NO301284B1 - Fremgangsmåte for fremstilling av et ikke naturlig forekommende pseudorabiesvirus, samt fremgangsmåte for in vitro bestemmelse av hvorvidt et vaksinert dyr er blitt smittet med et virulent pseudorabiesvirus av villtype - Google Patents

Fremgangsmåte for fremstilling av et ikke naturlig forekommende pseudorabiesvirus, samt fremgangsmåte for in vitro bestemmelse av hvorvidt et vaksinert dyr er blitt smittet med et virulent pseudorabiesvirus av villtype Download PDF

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Publication number
NO301284B1
NO301284B1 NO871313A NO871313A NO301284B1 NO 301284 B1 NO301284 B1 NO 301284B1 NO 871313 A NO871313 A NO 871313A NO 871313 A NO871313 A NO 871313A NO 301284 B1 NO301284 B1 NO 301284B1
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Norway
Prior art keywords
virus
prv
gene
fragment
plasmid
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NO871313A
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English (en)
Norwegian (no)
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NO871313D0 (no
NO871313L (no
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Leonard E Post
Darrell R Thomsen
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Upjohn Co
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Publication of NO871313D0 publication Critical patent/NO871313D0/no
Publication of NO871313L publication Critical patent/NO871313L/no
Publication of NO301284B1 publication Critical patent/NO301284B1/no

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/245—Herpetoviridae, e.g. herpes simplex virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16721—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16722—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/826—Viruses

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Plant Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pathology (AREA)
NO871313A 1985-07-29 1987-03-27 Fremgangsmåte for fremstilling av et ikke naturlig forekommende pseudorabiesvirus, samt fremgangsmåte for in vitro bestemmelse av hvorvidt et vaksinert dyr er blitt smittet med et virulent pseudorabiesvirus av villtype NO301284B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76013085A 1985-07-29 1985-07-29
PCT/US1986/001322 WO1987000862A1 (en) 1985-07-29 1986-06-17 Virus vaccine

Publications (3)

Publication Number Publication Date
NO871313D0 NO871313D0 (no) 1987-03-27
NO871313L NO871313L (no) 1987-03-27
NO301284B1 true NO301284B1 (no) 1997-10-06

Family

ID=25058182

Family Applications (1)

Application Number Title Priority Date Filing Date
NO871313A NO301284B1 (no) 1985-07-29 1987-03-27 Fremgangsmåte for fremstilling av et ikke naturlig forekommende pseudorabiesvirus, samt fremgangsmåte for in vitro bestemmelse av hvorvidt et vaksinert dyr er blitt smittet med et virulent pseudorabiesvirus av villtype

Country Status (18)

Country Link
US (1) US4810634A (de)
EP (1) EP0231209B1 (de)
JP (2) JP2559384B2 (de)
KR (1) KR950000887B1 (de)
CN (1) CN1018845B (de)
AT (1) ATE60799T1 (de)
AU (1) AU591145B2 (de)
CA (1) CA1275625C (de)
DE (1) DE3677494D1 (de)
DK (1) DK170948B1 (de)
ES (1) ES2001752A6 (de)
FI (1) FI871362A0 (de)
HK (1) HK32696A (de)
IE (1) IE59087B1 (de)
NO (1) NO301284B1 (de)
PH (1) PH25776A (de)
WO (1) WO1987000862A1 (de)
ZA (1) ZA865277B (de)

