ATE243049T1 - Mineral-polymer hybrid-zusammensetzung - Google Patents

Mineral-polymer hybrid-zusammensetzung

Info

Publication number
ATE243049T1
ATE243049T1 AT00981124T AT00981124T ATE243049T1 AT E243049 T1 ATE243049 T1 AT E243049T1 AT 00981124 T AT00981124 T AT 00981124T AT 00981124 T AT00981124 T AT 00981124T AT E243049 T1 ATE243049 T1 AT E243049T1
Authority
AT
Austria
Prior art keywords
calcium phosphate
liquid
phosphates
thermo
admixed
Prior art date
Application number
AT00981124T
Other languages
English (en)
Inventor
Cyril Chaput
El Zein Annabelle Rodrigues
Original Assignee
Biosyntech Canada Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biosyntech Canada Inc filed Critical Biosyntech Canada Inc
Application granted granted Critical
Publication of ATE243049T1 publication Critical patent/ATE243049T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0047Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L24/0052Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with an inorganic matrix
    • A61L24/0063Phosphorus containing materials, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0047Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L24/0073Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix
    • A61L24/0084Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix containing fillers of phosphorus-containing inorganic compounds, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/08Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/20Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24Collagen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/30Inorganic materials
    • A61L27/32Phosphorus-containing materials, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/42Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
    • A61L27/425Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of phosphorus containing material, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52Hydrogels or hydrocolloids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/06Flowable or injectable implant compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials Engineering (AREA)
  • Composite Materials (AREA)
  • Surgery (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
AT00981124T 1999-12-09 2000-12-08 Mineral-polymer hybrid-zusammensetzung ATE243049T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16995499P 1999-12-09 1999-12-09
PCT/CA2000/001489 WO2001041821A1 (en) 1999-12-09 2000-12-08 Mineral-polymer hybrid composition

Publications (1)

Publication Number Publication Date
ATE243049T1 true ATE243049T1 (de) 2003-07-15

Family

ID=22617898

Family Applications (2)

Application Number Title Priority Date Filing Date
AT00981124T ATE243049T1 (de) 1999-12-09 2000-12-08 Mineral-polymer hybrid-zusammensetzung
AT00982802T ATE247495T1 (de) 1999-12-09 2000-12-08 Mineral-polymer hybrid-zusammensetzung

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT00982802T ATE247495T1 (de) 1999-12-09 2000-12-08 Mineral-polymer hybrid-zusammensetzung

Country Status (6)

Country Link
US (2) US20030199615A1 (de)
EP (2) EP1237585B1 (de)
AT (2) ATE243049T1 (de)
AU (2) AU1979201A (de)
DE (2) DE60004710T2 (de)
WO (2) WO2001041821A1 (de)

Families Citing this family (133)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1375301A (en) 1999-11-15 2001-05-30 Bio Syntech Canada Inc Temperature-controlled and ph-dependant self-gelling biopolymeric aqueous solution
ATE243049T1 (de) * 1999-12-09 2003-07-15 Biosyntech Canada Inc Mineral-polymer hybrid-zusammensetzung
US20030158302A1 (en) * 1999-12-09 2003-08-21 Cyric Chaput Mineral-polymer hybrid composition
US7820191B2 (en) 2000-04-28 2010-10-26 Skeletal Kinetics, Llc Calcium phosphate cements prepared from silicate solutions
KR100880622B1 (ko) 2000-06-29 2009-01-30 바이오신텍 캐나다 인코포레이티드 연골 및 다른 조직의 복구 및 재생용 조성물 및 방법
WO2002040072A2 (en) * 2000-11-15 2002-05-23 Bio Syntech Canada Inc. Filler composition for soft tissue augmentation and reconstructive surgery
AU2002221370A1 (en) * 2000-11-15 2002-05-27 Bio Syntech Canada Inc Method for restoring a damaged or degenerated intervertebral disc
US20020114795A1 (en) 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
US20030134811A1 (en) * 2001-10-09 2003-07-17 John Jackson Methods and compositions comprising hydroxyapatite useful for the administration of therapeutic agents
JP2003128704A (ja) 2001-10-24 2003-05-08 Matsumoto Shika Univ キチン・キトサンの低分子化方法及び骨伝導物の製造方法
US20030204180A1 (en) 2002-04-30 2003-10-30 Kimberly-Clark Worldwide, Inc. Temperature responsive delivery systems
US7273523B2 (en) 2002-06-07 2007-09-25 Kyphon Inc. Strontium-apatite-cement-preparations, cements formed therefrom, and uses thereof
US7244445B2 (en) * 2002-07-29 2007-07-17 Poly Med, Inc Conformable, absorbable, solid composite preforms and their use for bone tissue engineering
AU2002337479A1 (en) * 2002-09-04 2004-03-29 Hadasit Medical Research Services & Development Ltd. Compositions comprising bone marrow cells, demineralized bone matrix and rtg polymers for use in the induction of bone and cartilage formation
AU2003287812A1 (en) * 2002-12-03 2004-06-23 Bio Syntech Canada Inc. Method for treating a tumor using a thermo-gelling chitosan composition
US7371256B2 (en) 2002-12-16 2008-05-13 Poly-Med, Inc Composite vascular constructs with selectively controlled properties
FR2850282B1 (fr) 2003-01-27 2007-04-06 Jerome Asius Implant injectable a base de ceramique pour le comblement de rides, depressions cutanees et cicatrices, et sa preparation
JP4634027B2 (ja) * 2003-05-16 2011-02-16 花王株式会社 ビタミンd様活性代替用剤
US7306786B2 (en) * 2003-07-28 2007-12-11 Skeletal Kinetics, Llc Calcium phosphate cements comprising a water-soluble contrast agent
US7261718B2 (en) * 2003-09-11 2007-08-28 Skeletal Kinetics Llc Use of vibration with polymeric bone cements
US7261717B2 (en) * 2003-09-11 2007-08-28 Skeletal Kinetics Llc Methods and devices for delivering orthopedic cements to a target bone site
EP1523985B1 (de) 2003-10-17 2010-03-10 Oy Neurofood Ab Nicht-radioaktives Strontiummittel zur Behandlung von Krebs
US7252833B2 (en) 2003-11-18 2007-08-07 Skeletal Kinetics, Llc Calcium phosphate cements comprising an osteoclastogenic agent
EP1740233A1 (de) * 2004-03-08 2007-01-10 Dr.h.c. Robert Mathys Stiftung Hydraulischer zement auf basis von calciumphosphat für chirurgische anwendungen
US9707024B2 (en) 2004-03-09 2017-07-18 Skeletal Kinetics, Llc Use of vibration in composite fixation
US8118812B2 (en) 2004-03-09 2012-02-21 Skeletal Kinetics, Llc Use of vibration in composite fixation
KR20060134223A (ko) 2004-04-27 2006-12-27 키폰 인크. 뼈 대체 조성물 및 사용 방법
FR2869544B1 (fr) * 2004-05-03 2006-07-21 Centre Nat Rech Scient Cnrse Composition pour ciment injectable, utile comme substitut osseux
US7252841B2 (en) * 2004-05-20 2007-08-07 Skeletal Kinetics, Llc Rapid setting calcium phosphate cements
US20050257714A1 (en) * 2004-05-20 2005-11-24 Constantz Brent R Orthopedic cements comprising a barium apatite contrast agent
US8119153B2 (en) 2004-08-26 2012-02-21 Boston Scientific Scimed, Inc. Stents with drug eluting coatings
