NO20091480L - Aminometyl-2-imidazoler med affinitet mot sporamin-assosierte reseptorer - Google Patents

Aminometyl-2-imidazoler med affinitet mot sporamin-assosierte reseptorer

Info

Publication number: NO20091480L
Authority: NO; Norway
Prior art keywords: disorders; compounds; disease; formula; associated receptors
Prior art date: 2006-10-19

Application number

NO20091480A

Other languages

English (en)

Norwegian (no)

Inventor

Guido Galley

Katrin Groebke Zbinden

Roger Norcross

Henri Stalder

Annick Goergler

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-10-19

Filing date

2009-04-17

Publication date

2009-04-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38819769&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20091480(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2009-04-17 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2009-04-30 Publication of NO20091480L publication Critical patent/NO20091480L/no

Links

208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 4
208000035475 disorder Diseases 0.000 abstract 4
150000001875 compounds Chemical class 0.000 abstract 3
102000011829 Trace amine associated receptor Human genes 0.000 abstract 2
108050002178 Trace amine associated receptor Proteins 0.000 abstract 2
208000024827 Alzheimer disease Diseases 0.000 abstract 1
208000019901 Anxiety disease Diseases 0.000 abstract 1
208000006096 Attention Deficit Disorder with Hyperactivity Diseases 0.000 abstract 1
208000020925 Bipolar disease Diseases 0.000 abstract 1
208000024172 Cardiovascular disease Diseases 0.000 abstract 1
208000002249 Diabetes Complications Diseases 0.000 abstract 1
206010012655 Diabetic complications Diseases 0.000 abstract 1
208000032928 Dyslipidaemia Diseases 0.000 abstract 1
208000030814 Eating disease Diseases 0.000 abstract 1
208000019454 Feeding and Eating disease Diseases 0.000 abstract 1
101000890887 Homo sapiens Trace amine-associated receptor 1 Proteins 0.000 abstract 1
208000017170 Lipid metabolism disease Diseases 0.000 abstract 1
208000019695 Migraine disease Diseases 0.000 abstract 1
208000012902 Nervous system disease Diseases 0.000 abstract 1
208000025966 Neurological disease Diseases 0.000 abstract 1
208000008589 Obesity Diseases 0.000 abstract 1
208000018737 Parkinson disease Diseases 0.000 abstract 1
208000028017 Psychotic disease Diseases 0.000 abstract 1
102100040114 Trace amine-associated receptor 1 Human genes 0.000 abstract 1
230000006978 adaptation Effects 0.000 abstract 1
230000036760 body temperature Effects 0.000 abstract 1
206010012601 diabetes mellitus Diseases 0.000 abstract 1
235000014632 disordered eating Nutrition 0.000 abstract 1
238000005265 energy consumption Methods 0.000 abstract 1
206010015037 epilepsy Diseases 0.000 abstract 1
230000013632 homeostatic process Effects 0.000 abstract 1
208000030159 metabolic disease Diseases 0.000 abstract 1
208000015122 neurodegenerative disease Diseases 0.000 abstract 1
235000020824 obesity Nutrition 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
201000000980 schizophrenia Diseases 0.000 abstract 1
208000019116 sleep disease Diseases 0.000 abstract 1
201000009032 substance abuse Diseases 0.000 abstract 1
231100000736 substance abuse Toxicity 0.000 abstract 1
208000011117 substance-related disease Diseases 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/417—Imidazole-alkylamines, e.g. histamine, phentolamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A61P25/10—Antiepileptics; Anticonvulsants for petit-mal
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Diabetes (AREA)
Pain & Pain Management (AREA)
Hematology (AREA)
Obesity (AREA)
Psychiatry (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Child & Adolescent Psychology (AREA)
Addiction (AREA)
Urology & Nephrology (AREA)
Psychology (AREA)
Vascular Medicine (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

NO20091480A 2006-10-19 2009-04-17 Aminometyl-2-imidazoler med affinitet mot sporamin-assosierte reseptorer NO20091480L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP06122553		2006-10-19
PCT/EP2007/060664 WO2008046756A1 (en)	2006-10-19	2007-10-09	Aminomethyl-2-imidazoles with affinity with the trace amine associated receptors

Publications (1)

