NO301048B1 - Fremgangsmåte ved fremstilling av et karboplatinpreparat - Google Patents

Fremgangsmåte ved fremstilling av et karboplatinpreparat Download PDF

Info

Publication number: NO301048B1
Authority: NO; Norway
Prior art keywords: carboplatin; preparation; solution; buffered; concentration
Prior art date: 1989-06-06

Application number

NO902488A

Other languages

English (en)

Norwegian (no)

Other versions

NO902488L (no

NO902488D0 (no

Inventor

Alfred James Nijkerk

Johanna Maria Pieterne Vermeer

Original Assignee

Pharmachemie Bv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-06-06

Filing date

1990-06-05

Publication date

1997-09-08

1990-06-05 Application filed by Pharmachemie Bv filed Critical Pharmachemie Bv

1990-06-05 Publication of NO902488D0 publication Critical patent/NO902488D0/no

1990-12-07 Publication of NO902488L publication Critical patent/NO902488L/no

1997-09-08 Publication of NO301048B1 publication Critical patent/NO301048B1/no

Links

190000008236 carboplatin Chemical compound 0.000 title claims abstract description 24
229960004562 carboplatin Drugs 0.000 title claims abstract description 24
238000000034 method Methods 0.000 title claims description 7
239000000243 solution Substances 0.000 claims abstract description 18
239000007864 aqueous solution Substances 0.000 claims abstract description 4
239000000872 buffer Substances 0.000 claims description 4
239000006172 buffering agent Substances 0.000 claims description 4
239000002671 adjuvant Substances 0.000 claims description 2
239000008363 phosphate buffer Substances 0.000 claims description 2
238000004519 manufacturing process Methods 0.000 claims 1
239000000203 mixture Substances 0.000 abstract 1
NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 14
229910000147 aluminium phosphate Inorganic materials 0.000 description 7
229910000403 monosodium phosphate Inorganic materials 0.000 description 5
235000019799 monosodium phosphate Nutrition 0.000 description 5
AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 5
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 description 3
238000003776 cleavage reaction Methods 0.000 description 2
239000000824 cytostatic agent Substances 0.000 description 2
230000007017 scission Effects 0.000 description 2
230000003139 buffering effect Effects 0.000 description 1
239000003795 chemical substances by application Substances 0.000 description 1
230000000694 effects Effects 0.000 description 1
238000004811 liquid chromatography Methods 0.000 description 1
230000007246 mechanism Effects 0.000 description 1
239000002245 particle Substances 0.000 description 1
230000001225 therapeutic effect Effects 0.000 description 1
231100000167 toxic agent Toxicity 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Dermatology (AREA)
Inorganic Chemistry (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Powder Metallurgy (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

NO902488A 1989-06-06 1990-06-05 Fremgangsmåte ved fremstilling av et karboplatinpreparat NO301048B1 (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
NL8901433A NL8901433A (nl)	1989-06-06	1989-06-06	Carboplatinpreparaat.

Publications (3)

Publication Number	Publication Date
NO902488D0 NO902488D0 (no)	1990-06-05
NO902488L NO902488L (no)	1990-12-07
NO301048B1 true NO301048B1 (no)	1997-09-08

Family

ID=19854785

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO902488A NO301048B1 (no)	1989-06-06	1990-06-05	Fremgangsmåte ved fremstilling av et karboplatinpreparat

Country Status (13)

