NO307692B1 - Mikrokapsler fremstilt fra biologisk nedbrytbare blandingspolymerer, fremgangsmåte til fremstilling av mikrokapslene samt kontrastmiddel - Google Patents

Mikrokapsler fremstilt fra biologisk nedbrytbare blandingspolymerer, fremgangsmåte til fremstilling av mikrokapslene samt kontrastmiddel

Info

Publication number
NO307692B1
NO307692B1 NO951138A NO951138A NO307692B1 NO 307692 B1 NO307692 B1 NO 307692B1 NO 951138 A NO951138 A NO 951138A NO 951138 A NO951138 A NO 951138A NO 307692 B1 NO307692 B1 NO 307692B1
Authority
NO
Norway
Prior art keywords
microcapsules
preparation
contrast agent
blend polymers
biodegradable blend
Prior art date
Application number
NO951138A
Other languages
English (en)
Norwegian (no)
Other versions
NO951138D0 (no
NO951138L (no
Inventor
Thomas Fritzsch
Dieter Heldmann
Werner Weitschies
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO951138D0 publication Critical patent/NO951138D0/no
Publication of NO951138L publication Critical patent/NO951138L/no
Publication of NO307692B1 publication Critical patent/NO307692B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasonic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasonic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasonic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasonic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/226—Solutes, emulsions, suspensions, dispersions, semi-solid forms, e.g. hydrogels

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Radiology & Medical Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Acoustics & Sound (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
NO951138A 1992-09-26 1995-03-24 Mikrokapsler fremstilt fra biologisk nedbrytbare blandingspolymerer, fremgangsmåte til fremstilling av mikrokapslene samt kontrastmiddel NO307692B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4232755A DE4232755A1 (de) 1992-09-26 1992-09-26 Mikropartikelpräparationen aus biologisch abbaubaren Mischpolymeren
PCT/EP1993/002422 WO1994007539A1 (fr) 1992-09-26 1993-09-08 Preparations de microparticules a base de copolymeres biodegradables

Publications (3)

Publication Number Publication Date
NO951138D0 NO951138D0 (no) 1995-03-24
NO951138L NO951138L (no) 1995-03-24
NO307692B1 true NO307692B1 (no) 2000-05-15

Family

ID=6469216

Family Applications (1)

Application Number Title Priority Date Filing Date
NO951138A NO307692B1 (no) 1992-09-26 1995-03-24 Mikrokapsler fremstilt fra biologisk nedbrytbare blandingspolymerer, fremgangsmåte til fremstilling av mikrokapslene samt kontrastmiddel

Country Status (18)