US9078884B2 (en) 2004-09-21 2015-07-14 Thomas Joseph Lally Bio-material composition and method for spinal fusion
KR101420100B1 (ko) * 2004-09-21 2014-07-30 토마스 죠셉 랠리 다목적 생체재료 조성물
US20060074422A1 (en) * 2004-09-27 2006-04-06 Story Brooks J Suture anchor and void filler combination
US20060067971A1 (en) * 2004-09-27 2006-03-30 Story Brooks J Bone void filler
US7473678B2 (en) 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
US8114841B2 (en) 2004-10-14 2012-02-14 Biomimetic Therapeutics, Inc. Maxillofacial bone augmentation using rhPDGF-BB and a biocompatible matrix
US20060083769A1 (en) * 2004-10-14 2006-04-20 Mukesh Kumar Method and apparatus for preparing bone
CN102342889A (zh) 2004-11-16 2012-02-08 3M创新有限公司 包括酪蛋白酸盐的牙科组合物及其应用
KR101277869B1 (ko) * 2004-11-16 2013-07-30 쓰리엠 이노베이티브 프로퍼티즈 컴파니 포스페이트 염을 포함하는 치과용 충전제 및 조성물
AU2005306857A1 (en) 2004-11-16 2006-05-26 3M Innovative Properties Company Dental compositions with calcium phosphorus releasing glass
CN101115459B (zh) 2004-11-16 2012-03-21 3M创新有限公司 包括含磷表面处理的牙科填料
DE102005034420A1 (de) * 2004-12-23 2006-07-06 Ossacur Ag Gelartiges Material zur Füllung von Knochen- und/oder Knorpeldefekten
US20080119859A1 (en) * 2005-01-12 2008-05-22 Lally Thomas J Multi-Purpose Bio-Material Composition
EP1838335A1 (de) * 2005-01-19 2007-10-03 Bonoss Medical AB Wachstumsfaktoren-zusammensetzung
US7459018B2 (en) 2005-04-08 2008-12-02 Howmedica Leibinger Inc. Injectable calcium phosphate cement
US7416602B2 (en) 2005-04-08 2008-08-26 Howmedica Leibinger, Inc. Calcium phosphate cement
US20090148486A1 (en) * 2005-04-28 2009-06-11 Helen Lu Compositions and methods for treating pulp inflammations caused by infection or trauma
US7651701B2 (en) 2005-08-29 2010-01-26 Sanatis Gmbh Bone cement composition and method of making the same
US9101436B2 (en) * 2005-10-21 2015-08-11 Ada Foundation Dental and endodontic filling materials and methods
WO2007059605A1 (en) * 2005-11-04 2007-05-31 Bio Syntech Canada Inc. Composition and method for efficient delivery of nucleic acids to cells using chitosan
WO2007064304A1 (en) * 2005-12-01 2007-06-07 National University Of Singapore Biocompatible composition and uses thereof
US7674864B2 (en) * 2005-12-23 2010-03-09 Boston Scientific Scimed, Inc. Polymeric hybrid precursors, polymeric hybrid precursor composite matrices, medical devices, and methods
US8455088B2 (en) 2005-12-23 2013-06-04 Boston Scientific Scimed, Inc. Spun nanofiber, medical devices, and methods
US10130561B2 (en) * 2006-01-31 2018-11-20 Robert L. Karlinsey Functionalized calcium phosphate hybrid systems for confectionery and foodstuff applications
ES2427993T3 (es) 2006-02-09 2013-11-05 Biomimetic Therapeutics, Llc Composiciones y métodos para el tratamiento de hueso
US20070258916A1 (en) * 2006-04-14 2007-11-08 Oregon Health & Science University Oral compositions for treating tooth hypersensitivity
US7507286B2 (en) 2006-06-08 2009-03-24 Sanatis Gmbh Self-foaming cement for void filling and/or delivery systems
US9161967B2 (en) 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
CA2656278C (en) 2006-06-30 2016-02-09 Biomimetic Therapeutics, Inc. Compositions and methods for treating rotator cuff injuries
DE102006042142A1 (de) 2006-09-06 2008-03-27 Curasan Ag Phasen- und sedimentationsstabile, plastisch verformbare Zubereitung mit intrinsischer Porenbildung, bspw. zum Auffüllen von Knochendefekten bzw. zur Verwendung als Knochenersatzmaterial, und Verfahren zu deren Herstellung
KR100784134B1 (ko) * 2006-10-09 2007-12-12 주식회사 대웅 상피세포성장인자를 함유하는 안정한 구내염 치료용 액상조성물
US8106008B2 (en) 2006-11-03 2012-01-31 Biomimetic Therapeutics, Inc. Compositions and methods for arthrodetic procedures
NL1032851C2 (nl) * 2006-11-10 2008-05-14 Fondel Finance B V Kit en werkwijze voor het fixeren van een prothese of deel daarvan en/of het vullen van benige defecten.
CA2642940A1 (en) * 2006-12-22 2008-07-03 Mathys Ag Bettlach Precursor for the preparation of a pasty bone replacement material by admixture of a liquid
US9205036B2 (en) 2007-01-31 2015-12-08 Robert Karlinsey Dental composition
US9023373B2 (en) * 2007-01-31 2015-05-05 Indiana Nanotech Functionalized calcium phosphate hybrid systems for the remineralization of teeth and a method for producing the same
US20100203144A1 (en) * 2007-08-23 2010-08-12 University Of Virginia Patent Foundation Immobilized Metallic Nanoparticles as Unique Materials for Therapeutic and Biosensor Applications
US20110136935A1 (en) * 2007-08-30 2011-06-09 National University Of Singapore Bone and/or dental cement composition and uses thereof
US20110171607A1 (en) * 2007-10-25 2011-07-14 The Trustees Of Columbia University In The City Of New York Biopulp
US20110097408A1 (en) * 2007-12-10 2011-04-28 O'malley Bert W Chitosan-based matrices and uses thereof
US20100323022A1 (en) * 2008-02-07 2010-12-23 Kuraray Medical Inc. Calcium phosphate composition and process for production thereof
EP2259807B1 (de) 2008-02-07 2013-04-24 Biomimetic Therapeutics, Inc. Zusammensetzungen zur distraktionsosteogenese
SI2280720T1 (sl) 2008-03-27 2019-06-28 Purdue Research Foundation Sintetični peptidoglikani,ki vežejo kolagen, priprava in postopki uporabe
US7968616B2 (en) 2008-04-22 2011-06-28 Kyphon Sarl Bone cement composition and method
KR20110067035A (ko) 2008-09-09 2011-06-20 바이오미메틱 세라퓨틱스, 인크. 건 및 인대 손상의 치료를 위한 혈소판-유래 성장 인자 조성물 및 방법
US8709149B2 (en) 2008-11-12 2014-04-29 Ossdsign Ab Hydraulic cements, methods and products
US10105197B1 (en) * 2009-03-26 2018-10-23 Fernando Colon Method of treatment for periodontal pockets
US20140271351A1 (en) * 2009-12-21 2014-09-18 Coloplast A/S Wetting media of glycerol and buffer
US8883739B2 (en) 2010-01-19 2014-11-11 The Trustees Of Columbia University In The City Of New York Osteocalcin as a treatment for male reproductive disorders
CN102811622A (zh) 2010-02-22 2012-12-05 生物模拟治疗公司 用于治疗腱病的血小板衍生生长因子组合物和方法
AU2011224893B2 (en) 2010-03-10 2015-01-22 Ossdsign Ab Implants and methods for correcting tissue defects
US8614190B2 (en) * 2010-06-30 2013-12-24 Industrial Technology Research Institute Thermal responsive composition for treating bone diseases
US10182973B2 (en) 2010-11-10 2019-01-22 Stryker European Holdings I, Llc Polymeric bone foam composition and method
DE102010055561B4 (de) * 2010-12-23 2015-12-31 Heraeus Medical Gmbh Beschichtungsverfahren und Beschichtungsvorrichtung
US11389663B2 (en) 2011-04-01 2022-07-19 Bioregentech, Inc. Laser assisted wound healing protocol and system
US11745026B2 (en) 2011-04-01 2023-09-05 The Bioregentech Institute, Inc. Laser assisted wound healing protocol and system
US11730760B2 (en) 2011-04-01 2023-08-22 The Bioregentech Institute, Inc. Laser assisted wound healing protocol and system
HRP20170482T1 (hr) 2011-05-24 2017-05-19 Symic Ip, Llc Sintetski peptidoglikani koji vežu hijaluronsku kiselinu, dobivanje, i postupci uporabe
TWI423828B (zh) * 2011-08-17 2014-01-21 Univ Nat Cheng Kung 供低骨質密度患者使用之骨植入物
US9463046B2 (en) 2011-08-22 2016-10-11 Ossdsign Ab Implants and methods for using such implants to fill holes in bone tissue
US8591645B2 (en) 2011-09-09 2013-11-26 Ossdsign Ab Hydraulic cements with optimized grain size distribution, methods, articles and kits
US20130066327A1 (en) 2011-09-09 2013-03-14 Håkan Engqvist Hydraulic cement compositions with low ph methods, articles and kits
CN103014801A (zh) * 2011-09-20 2013-04-03 天津市玄真生物医药科技发展有限公司 一种钛基羟基磷灰石生物医用复合材料的电沉积制备方法
CN102492974A (zh) * 2011-12-30 2012-06-13 浙江大学 钛种植体表面制备可降解镁掺杂非晶态磷酸钙涂层的方法
JP6232048B2 (ja) 2012-04-23 2017-11-15 ジェニス エイチエフ. 骨移植片代用材としての部分的に脱アセチル化されたキチンを含む自硬性の生体活性セメント組成物
CN102899698A (zh) * 2012-09-29 2013-01-30 浙江大学 金属钛表面制备羟基磷灰石树枝状微纳复合涂层电化学法
US9272072B1 (en) 2012-10-19 2016-03-01 Nuvasive, Inc. Osteoinductive bone graft substitute