Country	Link
US (1)	US5104896A (fr)
EP (1)	EP0401896B1 (fr)
JP (1)	JP2825934B2 (fr)
AT (1)	ATE92759T1 (fr)
AU (1)	AU630961B2 (fr)
CA (1)	CA2018229C (fr)
DE (1)	DE69002697T2 (fr)
DK (1)	DK0401896T3 (fr)
ES (1)	ES2044405T3 (fr)
FI (1)	FI96276C (fr)
IL (1)	IL94652A (fr)
NL (1)	NL8901433A (fr)
NO (1)	NO301048B1 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5977082A (en) *	1985-08-02	1999-11-02	Pharmacia & Upjohn Company	Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5124317A (en)	1985-08-02	1992-06-23	Farmitalia Carlo Erba S.P.A.	Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5455270A (en) *	1993-08-11	1995-10-03	Bristol-Myers Squibb Co.	Stabilized solutions of platinum(II) antitumor agents
DE69427595T2 (de) *	1994-02-07	2002-04-25	Pliva Pharmaceutical Industry	Antitumormittel auf basis von carboplatin und herstellung desselben
AU2989695A (en) *	1994-08-08	2000-03-07	Debiopharm S.A.	Pharmaceutically stable oxaliplatinum preparation
CZ292170B6 (cs) *	1998-08-14	2003-08-13	Pliva-Lachema A.S.	Farmaceutická kompozice s protinádorovým účinkem na bázi carboplatiny
CN1200750C (zh) *	2000-01-24	2005-05-11	伯恩斯坦股份有限责任公司	优选为雪地或水上的运载工具的运动装置
AUPQ641100A0 (en) *	2000-03-23	2000-04-15	Australia Nuclear Science & Technology Organisation	Methods of synthesis and use of radiolabelled platinum chemotherapeutic ag ents
EP1404689A1 (fr) *	2001-07-02	2004-04-07	Debiopharm S.A.	Substance active a base d'oxaliplatine presentant une faible teneur en acide oxalique
EP1879568B1 (fr) *	2005-03-28	2009-05-06	Dabur Pharma Limited	Preparations pharmaceutiques stables d agents antitumoraux contenant du platine(ii)
US20090130017A1 (en) *	2007-11-19	2009-05-21	Searete Llc	Targeted short-lived drug delivery
KR101127159B1 (ko) *	2009-11-02	2012-03-20	한국생명공학연구원	식물병원성 그람음성 세균의 분비체계를 저해하는 카보프라틴 화합물을 유효성분으로 함유하는 식물병 방제제
KR101055409B1 (ko) *	2010-12-31	2011-08-08	내쇼날씨엔디 주식회사	튜브형 썰매
KR20250137729A (ko)	2015-02-27	2025-09-18	캐논 가부시끼가이샤	드럼 유닛, 카트리지 및 전자 사진 형성 장치
US12427104B1 (en)	2025-04-01	2025-09-30	Ingenus Pharmaceuticals, Llc	Injectable carboplatin formulations

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4339437A (en) *	1976-12-27	1982-07-13	Research Corporation	Anti-tumor method
US4873226A (en) *	1983-06-17	1989-10-10	Delta Metals, Inc.	Method of inhibiting herpetic lesions by the use of platinum coordination compounds
NL8303657A (nl) *	1983-10-24	1985-05-17	Pharmachemie Bv	Voor injectie geschikte, stabiele, waterige, zoutzuur bevattende oplossing van cisplatine, alsmede werkwijze ter bereiding daarvan.
GB8416048D0 (en) *	1984-06-22	1984-07-25	Johnson Matthey Plc	Anti-tumour compounds of platinum
CS269719B1 (en) *	1986-12-29	1990-05-14	Kiss Frantisek	Platinum cytostatic