Country Link
EP (1) EP0662005B1 (fr)
JP (1) JPH08504398A (fr)
KR (1) KR100287975B1 (fr)
CN (1) CN1078815C (fr)
AT (1) ATE165517T1 (fr)
AU (1) AU687360B2 (fr)
CA (1) CA2145505C (fr)
DE (2) DE4232755A1 (fr)
DK (1) DK0662005T3 (fr)
ES (1) ES2118251T3 (fr)
FI (1) FI117124B (fr)
HU (1) HU221972B1 (fr)
IL (1) IL107108A (fr)
NO (1) NO307692B1 (fr)
NZ (1) NZ255409A (fr)
TW (1) TW394688B (fr)
WO (1) WO1994007539A1 (fr)
ZA (1) ZA937099B (fr)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020150539A1 (en) 1989-12-22 2002-10-17 Unger Evan C. Ultrasound imaging and treatment
US5922304A (en) * 1989-12-22 1999-07-13 Imarx Pharmaceutical Corp. Gaseous precursor filled microspheres as magnetic resonance imaging contrast agents
US5205290A (en) 1991-04-05 1993-04-27 Unger Evan C Low density microspheres and their use as contrast agents for computed tomography
US7083572B2 (en) 1993-11-30 2006-08-01 Bristol-Myers Squibb Medical Imaging, Inc. Therapeutic delivery systems
US6333021B1 (en) * 1994-11-22 2001-12-25 Bracco Research S.A. Microcapsules, method of making and their use
EP0727225A3 (fr) * 1995-02-14 1997-01-15 Sonus Pharma Inc Compositions et méthodes pour l'imagerie ultrasonique dirigée
DE19510690A1 (de) * 1995-03-14 1996-09-19 Schering Ag Polymere Nano- und/oder Mikropartikel, Verfahren zu deren Herstellung, sowie Verwendung in medizinischen Diagnostik und Therapie
US6521211B1 (en) 1995-06-07 2003-02-18 Bristol-Myers Squibb Medical Imaging, Inc. Methods of imaging and treatment with targeted compositions
CA2218541A1 (fr) * 1995-06-07 1996-12-19 Imarx Pharmaceutical Corp. Nouvelles compositions ciblees, destinees a une utilisation diagnostique et therapeutique
US5780010A (en) * 1995-06-08 1998-07-14 Barnes-Jewish Hospital Method of MRI using avidin-biotin conjugated emulsions as a site specific binding system
US6548046B1 (en) 1995-06-08 2003-04-15 Barnes-Jewish Hospital Site specific binding system, imaging compositions and methods
US6821506B2 (en) 1995-06-08 2004-11-23 Barnes-Jewish Hospital Site specific binding system, imaging compositions and methods
US5955143A (en) * 1995-12-21 1999-09-21 Drexel University Hollow polymer microcapsules and method of producing the same
CA2252617A1 (fr) 1996-05-01 1997-11-06 Imarx Pharmaceutical Corp. Procedes d'apport de composes dans une cellule
US5849727A (en) * 1996-06-28 1998-12-15 Board Of Regents Of The University Of Nebraska Compositions and methods for altering the biodistribution of biological agents
US5846517A (en) 1996-09-11 1998-12-08 Imarx Pharmaceutical Corp. Methods for diagnostic imaging using a renal contrast agent and a vasodilator
BR9712683A (pt) 1996-10-28 1999-10-19 Nyomed Imaging A S Agente de diagnóstico e/ou terapeuticamente ativo alvejável, formulação combinada, processo para preparação e uso do mesmo, formulação combinada, e processos para gerar imagens intensificadas de um corpo animal humano ou não-humano e para investigação in vitro de alvejamento por um agente.
US6261537B1 (en) 1996-10-28 2001-07-17 Nycomed Imaging As Diagnostic/therapeutic agents having microbubbles coupled to one or more vectors
WO1998018498A2 (fr) * 1996-10-28 1998-05-07 Marsden, John, Christopher Ameliorations apportees a des agents diagnostiques et/ou therapeutiques ou les concernant
US6331289B1 (en) 1996-10-28 2001-12-18 Nycomed Imaging As Targeted diagnostic/therapeutic agents having more than one different vectors
US6537246B1 (en) 1997-06-18 2003-03-25 Imarx Therapeutics, Inc. Oxygen delivery agents and uses for the same
US7452551B1 (en) 2000-10-30 2008-11-18 Imarx Therapeutics, Inc. Targeted compositions for diagnostic and therapeutic use
US20010003580A1 (en) 1998-01-14 2001-06-14 Poh K. Hui Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
DE19925311B4 (de) 1999-05-27 2004-06-09 Schering Ag Mehrstufen-Verfahren zur Herstellung von gasgefüllten Mikrokapseln
US7220401B2 (en) 1999-09-24 2007-05-22 Barnes-Jewish Hospital Blood clot-targeted nanoparticles
DE10013850A1 (de) * 2000-03-15 2001-09-20 Schering Ag Gasgefüllte Mikrokapseln enthaltend funktionalisiertes Polyalkylcyanacrylat, sowie Verfahren zu deren Herstellung
DE10119522A1 (de) * 2001-04-20 2002-12-05 Innovacell Biotechnologie Gmbh Herstellung und Anwendung einer Suspensionszusammensetzung mit einem Ultraschall-Kontrastmittel
US7131997B2 (en) 2002-03-29 2006-11-07 Scimed Life Systems, Inc. Tissue treatment
US7462366B2 (en) 2002-03-29 2008-12-09 Boston Scientific Scimed, Inc. Drug delivery particle
US7094369B2 (en) 2002-03-29 2006-08-22 Scimed Life Systems, Inc. Processes for manufacturing polymeric microspheres
US7053134B2 (en) 2002-04-04 2006-05-30 Scimed Life Systems, Inc. Forming a chemically cross-linked particle of a desired shape and diameter
US7449236B2 (en) 2002-08-09 2008-11-11 Boston Scientific Scimed, Inc. Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
US7842377B2 (en) 2003-08-08 2010-11-30 Boston Scientific Scimed, Inc. Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
US8012454B2 (en) 2002-08-30 2011-09-06 Boston Scientific Scimed, Inc. Embolization
US7883490B2 (en) 2002-10-23 2011-02-08 Boston Scientific Scimed, Inc. Mixing and delivery of therapeutic compositions
US7588825B2 (en) 2002-10-23 2009-09-15 Boston Scientific Scimed, Inc. Embolic compositions
US7976823B2 (en) 2003-08-29 2011-07-12 Boston Scientific Scimed, Inc. Ferromagnetic particles and methods
US7901770B2 (en) 2003-11-04 2011-03-08 Boston Scientific Scimed, Inc. Embolic compositions
US7736671B2 (en) 2004-03-02 2010-06-15 Boston Scientific Scimed, Inc. Embolization
US8173176B2 (en) 2004-03-30 2012-05-08 Boston Scientific Scimed, Inc. Embolization
US7311861B2 (en) 2004-06-01 2007-12-25 Boston Scientific Scimed, Inc. Embolization
EP1815028B1 (fr) 2004-11-03 2011-10-26 Iris Molecular Diagnostics, Inc. Microbulles utilisees dans la separation par affinite
CN103146808A (zh) 2004-11-03 2013-06-12 意力速分子诊断股份有限公司 均相分析物检测
US7858183B2 (en) 2005-03-02 2010-12-28 Boston Scientific Scimed, Inc. Particles
US7727555B2 (en) 2005-03-02 2010-06-01 Boston Scientific Scimed, Inc. Particles
US7963287B2 (en) 2005-04-28 2011-06-21 Boston Scientific Scimed, Inc. Tissue-treatment methods
US9463426B2 (en) 2005-06-24 2016-10-11 Boston Scientific Scimed, Inc. Methods and systems for coating particles
US7501179B2 (en) 2005-12-21 2009-03-10 Boston Scientific Scimed, Inc. Block copolymer particles
US7947368B2 (en) 2005-12-21 2011-05-24 Boston Scientific Scimed, Inc. Block copolymer particles
KR100845010B1 (ko) * 2007-08-29 2008-07-08 한국생명공학연구원 Ｎｉｒ／ｍｒ 이중모드 분자영상용 고분자 입자 및 그제조방법
CN101518780B (zh) * 2008-12-31 2011-09-14 广东省生态环境与土壤研究所 一种用于植物修复土壤的络合剂微胶囊及其制备方法
EP2474327A1 (fr) * 2011-01-07 2012-07-11 RWTH Aachen Microdosage d'agents de contraste ultrasoniques
EP4247537A4 (fr) * 2020-11-20 2024-10-23 Encapsys, LLC Microcapsules biodégradables à libération contrôlée

