NO307054B1 - Penam-derivater - Google Patents

Penam-derivater

Info

Publication number
NO307054B1
NO307054B1 NO943104A NO943104A NO307054B1 NO 307054 B1 NO307054 B1 NO 307054B1 NO 943104 A NO943104 A NO 943104A NO 943104 A NO943104 A NO 943104A NO 307054 B1 NO307054 B1 NO 307054B1
Authority
NO
Norway
Prior art keywords
lower alkyl
hydrogen
beta
compounds
membered heteroaromatic
Prior art date
Application number
NO943104A
Other languages
English (en)
Norwegian (no)
Other versions
NO943104L (no
NO943104D0 (no
Inventor
Christian Hubschwerlen
Jean-Luc Specklin
Hans Richter
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO943104D0 publication Critical patent/NO943104D0/no
Publication of NO943104L publication Critical patent/NO943104L/no
Publication of NO307054B1 publication Critical patent/NO307054B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/86—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with only atoms other than nitrogen atoms directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
NO943104A 1993-08-24 1994-08-23 Penam-derivater NO307054B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH251193 1993-08-24
CH168794 1994-05-31

Publications (3)

Publication Number Publication Date
NO943104D0 NO943104D0 (no) 1994-08-23
NO943104L NO943104L (no) 1995-02-27
NO307054B1 true NO307054B1 (no) 2000-01-31

Family

ID=25688383

Family Applications (1)

Application Number Title Priority Date Filing Date
NO943104A NO307054B1 (no) 1993-08-24 1994-08-23 Penam-derivater

Country Status (22)

Country Link
US (2) US5637579A (fr)
EP (1) EP0640607B1 (fr)
JP (1) JP2642314B2 (fr)
KR (1) KR100362294B1 (fr)
CN (1) CN1067078C (fr)
AT (1) ATE148705T1 (fr)
AU (1) AU674768B2 (fr)
CA (1) CA2129564C (fr)
CZ (1) CZ203994A3 (fr)
DE (1) DE59401750D1 (fr)
DK (1) DK0640607T3 (fr)
ES (1) ES2097589T3 (fr)
FI (1) FI113775B (fr)
GR (1) GR3023228T3 (fr)
HU (1) HUT67880A (fr)
IL (1) IL110711A (fr)
NO (1) NO307054B1 (fr)
NZ (1) NZ264272A (fr)
RU (1) RU2139290C1 (fr)
SG (1) SG48064A1 (fr)
TW (1) TW383308B (fr)
UA (1) UA29435C2 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5686441A (en) * 1995-08-04 1997-11-11 Syphar Laboratories, Inc. Penam sulfones as β-lactamase inhibitors
US6150350A (en) * 1997-09-15 2000-11-21 Hoffman-La Roche Inc. Antimicrobial compositions
WO1999033838A1 (fr) 1997-12-29 1999-07-08 Research Corporation Technologies, Inc. DERIVES D'ACIDE PENICILLANIQUE 2β-SUBSTITUE-6-ALKYLIDENE UTILISES COMME INHIBITEURS DE LA BETA-LACTAMASE
WO2000012048A2 (fr) * 1998-09-01 2000-03-09 Merck & Co., Inc. Compositions antibacteriennes carbapenems et methodes de traitement associees
US6395726B1 (en) 1999-01-26 2002-05-28 American Cyanamid Company 3,6-disubstituted penam sulfone derivatives
WO2000043399A1 (fr) * 1999-01-26 2000-07-27 American Cyanamid Company Derives de pename sulfone 3,6-disubstitues comme antibacteriens
US6407091B1 (en) 1999-04-15 2002-06-18 Research Corporation Technologies, Inc. β-lactamase inhibiting compounds
US6221859B1 (en) 1999-08-27 2001-04-24 Merck & Co., Inc. Carbapenem antibacterial compositions and methods of the treatment
AU2001292732A1 (en) * 2000-09-12 2002-03-26 Larry C. Blasczcak Beta-lactam analogs and uses therefor
CN1479906A (zh) * 2000-10-11 2004-03-03 用于健康护理数据的通信的系统
WO2003020732A2 (fr) 2001-07-24 2003-03-13 Alamx, L.L.C. 7-alkylidene-3-substitues-3-cephem-4-carboxylates utilises en tant qu'inhibiteurs de $g(b)-lactamase
AU2003224874A1 (en) 2002-04-04 2003-10-27 Alamx, L.L.C. INHIBITORS OF SERINE AND METALLO-ss-LACTAMASES
WO2007065288A2 (fr) * 2005-12-07 2007-06-14 Basilea Pharmaceutica Ag Associations utiles d'antibiotiques monobactames et d'inhibiteurs de la beta-lactamase
AU2012233003B2 (en) * 2005-12-07 2014-12-18 Basilea Pharmaceutica Ag Useful combinations of monobactam antibiotics with beta-lactamase inhibitors
US11083706B2 (en) 2016-07-21 2021-08-10 Conopco, Inc. Lactams for use in the treatment of skin lesions
US11160787B2 (en) 2016-07-21 2021-11-02 Conopco, Inc. 4-(4-chlorophenyl)-5-methylene-pyrrol-2-one and 5-methylene-4-(p-tolyl)pyrrol-2-one for use in the treatment of gram negative bacterial infections
US10875830B2 (en) 2016-07-21 2020-12-29 Conopeo, Inc. Method of treatment
US12329747B2 (en) 2019-01-22 2025-06-17 Board of Regents of the Nevada System of Higher Education on behalf of Nevada State College Use of lipophilic beta-lactam antibiotics and carboxylate esters for the treatment of bacterial infections within citrus and other plant species

