ZA862240B - Production of human somatomedin c - Google Patents

Production of human somatomedin c

Info

Publication number
ZA862240B
ZA862240B ZA862240A ZA862240A ZA862240B ZA 862240 B ZA862240 B ZA 862240B ZA 862240 A ZA862240 A ZA 862240A ZA 862240 A ZA862240 A ZA 862240A ZA 862240 B ZA862240 B ZA 862240B
Authority
ZA
South Africa
Prior art keywords
production
dna sequences
human
optimal
somatomedin
Prior art date
Application number
ZA862240A
Other languages
English (en)
Inventor
Gary N Buell
Nageswararao Movva
Original Assignee
Biogen Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Nv filed Critical Biogen Nv
Publication of ZA862240B publication Critical patent/ZA862240B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Compounds Of Unknown Constitution (AREA)
ZA862240A 1985-03-26 1986-03-25 Production of human somatomedin c ZA862240B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858507833A GB8507833D0 (en) 1985-03-26 1985-03-26 Production of human somatomedin c

Publications (1)

Publication Number Publication Date
ZA862240B true ZA862240B (en) 1986-11-26

Family

ID=10576658

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA862240A ZA862240B (en) 1985-03-26 1986-03-25 Production of human somatomedin c

Country Status (14)

Country Link
EP (1) EP0215110B1 (de)
JP (4) JPH0691832B2 (de)
CN (1) CN1034588C (de)
AT (1) ATE87977T1 (de)
AU (1) AU594950B2 (de)
CA (1) CA1339305C (de)
DE (1) DE3688225T2 (de)
DK (1) DK175223B1 (de)
ES (1) ES8705921A1 (de)
GB (1) GB8507833D0 (de)
IL (1) IL78278A0 (de)
NO (1) NO302709B1 (de)
WO (1) WO1986005810A1 (de)
ZA (1) ZA862240B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ221789A (en) * 1986-09-12 1991-05-28 Genentech Inc Recombinant prorelaxin, its preparation and pharmaceutical compositions comprising it
GB8712540D0 (en) * 1987-05-28 1987-07-01 Ucb Sa Expression of human proapolipoprotein a-i
US4876242A (en) * 1987-09-21 1989-10-24 Merck & Co., Inc. Human insulin-like growth factor analoges with reduced binding to serum carrier proteins and their production in yeast
AUPP807899A0 (en) 1999-01-08 1999-02-04 University Of Queensland, The Codon utilization
JP6018719B1 (ja) * 2016-03-15 2016-11-02 Ｂｘ新生精機株式会社 シャッター開閉機の巻上装置

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3486491T2 (de) * 1983-04-25 2003-01-16 Chiron Corp., Emeryville Hybrid-DNS-Synthesis von reifen insulinähnlichen Wachstumsfaktoren
IL71991A (en) * 1983-06-06 1994-05-30 Genentech Inc Preparation of human FGI and FGE in their processed form through recombinant AND tranology in prokaryotes
SE8303626D0 (sv) * 1983-06-23 1983-06-23 Kabigen Ab A recombinant plasmid a transformant microorganism, a polydoxyrebonucleotide segment, a process for producing a biologically active protein, and the protein thus produced
EP0151760A1 (de) * 1984-01-06 1985-08-21 Takeda Chemical Industries, Ltd. DNA und ihre Verwendung
US4758512A (en) * 1984-03-06 1988-07-19 President And Fellows Of Harvard College Hosts and methods for producing recombinant products in high yields

Also Published As

Publication number Publication date
CN86102889A (zh) 1986-11-26
JPH07102152B2 (ja) 1995-11-08
DK569886A (da) 1986-11-26
EP0215110A1 (de) 1987-03-25
JPH07143885A (ja) 1995-06-06
JPH07145200A (ja) 1995-06-06
DE3688225T2 (de) 1993-07-22
CA1339305C (en) 1997-08-19
AU594950B2 (en) 1990-03-22
DE3688225D1 (de) 1993-05-13
GB8507833D0 (en) 1985-05-01
NO864724L (no) 1987-01-23
JPS62502305A (ja) 1987-09-10
WO1986005810A1 (en) 1986-10-09
JPH0691832B2 (ja) 1994-11-16
DK175223B1 (da) 2004-07-12
JPH07143896A (ja) 1995-06-06
NO302709B1 (no) 1998-04-14
ATE87977T1 (de) 1993-04-15
JP2602628B2 (ja) 1997-04-23
JP2568383B2 (ja) 1997-01-08
EP0215110A4 (de) 1987-07-09
AU5665786A (en) 1986-10-23
DK569886D0 (da) 1986-11-26
CN1034588C (zh) 1997-04-16
ES553374A0 (es) 1987-05-16
EP0215110B1 (de) 1993-04-07
ES8705921A1 (es) 1987-05-16
IL78278A0 (en) 1986-07-31

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