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0133132B1 (ko) * 1988-02-05 1998-04-17 쉐링 아게, 베를린 운트 베르크카멘 초음파 조영제, 이의 제법 및 이의 진단제로서의 용도
DE4004430A1 (de) * 1990-02-09 1991-08-14 Schering Ag Aus polyaldehyden aufgebaute kontrastmittel
AU636481B2 (en) * 1990-05-18 1993-04-29 Bracco International B.V. Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography
GB9106686D0 (en) * 1991-03-28 1991-05-15 Hafslund Nycomed As Improvements in or relating to contrast agents

Also Published As

Publication number Publication date
WO1994007539A1 (fr) 1994-04-14
EP0662005A1 (fr) 1995-07-12
JPH08504398A (ja) 1996-05-14
HUT71683A (en) 1996-01-29
HU221972B1 (hu) 2003-03-28
DK0662005T3 (da) 1999-02-22
DE59308479D1 (de) 1998-06-04
KR950703367A (ko) 1995-09-20
ES2118251T3 (es) 1998-09-16
CN1078815C (zh) 2002-02-06
IL107108A (en) 1998-01-04
KR100287975B1 (ko) 2001-05-02
NO951138D0 (no) 1995-03-24
TW394688B (en) 2000-06-21
ATE165517T1 (de) 1998-05-15
FI951379A0 (fi) 1995-03-23
AU4959293A (en) 1994-04-26
AU687360B2 (en) 1998-02-26
ZA937099B (en) 1995-03-24
EP0662005B1 (fr) 1998-04-29
HU9500876D0 (en) 1995-05-29
CA2145505C (fr) 2004-02-17
IL107108A0 (en) 1993-12-28
FI117124B (fi) 2006-06-30
NO951138L (no) 1995-03-24
CA2145505A1 (fr) 1994-04-14
CN1089508A (zh) 1994-07-20
DE4232755A1 (de) 1994-03-31
FI951379L (fi) 1995-03-23
NZ255409A (en) 1997-02-24

