NO308604B1 - Nye benzodioksanforbindelser - Google Patents
Nye benzodioksanforbindelserInfo
- Publication number
- NO308604B1 NO308604B1 NO950712A NO950712A NO308604B1 NO 308604 B1 NO308604 B1 NO 308604B1 NO 950712 A NO950712 A NO 950712A NO 950712 A NO950712 A NO 950712A NO 308604 B1 NO308604 B1 NO 308604B1
- Authority
- NO
- Norway
- Prior art keywords
- substd
- opt
- phenyl
- alkyl
- new
- Prior art date
Links
- BNBQRQQYDMDJAH-UHFFFAOYSA-N benzodioxan Chemical class C1=CC=C2OCCOC2=C1 BNBQRQQYDMDJAH-UHFFFAOYSA-N 0.000 title 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- -1 benzoylmethyl Chemical group 0.000 abstract 3
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000043 benzamido group Chemical group [H]N([*])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 1
- LYKMMUBOEFYJQG-UHFFFAOYSA-N piperoxan Chemical compound C1OC2=CC=CC=C2OC1CN1CCCCC1 LYKMMUBOEFYJQG-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000004953 trihalomethyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9402161A FR2716680B1 (fr) | 1994-02-25 | 1994-02-25 | Nouveaux dérivés de benzodioxane, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO950712D0 NO950712D0 (no) | 1995-02-24 |
| NO950712L NO950712L (no) | 1995-08-28 |
| NO308604B1 true NO308604B1 (no) | 2000-10-02 |
Family
ID=9460423
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO950712A NO308604B1 (no) | 1994-02-25 | 1995-02-24 | Nye benzodioksanforbindelser |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5500443A (da) |
| EP (1) | EP0669331B1 (da) |
| JP (1) | JP2959987B2 (da) |
| CN (1) | CN1064964C (da) |
| AT (1) | ATE196904T1 (da) |
| AU (1) | AU681740B2 (da) |
| CA (1) | CA2143252C (da) |
| DE (1) | DE69519047T2 (da) |
| DK (1) | DK0669331T3 (da) |
| ES (1) | ES2153019T3 (da) |
| FI (1) | FI950817A7 (da) |
| FR (1) | FR2716680B1 (da) |
| GR (1) | GR3035082T3 (da) |
| NO (1) | NO308604B1 (da) |
| NZ (1) | NZ270565A (da) |
| PT (1) | PT669331E (da) |
| ZA (1) | ZA951576B (da) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2735129B1 (fr) * | 1995-06-07 | 1997-07-11 | Adir | Nouveaux derives de l'indole, de l'indazole et du benzisoxazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2762598A1 (fr) * | 1997-04-25 | 1998-10-30 | Adir | Nouveaux composes heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennnent |
| FR2763335B1 (fr) * | 1997-05-16 | 2000-11-24 | Adir | Nouveaux composes heterocycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| HK1040055B (zh) * | 1998-05-22 | 2005-04-01 | 伊莱利利公司 | 奥氮平和氟西汀在制备治疗对抗治疗的严重抑郁症的药物中的应用 |
| US6960577B2 (en) * | 1998-05-22 | 2005-11-01 | Eli Lilly And Company | Combination therapy for treatment of refractory depression |
| GT200600159A (es) * | 2005-04-22 | 2007-03-14 | Derivados benzodioxano y benzodioxolano y usos de los mismos | |
| US20090069267A1 (en) * | 2006-01-17 | 2009-03-12 | Abrams Daniel J | Central administration of stable formulations of therapeutic agents for cns conditions |
| CL2007003044A1 (es) * | 2006-10-24 | 2008-07-04 | Wyeth Corp | Compuestos derivados de benzoxazina; composicion farmaceutica que los comprende; y uso para el tratamiento de un trastorno psicotico, bipolar, depresivo y abuso o dependencia de sustancias entre otros. |
