NO302595B1 - Fremgangsmåte og apparat for deteksjon av en ligand - Google Patents

Fremgangsmåte og apparat for deteksjon av en ligand Download PDF

Info

Publication number
NO302595B1
NO302595B1 NO890673A NO890673A NO302595B1 NO 302595 B1 NO302595 B1 NO 302595B1 NO 890673 A NO890673 A NO 890673A NO 890673 A NO890673 A NO 890673A NO 302595 B1 NO302595 B1 NO 302595B1
Authority
NO
Norway
Prior art keywords
surface layer
refractive index
optical structure
substrate
ligand
Prior art date
Application number
NO890673A
Other languages
English (en)
Norwegian (no)
Other versions
NO890673L (no
NO890673D0 (no
Inventor
Craig George Sawyers
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems filed Critical Applied Research Systems
Publication of NO890673D0 publication Critical patent/NO890673D0/no
Publication of NO890673L publication Critical patent/NO890673L/no
Publication of NO302595B1 publication Critical patent/NO302595B1/no

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G01N21/774—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the reagent being on a grating or periodic structure
    • G01N21/7743—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the reagent being on a grating or periodic structure the reagent-coated grating coupling light in or out of the waveguide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Plasma & Fusion (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
NO890673A 1987-06-20 1989-02-17 Fremgangsmåte og apparat for deteksjon av en ligand NO302595B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878714503A GB8714503D0 (en) 1987-06-20 1987-06-20 Detector
PCT/GB1988/000471 WO1988010418A1 (en) 1987-06-20 1988-06-17 Waveguide sensor

Publications (3)

Publication Number Publication Date
NO890673D0 NO890673D0 (no) 1989-02-17
NO890673L NO890673L (no) 1989-04-17
NO302595B1 true NO302595B1 (no) 1998-03-23

Family

ID=10619287

Family Applications (1)

Application Number Title Priority Date Filing Date
NO890673A NO302595B1 (no) 1987-06-20 1989-02-17 Fremgangsmåte og apparat for deteksjon av en ligand

Country Status (6)

Country Link
EP (1) EP0321523B1 (de)
JP (1) JP2572829B2 (de)
CA (1) CA1302875C (de)
GB (1) GB8714503D0 (de)
NO (1) NO302595B1 (de)
WO (1) WO1988010418A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4033912C2 (de) * 1990-10-25 1995-05-24 Fraunhofer Ges Forschung Optischer Sensor
SE501108C2 (sv) * 1993-04-08 1994-11-14 Pharmacia Lkb Biotech Sätt och anordning för bestämning av brytningsindex
US5814565A (en) 1995-02-23 1998-09-29 University Of Utah Research Foundation Integrated optic waveguide immunosensor
US6611634B2 (en) 1996-03-19 2003-08-26 University Of Utah Research Foundation Lens and associatable flow cell
US5925878A (en) * 1997-08-20 1999-07-20 Imation Corp. Diffraction anomaly sensor having grating coated with protective dielectric layer
US5955378A (en) * 1997-08-20 1999-09-21 Challener; William A. Near normal incidence optical assaying method and system having wavelength and angle sensitivity
US5994150A (en) 1997-11-19 1999-11-30 Imation Corp. Optical assaying method and system having rotatable sensor disk with multiple sensing regions
US5986762A (en) * 1998-06-15 1999-11-16 Imation Corp. Optical sensor having optimized surface profile
US6320991B1 (en) 1998-10-16 2001-11-20 Imation Corp. Optical sensor having dielectric film stack
US7218802B1 (en) 2005-11-30 2007-05-15 Corning Incorporated Low drift planar waveguide grating sensor and method for manufacturing same
CN103471997A (zh) * 2013-08-12 2013-12-25 浙江工业大学 基于狭缝波导的血糖检测装置
CN103558155B (zh) * 2013-08-12 2016-08-10 浙江工业大学 一种基于狭缝波导的非疾病诊断和治疗目的的血糖检测方法
CN109803762B (zh) * 2016-10-07 2022-04-01 勃林格殷格翰维特梅迪卡有限公司 用于控制分析装置和分析系统的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1237645A (en) * 1982-12-21 1988-06-07 John H. Fisher Assay technique
AT383684B (de) * 1984-09-17 1987-08-10 Avl Verbrennungskraft Messtech Anordnung zur fluoreszenzoptischen messung von stoffkonzentrationen in einer probe
GB8509491D0 (en) * 1985-04-12 1985-05-15 Plessey Co Plc Optic waveguide biosensors

Also Published As

Publication number Publication date
JP2572829B2 (ja) 1997-01-16
WO1988010418A1 (en) 1988-12-29
GB8714503D0 (en) 1987-07-22
NO890673L (no) 1989-04-17
NO890673D0 (no) 1989-02-17
JPH02500686A (ja) 1990-03-08
CA1302875C (en) 1992-06-09
EP0321523A1 (de) 1989-06-28
EP0321523B1 (de) 1992-12-02

Similar Documents

Publication Publication Date Title
US5344784A (en) Fluorescent assay and sensor therefor
US5478755A (en) Long range surface plasma resonance immunoassay
JP3458860B2 (ja) サンドイッチ分析用センサ装置
JP3535158B2 (ja) 消失性波光学的バイオセンサ分析における測定精度の向上方法
US6093536A (en) Wood's anomaly assay technique and kit
US5830766A (en) Enhanced signal-to-noise ratio and sensitivity optical immunoassay
JP2803877B2 (ja) 巨大分子の特性決定法
FI76432C (fi) Foerfarande och anordning foer bestaemning av element i loesning med en ljusledare.
NO178708B (no) Bölgeleder-sensor
EP0321523B1 (de) Wellenleitersensor
JPS63277969A (ja) 回折イムノアツセイおよび試薬
CA1339005C (en) Method of assay
JP2002357543A (ja) 分析素子、並びにそれを用いた試料の分析方法
EP0500611A1 (de) Analytische vorrichtung und verfahren.
JP4068148B2 (ja) アッセイ法
AU615928B2 (en) Waveguide sensor
JPH11218491A (ja) 光導波路表面上にしみ出したエバネッセント光の強度分布を測定する方法
Hirowatari et al. Slot ring biosensors using silicon nitride waveguides with small temperature coefficient
Boiarski et al. Integrated optic immunoassay for virus detection
NO161945B (no) Fremgangsmaate og apparat for bestemmelse av stoffer i opploesning med en optisk boelgeleder.

Legal Events

Date Code Title Description
MK1K Patent expired