NO2513070T3 - - Google Patents
Info
- Publication number
- NO2513070T3 NO2513070T3 NO10796247A NO10796247A NO2513070T3 NO 2513070 T3 NO2513070 T3 NO 2513070T3 NO 10796247 A NO10796247 A NO 10796247A NO 10796247 A NO10796247 A NO 10796247A NO 2513070 T3 NO2513070 T3 NO 2513070T3
- Authority
- NO
- Norway
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28676509P | 2009-12-15 | 2009-12-15 | |
| PCT/US2010/060439 WO2011084453A1 (fr) | 2009-12-15 | 2010-12-15 | Sels de thiazolidinedione épargnant les ppar pour le traitement des maladies métaboliques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO2513070T3 true NO2513070T3 (fr) | 2018-04-07 |
Family
ID=43501294
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO10796247A NO2513070T3 (fr) | 2009-12-15 | 2010-12-15 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US8912335B2 (fr) |
| EP (1) | EP2513070B1 (fr) |
| JP (1) | JP5634526B2 (fr) |
| KR (3) | KR20120107493A (fr) |
| CN (1) | CN102753539B (fr) |
| AU (1) | AU2010340055B2 (fr) |
| CA (1) | CA2783468C (fr) |
| DK (1) | DK2513070T3 (fr) |
| ES (1) | ES2658168T3 (fr) |
| HU (1) | HUE038042T2 (fr) |
| MX (1) | MX2012006725A (fr) |
| NO (1) | NO2513070T3 (fr) |
| NZ (1) | NZ600390A (fr) |
| PL (1) | PL2513070T3 (fr) |
| RU (1) | RU2564661C2 (fr) |
| WO (1) | WO2011084453A1 (fr) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2564661C2 (ru) | 2009-12-15 | 2015-10-10 | МЕТАБОЛИК СОЛЮШНЗ ДЕВЕЛОПМЕНТ КОМПАНИ, ЭлЭлСи | Соли тиазолидиндиона со сниженным сродством к ppar для лечения нарушений обмена веществ |
| UA116217C2 (uk) | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
| HK1211232A1 (en) | 2012-12-21 | 2016-05-20 | Sanofi | Exendin-4 derivatives as dual glp1/gip or trigonal glp1/gip/glucagon agonists |
| WO2015013187A1 (fr) | 2013-07-22 | 2015-01-29 | Metabolic Solutions Development Co., Llc | Composés épargnant les ppar pour le traitement de maladies métaboliques |
| EP3080152A1 (fr) | 2013-12-13 | 2016-10-19 | Sanofi | Analogues peptidiques de l'exendine 4 non acylés |
| WO2015086728A1 (fr) | 2013-12-13 | 2015-06-18 | Sanofi | Analogues peptidiques de l'exendine 4 en tant qu'agonistes mixtes des récepteurs glp-1/gip |
| WO2015086733A1 (fr) | 2013-12-13 | 2015-06-18 | Sanofi | Agonistes mixtes des récepteurs du glp-1/glucagon |
| TW201609799A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 雙重glp-1/gip受體促效劑 |
| TW201625670A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自exendin-4之雙重glp-1/升糖素受體促效劑 |
| TW201625668A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 作為胜肽性雙重glp-1/昇糖素受體激動劑之艾塞那肽-4衍生物 |
| TW201625669A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自艾塞那肽-4(Exendin-4)之肽類雙重GLP-1/升糖素受體促效劑 |
| US9932381B2 (en) | 2014-06-18 | 2018-04-03 | Sanofi | Exendin-4 derivatives as selective glucagon receptor agonists |
| AR105319A1 (es) | 2015-06-05 | 2017-09-27 | Sanofi Sa | Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico |
| AR105284A1 (es) | 2015-07-10 | 2017-09-20 | Sanofi Sa | Derivados de exendina-4 como agonistas peptídicos duales específicos de los receptores de glp-1 / glucagón |