WO2014091469A1 (en) 2012-12-14 2014-06-19 Ossdsign Ab Cement-forming compositions, monetite cements, implants and methods for correcting bone defects
US10076416B2 (en) 2013-02-12 2018-09-18 Ossdsign Ab Mosaic implants, kits and methods for correcting bone defects
US20140272803A1 (en) * 2013-03-14 2014-09-18 Alan Nevins Root canal for tissue in-growth
WO2014152497A2 (en) 2013-03-15 2014-09-25 The Trustees Of Columbia University In The City Of New York Osteocalcin as a treatment for cognitive disorders
US9200039B2 (en) 2013-03-15 2015-12-01 Symic Ip, Llc Extracellular matrix-binding synthetic peptidoglycans
EP2983643A4 (de) 2013-04-12 2016-12-28 Univ Columbia Verfahren für wirtszellen-homing und zahnmarkregeneration
WO2014172459A2 (en) * 2013-04-16 2014-10-23 Molecular Systems, Ltd. Laser assisted periodontium and osseus regeneration protocol
GB201313898D0 (en) * 2013-08-02 2013-09-18 Bradford Formulations and materials with cationic polymers
US9192692B2 (en) 2013-10-24 2015-11-24 Medtronic Xomed, Inc. Chitosan stenting paste
US9192574B2 (en) 2013-10-24 2015-11-24 Medtronic Xomed, Inc. Chitosan paste wound dressing
CN103816572A (zh) * 2014-03-03 2014-05-28 张宪 一种可注射多孔磷酸钙骨修复材料的制备方法
WO2015164822A1 (en) 2014-04-25 2015-10-29 Purdue Research Foundation Collagen binding synthetic peptidoglycans for treatment of endothelial dysfunction
ES2555235B1 (es) * 2014-06-25 2016-10-05 Universitat Politècnica De Catalunya Nuevo proceso de fabricación en un solo paso de biomateriales espumados
EP3179961B1 (de) 2014-08-14 2020-12-02 OssDsign AB Knochenimplantate zur korrektur von knochendefekten
EP3226889A4 (de) 2014-11-19 2018-11-21 The Trustees of Columbia University in the City of New York Osteocalcin zur behandlung von gebrechlichkeit im zusammenhang mit alterung
MX374683B (es) 2015-11-03 2025-03-04 Zoetis Services Llc Compuestos polimericos sol-gel y sus usos.
US12318475B2 (en) 2016-03-14 2025-06-03 The University Of Chicago Injectable pastes based on oppositely charged polymer/calcium phosphate nanoparticles
EP3228334A1 (de) 2016-04-06 2017-10-11 Graftys Blut-enthaltende phosphorcalciumhaltige zementzusammensetzung
RU2617050C1 (ru) * 2016-04-11 2017-04-19 Виталий Васильевич Гузеев Биоактивный композиционный материал для замещения костных дефектов и способ его получения
RU2018141386A (ru) 2016-04-27 2020-05-27 Аника Терапьютикс, Инк. Композиция для применения в лечении дегенерации сухожилий
CA3021765A1 (en) * 2016-04-27 2017-11-02 Anika Therapeutics, Inc. Methods and compositions for the treatment of degenerate bone
US10709733B2 (en) 2016-08-11 2020-07-14 Regents Of The University Of Minnesota Nonsurgical techniques for restoring tooth enamel
EP3538001B1 (de) * 2016-11-10 2026-01-14 The BioRegenTech Institute, Inc. Led-gestütztes wundheilungssystem
US11654293B2 (en) 2016-11-10 2023-05-23 The Bioregentech Institute, Inc. Laser assisted wound healing protocol and system
CN110573066A (zh) * 2017-03-02 2019-12-13 光谱Md公司 用于多光谱截肢部位分析的机器学习系统和技术
US20180326124A1 (en) * 2017-05-12 2018-11-15 Bone Solutions, Inc. Bio-Material Composition and Methods of Use
WO2019010484A2 (en) 2017-07-07 2019-01-10 Symic Ip, Llc SYNTHETIC BIOCONJUGATES
EP3651743B1 (de) 2017-07-14 2023-10-04 The University of Chicago Gefriergetrocknete formulierungen mit nanopartikeln und verfahren zur gefriertrocknung
CN108853599B (zh) * 2018-07-27 2021-03-05 王宇清 一种富氧温敏型水凝胶及其制备方法
BR112021007281A2 (pt) 2018-10-16 2021-07-20 Ossdsign Ab implantes para preencher orifícios perfurados no osso e métodos para preencher orifícios perfurados no osso
CN111214699A (zh) * 2020-01-08 2020-06-02 广州贝奥吉因生物科技股份有限公司 一种用于周围神经损伤修复的水凝胶及其制备方法
US12343444B2 (en) 2021-08-16 2025-07-01 Bone Solutions, Inc. Structural implant to prevent bone defects
CN113769160A (zh) * 2021-08-23 2021-12-10 广州润虹医药科技股份有限公司 一种温敏性微球及其即用型温敏性磷酸钙骨水泥
CN115778845B (zh) * 2023-02-07 2023-04-25 荷本世新(北京)生物科技有限公司 蛋白组合物及其制备方法和用途
CN118370689A (zh) * 2024-04-29 2024-07-23 桂林凯文彼德科技有限公司 锶掺杂根管填充糊剂、其制备方法及其应用