| AU2008279636A1 (en) * | 2007-07-25 | 2009-01-29 | The Regents Of The University Of Colorado | Central administration of stable formulations of therapeutic agents for CNS conditions |
| CN102675302B (zh) * | 2011-03-17 | 2014-06-11 | 南京大学 | 含1,4-苯并二噁烷的噻二唑衍生物及其制法与其抗菌活性 |
| CN102690261B (zh) * | 2011-03-25 | 2015-02-25 | 南京大学 | 含1,4-苯并二噁烷的1,3,4-噁二唑衍生物的制法及其在抗癌药物中应用 |
| CN102746286B (zh) * | 2012-07-25 | 2015-07-15 | 山东理工大学 | 苯并二噁唑及其制备方法 |
| CN104311547A (zh) * | 2014-09-15 | 2015-01-28 | 湖南华腾制药有限公司 | 一种噻唑衍生物的制备方法 |
| CN104327065A (zh) * | 2014-09-15 | 2015-02-04 | 湖南华腾制药有限公司 | 一种n-甲基-(喹啉-4-基)甲烷胺的制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3124598A (en) * | 1962-10-02 | 1964-03-10 | Aminoalkoxy substituted benzodioxanes | |
| US3345364A (en) * | 1964-05-06 | 1967-10-03 | Janssen Pharmaceutica Nv | Benzimidazolinyl piperidines |
| FR2644786B1 (fr) * | 1989-03-21 | 1993-12-31 | Adir Cie | Nouveaux derives fluoro-4 benzoiques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
| JPH03264528A (ja) * | 1990-03-14 | 1991-11-25 | Mitsubishi Kasei Corp | 抗不安薬 |
-
1994
- 1994-02-25 FR FR9402161A patent/FR2716680B1/fr not_active Expired - Fee Related
-
1995
- 1995-02-22 US US08/392,203 patent/US5500443A/en not_active Expired - Fee Related
- 1995-02-22 FI FI950817A patent/FI950817A7/fi unknown
- 1995-02-23 DE DE69519047T patent/DE69519047T2/de not_active Expired - Fee Related
- 1995-02-23 AT AT95400382T patent/ATE196904T1/de not_active IP Right Cessation
- 1995-02-23 CA CA002143252A patent/CA2143252C/fr not_active Expired - Fee Related
- 1995-02-23 DK DK95400382T patent/DK0669331T3/da active
- 1995-02-23 PT PT95400382T patent/PT669331E/pt unknown
- 1995-02-23 AU AU13448/95A patent/AU681740B2/en not_active Ceased
- 1995-02-23 ES ES95400382T patent/ES2153019T3/es not_active Expired - Lifetime
- 1995-02-23 EP EP95400382A patent/EP0669331B1/fr not_active Expired - Lifetime
- 1995-02-24 NZ NZ270565A patent/NZ270565A/en unknown
- 1995-02-24 NO NO950712A patent/NO308604B1/no not_active IP Right Cessation
- 1995-02-24 ZA ZA951576A patent/ZA951576B/xx unknown
- 1995-02-24 CN CN951021486A patent/CN1064964C/zh not_active Expired - Fee Related
- 1995-02-24 JP JP7036808A patent/JP2959987B2/ja not_active Expired - Fee Related
-
2000
- 2000-12-15 GR GR20000402769T patent/GR3035082T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| GR3035082T3 (en) | 2001-03-30 |
| US5500443A (en) | 1996-03-19 |
| NZ270565A (en) | 1995-12-21 |
| CA2143252C (fr) | 2002-04-16 |
| FI950817A0 (fi) | 1995-02-22 |
| CN1064964C (zh) | 2001-04-25 |
| DE69519047T2 (de) | 2001-05-10 |
| EP0669331B1 (fr) | 2000-10-11 |
| AU681740B2 (en) | 1997-09-04 |
| JP2959987B2 (ja) | 1999-10-06 |
| PT669331E (pt) | 2001-01-31 |
| DK0669331T3 (da) | 2001-02-12 |
| NO950712L (no) | 1995-08-28 |
| DE69519047D1 (de) | 2000-11-16 |
| EP0669331A1 (fr) | 1995-08-30 |
| FI950817A7 (fi) | 1995-08-26 |
| ES2153019T3 (es) | 2001-02-16 |
| NO950712D0 (no) | 1995-02-24 |
| CA2143252A1 (fr) | 1995-08-26 |
| ZA951576B (en) | 1995-12-12 |
| FR2716680A1 (fr) | 1995-09-01 |
| FR2716680B1 (fr) | 1996-04-05 |
| JPH0841046A (ja) | 1996-02-13 |
| CN1120041A (zh) | 1996-04-10 |
| HK1013291A1 (en) | 1999-08-20 |
| ATE196904T1 (de) | 2000-10-15 |
| AU1344895A (en) | 1995-09-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |