NO309283B1 - Fremgangsmåte for fremstilling av et polypeptid - Google Patents

Fremgangsmåte for fremstilling av et polypeptid Download PDF

Info

Publication number
NO309283B1
NO309283B1 NO905393A NO905393A NO309283B1 NO 309283 B1 NO309283 B1 NO 309283B1 NO 905393 A NO905393 A NO 905393A NO 905393 A NO905393 A NO 905393A NO 309283 B1 NO309283 B1 NO 309283B1
Authority
NO
Norway
Prior art keywords
niger
gene
dna
promoter
sequence
Prior art date
Application number
NO905393A
Other languages
English (en)
Norwegian (no)
Other versions
NO905393L (no
NO905393D0 (no
Inventor
Leendert Hendrik De Graaff
Henriette Catharina Van Broeck
Jacob Visser
Frank Buxton
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NO905393D0 publication Critical patent/NO905393D0/no
Publication of NO905393L publication Critical patent/NO905393L/no
Publication of NO309283B1 publication Critical patent/NO309283B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • C07K14/56IFN-alpha
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01015Polygalacturonase (3.2.1.15)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Mycology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Mushroom Cultivation (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Fruits And Vegetables (AREA)
  • Peptides Or Proteins (AREA)
  • Confectionery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Selective Calling Equipment (AREA)
  • Optical Communication System (AREA)
  • Circuits Of Receivers In General (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
NO905393A 1990-01-29 1990-12-13 Fremgangsmåte for fremstilling av et polypeptid NO309283B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP90810068 1990-01-29

Publications (3)

Publication Number Publication Date
NO905393D0 NO905393D0 (no) 1990-12-13
NO905393L NO905393L (no) 1991-07-30
NO309283B1 true NO309283B1 (no) 2001-01-08

Family

ID=8205903

Family Applications (1)

Application Number Title Priority Date Filing Date
NO905393A NO309283B1 (no) 1990-01-29 1990-12-13 Fremgangsmåte for fremstilling av et polypeptid

Country Status (18)

Country Link
EP (1) EP0439997B1 (de)
JP (1) JP3329472B2 (de)
KR (1) KR0157411B1 (de)
AT (1) ATE130034T1 (de)
AU (1) AU645768B2 (de)
CA (1) CA2032035C (de)
DE (1) DE69023474T2 (de)
DK (1) DK0439997T3 (de)
ES (1) ES2079468T3 (de)
FI (1) FI103206B (de)
GR (1) GR3018044T3 (de)
HU (1) HU210989B (de)
IE (1) IE68457B1 (de)
MX (1) MX23984A (de)
NO (1) NO309283B1 (de)
NZ (1) NZ236434A (de)
PT (1) PT96310B (de)
ZA (1) ZA909987B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE1005432A4 (nl) * 1991-10-01 1993-07-20 Dsm Nv Expressiecassette voor heterologe eiwitten.
AU664223B2 (en) * 1991-12-09 1995-11-09 Unilever Plc Process for producing/secreting a protein by a transformed mould using expression/secretion regulating regions derived from an (aspergillus) endoxylanase II gene
US5858760A (en) * 1993-02-16 1999-01-12 Novo Nordisk A/S Enzyme with pectin lyase activity
US5674728A (en) * 1993-11-03 1997-10-07 Novartis Corporation Aspergillus niger vacuolar aspartyl protease
US5981227A (en) * 1995-02-09 1999-11-09 Movartis Ag Process for the production of proteins
CA2427850A1 (en) 2000-11-03 2002-05-10 Sidney Pestka Interferons, uses and compositions related thereto
DE10356218A1 (de) * 2003-12-03 2005-06-30 Bayer Cropscience Ag Verfahren zum Identifizieren von fungizid wirksamen Verbindungen basierend auf Pyruvatkinasen aus Pilzen
NZ561009A (en) * 2005-03-16 2009-07-31 Novozymes As Recombinant expression of defensins in filamentous fungi

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1341302C (en) * 1983-02-22 2001-10-09 Rae Lyn Burke Yeast expression systems with vectors having gapdh or pyk promoters and synthesis of foreign protein
US4885249A (en) * 1984-12-05 1989-12-05 Allelix, Inc. Aspergillus niger transformation system
FI864473L (fi) * 1985-11-20 1987-05-21 Panlabs Inc Sammansatta yttryckskassetter foer fungaltransformering.

Also Published As

Publication number Publication date
IE904481A1 (en) 1991-07-31
FI906123A0 (fi) 1990-12-12
MX23984A (es) 1994-02-28
PT96310A (pt) 1991-10-15
DK0439997T3 (da) 1995-12-11
GR3018044T3 (en) 1996-02-29
KR0157411B1 (ko) 1998-10-15
AU6846090A (en) 1991-08-01
ES2079468T3 (es) 1996-01-16
HU210989B (en) 1995-09-28
ATE130034T1 (de) 1995-11-15
FI906123L (fi) 1991-07-30
FI103206B1 (fi) 1999-05-14
JPH05192150A (ja) 1993-08-03
NO905393L (no) 1991-07-30
CA2032035C (en) 2001-08-14
AU645768B2 (en) 1994-01-27
PT96310B (pt) 1998-06-30
DE69023474D1 (de) 1995-12-14
HU908325D0 (en) 1991-07-29
FI103206B (fi) 1999-05-14
JP3329472B2 (ja) 2002-09-30
NO905393D0 (no) 1990-12-13
EP0439997B1 (de) 1995-11-08
IE68457B1 (en) 1996-06-26
CA2032035A1 (en) 1991-07-30
KR910014507A (ko) 1991-08-31
NZ236434A (en) 1992-08-26
DE69023474T2 (de) 1996-03-28
EP0439997A1 (de) 1991-08-07
HUT56886A (en) 1991-10-28
ZA909987B (en) 1991-09-25

Similar Documents

Publication Publication Date Title
NO177318B (no) Fremgangsmåte for fremstilling av prorennin og human-anafylatoksin C5a i Y. lipolytica, samt plasmider til fremstillingen
Lang et al. Efficient expression and secretion of Aspergillus niger RH5344 polygalacturonase in Saccharomyces cerevisiae
JP2633885B2 (ja) 新規な発現系
FI112667B (fi) Uusi sieniproteaasi
JPH06197787A (ja) 新規なるdna分子及び宿主
EP0353188B1 (de) Expressionssystem
NO309283B1 (no) Fremgangsmåte for fremstilling av et polypeptid
NO315330B1 (no) Isolert DNA-molekyl, hybridvektor omfattende denne, Aspergillusstamme defisient i et A. niger asparaginproteasegen, A. niger protease og entransformert vert samt fremgangsmater for a fremstille de ulike elementene
CA2024487C (en) Polygalacturonase encoding fungal expression system
US5447862A (en) Pectin lyase genes of aspergillus niger
CA1312838C (en) Shortened phosphoglycerate kinase promoter
AU644101B2 (en) Polygalacturonase gene from erwinia carotovora and its molecular cloning
KR0179653B1 (ko) 진균 발현 시스템
WO2001066693A1 (en) Compositions and methods for producing high yields of heterologous polypeptides in a pichia cell

Legal Events

Date Code Title Description
MK1K Patent expired