NO310223B1 - Anvendelse av kitosan og et polysakkarid i forbindelse med regenerering av hardt vev, samt implantat - Google Patents

Anvendelse av kitosan og et polysakkarid i forbindelse med regenerering av hardt vev, samt implantat Download PDF

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Publication number
NO310223B1
NO310223B1 NO19970215A NO970215A NO310223B1 NO 310223 B1 NO310223 B1 NO 310223B1 NO 19970215 A NO19970215 A NO 19970215A NO 970215 A NO970215 A NO 970215A NO 310223 B1 NO310223 B1 NO 310223B1
Authority
NO
Norway
Prior art keywords
chitosan
hard tissue
heparin
bone
implant
Prior art date
Application number
NO19970215A
Other languages
English (en)
Norwegian (no)
Other versions
NO970215D0 (no
NO970215L (no
Inventor
Hans-Arne Hansson
Gunilla Johansson-Ruden
Olle Larm
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of NO970215D0 publication Critical patent/NO970215D0/no
Publication of NO970215L publication Critical patent/NO970215L/no
Publication of NO310223B1 publication Critical patent/NO310223B1/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727Heparin; Heparan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/20Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/34Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Transplantation (AREA)
  • Organic Chemistry (AREA)
  • Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)
  • Saccharide Compounds (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO19970215A 1994-07-19 1997-01-17 Anvendelse av kitosan og et polysakkarid i forbindelse med regenerering av hardt vev, samt implantat NO310223B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9402528A SE9402528D0 (sv) 1994-07-19 1994-07-19 Hårdvävnadsstimulerande med el
PCT/SE1995/000857 WO1996002259A1 (en) 1994-07-19 1995-07-13 Hard tissue stimulating agent

Publications (3)

Publication Number Publication Date
NO970215D0 NO970215D0 (no) 1997-01-17
NO970215L NO970215L (no) 1997-01-17
NO310223B1 true NO310223B1 (no) 2001-06-11

Family

ID=20394768

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19970215A NO310223B1 (no) 1994-07-19 1997-01-17 Anvendelse av kitosan og et polysakkarid i forbindelse med regenerering av hardt vev, samt implantat

Country Status (22)

