NO301164B1 - Alkylsubstituerte, heterosykliske forbindelser, anvendelser derav og farmasöytisk preparat som omfatter en slik forbindelse - Google Patents

Alkylsubstituerte, heterosykliske forbindelser, anvendelser derav og farmasöytisk preparat som omfatter en slik forbindelse Download PDF

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Publication number
NO301164B1
NO301164B1 NO934758A NO934758A NO301164B1 NO 301164 B1 NO301164 B1 NO 301164B1 NO 934758 A NO934758 A NO 934758A NO 934758 A NO934758 A NO 934758A NO 301164 B1 NO301164 B1 NO 301164B1
Authority
NO
Norway
Prior art keywords
phenyl
tropane
oxadiazol
alkyl
substituted
Prior art date
Application number
NO934758A
Other languages
English (en)
Norwegian (no)
Other versions
NO934758D0 (no
NO934758L (no
Inventor
Peter Moldt
Joergen Scheel-Krueger
Leif Helth Jensen
Original Assignee
Neurosearch As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK921541A external-priority patent/DK154192D0/da
Application filed by Neurosearch As filed Critical Neurosearch As
Publication of NO934758D0 publication Critical patent/NO934758D0/no
Publication of NO934758L publication Critical patent/NO934758L/no
Publication of NO301164B1 publication Critical patent/NO301164B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO934758A 1992-12-23 1993-12-22 Alkylsubstituerte, heterosykliske forbindelser, anvendelser derav og farmasöytisk preparat som omfatter en slik forbindelse NO301164B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK921541A DK154192D0 (da) 1992-12-23 1992-12-23 Heterocycliske forbindelser
US08/093,181 US5444070A (en) 1992-12-23 1993-07-16 Phenyl substituted heterocyclic compounds
US08/093,183 US5369113A (en) 1992-12-23 1993-07-16 Certain 2,3-diphenyl-2-(1,2,4-oxadiazol-5-yl)tropanes useful as dopamide reuptake inhibitors

Publications (3)

Publication Number Publication Date
NO934758D0 NO934758D0 (no) 1993-12-22
NO934758L NO934758L (no) 1994-06-24
NO301164B1 true NO301164B1 (no) 1997-09-22

Family

ID=27221329

Family Applications (1)

Application Number Title Priority Date Filing Date
NO934758A NO301164B1 (no) 1992-12-23 1993-12-22 Alkylsubstituerte, heterosykliske forbindelser, anvendelser derav og farmasöytisk preparat som omfatter en slik forbindelse

Country Status (13)

Country Link
EP (1) EP0604355B1 (de)
JP (1) JPH06293759A (de)
AT (1) ATE195314T1 (de)
AU (1) AU671163B2 (de)
CA (1) CA2112061C (de)
DE (1) DE69329184T2 (de)
DK (1) DK0604355T3 (de)
ES (1) ES2149193T3 (de)
FI (1) FI935798A7 (de)
GR (1) GR3034746T3 (de)
NO (1) NO301164B1 (de)
NZ (1) NZ250513A (de)
PT (1) PT604355E (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6329520B1 (en) * 1990-08-09 2001-12-11 Research Triangle Institute Cocaine receptor binding ligands
AU672644B2 (en) * 1992-12-23 1996-10-10 Neurosearch A/S Aryl substituted heterocyclic compounds
EE03877B1 (et) * 1994-04-19 2002-10-15 Neurosearch A/S Tropaan-2-aldoksiimi derivaadid neurotransmitteritagasihaarde inhibiitoritena
BR9607841A (pt) * 1995-03-24 1998-06-16 Neurosearch As Método para a preparação de estéres de anidroeggonina
BR9707636A (pt) * 1996-02-22 1999-07-27 Neurosearch As Composto composição farmacêutica uso de um composto e processos para preparar composto e para tratar um distúrbio ou doença de um organismo animal vivo
GB9915617D0 (en) * 1999-07-05 1999-09-01 Knoll Ag Therapeutic agents
US7381733B2 (en) 2001-11-30 2008-06-03 Neurosearch A/S Tropane derivatives having dopamine reuptake inhibitor activity for the treatment of ischemic diseases
EP2269608A3 (de) 2003-10-16 2011-02-16 NeuroSearch AS Pharmazeutische Zusammensetzungen welche Monoamin-Aufnahme-Neurotrransmitter-Reuptake-Inhibitoren und Acetylcholinesterase Inhibitoren enthalten
EP1779851A1 (de) 2005-10-31 2007-05-02 Boehringer Ingelheim Pharma GmbH & Co.KG Behandlung von Diabetes

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3813404A (en) * 1972-11-15 1974-05-28 Sterling Drug Inc Tropane-2-carboxylates and derivatives
FR2276823A1 (fr) * 1974-07-04 1976-01-30 Roussel Uclaf Nouveaux derives de la dibenzo(b.e)thiepine et leurs sels, procede de preparation et application a titre de medicaments desdits produits
NZ219646A (en) * 1986-03-27 1990-10-26 Merck Sharp & Dohme Oxadiazole derivatives of azacyclics for treating cns disorders
IE63906B1 (en) * 1987-11-13 1995-06-14 Novo Nordisk As Azabicyclic compounds and their preparation and use
NZ227684A (en) * 1988-01-30 1991-07-26 Merck Sharp & Dohme Pyrazine, pyridazine, and pyrimidine derivatives and pharmaceutical compositions
ES2098248T3 (es) * 1989-05-17 1997-05-01 Pfizer Derivados de 2-piperidino-1-alcanoles como agentes antiisquemicos.
DK198590D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
DE69233536D1 (de) * 1991-11-15 2005-08-25 Res Triangle Inst Res Triangle Kokainrezeptor bindende Liganden
US5262428A (en) * 1992-03-13 1993-11-16 Wake Forest University Biologically active tropane derivatives
US5268480A (en) * 1992-09-22 1993-12-07 Mayo Foundation For Medical Education And Research Cocaine analogs

Also Published As

Publication number Publication date
NO934758D0 (no) 1993-12-22
PT604355E (pt) 2001-01-31
NZ250513A (en) 1996-03-26
DK0604355T3 (da) 2000-12-04
DE69329184D1 (de) 2000-09-14
CA2112061C (en) 2002-11-19
EP0604355B1 (de) 2000-08-09
DE69329184T2 (de) 2001-04-05
GR3034746T3 (en) 2001-02-28
AU5236193A (en) 1994-07-07
ES2149193T3 (es) 2000-11-01
CA2112061A1 (en) 1994-06-24
EP0604355A3 (de) 1995-02-08
JPH06293759A (ja) 1994-10-21
NO934758L (no) 1994-06-24
FI935798L (fi) 1994-06-24
EP0604355A2 (de) 1994-06-29
FI935798A7 (fi) 1994-06-24
AU671163B2 (en) 1996-08-15
ATE195314T1 (de) 2000-08-15
FI935798A0 (fi) 1993-12-22

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Free format text: LAPSED IN JUNE 2003