Similar Documents

Publication Publication Date Title
FI951379A0 (fi) Biohajoavista kopolymeereistä koostuvia mikrohiukkasvalmisteita
CA2041260A1 (fr) Agents de contraste ultrasonore, leur procede de preparation et leur utilisation en tant qu'agents de diagnostic et de traitement
IE940809L (en) Ultrasonic contrast agents, process for their preparation¹and their use as diagnostic and therapeutic agents
NO20002788D0 (no) Nye forbindelser
CA2212058A1 (fr) Preparation et utilisation d'un ligand specifique du recepteur gaba-a.alpha.5 destine au traitement de la maladie d'alzheimer
NO911260L (no) Utleveringssystem for aromastoff og soetningsmiddel, samt fremgangsmaate for fremstilling av et slikt system.
DK0644777T3 (da) Mikropartikler, fremgangsmåde til fremstilling deraf og anvendelse deraf til dianostiske formål
MX9704030A (es) 1,1-dioxidos de 2-heterocicliloxi y tiometil-1,2,5-tiadiazolidin-3-ona y composiciones y metodo de uso de los mismos.
EP0771788A3 (fr) Sulfonimidamides substitués, procédé pour leur préparation, leur utilisation comme médicament ou agent diagnostique, ainsi que médicament les contenant
ATE510552T1 (de) Verfahren zur herstellung von sekretierte verkurzte varianten des humanen thyrotropinrezeptors
ITRM930291A0 (it) Procedimento per la preparazione di biopolimeri iodurati con attivita'disinfettante e cicatrizzante, e biopolimeri iodurati cosi' ottenuti.
TR199600612A2 (tr) Ikame edilmis sinamikasitguanidid'leri bunlarin imal edilmesine mahsus usul, bunlarin ilac ya da diyagnoz maddesi olarak kullanilmalari ve ayrica bunlari ihtiva eden ilaclar.
GR3035126T3 (en) Substituted 2-naphtoylguanidines, process for their preparation, their use as medicament or diagnostic agent and medicament containing them
GB9515279D0 (en) Improved therapeutic agents
TR199600753A1 (tr) Ikame edilmis benzoilguanidin'leri, bunlarin imal edilmesine mahsus usul, bunlarin ilac ya da diyagnoz maddesi olarak kullanilmalari ve ayrica bunlari ihtiva eden ilaclar.
TR199600588A2 (tr) 4-Floralkil ikame edilmis benzoilguanidin'ler, bunlarin imal edilmesine mahsus usul, bunlarin ilac ya da diyagnoz maddesi olarak kullanilmalari ve bunlari ihtiva eden ilaclar.
NO911543D0 (no) Katalysatorsystem og fremgangsmaate for fremstilling av 1,2-diklorethan.
TR199600892A2 (tr) Sülfonilamino ikameli benzoilguanidin'leri, bunlarin imal edilmesine mahsus usul, bunlarin ilac ya da diyagnoz maddesi olarak kullanilmalari ve ayrica bunlari ihtiva eden ilaclar.
TR199700059A2 (tr) Ikame edilmis diarildikarbonasit-diguanidid'leri, bunlarin imal edilmesine mahsus usul, bunlarin ilac ya da diyagnoz maddesi olarak kullanilmalari ve ayrica bunlari ihtiva eden ilaclar.
NZ505085A (en) Pharmaceutical compositions comprising bipapcitide monocarboxylate and/or bipapcitide dicarboxylate for imaging and treating thrombi
IT1229693B (it) Procedimento per rendere profumate tappezzerie viniliche e prodotti cosi' ottenuti.
AU3651595A (en) Drug for the prevention and treatment of auto-immune and viral diseases, and diagnostic agents for detecting said diseases