1989
- 1989-06-06 NL NL8901433A patent/NL8901433A/nl not_active Application Discontinuation
1990
- 1990-05-28 DK DK90201354.9T patent/DK0401896T3/da active
- 1990-05-28 EP EP90201354A patent/EP0401896B1/fr not_active Expired - Lifetime
- 1990-05-28 AT AT90201354T patent/ATE92759T1/de not_active IP Right Cessation
- 1990-05-28 ES ES90201354T patent/ES2044405T3/es not_active Expired - Lifetime
- 1990-05-28 DE DE90201354T patent/DE69002697T2/de not_active Expired - Fee Related
- 1990-05-29 US US07/529,917 patent/US5104896A/en not_active Expired - Lifetime
- 1990-05-31 FI FI902713A patent/FI96276C/fi not_active IP Right Cessation
- 1990-06-04 CA CA002018229A patent/CA2018229C/fr not_active Expired - Fee Related
- 1990-06-05 NO NO902488A patent/NO301048B1/no not_active IP Right Cessation
- 1990-06-05 AU AU56296/90A patent/AU630961B2/en not_active Ceased
- 1990-06-06 JP JP2146385A patent/JP2825934B2/ja not_active Expired - Fee Related
- 1990-06-06 IL IL9465290A patent/IL94652A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0401896B1 (fr)	1993-08-11
ATE92759T1 (de)	1993-08-15
AU630961B2 (en)	1992-11-12
IL94652A (en)	1994-02-27
DK0401896T3 (da)	1993-11-15
EP0401896A1 (fr)	1990-12-12
US5104896A (en)	1992-04-14
FI96276B (fi)	1996-02-29
FI902713A0 (fi)	1990-05-31
CA2018229C (fr)	1998-04-07
DE69002697T2 (de)	1994-02-10
CA2018229A1 (fr)	1990-12-06
JP2825934B2 (ja)	1998-11-18
DE69002697D1 (de)	1993-09-16
IL94652A0 (en)	1991-04-15
AU5629690A (en)	1990-12-13
NO902488L (no)	1990-12-07
JPH0356420A (ja)	1991-03-12
ES2044405T3 (es)	1994-01-01
NO902488D0 (no)	1990-06-05
FI96276C (fi)	1996-06-10
NL8901433A (nl)	1991-01-02

Legal Events

Date	Code	Title	Description
2006-01-30	MM1K	Lapsed by not paying the annual fees

Publication	Publication Date	Title
DE60100143T2 (de)	2003-11-27	Freisetzungssystem von Cyclopropenderivaten, welches eine kleinere Wassermenge benützt
US5104896A (en)	1992-04-14	Carboplatin composition
CN109418289A (zh)	2019-03-05	一种次氯酸钠凝胶及其制备方法
US4097588A (en)	1978-06-27	Mineralizing dental mouthrinse
CZ2002243A3 (cs)	2002-04-17	Oftalmologická kompozice obsahující ketotifen
EP0098073B1 (fr)	1988-12-14	Composition pharmaceutique en poudre, contenant de la myéloperoxidase
US4128397A (en)	1978-12-05	Sulfur dioxide liberation compositions and methods of using same
US4046879A (en)	1977-09-06	Antiviral compositions
JP3118258B2 (ja)	2000-12-18	ジホスホン酸およびその塩を含有する医薬品
Canfield et al.	1973	Equilibrium of nucleotides in frog sartorius muscle during an isometric tetanus at 20° C
US2978385A (en)	1961-04-04	Stabilized chymotrypsin solution
EP0522122B1 (fr)	2001-08-22	Compositions pharmaceutiques contenant de l'amethocaine
Al-Mughrabi et al.	1992	Effect of pH of water from the King Abdallah Canal in Jordan on the stability of cypermethrin
Dowben et al.	1964	Effects of steroids on the course of hereditary muscular dystrophy in mice
CN1289094C (zh)	2006-12-13	三磷酸腺苷盐组合物
JPH03120223A (ja)	1991-05-22	抗ウイルス性医薬用組成物
US2698819A (en)	1955-01-04	Ethylenediamine tetraacetic acid periodides and compositions thereof
JPH07187902A (ja)	1995-07-25	切花活性剤
KR20080042143A (ko)	2008-05-14	안정화 및 보존된 케토티펜 안과 조성물
US2436086A (en)	1948-02-17	Pectic acid compositions
NO173635B (no)	1993-10-04	Fremgangsmaate for fremstilling av en stabil injiserbar opploesning av et antrakinonderivat
Grobecker et al.	1977	Effect of tyramine and guanethidine on dopamine-β-hydroxylase activity and norepinephrine concentrations in vesicular fraction of the heart and plasma of rats
US2778771A (en)	1957-01-22	Stabilizing of vitamin b12 solutions
JPH11504344A (ja)	1999-04-20	ドブタミンを含有する安定化された製薬学的組成物
JPH02304001A (ja)	1990-12-17	植物の保存剤及び保在方法