| WO2019154958A1 (fr) | 2018-02-08 | 2019-08-15 | Enyo Pharma | Utilisation de modulateurs de protéines neet pour le traitement d'une infection |
| CN111689934B (zh) * | 2020-06-24 | 2022-08-02 | 郑州大学 | 14-脱羟-13-脱氢穿心莲内酯-12-磺酸钾的单晶体及制备方法 |
| GB202210503D0 (en) | 2022-07-18 | 2022-08-31 | Univ Court Univ Of Glasgow | Materials and methods for treatment of chronic myeloid leukemia (CML) |
Family Cites Families (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5522636A (en) | 1978-08-04 | 1980-02-18 | Takeda Chem Ind Ltd | Thiazoliding derivative |
| WO1985004170A1 (fr) | 1984-03-21 | 1985-09-26 | Takeda Chemical Industries, Ltd. | Derives de thiazolidinedione, leur procede de preparation et compositions medicinales les contenant |
| US4582839A (en) | 1984-03-21 | 1986-04-15 | Takeda Chemical Industries, Ltd. | 2,4-thiazolidinediones |
| CN1003445B (zh) | 1984-10-03 | 1989-03-01 | 武田药品工业株式会社 | 噻唑烷二酮衍生物,其制备方法和用途 |
| WO1986002073A1 (fr) | 1984-10-03 | 1986-04-10 | Takeda Chemical Industries, Ltd. | Derives de thiazolidinedione, procede de preparation et composition pharmaceutique les contenant |
| AR240698A1 (es) | 1985-01-19 | 1990-09-28 | Takeda Chemical Industries Ltd | Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales |
| US5167228A (en) | 1987-06-26 | 1992-12-01 | Brigham And Women's Hospital | Assessment and modification of endogenous circadian phase and amplitude |
| US5304121A (en) | 1990-12-28 | 1994-04-19 | Boston Scientific Corporation | Drug delivery system making use of a hydrogel polymer coating |
| US5143930A (en) | 1990-02-07 | 1992-09-01 | Sankyo Company, Limited | Thiazolidine derivatives with anti-diabetic activity, their preparation and their use |
| US5356913A (en) | 1990-02-09 | 1994-10-18 | The Upjohn Company | Use of insulin sensitizing agents to treat hypertension |
| CA2106967C (fr) * | 1991-04-11 | 2003-12-09 | Takashi Sohda | Derives thiazolidinedione, leur production et leur utilisation |
| US5441971A (en) | 1991-04-11 | 1995-08-15 | The Upjohn Company | Thiazolidinedione derivatives, production and use thereof |
| NO302471B1 (no) | 1991-12-26 | 1998-03-09 | Sankyo Co | Tiazolidinforbindelser og farmasöytisk preparat |
| US5886026A (en) | 1993-07-19 | 1999-03-23 | Angiotech Pharmaceuticals Inc. | Anti-angiogenic compositions and methods of use |
| US6099562A (en) | 1996-06-13 | 2000-08-08 | Schneider (Usa) Inc. | Drug coating with topcoat |
| TWI238064B (en) * | 1995-06-20 | 2005-08-21 | Takeda Chemical Industries Ltd | A pharmaceutical composition for prophylaxis and treatment of diabetes |
| US5798375A (en) | 1995-07-03 | 1998-08-25 | Sankyo Company, Limited | Treatment of arteriosclerosis and xanthoma |
| US7407978B2 (en) | 1999-04-06 | 2008-08-05 | Theracos, Inc. | Heterocyclic analogs of diphenylethylene compounds |
| WO2000066102A2 (fr) | 1999-04-29 | 2000-11-09 | City Of Hope | Pentoxifylline, pioglitazone et metformine comme inhibiteurs de formation de produits terminaux de glycation avancee (age) |
| US6331596B1 (en) | 1999-06-28 | 2001-12-18 | Basf Corporation | Method of preparing carbamate-functional polymers |