Publication Number	Publication Date
NO20091480L true NO20091480L (no)	2009-04-30

Family

ID=38819769

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20091480A NO20091480L (no)	2006-10-19	2009-04-17	Aminometyl-2-imidazoler med affinitet mot sporamin-assosierte reseptorer

Country Status (21)

Country	Link
US (1)	US20080096906A1 (de)
EP (1)	EP2076496B1 (de)
JP (1)	JP5167265B2 (de)
KR (1)	KR101172940B1 (de)
CN (1)	CN101528709B (de)
AR (1)	AR063326A1 (de)
AT (1)	ATE462696T1 (de)
AU (1)	AU2007312389B2 (de)
BR (1)	BRPI0718059A2 (de)
CA (1)	CA2665255A1 (de)
CL (1)	CL2007002970A1 (de)
DE (1)	DE602007005671D1 (de)
ES (1)	ES2340223T3 (de)
IL (1)	IL197872A (de)
MX (1)	MX2009003887A (de)
NO (1)	NO20091480L (de)
PE (1)	PE20080984A1 (de)
RU (1)	RU2009112495A (de)
TW (1)	TW200835494A (de)
WO (1)	WO2008046756A1 (de)
ZA (1)	ZA200902279B (de)

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EP1976828B1 (de)	2005-12-29	2016-12-21	Celtaxsys, Inc.	Diaminderivate als inhibitoren von leukotrien-a4-hydrolase
RU2439062C2 (ru) *	2006-10-19	2012-01-10	Ф.Хоффманн-Ля Рош Аг	Производные имидазолона и имидазолидинона как 11в-hsd1 ингибиторы при диабете
AU2007312390B2 (en)	2006-10-19	2013-03-28	F. Hoffmann-La Roche Ag	Aminomethyl-4-imidazoles
CN101765587A (zh) *	2007-07-27	2010-06-30	弗·哈夫曼-拉罗切有限公司	作为taar配体的2-氮杂环丁烷甲胺类和2-吡咯烷甲胺类
US8242153B2 (en) *	2008-07-24	2012-08-14	Hoffmann-La Roche Inc.	4,5-dihydro-oxazol-2YL derivatives
ES2864862T3 (es)	2013-03-12	2021-10-14	Celltaxis Llc	Métodos de inhibición de la leucotrieno A4 hidrolasa
MX2015011678A (es)	2013-03-14	2016-07-08	Celtaxsys Inc	Inhibidores de leucotrieno a4 hidrolasa.
CA2906086A1 (en)	2013-03-14	2014-09-25	Celtaxsys, Inc.	Inhibitors of leukotriene a4 hydrolase
MX2015011677A (es) *	2013-03-14	2016-07-08	Celtaxsys Inc	Inhibidores de leucotrieno a4 hidrolasa.
US10898484B2 (en)	2018-05-31	2021-01-26	Celltaxis, Llc	Method of reducing pulmonary exacerbations in respiratory disease patients
CN115073273B (zh) *	2021-03-15	2024-09-17	中国医学科学院药物研究所	二苯烷类化合物及其制备方法、药物组合物和用途
TWI836390B (zh) *	2021-03-29	2024-03-21	大陸商上海樞境生物科技有限公司	含螺環類衍生物、其製備方法和應用

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KR100492252B1 (ko) *	2002-08-09	2005-05-30	한국화학연구원	이미다졸을 포함하는 이차아민으로 치환된 벤조피란유도체 및 그의 제조방법
JP2008540441A (ja) *	2005-05-03	2008-11-20	バイエル・クロツプサイエンス・アクチエンゲゼルシヤフト	殺虫性の置換されたアミノアルキル複素環式及びヘテロアリール誘導体