Family Cites Families (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51136033A (en) * 1975-05-19 1976-11-25 Nissan Motor Co Ltd Exhaust reflux device of engine
US4185618A (en) * 1976-01-05 1980-01-29 Population Research, Inc. Promotion of fibrous tissue growth in fallopian tubes for female sterilization
US4391909A (en) * 1979-03-28 1983-07-05 Damon Corporation Microcapsules containing viable tissue cells
US4394373A (en) * 1981-04-06 1983-07-19 Malette William Graham Method of achieving hemostasis
US4424346A (en) * 1981-06-04 1984-01-03 Canadian Patents And Development Ltd. Derivatives of chitins, chitosans and other polysaccharides
SE441009B (sv) * 1982-03-08 1985-09-02 Kjell Nilsson Sett att immobilisera levande biomaterial i perlformiga polymerer
US4474769A (en) * 1983-05-13 1984-10-02 Pfanstiehl Laboratories, Inc. Chitosan as a contraceptive
US4659700A (en) * 1984-03-02 1987-04-21 Johnson & Johnson Products, Inc. Chitosan-glycerol-water gel
US4722948A (en) * 1984-03-16 1988-02-02 Dynatech Corporation Bone replacement and repair putty material from unsaturated polyester resin and vinyl pyrrolidone
US4731081A (en) * 1984-09-11 1988-03-15 Mentor Corporation Rupture-resistant prosthesis with creasable shell and method of forming same
US4895724A (en) 1985-06-07 1990-01-23 Pfizer Inc. Chitosan compositions for controlled and prolonged release of macromolecules
JPS624702A (ja) * 1985-06-28 1987-01-10 Lion Corp 水溶性アシル化キトサンの製造方法
US6005161A (en) * 1986-01-28 1999-12-21 Thm Biomedical, Inc. Method and device for reconstruction of articular cartilage
US5902741A (en) * 1986-04-18 1999-05-11 Advanced Tissue Sciences, Inc. Three-dimensional cartilage cultures
US4803075A (en) * 1986-06-25 1989-02-07 Collagen Corporation Injectable implant composition having improved intrudability
US5736372A (en) * 1986-11-20 1998-04-07 Massachusetts Institute Of Technology Biodegradable synthetic polymeric fibrous matrix containing chondrocyte for in vivo production of a cartilaginous structure
CA1340581C (en) * 1986-11-20 1999-06-08 Joseph P. Vacanti Chimeric neomorphogenesis of organs by controlled cellular implantation using artificial matrices
DE3869850D1 (de) * 1987-07-10 1992-05-14 Asahi Optical Co Ltd Zusammensetzung zur herstellung eines haertbaren kalziumphosphatartigen materials und verfahren zur produktion eines derartigen materials.
US6610669B1 (en) 1987-09-18 2003-08-26 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
GB8803697D0 (en) * 1988-02-17 1988-03-16 Deltanine Research Ltd Clinical developments using amniotic membrane cells
US4956350A (en) * 1988-08-18 1990-09-11 Minnesota Mining And Manufacturing Company Wound filling compositions
US4938763B1 (en) 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
US5126141A (en) * 1988-11-16 1992-06-30 Mediventures Incorporated Composition and method for post-surgical adhesion reduction with thermo-irreversible gels of polyoxyalkylene polymers and ionic polysaccharides
US5073202A (en) 1989-03-09 1991-12-17 Micro Vesicular Systems, Inc. Method of using a biodegradable superabsorbing sponge
US5324519A (en) 1989-07-24 1994-06-28 Atrix Laboratories, Inc. Biodegradable polymer composition
US5811094A (en) * 1990-11-16 1998-09-22 Osiris Therapeutics, Inc. Connective tissue regeneration using human mesenchymal stem cell preparations
US5318780A (en) 1991-10-30 1994-06-07 Mediventures Inc. Medical uses of in situ formed gels
GB2261672A (en) * 1991-11-18 1993-05-26 Michael Braden The use of biomaterials for tissue repair
IL100096A (en) * 1991-11-20 1996-03-31 Univ Ramot Method for entrapment of active materials in chitosan
US5658593A (en) * 1992-01-16 1997-08-19 Coletica Injectable compositions containing collagen microcapsules
US5708152A (en) 1992-03-27 1998-01-13 Ciba Specialty Chemicals Corporation N-substituted chitosan derivatives in a process for their preparation
US5266326A (en) * 1992-06-30 1993-11-30 Pfizer Hospital Products Group, Inc. In situ modification of alginate
US5871985A (en) * 1992-09-28 1999-02-16 Brown University Research Foundation Particulate non cross-linked chitosan core matrices for encapsulated cells
US5709854A (en) * 1993-04-30 1998-01-20 Massachusetts Institute Of Technology Tissue formation by injecting a cell-polymeric solution that gels in vivo
US5368051A (en) * 1993-06-30 1994-11-29 Dunn; Allan R. Method of regenerating articular cartilage
CA2130295A1 (en) 1993-08-26 1995-02-27 Richard A. Berg Ionically crosslinked glycosaminoglycan gels for soft tissue augmentation and drug delivery
US5531716A (en) 1993-09-29 1996-07-02 Hercules Incorporated Medical devices subject to triggered disintegration
US6743783B1 (en) 1993-12-01 2004-06-01 Marine Polymer Technologies, Inc. Pharmaceutical compositions comprising poly-β-1→4-N-acetylglucosamine
US5422116A (en) * 1994-02-18 1995-06-06 Ciba-Geigy Corporation Liquid ophthalmic sustained release delivery system
US6251137B1 (en) 1994-03-23 2001-06-26 Mcghan Medical Corporation Synthetic triglyceride filler material for surgically implanted prostheses
US5626861A (en) * 1994-04-01 1997-05-06 Massachusetts Institute Of Technology Polymeric-hydroxyapatite bone composite
US5723331A (en) * 1994-05-05 1998-03-03 Genzyme Corporation Methods and compositions for the repair of articular cartilage defects in mammals
CA2192103C (en) * 1994-06-06 2002-02-05 Arnold I. Caplan Biomatrix for tissue regeneration
US5837235A (en) * 1994-07-08 1998-11-17 Sulzer Medizinaltechnik Ag Process for regenerating bone and cartilage
SE9402528D0 (sv) * 1994-07-19 1994-07-19 Astra Ab Hårdvävnadsstimulerande med el
SE9402531L (sv) * 1994-07-19 1996-01-20 Medicarb Ab Sårläkningsmedel
US5510102A (en) * 1995-01-23 1996-04-23 The Regents Of The University Of California Plasma and polymer containing surgical hemostatic adhesives
US5749874A (en) * 1995-02-07 1998-05-12 Matrix Biotechnologies, Inc. Cartilage repair unit and method of assembling same
US6080194A (en) * 1995-02-10 2000-06-27 The Hospital For Joint Disease Orthopaedic Institute Multi-stage collagen-based template or implant for use in the repair of cartilage lesions
US5906934A (en) * 1995-03-14 1999-05-25 Morphogen Pharmaceuticals, Inc. Mesenchymal stem cells for cartilage repair
NL9500580A (nl) * 1995-03-27 1996-11-01 Hollandse Signaalapparaten Bv Phased array antenne voorzien van een calibratienetwerk.