| IL147308A0 (en) | 1999-06-30 | 2002-08-14 | Tularik Inc | Compounds for the modulation of pparγ activity and pharmaceutical compositions containing the same |
| WO2001082916A2 (fr) | 2000-05-03 | 2001-11-08 | Tularik Inc. | Compositions therapeutiques combinees et leurs methodes d'utilisation |
| US20040087484A1 (en) | 2000-12-01 | 2004-05-06 | Sahota Pritam Singh | Combination of organic compounds |
| US7009057B2 (en) | 2001-04-26 | 2006-03-07 | Zentiva A.S. | Method for obtaining pioglitazone as an antidiabetic agent |
| AU2002337749A1 (en) | 2001-09-28 | 2003-04-07 | Teva Pharmaceutical Industries Ltd. | Pioglitazone hydrochloride |
| AUPS236902A0 (en) | 2002-05-16 | 2002-06-13 | Northern Sydney Area Health Service | Composition and method for treating hypertension |
| DE60316152D1 (de) | 2002-07-16 | 2007-10-18 | Cadila Healthcare Ltd | Prozess zur herstellung von pioglitazon via verschiedene zwischenstufen |
| US20060083784A1 (en) | 2002-08-07 | 2006-04-20 | Smithkline Beecham Corporation | Amorphous pharmaceutical compositions |
| US7230016B2 (en) | 2003-05-13 | 2007-06-12 | Synthon Ip Inc. | Pioglitazone salts, such as pioglitazone sulfate, and pharmaceutical compositions and processes using the same |
| US20070078170A1 (en) | 2003-08-28 | 2007-04-05 | Khanduri Chandra H | Process for the preparation of pioglitazone |
| AR047541A1 (es) | 2004-02-13 | 2006-01-25 | Sandoz Ag | Fosfato de 5-[[4-[2-metil-2-piridinil-amino-etoxi]fenil]metil]-2,4 tiazolidinadiona (rosiglitazona) y sus formas polimorficas |
| JP4475983B2 (ja) | 2004-03-03 | 2010-06-09 | 学校法人日本大学 | Bmal1を阻害する方法 |
| KR100840465B1 (ko) | 2004-09-28 | 2008-06-20 | 오츠카 세이야쿠 가부시키가이샤 | 카르보스티릴 화합물 |
| UA96441C2 (ru) | 2006-03-16 | 2011-11-10 | Метаболик Солюшнз Девелопмент Компани | Фармацевтическая композиция, которая содержит аналог тиазолидиндиона митоглитазон, для лечения заболеваний, опосредованных метаболическим воспалением |
| CN101448500A (zh) | 2006-03-16 | 2009-06-03 | 新陈代谢解决方案开发公司 | 噻唑烷二酮类似物和糖皮质激素激动剂的组合疗法 |
| WO2007109037A2 (fr) | 2006-03-16 | 2007-09-27 | Metabolic Solutions Development Company | Analogues de thiazolidinedione |
| US8304441B2 (en) | 2007-09-14 | 2012-11-06 | Metabolic Solutions Development Company, Llc | Thiazolidinedione analogues for the treatment of metabolic diseases |
| KR101537830B1 (ko) * | 2007-09-14 | 2015-07-17 | 메타볼릭 솔루션스 디벨롭먼트 컴퍼니, 엘엘씨 | 고혈압 치료용 티아졸리딘디온 유사체 |
| US8722710B2 (en) | 2007-09-26 | 2014-05-13 | Deuterx, Llc | Deuterium-enriched pioglitazone |
| ES2399179T3 (es) * | 2008-08-07 | 2013-03-26 | Pulmagen Therapeutics (Inflammation) Limited | Tratamiento de enfermedad respiratoria |
| WO2010105048A1 (fr) | 2009-03-12 | 2010-09-16 | Metabolic Solutions Development Company | Analogues de thiazolidinedione |
| WO2011017244A1 (fr) | 2009-08-05 | 2011-02-10 | Metabolic Solutions Development Company | Polymorphes de 5-(4-(2-(5-éthylpyridin-2-yl)-2-oxoéthoxy)benzyl)-l,3-thiazolidine-2,4-dione (mitoglitazone) |
