NO311006B1 - Farmasoytisk blanding av peptider med karboksy-avsluttede polyestere, fremgangsmate for fremstilling derav og mikropartikler - Google Patents

Farmasoytisk blanding av peptider med karboksy-avsluttede polyestere, fremgangsmate for fremstilling derav og mikropartikler Download PDF

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Publication number
NO311006B1
NO311006B1 NO19944535A NO944535A NO311006B1 NO 311006 B1 NO311006 B1 NO 311006B1 NO 19944535 A NO19944535 A NO 19944535A NO 944535 A NO944535 A NO 944535A NO 311006 B1 NO311006 B1 NO 311006B1
Authority
NO
Norway
Prior art keywords
peptide
polyester
salt
goserelin
drug
Prior art date
Application number
NO19944535A
Other languages
English (en)
Norwegian (no)
Other versions
NO944535D0 (no
NO944535L (no
Inventor
Francis Gowland Hutchinson
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of NO944535D0 publication Critical patent/NO944535D0/no
Publication of NO944535L publication Critical patent/NO944535L/no
Publication of NO311006B1 publication Critical patent/NO311006B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
    • A61K47/6927—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/593—Polyesters, e.g. PLGA or polylactide-co-glycolide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2989—Microcapsule with solid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Polyesters Or Polycarbonates (AREA)
NO19944535A 1992-05-28 1994-11-25 Farmasoytisk blanding av peptider med karboksy-avsluttede polyestere, fremgangsmate for fremstilling derav og mikropartikler NO311006B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB@@@@A GB9211268D0 (en) 1992-05-28 1992-05-28 Salts of basic peptides with carboxyterminated polyesters
PCT/GB1993/001079 WO1993024150A1 (en) 1992-05-28 1993-05-25 Salts of peptides with carboxy-terminated polyesters

Publications (3)

Publication Number Publication Date
NO944535D0 NO944535D0 (no) 1994-11-25
NO944535L NO944535L (no) 1995-01-25
NO311006B1 true NO311006B1 (no) 2001-10-01

Family

ID=10716132

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19944535A NO311006B1 (no) 1992-05-28 1994-11-25 Farmasoytisk blanding av peptider med karboksy-avsluttede polyestere, fremgangsmate for fremstilling derav og mikropartikler

Country Status (33)

Country Link
US (3) US5889110A (de)
JP (1) JPH08501064A (de)
KR (1) KR100293882B1 (de)
AT (1) AT407702B (de)
AU (1) AU682310B2 (de)
BE (1) BE1006143A3 (de)
CA (1) CA2136751C (de)
CH (2) CH688911A5 (de)
CZ (1) CZ292449B6 (de)
DE (2) DE4392401T1 (de)
DK (1) DK176134B1 (de)
ES (1) ES2107357B1 (de)
FI (1) FI112603B (de)
FR (1) FR2691631B1 (de)
GB (3) GB9211268D0 (de)
GR (1) GR1001550B (de)
HK (1) HK133097A (de)
HU (1) HUT70177A (de)
IE (1) IE74715B1 (de)
IL (1) IL105710A (de)
IT (1) IT1271139B (de)
LU (1) LU88559A1 (de)
MC (1) MC2330A1 (de)
NL (1) NL195056C (de)
NO (1) NO311006B1 (de)
NZ (1) NZ252268A (de)
RU (1) RU2152225C1 (de)
SE (1) SE501970C2 (de)
SG (1) SG44645A1 (de)
SK (1) SK280320B6 (de)
TW (1) TW223018B (de)
WO (1) WO1993024150A1 (de)
ZA (1) ZA933358B (de)

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SK143494A3 (en) 1995-07-11
IE74715B1 (en) 1997-07-30
US20020198315A1 (en) 2002-12-26
DK176134B1 (da) 2006-09-18
HUT70177A (en) 1995-09-28
AT407702B (de) 2001-05-25
ATA901993A (de) 2000-10-15
IL105710A (en) 2001-03-19
AU682310B2 (en) 1997-10-02
LU88559A1 (fr) 1995-04-05
NO944535D0 (no) 1994-11-25
NZ252268A (en) 1996-12-20
BE1006143A3 (fr) 1994-05-24
RU94046097A (ru) 1996-09-20
NL195056C (nl) 2003-07-01
SE501970C2 (sv) 1995-07-03
CA2136751A1 (en) 1993-12-09
ITMI931099A1 (it) 1994-11-27
AU4084793A (en) 1993-12-30
ES2107357A1 (es) 1997-11-16
FI945553A0 (fi) 1994-11-25
US5889110A (en) 1999-03-30
GB9309645D0 (en) 1993-06-23
FR2691631B1 (fr) 1995-06-09
DE4392401T1 (de) 1997-07-24
NL9320034A (nl) 1995-04-03
CZ293794A3 (en) 1995-03-15
IE930358A1 (en) 1993-12-01
HU9403371D0 (en) 1995-02-28
IL105710A0 (en) 1993-09-22
RU2152225C1 (ru) 2000-07-10
ZA933358B (en) 1994-09-15
GR1001550B (el) 1994-04-29
JPH08501064A (ja) 1996-02-06
DK135394A (da) 1994-11-28
FR2691631A1 (fr) 1993-12-03
US6034175A (en) 2000-03-07
NO944535L (no) 1995-01-25
HK133097A (en) 1997-10-24
WO1993024150A1 (en) 1993-12-09
GB9423366D0 (en) 1995-01-25
IT1271139B (it) 1997-05-27
SE9404115L (sv) 1994-11-28
GB2282066A (en) 1995-03-29
CH688911A5 (de) 1998-05-29
ITMI931099A0 (it) 1993-05-27
GB2282066B (en) 1996-11-06
FI945553L (fi) 1995-01-25
CH690491A5 (de) 2000-09-29
KR100293882B1 (ko) 2001-09-17
FI112603B (fi) 2003-12-31
SE9404115D0 (sv) 1994-11-28
ES2107357B1 (es) 1998-10-16
SK280320B6 (sk) 1999-11-08
MC2330A1 (fr) 1994-05-31
CZ292449B6 (cs) 2003-09-17
SG44645A1 (en) 1997-12-19
GB9211268D0 (en) 1992-07-15
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CA2136751C (en) 2006-10-31

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