NO302709B1 - Fremgangsmåte ved forbedret produksjon av et polypeptid i en vertscelle - Google Patents

Fremgangsmåte ved forbedret produksjon av et polypeptid i en vertscelle Download PDF

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Publication number: NO302709B1
Authority: NO; Norway
Prior art keywords: smc; dna; polypeptide; dna sequences; expression
Prior art date: 1985-03-26

Application number

NO864724A

Other languages

English (en)

Norwegian (no)

Other versions

NO864724L (no

Inventor

Gary N Buell

Nageswararao Movva

Original Assignee

Biogen Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-03-26

Filing date

1986-11-25

Publication date

1998-04-14

1986-11-25 Application filed by Biogen Inc filed Critical Biogen Inc

1987-01-23 Publication of NO864724L publication Critical patent/NO864724L/no

1998-04-14 Publication of NO302709B1 publication Critical patent/NO302709B1/no

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238000013377 clone selection method Methods 0.000 description 1
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230000002950 deficient Effects 0.000 description 1
238000006209 dephosphorylation reaction Methods 0.000 description 1
238000011161 development Methods 0.000 description 1
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238000000825 ultraviolet detection Methods 0.000 description 1
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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Biomedical Technology (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Molecular Biology (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Plant Pathology (AREA)
Physics & Mathematics (AREA)
Microbiology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Toxicology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Diabetes (AREA)
Endocrinology (AREA)
General Chemical & Material Sciences (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Saccharide Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Compounds Of Unknown Constitution (AREA)

NO864724A 1985-03-26 1986-11-25 Fremgangsmåte ved forbedret produksjon av et polypeptid i en vertscelle NO302709B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB858507833A GB8507833D0 (en)	1985-03-26	1985-03-26	Production of human somatomedin c
PCT/US1986/000579 WO1986005810A1 (en)	1985-03-26	1986-03-25	Production of human somatomedin c

Publications (2)

Publication Number	Publication Date
NO864724L NO864724L (no)	1987-01-23
NO302709B1 true NO302709B1 (no)	1998-04-14

Family

ID=10576658

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO864724A NO302709B1 (no)	1985-03-26	1986-11-25	Fremgangsmåte ved forbedret produksjon av et polypeptid i en vertscelle

Country Status (14)

Country	Link
EP (1)	EP0215110B1 (de)
JP (4)	JPH0691832B2 (de)
CN (1)	CN1034588C (de)
AT (1)	ATE87977T1 (de)
AU (1)	AU594950B2 (de)
CA (1)	CA1339305C (de)
DE (1)	DE3688225T2 (de)
DK (1)	DK175223B1 (de)
ES (1)	ES8705921A1 (de)
GB (1)	GB8507833D0 (de)
IL (1)	IL78278A0 (de)
NO (1)	NO302709B1 (de)
WO (1)	WO1986005810A1 (de)
ZA (1)	ZA862240B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ221789A (en) *	1986-09-12	1991-05-28	Genentech Inc	Recombinant prorelaxin, its preparation and pharmaceutical compositions comprising it
GB8712540D0 (en) *	1987-05-28	1987-07-01	Ucb Sa	Expression of human proapolipoprotein a-i
US4876242A (en) *	1987-09-21	1989-10-24	Merck & Co., Inc.	Human insulin-like growth factor analoges with reduced binding to serum carrier proteins and their production in yeast
AUPP807899A0 (en)	1999-01-08	1999-02-04	University Of Queensland, The	Codon utilization
JP6018719B1 (ja) *	2016-03-15	2016-11-02	Ｂｘ新生精機株式会社	シャッター開閉機の巻上装置

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3486491T2 (de) *	1983-04-25	2003-01-16	Chiron Corp., Emeryville	Hybrid-DNS-Synthesis von reifen insulinähnlichen Wachstumsfaktoren
IL71991A (en) *	1983-06-06	1994-05-30	Genentech Inc	Preparation of human FGI and FGE in their processed form through recombinant AND tranology in prokaryotes
SE8303626D0 (sv) *	1983-06-23	1983-06-23	Kabigen Ab	A recombinant plasmid a transformant microorganism, a polydoxyrebonucleotide segment, a process for producing a biologically active protein, and the protein thus produced
EP0151760A1 (de) *	1984-01-06	1985-08-21	Takeda Chemical Industries, Ltd.	DNA und ihre Verwendung
US4758512A (en) *	1984-03-06	1988-07-19	President And Fellows Of Harvard College	Hosts and methods for producing recombinant products in high yields