| WO2011084459A1 (fr) | 2009-12-15 | 2011-07-14 | Metabolic Solutions Development Company | Thiazolidine diones épargnant les ppar et associations pour le traitement de l'obésité et d'autres maladies métaboliques |
| ES2617704T3 (es) | 2009-12-15 | 2017-06-19 | Octeta Therapeutics, Llc | Tiazolidindionas ahorradoras de PPAR y combinaciones para el tratamiento de enfermedades neurodegenerativas |
| JP2013514369A (ja) | 2009-12-15 | 2013-04-25 | メタボリック ソリューションズ ディベロップメント カンパニー, エルエルシー | 糖尿病および他の代謝性疾患を処置するための、ppar温存チアゾリジンジオンおよび組み合わせ物 |
| RU2564661C2 (ru) | 2009-12-15 | 2015-10-10 | МЕТАБОЛИК СОЛЮШНЗ ДЕВЕЛОПМЕНТ КОМПАНИ, ЭлЭлСи | Соли тиазолидиндиона со сниженным сродством к ppar для лечения нарушений обмена веществ |
| AU2011242844A1 (en) | 2010-04-21 | 2012-11-01 | Metabolic Solutions Development Company, Llc | Thiazolidinedione analogues |
-
2010
- 2010-12-15 RU RU2012129930/04A patent/RU2564661C2/ru active
- 2010-12-15 ES ES10796247.4T patent/ES2658168T3/es active Active
- 2010-12-15 KR KR1020127018388A patent/KR20120107493A/ko not_active Ceased
- 2010-12-15 WO PCT/US2010/060439 patent/WO2011084453A1/fr not_active Ceased
- 2010-12-15 CA CA2783468A patent/CA2783468C/fr active Active
- 2010-12-15 JP JP2012544740A patent/JP5634526B2/ja active Active
- 2010-12-15 KR KR1020187022229A patent/KR102029611B1/ko active Active
- 2010-12-15 MX MX2012006725A patent/MX2012006725A/es active IP Right Grant
- 2010-12-15 DK DK10796247.4T patent/DK2513070T3/en active
- 2010-12-15 CN CN201080063893.4A patent/CN102753539B/zh active Active
- 2010-12-15 US US13/515,508 patent/US8912335B2/en active Active
- 2010-12-15 NZ NZ600390A patent/NZ600390A/xx unknown
- 2010-12-15 NO NO10796247A patent/NO2513070T3/no unknown
- 2010-12-15 AU AU2010340055A patent/AU2010340055B2/en active Active
- 2010-12-15 PL PL10796247T patent/PL2513070T3/pl unknown
- 2010-12-15 EP EP10796247.4A patent/EP2513070B1/fr active Active
- 2010-12-15 KR KR1020177010102A patent/KR102029560B1/ko active Active
- 2010-12-15 HU HUE10796247A patent/HUE038042T2/hu unknown
-
2014
- 2014-10-30 US US14/528,163 patent/US9126959B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| DK2513070T3 (en) | 2018-01-22 |
| ES2658168T3 (es) | 2018-03-08 |
| US8912335B2 (en) | 2014-12-16 |
| US20150051406A1 (en) | 2015-02-19 |
| KR102029611B1 (ko) | 2019-10-07 |
| JP5634526B2 (ja) | 2014-12-03 |
| WO2011084453A1 (fr) | 2011-07-14 |
| KR102029560B1 (ko) | 2019-10-07 |
| JP2013514367A (ja) | 2013-04-25 |
| CN102753539A (zh) | 2012-10-24 |
| RU2012129930A (ru) | 2014-01-27 |
| KR20180089569A (ko) | 2018-08-08 |
| MX2012006725A (es) | 2012-06-28 |
| KR20120107493A (ko) | 2012-10-02 |
| CA2783468A1 (fr) | 2011-07-14 |
| HK1174330A1 (en) | 2013-06-07 |
| HUE038042T2 (hu) | 2018-09-28 |
| US20120309975A1 (en) | 2012-12-06 |
| EP2513070B1 (fr) | 2017-11-08 |
| AU2010340055A1 (en) | 2012-06-28 |
| NZ600390A (en) | 2013-08-30 |
| RU2564661C2 (ru) | 2015-10-10 |
| AU2010340055B2 (en) | 2014-07-24 |
| CA2783468C (fr) | 2018-10-09 |
| PL2513070T3 (pl) | 2018-05-30 |
| EP2513070A1 (fr) | 2012-10-24 |
| US9126959B2 (en) | 2015-09-08 |
| KR20170044214A (ko) | 2017-04-24 |
| CN102753539B (zh) | 2015-09-09 |