinada.
AUPQ066399A0 (en) 1999-05-31 1999-06-24 Fujisawa Pharmaceutical Co., Ltd. Antifungal combination use
FR2829362B1 (fr) * 2001-09-10 2003-11-07 Aventis Cropscience Sa Composition fongicide a base de derives d'arylamidine et de composes fongicides connus
DK1481966T3 (da) * 2002-03-06 2011-10-24 Toyama Chemical Co Ltd Nyt arylamidinderivat eller salt deraf
JP2007504460A (ja) 2003-09-05 2007-03-01 メルク　エンド　カムパニー　インコーポレーテッド 固定相及び該固定相を用いた精製プロセス
JP4937506B2 (ja) * 2003-09-05 2012-05-23 富山化学工業株式会社 新規なアリールアミジン誘導体またはその塩
JP4885722B2 (ja) * 2004-06-30 2012-02-29 富山化学工業株式会社 新規なアリールアミジン誘導体およびその塩ならびにそれらを含有する抗真菌剤
CN1596897A (zh) 2004-07-26 2005-03-23 范敏华 一种伊曲康唑注射剂及其制备方法
WO2006011499A1 (ja) * 2004-07-28 2006-02-02 Toyama Chemical Co., Ltd. 新規なアリールアミジン誘導体およびその塩ならびにそれらを含有する抗真菌剤
SI1867332T1 (sl) * 2005-04-07 2011-11-30 Toyama Chemical Co Ltd Farmacevtska sestava in postopek z rabo v kombinaciji s protiglivičnim sredstvom
WO2007055197A1 (ja) 2005-11-09 2007-05-18 Toyama Chemical Co., Ltd. ４－（３－（４－（３－（４－シアノフェノキシ）プロピル）－１－ピペリジニル）プロポキシ）ベンゾニトリルの製造法およびその中間体
ZA200805604B (en) * 2005-12-29 2009-12-30 Toyama Chemical Co Ltd Novel arylamidine derivative, salt thereof and antifungal agent containing those

Also Published As

Publication number Publication date
EP2070536B1 (en) 2011-12-28
DK2070536T3 (da) 2012-04-10
JPWO2008044562A1 (ja) 2010-02-12
JP5132569B2 (ja) 2013-01-30
PL2070536T3 (pl) 2012-06-29
MX2009003533A (es) 2009-07-17
KR101409258B1 (ko) 2014-06-18
AU2007305626A1 (en) 2008-04-17
BRPI0719157A2 (pt) 2014-02-04
ATE538789T1 (de) 2012-01-15
US20100098750A1 (en) 2010-04-22
AU2007305626B2 (en) 2013-01-10
EP2070536A1 (en) 2009-06-17
NZ575714A (en) 2011-05-27
PT2070536E (pt) 2012-03-06
RU2429843C2 (ru) 2011-09-27
CA2664915A1 (en) 2008-04-17
RU2009117207A (ru) 2010-11-20
SI2070536T1 (sl) 2012-03-30
EP2070536A4 (en) 2010-02-10
CN101522195B (zh) 2012-01-18
CA2664915C (en) 2014-01-07
CY1112617T1 (el) 2016-02-10
WO2008044562A1 (en) 2008-04-17
ZA200902053B (en) 2010-07-28
ES2376130T3 (es) 2012-03-09
CN101522195A (zh) 2009-09-02
KR20090069317A (ko) 2009-06-30
US8173157B2 (en) 2012-05-08

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