1985
- 1985-03-26 GB GB858507833A patent/GB8507833D0/en active Pending
1986
- 1986-03-21 CA CA000504757A patent/CA1339305C/en not_active Expired - Lifetime
- 1986-03-25 ES ES553374A patent/ES8705921A1/es not_active Expired
- 1986-03-25 DE DE8686902217T patent/DE3688225T2/de not_active Expired - Lifetime
- 1986-03-25 AT AT86902217T patent/ATE87977T1/de not_active IP Right Cessation
- 1986-03-25 JP JP61501992A patent/JPH0691832B2/ja not_active Expired - Lifetime
- 1986-03-25 EP EP86902217A patent/EP0215110B1/de not_active Expired - Lifetime
- 1986-03-25 AU AU56657/86A patent/AU594950B2/en not_active Expired
- 1986-03-25 WO PCT/US1986/000579 patent/WO1986005810A1/en not_active Ceased
- 1986-03-25 ZA ZA862240A patent/ZA862240B/xx unknown
- 1986-03-26 IL IL78278A patent/IL78278A0/xx unknown
- 1986-03-26 CN CN86102889A patent/CN1034588C/zh not_active Expired - Lifetime
- 1986-11-25 NO NO864724A patent/NO302709B1/no unknown
- 1986-11-26 DK DK198605698A patent/DK175223B1/da not_active IP Right Cessation
1994
- 1994-05-09 JP JP6117443A patent/JP2602628B2/ja not_active Expired - Lifetime
- 1994-05-09 JP JP6117435A patent/JPH07102152B2/ja not_active Expired - Lifetime
- 1994-05-09 JP JP6117430A patent/JP2568383B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
CN86102889A (zh)	1986-11-26
JPH07102152B2 (ja)	1995-11-08
DK569886A (da)	1986-11-26
EP0215110A1 (de)	1987-03-25
JPH07143885A (ja)	1995-06-06
JPH07145200A (ja)	1995-06-06
DE3688225T2 (de)	1993-07-22
CA1339305C (en)	1997-08-19
AU594950B2 (en)	1990-03-22
DE3688225D1 (de)	1993-05-13
GB8507833D0 (en)	1985-05-01
NO864724L (no)	1987-01-23
JPS62502305A (ja)	1987-09-10
WO1986005810A1 (en)	1986-10-09
JPH0691832B2 (ja)	1994-11-16
DK175223B1 (da)	2004-07-12
JPH07143896A (ja)	1995-06-06
ATE87977T1 (de)	1993-04-15
JP2602628B2 (ja)	1997-04-23
JP2568383B2 (ja)	1997-01-08
EP0215110A4 (de)	1987-07-09
AU5665786A (en)	1986-10-23
DK569886D0 (da)	1986-11-26
CN1034588C (zh)	1997-04-16
ES553374A0 (es)	1987-05-16
EP0215110B1 (de)	1993-04-07
ES8705921A1 (es)	1987-05-16
ZA862240B (en)	1986-11-26
IL78278A0 (en)	1986-07-31

Publication	Publication Date	Title
US4693973A (en)	1987-09-15	DNA sequences, recombinant DNA molecules and processes for producing bovine growth hormone-like polypeptides in high yield
Seeburg et al.	1983	Efficient bacterial expression of bovine and porcine growth hormones
DK172210B1 (da)	1998-01-05	Hirudinderivater
JP2533470B2 (ja)	1996-09-11	豚成長ホルモンを生産するためのｄｎａ配列，組換ｄｎａ分子および生産方法
HUT64582A (en)	1994-01-28	Method for producing recombinant human interleukin-1 inhibitor
EP0460709B1 (de)	1997-05-21	AraB-Promoter und Verfahren zur Herstellung von Polypeptiden einschliesslich Cecropinen mittels mikrobiologischer Verfahren
NO813248L (no)	1982-03-26	Fremstilling av human-fibroblast-interferon.
US5705484A (en)	1998-01-06	Biologically active polypeptide fusion dimers
HU202584B (en)	1991-03-28	Process for producing gn-csf-proteine derivatives and pharmaceutical compositions containing them
EP0542679A1 (de)	1993-05-19	Neue Hybride von den transformierenden Wachstumsfaktoren
NO174717B (no)	1994-03-14	Fremgangsmaate for fremstilling av et fiskeveksthormon-polypeptid fra Oncorhynchus keta samt ekspresjonsvektorer til bruk ved fremgangsmaaten
WO1993003152A1 (en)	1993-02-18	Igf-ii analogues
NO302709B1 (no)	1998-04-14	Fremgangsmåte ved forbedret produksjon av et polypeptid i en vertscelle
EP0070675A1 (de)	1983-01-26	Strukturiertes Gen für die Polyprotein-vorstufe des menschlichen Calcitonins
US5654177A (en)	1997-08-05	Production of human somatomedin C
EP0483509B1 (de)	1995-07-19	Synthetisches Gen für menschliches Parathyroidhormon
NZ231443A (en)	1992-03-26	Improved production of a specific polypeptide in a transformed host
EP0423641A2 (de)	1991-04-24	Expressionsvektor, transformierter Mikroorganismus, Fusionsprotein und Verfahren zur Herstellung von Plättchen Faktor 4 oder TgF-alpha
Wang et al.	2005	High-level expression of human TFF3 in Escherichia coli
HU196458B (en)	1988-11-28	Process for enhancing protein expression by means of the modification of the dna sequence of the trp-operone between the shine-dalgarno sequence and the start codone