Country Link
US (1) US5894070A (de)
EP (1) EP0771206B1 (de)
JP (1) JP3492377B2 (de)
KR (1) KR100395724B1 (de)
CN (1) CN1081923C (de)
AT (1) ATE219678T1 (de)
BR (1) BR9508322A (de)
CA (1) CA2194462C (de)
CZ (1) CZ289981B6 (de)
DE (1) DE69527203T2 (de)
DK (1) DK0771206T3 (de)
ES (1) ES2178675T3 (de)
FI (1) FI970202A7 (de)
HU (1) HU220770B1 (de)
IS (1) IS1793B (de)
MX (1) MX9700443A (de)
NO (1) NO310223B1 (de)
NZ (1) NZ290219A (de)
PL (1) PL181764B1 (de)
RU (1) RU2153877C2 (de)
SE (1) SE9402528D0 (de)
WO (1) WO1996002259A1 (de)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9402528D0 (sv) * 1994-07-19 1994-07-19 Astra Ab Hårdvävnadsstimulerande med el
KR100237738B1 (ko) * 1997-04-26 2000-01-15 이용찬 생채 매식용 의료기구 임플란트의 기능 향상방법
DE19724869C2 (de) * 1997-06-12 1999-05-12 Henkel Kgaa Verwendung von Citosanderivaten zur Oberflächenbeschichtung
EP0899247B1 (de) * 1997-08-28 2002-11-06 Ngk Spark Plug Co., Ltd Calciumphosphatzement und Calciumphosphatzementzusammensetzung
JP4215884B2 (ja) * 1998-03-23 2009-01-28 日本特殊陶業株式会社 リン酸カルシウムセメント及びリン酸カルシウムセメント組成物
US20030147860A1 (en) * 2002-02-07 2003-08-07 Marchosky J. Alexander Compositions and methods for forming and strengthening bone
CA2335058A1 (en) 1998-06-22 1999-12-29 Danforth Joslyn Method, implant and delivery system for enhancing blood flow in tissue
JP4606586B2 (ja) * 1998-11-10 2011-01-05 株式会社ネーテック 機能性キトサン誘導体
FR2791262B1 (fr) * 1999-03-22 2001-09-28 Virbac Sa Compositions a base de chondroitine et de chitosan pour la protection, le traitement ou le remplacement des tissus conjonctifs
WO2001000792A1 (en) 1999-06-29 2001-01-04 Marchosky J Alexander Compositions and methods for forming and strengthening bone
GB9920393D0 (en) * 1999-08-27 1999-11-03 Medix Scient Uk Limited Plant extract mixtures and their uses
FI19991852A7 (fi) 1999-09-01 2001-03-02 Yli Urpo Antti Uusi monikerroksinen materiaali, joka käsittää vaikuttavan ainesosan, ja sen valmistus
AU1375301A (en) * 1999-11-15 2001-05-30 Bio Syntech Canada Inc Temperature-controlled and ph-dependant self-gelling biopolymeric aqueous solution
US20030158302A1 (en) * 1999-12-09 2003-08-21 Cyric Chaput Mineral-polymer hybrid composition
ATE243049T1 (de) * 1999-12-09 2003-07-15 Biosyntech Canada Inc Mineral-polymer hybrid-zusammensetzung
KR100880622B1 (ko) * 2000-06-29 2009-01-30 바이오신텍 캐나다 인코포레이티드 연골 및 다른 조직의 복구 및 재생용 조성물 및 방법
ES2169681B1 (es) * 2000-08-10 2003-10-01 Osfarma S L Metodo de produccion de filmes de quitosan con una alta capacidad de adherencia celular, producto obrenido y aplicaciones.
AU2002221370A1 (en) * 2000-11-15 2002-05-27 Bio Syntech Canada Inc Method for restoring a damaged or degenerated intervertebral disc
RU2212243C2 (ru) * 2001-06-15 2003-09-20 Щиголева Светлана Александровна Препарат "сха" для лечения кожных заболеваний
ES2353116T3 (es) * 2002-07-16 2011-02-25 Bio Syntech Canada Inc. Composiciones para disoluciones de quitosano citocompatibles, inyectables, autogelificantes para encapsular y administrar células vivas o factores biológicamente activos.
US20040054414A1 (en) 2002-09-18 2004-03-18 Trieu Hai H. Collagen-based materials and methods for augmenting intervertebral discs
FR2844717B1 (fr) * 2002-09-23 2006-07-07 Richard Cancel Plaque de renfort comprenant notamment du chitosane
RU2294751C2 (ru) * 2002-09-30 2007-03-10 Реджен Байотек, Инк. Композиция для стимулирования образования костной ткани и сращения кости
JP2006515765A (ja) * 2002-11-15 2006-06-08 エスディージーアイ・ホールディングス・インコーポレーテッド 滑膜性関節を治療するためのコラーゲンベース材料および方法
US20040186471A1 (en) * 2002-12-07 2004-09-23 Sdgi Holdings, Inc. Method and apparatus for intervertebral disc expansion
DE10338110A1 (de) * 2003-08-15 2005-03-10 Biomet Deutschland Gmbh Mit Chitosan beschichteter metallischer Gegenstand sowie Verfahren zu dessen Herstellung
CA2535169A1 (en) * 2003-12-31 2005-07-21 Osteotech, Inc. Improved bone matrix compositions and methods
US20070231788A1 (en) * 2003-12-31 2007-10-04 Keyvan Behnam Method for In Vitro Assay of Demineralized Bone Matrix
FR2866571B1 (fr) * 2004-02-20 2007-09-21 Philippe Zanchetta Utilisation d'un melange de polysaccharides specifiques denomme par l'inventeur ezbone, comprenant de l'acide hyaluronique, de la chondroitine 6 sulfate, du dermatane sulfate et de l'heparine en cicatrisation osseuse.
CA2565913A1 (en) * 2004-05-07 2005-11-17 The University Of Queensland Composition for stimulating bone growth and differentiation and method for isolating same
AU2005239977B2 (en) * 2004-05-07 2010-11-11 The University Of Queensland Composition for stimulating bone growth and differentiation and method for isolating same
KR101322889B1 (ko) 2004-08-16 2013-10-30 셀리서치 코포레이션 피티이 리미티드 제대의 양막으로부터 줄기/전구세포의 추출
EP1838335A1 (de) * 2005-01-19 2007-10-03 Bonoss Medical AB Wachstumsfaktoren-zusammensetzung
EP1937326B1 (de) 2005-10-21 2018-09-12 CellResearch Corporation Pte Ltd Isolierung und züchtung von stamm/vorläuferzellen aus dem amnion der nabelschnur und verwendung von daraus differenzierten zellen
CA2627907C (en) * 2005-11-01 2014-06-17 Osteotech, Inc. Osteoinductive composition comprising osteoinductive factors recovered from mineralized bone and a carrier
WO2007051311A1 (en) * 2005-11-04 2007-05-10 Bio Syntech Canada Inc. Gel formation of polyelectrolyte aqueous solutions by thermally induced changes in ionization state
DE102006020035A1 (de) * 2006-04-26 2007-10-31 B. Braun Melsungen Ag Herstellung und Verwendung von Poly(hydroxyethylstärke)chitin- und Poly(Carboxymethylstärke)chitin-Verbindungen
US8399619B2 (en) * 2006-06-30 2013-03-19 Warsaw Orthopedic, Inc. Injectable collagen material
US8118779B2 (en) * 2006-06-30 2012-02-21 Warsaw Orthopedic, Inc. Collagen delivery device
EP1977739A1 (de) * 2007-04-03 2008-10-08 Bioiberica, S.A. Nanoteilchenförmige Zusammensetzung von Chitosan und Chondroitinsulfat
US9554920B2 (en) 2007-06-15 2017-01-31 Warsaw Orthopedic, Inc. Bone matrix compositions having nanoscale textured surfaces
CA3062443C (en) * 2007-06-15 2022-03-15 Warsaw Orthopedic, Inc. Method of treating tissue
CA2690457C (en) 2007-06-15 2018-02-20 Osteotech, Inc. Bone matrix compositions and methods
WO2008157492A2 (en) * 2007-06-15 2008-12-24 Osteotech, Inc. Osteoinductive demineralized cancellous bone
US9358113B2 (en) * 2007-07-10 2016-06-07 Warsaw Orthopedic, Inc. Delivery system
US20110054408A1 (en) * 2007-07-10 2011-03-03 Guobao Wei Delivery systems, devices, tools, and methods of use
EP2211921B1 (de) * 2007-10-19 2013-12-25 Warsaw Orthopedic, Inc. Demineralisierte knochenmatrix-zusammensetzungen und verfahren
GB2463474B (en) 2008-09-11 2012-05-02 Agency Science Tech & Res Therapeutic bone growth and regeneration
RU2383564C1 (ru) * 2008-11-21 2010-03-10 Астемир Икрамович Шайхалиев Композиция - остеоиндуктор и остеокондуктор, при лечении костной патологии в стоматологии и челюстно-лицевой хирургии, и способ получения композиции - остеоиндуктора и остеокондуктора, при лечении костной патологии в стоматологии и челюстно-лицевой хирургии
WO2010093955A1 (en) * 2009-02-12 2010-08-19 Osteotech,Inc. Segmented delivery system
CN104039356B (zh) 2012-01-27 2018-08-17 弗·哈夫曼-拉罗切有限公司 用于靶向递送的、与小分子整联蛋白拮抗剂共价连接的壳聚糖
WO2014152796A2 (en) 2013-03-14 2014-09-25 Hemcon Medical Technologies, Inc. Biocompatible and bioabsorbable derivatized chitosan compositions
CN105126165B (zh) * 2015-01-21 2017-12-08 中国人民解放军第三〇七医院 一种钛牙种植体材料及其制备方法与应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL163522B (nl) * 1970-07-20 1980-04-15 Montedison Spa Werkwijze om een katalysator te bereiden voor de polymerisatie van alkenen-1.
US4326532A (en) * 1980-10-06 1982-04-27 Minnesota Mining And Manufacturing Company Antithrombogenic articles
SE8200751L (sv) * 1982-02-09 1983-08-10 Olle Larm Forfarande for kovalent koppling for framstellning av konjugat och hervid erhallna produkter
JPS61253065A (ja) * 1985-05-02 1986-11-10 片倉チツカリン株式会社 キトサン誘導体およびコラ−ゲンの複合材の医用材料およびその製造法
US5510418A (en) * 1988-11-21 1996-04-23 Collagen Corporation Glycosaminoglycan-synthetic polymer conjugates
US5256447A (en) * 1991-12-31 1993-10-26 Minnesota Mining And Manufacturing Company Adhesive composition and method
BR9207010A (pt) * 1991-12-31 1995-12-05 Minnesota Mining & Mfg Composição adesiva e processo de aderência de um material restaurador a um substrato
SE9402528D0 (sv) * 1994-07-19 1994-07-19 Astra Ab Hårdvävnadsstimulerande med el