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT365594B (de) * 1978-11-24 1982-01-25 Erba Farmitalia Verfahren zur herstellung von neuen 7-oxo-4-thia1-aza-bicyclo-(3,2,0)heptanderivaten
US4282236A (en) * 1979-11-07 1981-08-04 Beecham Group Limited β-Lactam antibacterial agents, their use in pharmaceutical compositions, and intermediates
US4365174A (en) * 1980-07-31 1982-12-21 Rca Corporation Pulse counter type circuit for power-up indication
ZA826687B (en) * 1981-09-14 1983-07-27 Pfizer Beta-lactamase inhibiting 2-beta-substituted-2-alpha-methyl 5(r)penam-3-alpha-carboxylic acid 1,1-dioxides and intermediates therefor
GB8509180D0 (en) * 1985-04-10 1985-05-15 Erba Farmitalia Penem derivatives
US4861768A (en) * 1986-02-27 1989-08-29 Taiho Pharmaceutical Company, Limited 2 β-substituted thiomethylpenicillin derivatives and their preparation and use
US4891369A (en) * 1986-12-03 1990-01-02 Taiho Pharmaceutical Company, Limited 2β-Substituted-methylpenicillanic acid derivatives, and salts and esters thereof
US5132300A (en) * 1989-06-01 1992-07-21 Pfizer Inc. Beta-lactam elastase inhibitors

Also Published As

Publication number Publication date
FI943885L (fi) 1995-02-25
RU94030236A (ru) 1996-06-20
CA2129564C (fr) 2006-07-25
SG48064A1 (en) 1998-04-17
FI943885A0 (fi) 1994-08-24
KR950005830A (ko) 1995-03-20
IL110711A0 (en) 1994-11-11
US5644053A (en) 1997-07-01
HU9402391D0 (en) 1994-10-28
AU674768B2 (en) 1997-01-09
JPH0782273A (ja) 1995-03-28
CN1067078C (zh) 2001-06-13
ATE148705T1 (de) 1997-02-15
TW383308B (en) 2000-03-01
JP2642314B2 (ja) 1997-08-20
AU7035694A (en) 1995-03-09
EP0640607B1 (fr) 1997-02-05
RU2139290C1 (ru) 1999-10-10
KR100362294B1 (ko) 2005-08-25
NO943104L (no) 1995-02-27
FI113775B (fi) 2004-06-15
UA29435C2 (uk) 2000-11-15
EP0640607A1 (fr) 1995-03-01
DK0640607T3 (da) 1997-06-16
NO943104D0 (no) 1994-08-23
GR3023228T3 (en) 1997-07-30
ES2097589T3 (es) 1997-04-01
HUT67880A (en) 1995-05-29
CN1106408A (zh) 1995-08-09
CA2129564A1 (fr) 1995-02-25
IL110711A (en) 1999-08-17
CZ203994A3 (en) 1995-03-15
US5637579A (en) 1997-06-10
NZ264272A (en) 1996-10-28
DE59401750D1 (de) 1997-03-20

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Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN FEBRUARY 2002