DK2070536T3 - Farmaceutisk sammensætning med et phenylamidin-derivat og fremgangsmåde til anvendelse af den farmaceutiske sammensætning i kombination med et antifungalt middel - Google Patents

Farmaceutisk sammensætning med et phenylamidin-derivat og fremgangsmåde til anvendelse af den farmaceutiske sammensætning i kombination med et antifungalt middel

Info

Publication number: DK2070536T3
Authority: DK; Denmark
Prior art keywords: pharmaceutical composition; antifungal agents; combination; phenylamidine derivative; agents
Prior art date: 2006-10-06

Application number

DK07829080.6T

Other languages

English (en)

Inventor

Hiroshi Nishikawa

Original Assignee

Toyama Chemical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-10-06

Filing date

2007-10-03

Publication date

2012-04-10

2007-10-03 Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd

2012-04-10 Application granted granted Critical

2012-04-10 Publication of DK2070536T3 publication Critical patent/DK2070536T3/da

Links

229940121375 antifungal agent Drugs 0.000 title abstract 5
239000003429 antifungal agent Substances 0.000 title abstract 5
PXXJHWLDUBFPOL-UHFFFAOYSA-N benzamidine Chemical class NC(=N)C1=CC=CC=C1 PXXJHWLDUBFPOL-UHFFFAOYSA-N 0.000 title abstract 3
239000008194 pharmaceutical composition Substances 0.000 title abstract 3
KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical compound C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 abstract 2
239000003795 chemical substances by application Substances 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
WAVYAFBQOXCGSZ-UHFFFAOYSA-N 2-fluoropyrimidine Chemical compound FC1=NC=CC=N1 WAVYAFBQOXCGSZ-UHFFFAOYSA-N 0.000 abstract 1
206010017533 Fungal infection Diseases 0.000 abstract 1
208000031888 Mycoses Diseases 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
244000053095 fungal pathogen Species 0.000 abstract 1
150000004291 polyenes Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4465—Non condensed piperidines, e.g. piperocaine only substituted in position 4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Hydrogenated Pyridines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK07829080.6T 2006-10-06 2007-10-03 Farmaceutisk sammensætning med et phenylamidin-derivat og fremgangsmåde til anvendelse af den farmaceutiske sammensætning i kombination med et antifungalt middel DK2070536T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2006274709		2006-10-06
PCT/JP2007/069341 WO2008044562A1 (en)	2006-10-06	2007-10-03	Pharmaceutical composition comprising phenylamidine derivative and method of using the pharmaceutical composition in combination with antifungal agent

Publications (1)

Publication Number	Publication Date
DK2070536T3 true DK2070536T3 (da)	2012-04-10

Family

ID=39282771

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK07829080.6T DK2070536T3 (da)	2006-10-06	2007-10-03	Farmaceutisk sammensætning med et phenylamidin-derivat og fremgangsmåde til anvendelse af den farmaceutiske sammensætning i kombination med et antifungalt middel

Country Status (21)

Country	Link
US (1)	US8173157B2 (da)
EP (1)	EP2070536B1 (da)
JP (1)	JP5132569B2 (da)
KR (1)	KR101409258B1 (da)
CN (1)	CN101522195B (da)
AT (1)	ATE538789T1 (da)
AU (1)	AU2007305626B2 (da)
BR (1)	BRPI0719157A2 (da)
CA (1)	CA2664915C (da)
CY (1)	CY1112617T1 (da)
DK (1)	DK2070536T3 (da)
ES (1)	ES2376130T3 (da)
MX (1)	MX2009003533A (da)
NO (1)	NO20091101L (da)
NZ (1)	NZ575714A (da)
PL (1)	PL2070536T3 (da)
PT (1)	PT2070536E (da)
RU (1)	RU2429843C2 (da)
SI (1)	SI2070536T1 (da)
WO (1)	WO2008044562A1 (da)
ZA (1)	ZA200902053B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TWI385169B (zh)	2005-10-31	2013-02-11	Eisai R&D Man Co Ltd	經雜環取代之吡啶衍生物及含有彼之抗真菌劑
TW200841879A (en)	2007-04-27	2008-11-01	Eisai R&D Man Co Ltd	Pyridine derivatives substituted by heterocyclic ring and phosphonoamino group, and anti-fungal agent containing same
TWI395735B (zh)	2007-07-04	2013-05-11	Toyama Chemical Co Ltd	４－｛３－〔４－（３－｛４－〔胺基（丁氧基羰基亞胺基）甲基〕苯氧基｝丙基）－１－哌啶基〕丙氧基｝－ｎ’－（丁氧基羰基）苄脒之新穎結晶
US20130288956A1 (en)	2010-11-05	2013-10-31	Eisai R&D Management Co., Ltd.	Combined pharmaceutical composition as antifungal agent
TWI574705B (zh) *	2012-04-20	2017-03-21	衛材Ｒ＆Ｄ企管股份有限公司	Capsules
MA46642A (fr)	2016-10-31	2021-04-21	Biocryst Pharm Inc	Promédicaments d'inhibiteurs de la kallicréine