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US5041536A (en) * 1984-05-02 1991-08-20 The Upjohn Company Pseudorabies virus (PRV) gene
US5275934A (en) * 1985-07-29 1994-01-04 The Upjohn Company Method of detecting viral infection in vaccinated animals
EP0263207B1 (de) * 1986-10-08 1991-11-27 The Upjohn Company Virus-Vakzin
US5128128A (en) * 1985-07-29 1992-07-07 The Upjohn Company Virus vaccine
US5068192A (en) * 1986-01-27 1991-11-26 Prutech Research And Development Partnership Attenuated pseudorabies virus which includes foreign DNA encoding an amino acid sequence
US5763269A (en) * 1985-09-06 1998-06-09 Syntro Corporation Recombinant infectious bovine rhinotrocheitis virus
US5047237A (en) * 1985-09-06 1991-09-10 Prutech Research And Development Partnership Attenuated pseudorabies virus having a deletion of at least a portion of a gene encoding an antigenic, nonessential protein, vaccine containing same and methods of identifying animals vaccinated with the vaccine
WO1987002058A1 (en) * 1985-10-04 1987-04-09 The Upjohn Company Pseudorabies virus protein
US5352575A (en) * 1985-10-04 1994-10-04 The Upjohn Company Pseudorabies virus protein
US5593873A (en) * 1986-01-27 1997-01-14 Syntro Corporation Recombinant infectious bovine rhinotracheitis virus
EP0256092B1 (de) * 1986-01-27 1998-04-08 Syntro Corporation Abgeschwächte herpesviren, herpesviren, die eine für aminosäuresequenzen kodierende fremd-dns enthalten, sowie impfstoffe, die diese enthalten
US6172186B1 (en) 1986-03-26 2001-01-09 Pharmacia & Upjohn Company Pseudorabies virus protein
FR2601689B1 (fr) * 1986-07-17 1992-10-16 Syntro Corp Herpes virus attenues, herpes virus qui renferment de l'adn etranger codant pour une sequence d'amino-acides, et vaccins les contenant
US5037742A (en) * 1986-07-18 1991-08-06 E. I. Du Pont De Nemours And Company Pseudorabies virus recombinants and their use in the production of proteins
US5004693A (en) * 1986-07-18 1991-04-02 E. I. Du Pont De Nemours And Company Pseudorabies virus recombinants and their use in the production of proteins
AU619181B2 (en) * 1987-03-19 1992-01-23 Synergen, Inc. Viral vector system for the introduction of foreign dna expression products into gallinaceous birds
US5273876A (en) * 1987-06-26 1993-12-28 Syntro Corporation Recombinant human cytomegalovirus containing foreign gene
US5783195A (en) * 1991-07-18 1998-07-21 Syntro Corporation Recombinant infectious bovine rhinotracheitis virus S-IBR-052 and uses thereof
EP0658623A3 (de) * 1987-07-27 1995-09-27 Syntro Corp Attenuierte Herpesviren, Herpesvirein, die eine Aminosäuresequenz kodierende fremde DNS beeinhalten, und sie enthaltende Impstoffe.
US5128129A (en) * 1987-11-03 1992-07-07 Novagene Inc. Infectious bovine rhinotrachetis virus mutants, vaccines containing same, methods for the production of same and methods for the use of same
US4992051A (en) * 1987-11-03 1991-02-12 Novagene, Inc. Infectious bovine rhinotracheitis virus mutants, methods for the production of same and methods for the use of same
US5069901A (en) * 1988-02-03 1991-12-03 Jones Elaine V Preparation of a recombinant subunit vaccine against pseudorabies infection
JP2779447B2 (ja) * 1988-03-20 1998-07-23 財団法人阪大微生物病研究会 弱毒マレック病ウイルス・ベクターを用いる組換え遺伝子作成法、及び該ウイルスの組換え体
JP2583115B2 (ja) * 1988-09-10 1997-02-19 財団法人化学及血清療法研究所 組換えマレック病ウイルスおよびその製法
US5122447A (en) * 1989-01-23 1992-06-16 Iowa State University Research Foundation, Inc. Method of detecting pseudorabies virus specific serum antibody by use of a universal diagnostic antigen
US5240703A (en) * 1991-03-01 1993-08-31 Syntro Corporation Attenuated, genetically-engineered pseudorabies virus s-prv-155 and uses thereof
WO1993002104A1 (en) * 1991-07-18 1993-02-04 Syntro Corporation Recombinant infectious bovine rhinotracheitis virus
US5874279A (en) * 1991-07-18 1999-02-23 Syntro Corporation Recombinant infectious bovine rhinotracheitis virus
WO1993024147A1 (en) * 1992-05-29 1993-12-09 Smithkline Beecham Corporation Lecithin adjuvanted modified live virus vaccines
TW289731B (de) * 1992-07-09 1996-11-01 Akzo Nv
ATE227775T1 (de) * 1992-07-30 2002-11-15 Akzo Nobel Nv Impfstoff-vektoren von rekombinantem katzen- herpesvirus
US5738854A (en) * 1992-10-06 1998-04-14 Akzo Nobel N.V. Pseudorabies virus vaccine
EP0619840A1 (de) * 1992-10-06 1994-10-19 Akzo Nobel N.V. Pseudotollwutvirus-impfstoff
ES2074965B1 (es) * 1994-01-31 1996-05-01 Hipra Lab Sa Virus mutante recombinante de rinotraqueitis infecciosa bovina y vacunas que lo contienen.
HU220746B1 (hu) * 1994-06-17 2002-05-28 Instituut Voor Veehouderij En Diergezondheid Pestivírustörzsekből izolált nukleotidszekvenciák, az általuk kódolt polipeptidek és ezek alkalmazása pestivírus-fertőzések diagnosztizálására és megelőzésére
US6284251B1 (en) 1996-02-26 2001-09-04 Kansas State University Research Foundation BHV-1 gene-deleted virus vaccine
GB0126047D0 (en) * 2001-10-30 2001-12-19 Univ Cambridge Tech Therapeutic molecules
US10918712B2 (en) 2014-03-03 2021-02-16 Albert Einstein College Of Medicine Passive transfer of immunity using recombinant herpes simplex virus 2 (HSV-2) vaccine vectors
WO2015134368A2 (en) 2014-03-03 2015-09-11 Albert Einstein College Of Medicine Of Yeshiva University Recombinant herpes simplex virus 2 (hsv-2) vaccine vectors
WO2017106736A1 (en) * 2015-12-18 2017-06-22 Louisiana State University Research & Technology Foundation Pseudorabies virus (prv) vector expressing heterologous polypeptides
US12098166B2 (en) 2018-11-06 2024-09-24 Boehringer Ingelheim Vetmedica Gmbh Immunogenic composition against avian influenza virus H5 subtype

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US4603112A (en) * 1981-12-24 1986-07-29 Health Research, Incorporated Modified vaccinia virus
NL8303501A (nl) * 1983-10-12 1985-05-01 Centraal Diergeneeskundig Inst Deletiemutant van een herpesvirus en vaccin, dat dit virus bevat.
US4514497B1 (en) * 1983-12-30 1998-02-24 Novagene Inc Modified live pseudorabies viruses
US4703011A (en) * 1985-11-12 1987-10-27 Novagene, Inc. Thymidine kinase deletion mutants of bovine herpesvirus-1
US4711850A (en) * 1986-01-28 1987-12-08 Novagene, Inc. Pseudorabies virus mutants, vaccines containing same, methods for the production of same and methods for the use of same

Also Published As

Publication number Publication date
US4810634A (en) 1989-03-07
AU591145B2 (en) 1989-11-30
KR950000887B1 (ko) 1995-02-03
FI871362A7 (fi) 1987-03-27
ZA865277B (en) 1987-03-25
CA1275625C (en) 1990-10-30
JPH08333279A (ja) 1996-12-17
AU5994886A (en) 1987-03-05
ES2001752A6 (es) 1988-06-16
PH25776A (en) 1991-10-18
IE59087B1 (en) 1994-01-12
FI871362L (fi) 1987-03-27
CN86105450A (zh) 1987-03-04
DK157087A (da) 1987-03-27
EP0231209A1 (de) 1987-08-12
DK157087D0 (da) 1987-03-27
DK170948B1 (da) 1996-03-25
FI871362A0 (fi) 1987-03-27
ATE60799T1 (de) 1991-02-15
CN1018845B (zh) 1992-10-28
JP2559384B2 (ja) 1996-12-04
JP2738524B2 (ja) 1998-04-08
IE861996L (en) 1987-01-29
DE3677494D1 (de) 1991-03-14
EP0231209B1 (de) 1991-02-06
HK32696A (en) 1996-03-01
KR880700070A (ko) 1988-02-15
WO1987000862A1 (en) 1987-02-12
JPS63500449A (ja) 1988-02-18
NO871313D0 (no) 1987-03-27
NO871313L (no) 1987-03-27

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