2007
- 2007-10-09 DE DE602007005671T patent/DE602007005671D1/de active Active
- 2007-10-09 EP EP07821037A patent/EP2076496B1/de not_active Not-in-force
- 2007-10-09 KR KR1020097007959A patent/KR101172940B1/ko not_active Expired - Fee Related
- 2007-10-09 MX MX2009003887A patent/MX2009003887A/es active IP Right Grant
- 2007-10-09 CN CN2007800387578A patent/CN101528709B/zh not_active Expired - Fee Related
- 2007-10-09 WO PCT/EP2007/060664 patent/WO2008046756A1/en not_active Ceased
- 2007-10-09 JP JP2009532766A patent/JP5167265B2/ja not_active Expired - Fee Related
- 2007-10-09 ES ES07821037T patent/ES2340223T3/es active Active
- 2007-10-09 RU RU2009112495/04A patent/RU2009112495A/ru not_active Application Discontinuation
- 2007-10-09 AU AU2007312389A patent/AU2007312389B2/en not_active Ceased
- 2007-10-09 BR BRPI0718059-4A patent/BRPI0718059A2/pt not_active IP Right Cessation
- 2007-10-09 CA CA002665255A patent/CA2665255A1/en not_active Abandoned
- 2007-10-09 AT AT07821037T patent/ATE462696T1/de active
- 2007-10-15 US US11/872,192 patent/US20080096906A1/en not_active Abandoned
- 2007-10-17 CL CL200702970A patent/CL2007002970A1/es unknown
- 2007-10-17 PE PE2007001406A patent/PE20080984A1/es not_active Application Discontinuation
- 2007-10-17 AR ARP070104589A patent/AR063326A1/es not_active Application Discontinuation
- 2007-10-17 TW TW096138927A patent/TW200835494A/zh unknown
2009
- 2009-03-26 IL IL197872A patent/IL197872A/en not_active IP Right Cessation
- 2009-04-01 ZA ZA200902279A patent/ZA200902279B/xx unknown
- 2009-04-17 NO NO20091480A patent/NO20091480L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
ES2340223T3 (es)	2010-05-31
EP2076496B1 (de)	2010-03-31
US20080096906A1 (en)	2008-04-24
BRPI0718059A2 (pt)	2013-11-05
CN101528709A (zh)	2009-09-09
CN101528709B (zh)	2012-02-01
AR063326A1 (es)	2009-01-21
AU2007312389A1 (en)	2008-04-24
DE602007005671D1 (de)	2010-05-12
KR101172940B1 (ko)	2012-08-10
ZA200902279B (en)	2010-03-31
CA2665255A1 (en)	2008-04-24
ATE462696T1 (de)	2010-04-15
KR20090055640A (ko)	2009-06-02
RU2009112495A (ru)	2010-11-27
PE20080984A1 (es)	2008-07-19
JP5167265B2 (ja)	2013-03-21
AU2007312389B2 (en)	2012-02-23
CL2007002970A1 (es)	2008-05-30
EP2076496A1 (de)	2009-07-08
JP2010506874A (ja)	2010-03-04
TW200835494A (en)	2008-09-01
WO2008046756A1 (en)	2008-04-24
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Publication	Publication Date	Title
MX2009003887A (es)	2009-04-22	Aminometil-2-imidazoles con afinidad con los receptores asociados a trazas de amina.
TW200833685A (en)	2008-08-16	Aminomethyl-4-imidazoles
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PH12013502315A1 (en)	2016-05-11	Pyrazole derivatives
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CO6331336A2 (es)	2011-10-20	Derivados de 4,5-dihidro-oxazol-2-ilo
BR112017000160A2 (pt)	2017-10-31	derivados de azetidina substituidos como ligantes de taar
MX2009005920A (es)	2009-06-16	Nuevos 2-imidazoles como ligandos para receptores asociados con trazas de amina.
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PH12015500489A1 (en)	2015-04-20	Pyrazole carboxamide derivatives as taar modulators for use in the treatment of several disorders, such as depression, diabetes and parkinsons disease
MX2009013745A (es)	2010-01-26	4-imidazolinas y su uso como antidepresivos.
WO2007090720A3 (en)	2007-09-20	Use of 2-imidazoles for the treatment of cns disorders
MX2016012624A (es)	2016-12-14	Derivados de 5-oxa-2-azabiciclo[2.2.2]octan-4-ilo y 5-oxa-2-azabiciclo[2.2.1]heptan-4-ilo como modularores de los receptores asociados a la amina de trazas 1 (taar1).
MX2009004617A (es)	2009-05-22	2-imidazoles sustituidos como moduladores de los receptores asociados con trazas de amina.
MX349738B (es)	2017-08-10	Derivados de dihidrooxazol-2-amina.
NO20091721L (no)	2009-07-28	Substituerte 4-imidazoler
NZ744194B2 (en)	2025-01-07	5-ethyl-4-methyl-pyrazole-3-carboxamide derivative having activity as agonist of taar