NO302471B1 - Tiazolidinforbindelser og farmasöytisk preparat - Google Patents

Tiazolidinforbindelser og farmasöytisk preparat

Info

Publication number: NO302471B1
Authority: NO; Norway
Prior art keywords: alkyl; hydrogen; pharmaceutical preparations; optionally substituted; thiazolidine compounds
Prior art date: 1991-12-26

Application number

NO924964A

Other languages

English (en)

Norwegian (no)

Other versions

NO924964L (no

NO924964D0 (no

Inventor

Takao Yoshioka

Takahide Nishi

Tsutomu Kanai

Yuichi Aizawa

Kunio Wada

Takashi Fujita

Hiroyoshi Horikoshi

Original Assignee

Sankyo Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-12-26

Filing date

1992-12-22

Publication date

1998-03-09

1992-12-22 Application filed by Sankyo Co filed Critical Sankyo Co

1992-12-22 Publication of NO924964D0 publication Critical patent/NO924964D0/no

1993-06-28 Publication of NO924964L publication Critical patent/NO924964L/no

1998-03-09 Publication of NO302471B1 publication Critical patent/NO302471B1/no

Links

239000000825 pharmaceutical preparation Substances 0.000 title 1
150000003548 thiazolidines Chemical class 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 4
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
150000002431 hydrogen Chemical class 0.000 abstract 3
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
-1 pyridine-carbonyl Chemical group 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000002947 alkylene group Chemical group 0.000 abstract 1
230000003178 anti-diabetic effect Effects 0.000 abstract 1
125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
239000011203 carbon fibre reinforced carbon Substances 0.000 abstract 1
150000001768 cations Chemical class 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000001038 naphthoyl group Chemical group C1(=CC=CC2=CC=CC=C12)C(=O)* 0.000 abstract 1
230000000069 prophylactic effect Effects 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Diabetes (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Hematology (AREA)
Obesity (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Steroid Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

NO924964A 1991-12-26 1992-12-22 Tiazolidinforbindelser og farmasöytisk preparat NO302471B1 (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP34457191		1991-12-26

Publications (3)

Publication Number	Publication Date
NO924964D0 NO924964D0 (no)	1992-12-22
NO924964L NO924964L (no)	1993-06-28
NO302471B1 true NO302471B1 (no)	1998-03-09

Family

ID=18370304

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO924964A NO302471B1 (no)	1991-12-26	1992-12-22	Tiazolidinforbindelser og farmasöytisk preparat

Country Status (21)