US5620706A (en) 1995-04-10 1997-04-15 Universite De Sherbrooke Polyionic insoluble hydrogels comprising xanthan and chitosan
AU723740B2 (en) * 1995-06-06 2000-09-07 Howmedica Inc. Biocompatible hydroxyapatite formulations and uses therefor
US5655546A (en) * 1995-06-07 1997-08-12 Halpern; Alan A. Method for cartilage repair
JPH11507697A (ja) * 1995-06-09 1999-07-06 エヌ. ドロハン,ウィリアム キチンヒドロゲル、それらの製造方法及び利用
JP3881707B2 (ja) * 1995-07-20 2007-02-14 学校法人松本歯科大学 骨形成促進剤の製造方法及び骨形成促進剤を用いた骨形成組成物の製造方法
TW389694B (en) * 1995-08-17 2000-05-11 Novartis Ag Compositions including o-carboxyalkyl chitosan and methods of use in ophthalmics
US5944754A (en) * 1995-11-09 1999-08-31 University Of Massachusetts Tissue re-surfacing with hydrogel-cell compositions
JP3781433B2 (ja) * 1995-11-16 2006-05-31 ケース ウエスターン リザーブ ユニバーシティ ヒト間葉幹細胞の試験管内軟骨形成誘導
US6200606B1 (en) * 1996-01-16 2001-03-13 Depuy Orthopaedics, Inc. Isolation of precursor cells from hematopoietic and nonhematopoietic tissues and their use in vivo bone and cartilage regeneration
US5842477A (en) * 1996-02-21 1998-12-01 Advanced Tissue Sciences, Inc. Method for repairing cartilage
US6060534A (en) 1996-07-11 2000-05-09 Scimed Life Systems, Inc. Medical devices comprising ionically and non-ionically crosslinked polymer hydrogels having improved mechanical properties
US6649192B2 (en) 1996-07-29 2003-11-18 Universidade De Santiago De Compostela Application of nanoparticles based on hydrophilic polymers as pharmaceutical forms
US6706690B2 (en) 1999-06-10 2004-03-16 Baxter Healthcare Corporation Hemoactive compositions and methods for their manufacture and use
US7320962B2 (en) 1996-08-27 2008-01-22 Baxter International Inc. Hemoactive compositions and methods for their manufacture and use
US5866415A (en) * 1997-03-25 1999-02-02 Villeneuve; Peter E. Materials for healing cartilage and bone defects
CA2212300A1 (en) * 1997-08-04 1999-02-04 Abdellatif Chenite In vitro or in vivo gelfying chitosan and therapeutic uses thereof
US6110209A (en) * 1997-08-07 2000-08-29 Stone; Kevin R. Method and paste for articular cartilage transplantation
US6417247B1 (en) * 1997-10-14 2002-07-09 Beth L. Armstrong Polymer/ceramic composites
US6911212B2 (en) 1998-02-27 2005-06-28 Musculoskeletal Transplant Foundation Malleable putty and flowable paste with allograft bone having residual calcium for filling bone defects
US7019192B2 (en) 1998-02-27 2006-03-28 Musculoskeletal Transplant Foundation Composition for filling bone defects
US7045141B2 (en) 1998-02-27 2006-05-16 Musculoskeletal Transplant Foundation Allograft bone composition having a gelatin binder
US6179872B1 (en) * 1998-03-17 2001-01-30 Tissue Engineering Biopolymer matt for use in tissue repair and reconstruction
US20030147860A1 (en) 2002-02-07 2003-08-07 Marchosky J. Alexander Compositions and methods for forming and strengthening bone
WO2001000792A1 (en) * 1999-06-29 2001-01-04 Marchosky J Alexander Compositions and methods for forming and strengthening bone
US6350588B1 (en) 1999-07-20 2002-02-26 Micrology Laboratories, Llc Test media and quantitative or qualitative method for identification and differentiation of biological materials in a test sample
US6429013B1 (en) 1999-08-19 2002-08-06 Artecel Science, Inc. Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair
AU1375301A (en) 1999-11-15 2001-05-30 Bio Syntech Canada Inc Temperature-controlled and ph-dependant self-gelling biopolymeric aqueous solution
ATE243049T1 (de) 1999-12-09 2003-07-15 Biosyntech Canada Inc Mineral-polymer hybrid-zusammensetzung
US20030158302A1 (en) 1999-12-09 2003-08-21 Cyric Chaput Mineral-polymer hybrid composition
KR100880622B1 (ko) 2000-06-29 2009-01-30 바이오신텍 캐나다 인코포레이티드 연골 및 다른 조직의 복구 및 재생용 조성물 및 방법
AU2002221370A1 (en) 2000-11-15 2002-05-27 Bio Syntech Canada Inc Method for restoring a damaged or degenerated intervertebral disc
US20040047892A1 (en) 2000-11-15 2004-03-11 Desrosiers Eric Andre Filler composition for soft tissue augmentation and reconstructive surgery
US6756363B1 (en) 2000-11-17 2004-06-29 Wound Healing Of Oklahoma, Inc. Solutions and films of glycated chitosan
ATE312615T1 (de) 2001-08-14 2005-12-15 Medipost Co Ltd Zusammensetzung zur behandlung von schäden des gelenkknorpels
US8740973B2 (en) 2001-10-26 2014-06-03 Icon Medical Corp. Polymer biodegradable medical device
SI1455802T1 (sl) 2001-12-14 2009-06-30 Dnp Canada Inc Uporaba hitozanskih oligosaharidov
US7514249B2 (en) 2002-04-18 2009-04-07 The University Of Florida Research Foundation, Inc. Biomimetic organic/inorganic composites
US20060204544A1 (en) 2002-05-20 2006-09-14 Musculoskeletal Transplant Foundation Allograft bone composition having a gelatin binder
JP2006503004A (ja) 2002-07-31 2006-01-26 アルザ・コーポレーション 射出可能なデポ組成物及びその使用
DE60325742D1 (de) 2002-07-31 2009-02-26 Alza Corp Injizierbare multimodale polymere depotzusammensetzungen und ihre verwendungen
CA2500220A1 (en) 2002-09-30 2004-04-08 Regen Biotech, Inc. Composition for stimulating bone-formation and bone consolidation
ATE418323T1 (de) 2002-11-06 2009-01-15 Alza Corp Depot-formulierungen mit verzögerter freisetzung
GB0302738D0 (en) 2003-02-06 2003-03-12 Advanced Biopolymers As Composition
US7217294B2 (en) 2003-08-20 2007-05-15 Histogenics Corp. Acellular matrix implants for treatment of articular cartilage, bone or osteochondral defects and injuries and method for use thereof
GB0403938D0 (en) 2004-02-21 2004-03-24 West Pharm Serv Drug Res Ltd Chitosan containing solution
US20060062768A1 (en) 2004-09-23 2006-03-23 Olexander Hnojewyj Biocompatible hydrogel compositions
ITRM20040539A1 (it) 2004-11-02 2005-02-02 Mavi Sud S R L Preparati a base di chitina o suoi derivati per uso cosmetico o medico.
WO2007127795A2 (en) 2006-04-25 2007-11-08 Bumgardner Joel D Chitosan/nanocrystalline hydroxyapatite composite microsphere-based scaffolds
US20100178355A1 (en) 2006-11-30 2010-07-15 Hoemann Caroline D Method for in situ solidification of blood-polymer compositions for regenerative medicine and cartilage repair applications
US8153612B2 (en) 2006-12-11 2012-04-10 Chi2Gel Ltd. Injectable chitosan mixtures forming hydrogels
US7776840B2 (en) 2007-02-21 2010-08-17 Cutanea Life Sciences, Inc. Methods of use of biomaterial and injectable implant containing biomaterial

