NO305594B1 - FremgangsmÕte for fremstilling av chirale nitriler - Google Patents

FremgangsmÕte for fremstilling av chirale nitriler

Info

Publication number: NO305594B1
Authority: NO; Norway
Prior art keywords: preparation; cir; give; preparing; single enantiomer
Prior art date: 1993-09-27

Application number

NO961224A

Other languages

English (en)

Norwegian (no)

Other versions

NO961224L (no

NO961224D0 (no

Inventor

Raymond Mccague

Shouming Wang

Original Assignee

Chiroscience Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-09-27

Filing date

1996-03-26

Publication date

1999-06-28

1996-03-26 Application filed by Chiroscience Ltd filed Critical Chiroscience Ltd

1996-03-26 Publication of NO961224L publication Critical patent/NO961224L/no

1996-03-26 Publication of NO961224D0 publication Critical patent/NO961224D0/no

1999-06-28 Publication of NO305594B1 publication Critical patent/NO305594B1/no

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
- C07C255/42—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being further bound to other hetero atoms
- C07C255/43—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being further bound to other hetero atoms the carbon skeleton being further substituted by singly-bound oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/32—Separation; Purification; Stabilisation; Use of additives
- C07C253/34—Separation; Purification

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

NO961224A 1993-09-27 1996-03-26 FremgangsmÕte for fremstilling av chirale nitriler NO305594B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB939319918A GB9319918D0 (en)	1993-09-27	1993-09-27	Chiral compounds and their preparation
PCT/GB1994/002091 WO1995009150A1 (fr)	1993-09-27	1994-09-26	Nitriles chiraux, leur preparation et leur utilisation dans la fabrication de verapamil et de ses analogues

Publications (3)

Publication Number	Publication Date
NO961224L NO961224L (no)	1996-03-26
NO961224D0 NO961224D0 (no)	1996-03-26
NO305594B1 true NO305594B1 (no)	1999-06-28

Family

ID=10742593

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO961224A NO305594B1 (no)	1993-09-27	1996-03-26	FremgangsmÕte for fremstilling av chirale nitriler

Country Status (12)

Country	Link
EP (1)	EP0721448B1 (fr)
JP (1)	JPH09502995A (fr)
CN (1)	CN1038838C (fr)
AT (1)	ATE163920T1 (fr)
AU (1)	AU676773B2 (fr)
CA (1)	CA2171431A1 (fr)
DE (1)	DE69409001T2 (fr)
ES (1)	ES2113126T3 (fr)
FI (1)	FI961356A7 (fr)
GB (1)	GB9319918D0 (fr)
NO (1)	NO305594B1 (fr)
WO (1)	WO1995009150A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19502967A1 (de) *	1995-01-31	1996-08-01	Basf Ag	Verfahren zur Racemattrennung von 2-Aryl-2-omega-alkylaminoalkannitrilen
US5892093A (en) *	1996-02-08	1999-04-06	Darwin Discovery Limited	Resolution
AU705865B2 (en) *	1996-02-08	1999-06-03	Darwin Discovery Limited	Resolution of 4-cyano-4-(3,4-dimethoxyphenyl) -5-methylhexanoic acid
GB9616549D0 (en) *	1996-08-06	1996-09-25	Chiroscience Ltd	Therapeutic product and its use
GB9616504D0 (en) *	1996-08-06	1996-09-25	Chiroscience Ltd	Therapeutic product and its use
AU3778497A (en) *	1996-08-06	1998-02-25	Darwin Discovery Limited	Therapeutic utilities of verapamil enantiomers
ITMI20071160A1 (it) *	2007-06-07	2008-12-08	Cosma S P A	Procedimento di risoluzione del verapamil

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2059923C3 (de) *	1970-12-05	1979-01-25	Knoll Ag, 6700 Ludwigshafen	l-a-Isopropyl-o-[(N-methyl-N-homoveratryl)v-aminopropyl] -3,4-dimethoxyphenylacetonitril, Verfahren zu dessen Herstellung und dieses enthaltende Arzneimittel
DE3603032A1 (de) *	1986-01-31	1987-08-06	Basf Ag	Basisch substituierte phenylacetonitrile, ihre herstellung und diese enthaltende arzneimittel
PT96284A (pt) *	1989-12-21	1991-09-30	Searle & Co	Processo para a preparacao de derivados de omega-amino-alfa-fenilalcanonitrilo
DE4203547A1 (de) *	1992-02-07	1993-08-12	Knoll Ag	Verfahren zur racemattrennung von verapamil

1993
- 1993-09-27 GB GB939319918A patent/GB9319918D0/en active Pending
1994
- 1994-09-26 EP EP94927719A patent/EP0721448B1/fr not_active Expired - Lifetime
- 1994-09-26 FI FI961356A patent/FI961356A7/fi unknown
- 1994-09-26 WO PCT/GB1994/002091 patent/WO1995009150A1/fr not_active Ceased
- 1994-09-26 JP JP7510174A patent/JPH09502995A/ja active Pending
- 1994-09-26 DE DE69409001T patent/DE69409001T2/de not_active Expired - Fee Related
- 1994-09-26 CA CA002171431A patent/CA2171431A1/fr not_active Abandoned
- 1994-09-26 CN CN94193530A patent/CN1038838C/zh not_active Expired - Fee Related
- 1994-09-26 AT AT94927719T patent/ATE163920T1/de not_active IP Right Cessation
- 1994-09-26 ES ES94927719T patent/ES2113126T3/es not_active Expired - Lifetime
- 1994-09-26 AU AU77025/94A patent/AU676773B2/en not_active Ceased
1996
- 1996-03-26 NO NO961224A patent/NO305594B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
HK1007657A1 (en)	1999-04-16
WO1995009150A1 (fr)	1995-04-06
JPH09502995A (ja)	1997-03-25
GB9319918D0 (en)	1993-11-10
ATE163920T1 (de)	1998-03-15
FI961356A0 (fi)	1996-03-25
EP0721448A1 (fr)	1996-07-17
DE69409001D1 (de)	1998-04-16
ES2113126T3 (es)	1998-04-16
FI961356L (fi)	1996-03-25
NO961224L (no)	1996-03-26
CA2171431A1 (fr)	1995-04-06
AU676773B2 (en)	1997-03-20
EP0721448B1 (fr)	1998-03-11
AU7702594A (en)	1995-04-18
DE69409001T2 (de)	1998-07-02
CN1131941A (zh)	1996-09-25
FI961356A7 (fi)	1996-03-25
CN1038838C (zh)	1998-06-24
NO961224D0 (no)	1996-03-26

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Legal Events

Date	Code	Title	Description
2002-05-13	MM1K	Lapsed by not paying the annual fees	Free format text: LAPSED IN MARCH 2002