Country	Link
EP (1)	EP0549365B1 (fr)
JP (1)	JP2833949B2 (fr)
CN (1)	CN1032751C (fr)
AT (1)	ATE126221T1 (fr)
AU (1)	AU654223B2 (fr)
CA (1)	CA2086277A1 (fr)
CZ (1)	CZ389792A3 (fr)
DE (1)	DE69204041T2 (fr)
DK (1)	DK0549365T3 (fr)
ES (1)	ES2078671T3 (fr)
FI (1)	FI925849A7 (fr)
GR (1)	GR3017632T3 (fr)
HK (1)	HK196095A (fr)
HU (1)	HU215450B (fr)
IL (1)	IL104238A (fr)
MX (1)	MX9207595A (fr)
NO (1)	NO302471B1 (fr)
NZ (1)	NZ245612A (fr)
RU (1)	RU2095354C1 (fr)
TW (1)	TW211007B (fr)
ZA (1)	ZA9210021B (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NO302519B1 (no) *	1991-12-26	1998-03-16	Sankyo Co	Tiazolidinforbindelser som inneholder en kinongruppe, og farmasöytisk preparat
CZ289317B6 (cs) *	1994-04-11	2002-01-16	Sankyo Company Limited	Heterocyklická sloučenina, farmaceutický prostředek ji obsahující a její pouľití
EP0783888A1 (fr)	1995-12-26	1997-07-16	Sankyo Company Limited	Utilisation de la troglitazone et de thiazolidinediones apparentées dans la fabrication d'un médicament destiné au traitement et la prévention de l'ostéoporose
US6331633B1 (en) *	1998-05-08	2001-12-18	Calyx Therapeutics Inc.	Heterocyclic analogs of diphenylethylene compounds
DE19828114A1 (de) *	1998-06-24	2000-01-27	Probiodrug Ges Fuer Arzneim	Produgs instabiler Inhibitoren der Dipeptidyl Peptidase IV
DE19828113A1 (de) *	1998-06-24	2000-01-05	Probiodrug Ges Fuer Arzneim	Prodrugs von Inhibitoren der Dipeptidyl Peptidase IV
DE19926233C1 (de) *	1999-06-10	2000-10-19	Probiodrug Ges Fuer Arzneim	Verfahren zur Herstellung von Thiazolidin
US6620830B2 (en)	2000-04-21	2003-09-16	Pfizer, Inc.	Thyroid receptor ligands
ATE310733T1 (de) *	2000-04-21	2005-12-15	Pfizer Prod Inc	Thyroid-rezeptorliganden
JP2003531200A (ja) *	2000-04-24	2003-10-21	アリックスセラピューティクス	糖尿病、高脂血症、高コレステロール血症、およびアテローム性動脈硬化症の治療のための材料と方法
US6768008B2 (en)	2000-04-24	2004-07-27	Aryx Therapeutics	Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
US6680387B2 (en)	2000-04-24	2004-01-20	Aryx Therapeutics	Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
JP2003040877A (ja) *	2001-07-24	2003-02-13	Sumika Fine Chemicals Co Ltd	５−［６−（２−フルオロベンジルオキシ）−２−ナフチル］メチル−２，４−チアゾリジンジオンの製造方法及びその精製方法
ES2388555T3 (es)	2006-03-16	2012-10-16	Metabolic Solutions Development Company Llc	Análogos de tiazolidindiona
CA2646207C (fr)	2006-03-16	2016-01-19	Metabolic Solutions Development Company	Analogues de la thiazolidinedione
NZ597381A (en) *	2007-09-14	2013-03-28	Metabolic Solutions Dev Co Llc	Thiazolidinedione analogues for the treatment of diabetes and inflammatory diseases
US8304441B2 (en)	2007-09-14	2012-11-06	Metabolic Solutions Development Company, Llc	Thiazolidinedione analogues for the treatment of metabolic diseases
HUE038042T2 (hu)	2009-12-15	2018-09-28	Cirius Therapeutics Inc	PPAR helyettesítõ tiazolidindion sók metabolikus betegségek kezelésére
EP2560956B1 (fr) *	2010-04-19	2016-10-26	Octeta Therapeutics, LLC	Nouvelle synthèse de thiazolidinediones
AU2011242844A1 (en) *	2010-04-21	2012-11-01	Metabolic Solutions Development Company, Llc	Thiazolidinedione analogues
HUE031424T2 (en)	2010-08-10	2017-07-28	Octeta Therapeutics Llc	New synthesis of thiazolidinedione compounds
CN115433144B (zh) *	2022-10-09	2023-09-19	燃点(南京)生物医药科技有限公司	一种脂肪酸酯类化合物及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5522636A (en) *	1978-08-04	1980-02-18	Takeda Chem Ind Ltd	Thiazoliding derivative
JPS6051189A (ja) *	1983-08-30	1985-03-22	Sankyo Co Ltd	チアゾリジン誘導体およびその製造法
JPH06779B2 (ja) *	1985-06-10	1994-01-05	武田薬品工業株式会社	チアゾリジオン誘導体およびそれを含んでなる医薬組成物
US5143930A (en) *	1990-02-07	1992-09-01	Sankyo Company, Limited	Thiazolidine derivatives with anti-diabetic activity, their preparation and their use
NO302519B1 (no) *	1991-12-26	1998-03-16	Sankyo Co	Tiazolidinforbindelser som inneholder en kinongruppe, og farmasöytisk preparat