Also Published As

Publication number Publication date
AU1979201A (en) 2001-06-18
EP1255576B1 (de) 2003-08-20
AU1848601A (en) 2001-06-18
EP1237585B1 (de) 2003-06-18
DE60003459T2 (de) 2004-05-06
DE60004710D1 (de) 2003-09-25
DE60003459D1 (de) 2003-07-24
DE60004710T2 (de) 2004-07-08
WO2001041821A1 (en) 2001-06-14
US20030199615A1 (en) 2003-10-23
WO2001041822A1 (en) 2001-06-14
EP1255576A1 (de) 2002-11-13
US20100029549A1 (en) 2010-02-04
US8389467B2 (en) 2013-03-05
EP1237585A1 (de) 2002-09-11
ATE247495T1 (de) 2003-09-15

Similar Documents

Publication Publication Date Title
ATE247495T1 (de) Mineral-polymer hybrid-zusammensetzung
ATE328851T1 (de) Magnesium-ammonium-phosphat-zemente, deren herstellung und verwendung
DE69403439D1 (de) Tgf-beta zusammensetzung zum herbeiführen von knochenwachstum
AU2841099A (en) Method for preparing a biomaterial based on hydroxyapatite, resulting biomaterial and surgical or dental use
DE60135841D1 (de)
BR9712036A (pt) Composição de remineralização.
KR960702294A (ko) 인산칼슘 수산화인회석 전구체 및 그것의 제조방법 및 사용방법 (calcium phosphate hydroxyapatite precursor and methods for making and using the same)
DK0692986T3 (da) Biomaterialepræparat samt fremgangsmåde til fremstilling heraf
DE50309585D1 (de) Strontium-apatit-zement-zubereitungen und deren verwendungen
ATE249486T1 (de) Wässrige reaktive spachtelmassen (i)
DE60202461D1 (de) Kalziumphosphat / -sulfat-basierte knochenimplantat zusammensetzung
DE60129681D1 (de) Anreicherung von milch mit lebensmittelmineralien
PT1259271E (pt) Processo de preparação de um material pastoso injectável
ATE157329T1 (de) Innige mischung von galcium- und phosphat-quellen als hydroxyapatit-vorläufer
ATE332151T1 (de) Pulvergemisch für resorbierbare calciumphosphat- biozemente
ES8507349A1 (es) Una pasta para hemostasis y union temporal de defectos en casos de traumas de huesos
IL154007A0 (en) Soluble fertilizer compositions comprising calcium and/or magnesium phosphates
CA2176535A1 (en) Peat based compositions
EP1394132A3 (de) Neue Calciumphosphatzementzusammensetzung und ihr Herstellungsverfahren
AR019759A1 (es) Un cemento biologico
TR200101158T1 (tr) Yüzeyi modifiye edilmiş manganez sülfit, bunu üretme yöntemi ve kullanılması.
KR970001255A (ko) 고기능성 요업원료의 합성

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties