NO305433B1 - Syklopropylderivat samt anvendelse av dette - Google Patents

Syklopropylderivat samt anvendelse av dette

Info

Publication number
NO305433B1
NO305433B1 NO952633A NO952633A NO305433B1 NO 305433 B1 NO305433 B1 NO 305433B1 NO 952633 A NO952633 A NO 952633A NO 952633 A NO952633 A NO 952633A NO 305433 B1 NO305433 B1 NO 305433B1
Authority
NO
Norway
Prior art keywords
cyclopropyl
dibromohexanoyl
give
formula
agents
Prior art date
Application number
NO952633A
Other languages
English (en)
Norwegian (no)
Other versions
NO952633L (no
NO952633D0 (no
Inventor
Maria-Josu Verde Casanova
Alvaro Galiano Ramsos
Original Assignee
Inst Investigacion Desarrollo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Investigacion Desarrollo filed Critical Inst Investigacion Desarrollo
Publication of NO952633D0 publication Critical patent/NO952633D0/no
Publication of NO952633L publication Critical patent/NO952633L/no
Publication of NO305433B1 publication Critical patent/NO305433B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Anesthesiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO952633A 1993-11-04 1995-07-03 Syklopropylderivat samt anvendelse av dette NO305433B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES09302303A ES2082703B1 (es) 1993-11-04 1993-11-04 Nuevos derivados de ciclopropilo, procedimientos para su preparacion y aplicaciones.
PCT/ES1994/000107 WO1995012576A1 (es) 1993-11-04 1994-11-03 Nuevos derivados de ciclopropilo, procedimientos para su preparacion y aplicaciones

Publications (3)

Publication Number Publication Date
NO952633D0 NO952633D0 (no) 1995-07-03
NO952633L NO952633L (no) 1995-09-01
NO305433B1 true NO305433B1 (no) 1999-05-31

Family

ID=8283511

Family Applications (1)

Application Number Title Priority Date Filing Date
NO952633A NO305433B1 (no) 1993-11-04 1995-07-03 Syklopropylderivat samt anvendelse av dette

Country Status (17)

Country Link
EP (1) EP0677514B1 (de)
JP (1) JP2931103B2 (de)
KR (1) KR100201346B1 (de)
AT (1) ATE188211T1 (de)
AU (1) AU693123B2 (de)
CA (1) CA2153264C (de)
DE (1) DE69422386T2 (de)
DK (1) DK0677514T3 (de)
ES (1) ES2082703B1 (de)
FI (1) FI953290A7 (de)
GR (1) GR3032976T3 (de)
HU (1) HU217550B (de)
NO (1) NO305433B1 (de)
NZ (1) NZ275120A (de)
PT (1) PT677514E (de)
RU (1) RU2125045C1 (de)
WO (1) WO1995012576A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5986141A (en) * 1998-09-29 1999-11-16 Eastman Chemical Company Process for the production of cyclopropanemethylamine
RU2504538C2 (ru) * 2012-04-17 2014-01-20 Государственное бюджетное образовательное учреждение высшего профессионального образования "Пермская государственная фармацевтическая академия" Министерства здравоохранения и социального развития Российской Федерации (ГБОУ ВПО ПГФА Минздравсоцразвития России) 2,6-диметиланилид n-циклогексилпирролидин-2-карбоновой кислоты гидрохлорид, проявляющий активность при поверхностной, инфильтрационной и проводниковой анестезии
CN106699744B (zh) * 2015-11-18 2021-05-11 四川海思科制药有限公司 一种杂环类酰胺衍生物及其制备方法和在药学上的应用
CN108218846A (zh) * 2016-12-22 2018-06-29 四川海思科制药有限公司 噻吩衍生物的新固态形式及其制备方法和用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB775749A (en) * 1955-04-06 1957-05-29 Bofors Ab Method of preparing amides of n-alkyl piperidine monocarboxylic acid and n-alkyl pyrrolidine -a-monocarboxylic acid
GB869978A (en) * 1958-03-13 1961-06-07 Bofors Ab Method of producing n-alkyl-and-cycloalkyl-piperidine carboxylic acid amides
GB889225A (de) * 1959-07-01
SE7607114L (sv) * 1976-06-22 1977-12-23 Bofors Ab Sett att framstella hydrokloriden av n-metylpiperidin-2-karbonsyra-2,6-xyllidid
AU560367B2 (en) * 1983-08-01 1987-04-02 Astra Lakemedel Aktiebolag L-n-n-propylpipecolic acid-2,6-xylidide and method for preparing the same
US4695576A (en) * 1984-07-09 1987-09-22 Astra Lake Medel Aktiebolag L-N-n-propylpipecolic acid-2,6-xylidide
SE451840B (sv) * 1986-01-03 1987-11-02 Astra Laekemedel Ab Optiskt rent monohydrat av s-(-)-1-propyl-2',6'-pipekoloxylididhydroklorid, sett att framstella denna och farmaceutiska beredningar for lokalbedovning
SU1579455A3 (ru) * 1987-07-01 1990-07-15 Астра Лекемедель Актиеболаг (Фирма) Способ получени оптически чистого моногидрата S-(-)-1-пропил-2 @ ,6 @ -пипеколоксилидид гидрохлорида

Also Published As

Publication number Publication date
JPH08508044A (ja) 1996-08-27
AU693123B2 (en) 1998-06-25
CA2153264A1 (en) 1995-05-11
ES2082703A1 (es) 1996-03-16
DE69422386D1 (de) 2000-02-03
HUT72899A (en) 1996-06-28
KR960700232A (ko) 1996-01-19
PT677514E (pt) 2000-06-30
JP2931103B2 (ja) 1999-08-09
WO1995012576A1 (es) 1995-05-11
RU95115550A (ru) 1997-06-10
ATE188211T1 (de) 2000-01-15
FI953290L (fi) 1995-08-25
HU217550B (hu) 2000-02-28
EP0677514B1 (de) 1999-12-29
DK0677514T3 (da) 2000-06-13
ES2082703B1 (es) 1996-12-16
HU9502005D0 (en) 1995-09-28
NZ275120A (en) 1999-09-29
GR3032976T3 (en) 2000-07-31
RU2125045C1 (ru) 1999-01-20
FI953290A0 (fi) 1995-07-03
DE69422386T2 (de) 2000-07-27
NO952633L (no) 1995-09-01
CA2153264C (en) 1999-09-14
KR100201346B1 (ko) 1999-06-15
AU8062094A (en) 1995-05-23
EP0677514A1 (de) 1995-10-18
NO952633D0 (no) 1995-07-03
FI953290A7 (fi) 1995-08-25

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Legal Events

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MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN MAY 2002