Also Published As

Publication number Publication date
IS1793B (is) 2001-12-12
RU2153877C2 (ru) 2000-08-10
HU220770B1 (hu) 2002-05-28
NO970215D0 (no) 1997-01-17
CN1157568A (zh) 1997-08-20
FI970202A0 (fi) 1997-01-17
JPH10502664A (ja) 1998-03-10
DE69527203D1 (de) 2002-08-01
HUT77607A (hu) 1998-06-29
ATE219678T1 (de) 2002-07-15
PL318326A1 (en) 1997-06-09
IS4409A (is) 1997-01-06
FI970202L (fi) 1997-01-17
CN1081923C (zh) 2002-04-03
SE9402528D0 (sv) 1994-07-19
JP3492377B2 (ja) 2004-02-03
HU9700160D0 (en) 1997-03-28
CA2194462C (en) 2007-07-10
KR100395724B1 (ko) 2004-02-18
ES2178675T3 (es) 2003-01-01
US5894070A (en) 1999-04-13
CA2194462A1 (en) 1996-02-01
EP0771206B1 (de) 2002-06-26
AU3089595A (en) 1996-02-16
DK0771206T3 (da) 2002-08-19
KR970704459A (ko) 1997-09-06
PL181764B1 (pl) 2001-09-28
MX9700443A (es) 1997-04-30
WO1996002259A1 (en) 1996-02-01
CZ289981B6 (cs) 2002-05-15
EP0771206A1 (de) 1997-05-07
NZ290219A (en) 1998-06-26
FI970202A7 (fi) 1997-01-17
CZ14097A3 (en) 1997-07-16
BR9508322A (pt) 1998-01-06
DE69527203T2 (de) 2003-01-09
NO970215L (no) 1997-01-17
AU696183B2 (en) 1998-09-03

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