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4782059A (en) *	1986-09-29	1988-11-01	Merck & Co., Inc.	Method of controlling mycotic infections and compositions therefor
JPH03288051A (ja)	1990-03-30	1991-12-18	Mazda Motor Corp	カムシャフトおよびその製造方法
GB9509631D0 (en) *	1995-05-12	1995-07-05	Sandoz Ltd	Antifungal combination
CZ88499A3 (cs)	1996-09-12	1999-10-13	Merck And Co., Inc.	Kombinace látek s antifungálním účinkem
AUPQ066399A0 (en)	1999-05-31	1999-06-24	Fujisawa Pharmaceutical Co., Ltd.	Antifungal combination use
FR2829362B1 (fr) *	2001-09-10	2003-11-07	Aventis Cropscience Sa	Composition fongicide a base de derives d'arylamidine et de composes fongicides connus
NZ534962A (en)	2002-03-06	2005-07-29	Toyama Chemical Co Ltd	Novel arylamidine derivative or salt thereof
JP4937506B2 (ja)	2003-09-05	2012-05-23	富山化学工業株式会社	新規なアリールアミジン誘導体またはその塩
JP2007504460A (ja)	2003-09-05	2007-03-01	メルク　エンド　カムパニー　インコーポレーテッド	固定相及び該固定相を用いた精製プロセス
EP1767526B1 (en) *	2004-06-30	2012-10-24	Toyama Chemical Co., Ltd.	Arylamidine derivative, salt thereof and antifungal containing these
CN1596897A (zh)	2004-07-26	2005-03-23	范敏华	一种伊曲康唑注射剂及其制备方法
WO2006011499A1 (ja)	2004-07-28	2006-02-02	Toyama Chemical Co., Ltd.	新規なアリールアミジン誘導体およびその塩ならびにそれらを含有する抗真菌剤
BRPI0607910A2 (pt) *	2005-04-07	2010-03-23	Toyama Chemical Co Ltd	composiÇço farmacÊutica para tratar infecÇÕes féngicas, e, mÉtodo de uso de um derivado de arilamidina ou um sal do mesmo
JP5314284B2 (ja)	2005-11-09	2013-10-16	富山化学工業株式会社	４−（３−（４−（３−（４−シアノフェノキシ）プロピル）−１−ピペリジニル）プロポキシ）ベンゾニトリルの製造法およびその中間体
CN101351204B (zh)	2005-12-29	2011-01-12	富山化学工业株式会社	芳脒衍生物及其盐、以及含有它们的抗真菌药

2007
- 2007-10-03 MX MX2009003533A patent/MX2009003533A/es active IP Right Grant
- 2007-10-03 JP JP2008538673A patent/JP5132569B2/ja not_active Expired - Fee Related
- 2007-10-03 SI SI200730827T patent/SI2070536T1/sl unknown
- 2007-10-03 WO PCT/JP2007/069341 patent/WO2008044562A1/ja not_active Ceased
- 2007-10-03 DK DK07829080.6T patent/DK2070536T3/da active
- 2007-10-03 BR BRPI0719157-0A patent/BRPI0719157A2/pt not_active IP Right Cessation
- 2007-10-03 CA CA2664915A patent/CA2664915C/en not_active Expired - Fee Related
- 2007-10-03 AU AU2007305626A patent/AU2007305626B2/en not_active Ceased
- 2007-10-03 RU RU2009117207/15A patent/RU2429843C2/ru not_active IP Right Cessation
- 2007-10-03 ES ES07829080T patent/ES2376130T3/es active Active
- 2007-10-03 KR KR1020097008232A patent/KR101409258B1/ko not_active Expired - Fee Related
- 2007-10-03 AT AT07829080T patent/ATE538789T1/de active
- 2007-10-03 EP EP07829080A patent/EP2070536B1/en not_active Not-in-force
- 2007-10-03 CN CN2007800371777A patent/CN101522195B/zh not_active Expired - Fee Related
- 2007-10-03 PL PL07829080T patent/PL2070536T3/pl unknown
- 2007-10-03 US US12/443,750 patent/US8173157B2/en not_active Expired - Fee Related
- 2007-10-03 ZA ZA200902053A patent/ZA200902053B/xx unknown
- 2007-10-03 PT PT07829080T patent/PT2070536E/pt unknown
- 2007-10-03 NZ NZ575714A patent/NZ575714A/en not_active IP Right Cessation
2009
- 2009-03-13 NO NO20091101A patent/NO20091101L/no not_active Application Discontinuation
2012
- 2012-01-17 CY CY20121100053T patent/CY1112617T1/el unknown

Also Published As

Publication number	Publication date
NO20091101L (no)	2009-04-27
US8173157B2 (en)	2012-05-08
CN101522195A (zh)	2009-09-02
EP2070536B1 (en)	2011-12-28
CY1112617T1 (el)	2016-02-10
JP5132569B2 (ja)	2013-01-30
AU2007305626B2 (en)	2013-01-10
CA2664915A1 (en)	2008-04-17
US20100098750A1 (en)	2010-04-22
BRPI0719157A2 (pt)	2014-02-04
SI2070536T1 (sl)	2012-03-30
RU2009117207A (ru)	2010-11-20
JPWO2008044562A1 (ja)	2010-02-12
RU2429843C2 (ru)	2011-09-27
MX2009003533A (es)	2009-07-17
KR20090069317A (ko)	2009-06-30
ZA200902053B (en)	2010-07-28
CN101522195B (zh)	2012-01-18
KR101409258B1 (ko)	2014-06-18
ES2376130T3 (es)	2012-03-09
AU2007305626A1 (en)	2008-04-17
EP2070536A4 (en)	2010-02-10
EP2070536A1 (en)	2009-06-17
CA2664915C (en)	2014-01-07
NZ575714A (en)	2011-05-27
WO2008044562A1 (en)	2008-04-17
ATE538789T1 (de)	2012-01-15
PL2070536T3 (pl)	2012-06-29
PT2070536E (pt)	2012-03-06

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