1992
- 1992-12-22 NO NO924964A patent/NO302471B1/no unknown
- 1992-12-23 ZA ZA9210021A patent/ZA9210021B/xx unknown
- 1992-12-23 HU HUP9204130A patent/HU215450B/hu not_active IP Right Cessation
- 1992-12-23 FI FI925849A patent/FI925849A7/fi not_active Application Discontinuation
- 1992-12-23 NZ NZ245612A patent/NZ245612A/en unknown
- 1992-12-24 CA CA002086277A patent/CA2086277A1/fr not_active Abandoned
- 1992-12-24 TW TW081110354A patent/TW211007B/zh active
- 1992-12-24 DE DE69204041T patent/DE69204041T2/de not_active Expired - Fee Related
- 1992-12-24 AT AT92311813T patent/ATE126221T1/de not_active IP Right Cessation
- 1992-12-24 EP EP92311813A patent/EP0549365B1/fr not_active Expired - Lifetime
- 1992-12-24 ES ES92311813T patent/ES2078671T3/es not_active Expired - Lifetime
- 1992-12-24 DK DK92311813.7T patent/DK0549365T3/da active
- 1992-12-24 AU AU30431/92A patent/AU654223B2/en not_active Ceased
- 1992-12-25 JP JP4346122A patent/JP2833949B2/ja not_active Expired - Fee Related
- 1992-12-25 IL IL10423892A patent/IL104238A/en not_active IP Right Cessation
- 1992-12-25 RU RU9292016231A patent/RU2095354C1/ru active
- 1992-12-26 CN CN92115234A patent/CN1032751C/zh not_active Expired - Fee Related
- 1992-12-28 MX MX9207595A patent/MX9207595A/es not_active IP Right Cessation
- 1992-12-28 CZ CS923897A patent/CZ389792A3/cs unknown
1995
- 1995-10-04 GR GR950402745T patent/GR3017632T3/el unknown
- 1995-12-28 HK HK196095A patent/HK196095A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
CN1032751C (zh)	1996-09-11
DE69204041T2 (de)	1996-03-28
HUT67788A (en)	1995-04-28
EP0549365B1 (fr)	1995-08-09
ZA9210021B (en)	1993-07-02
CZ389792A3 (en)	1994-01-19
NO924964L (no)	1993-06-28
IL104238A (en)	1996-10-31
DK0549365T3 (da)	1995-12-18
TW211007B (fr)	1993-08-11
HU9204130D0 (en)	1993-04-28
AU654223B2 (en)	1994-10-27
FI925849A0 (fi)	1992-12-23
JPH05239041A (ja)	1993-09-17
AU3043192A (en)	1993-07-01
HK196095A (en)	1996-01-05
FI925849A7 (fi)	1993-06-27
HU215450B (hu)	1999-04-28
EP0549365A1 (fr)	1993-06-30
GR3017632T3 (en)	1996-01-31
RU2095354C1 (ru)	1997-11-10
DE69204041D1 (de)	1995-09-14
MX9207595A (es)	1994-06-30
NO924964D0 (no)	1992-12-22
ES2078671T3 (es)	1995-12-16
CA2086277A1 (fr)	1993-06-27
ATE126221T1 (de)	1995-08-15
CN1074680A (zh)	1993-07-28
JP2833949B2 (ja)	1998-12-09
NZ245612A (en)	1994-06-27

Publication	Publication Date	Title
DK0549365T3 (da)	1995-12-18	Thiazolidinforbindelser, deres fremstilling og deres terapeutiske anvendelser
DK91889D0 (da)	1989-02-27	5-lipoxygenaseinhiberende 4-(4-phenyl-1-piperazinyl)phenoler
NO932607D0 (no)	1993-07-19	Piperidinderivater og anvendelse av disse
NO302519B1 (no)	1998-03-16	Tiazolidinforbindelser som inneholder en kinongruppe, og farmasöytisk preparat
RU92016231A (ru)	1995-05-20	Тиазолидиновые соединения, способ их получения, фармацевтическая композиция и способ лечения
RU92016230A (ru)	1995-06-19	Тиазолидиновые соединения, фармацевтическая композиция, способ лечения и способы получения соединений
DK39286D0 (da)	1986-01-27	Imidazolderivater, fremgangsmaade til fremstilling heraf og farmaceutiske praeparater indeholdende disse derivater
NO930669D0 (no)	1993-02-25	Tropolonderivater og farmasoeytisk preparat derav for forhindring og behandling av ischemiske sykdommer
NZ246598A (en)	1997-08-22	Trazodone derivatives; compounds and preparation, pharmaceutical compositions; intermediate compounds
DK283189A (da)	1989-12-11	Phenothiazinderivater, deres fremstilling og farmaceutiske praeparater deraf
NO893039D0 (no)	1989-07-26	Bruk av imidazopyrazol-derivater som analgesiske og antiinflammatoriske midler.
DK0418990T3 (da)	1994-03-14	13-brom- og 13,14-dibrom-ergoliner, deres fremstilling og anvendelse i lægemidler
ATE56440T1 (de)	1990-09-15	6-oxo-pyridazinyl-verbindungen.
FI920403A0 (fi)	1992-01-29	Uppteckningsmaterial.
IL66208A0 (en)	1982-11-30	Phenethyl derivatives of thiazole,their preparation and pharmaceutical compositions containing them
BR9706491A (pt)	1999-05-18	Compostos de elipticina processo para a sua preparação e composições farmacêuticas contendo os mesmos