NO313268B1 - Anvendelse av (2S,4S)-1-(2-hydroksymetyl-1,3-dioksolan-4- yl)cytosin for fremstilling av medikamenter for behandling avcancer - Google Patents

Anvendelse av (2S,4S)-1-(2-hydroksymetyl-1,3-dioksolan-4- yl)cytosin for fremstilling av medikamenter for behandling avcancer Download PDF

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Publication number
NO313268B1
NO313268B1 NO19971015A NO971015A NO313268B1 NO 313268 B1 NO313268 B1 NO 313268B1 NO 19971015 A NO19971015 A NO 19971015A NO 971015 A NO971015 A NO 971015A NO 313268 B1 NO313268 B1 NO 313268B1
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NO
Norway
Prior art keywords
cancer
oddc
compound
treatment
cells
Prior art date
Application number
NO19971015A
Other languages
English (en)
Norwegian (no)
Other versions
NO971015D0 (no
NO971015L (no
Inventor
Chung K Chu
Yung-Chi Cheng
Original Assignee
Univ Yale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/301,298 external-priority patent/US5817667A/en
Application filed by Univ Yale filed Critical Univ Yale
Publication of NO971015D0 publication Critical patent/NO971015D0/no
Publication of NO971015L publication Critical patent/NO971015L/no
Publication of NO313268B1 publication Critical patent/NO313268B1/no

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
NO19971015A 1994-09-06 1997-03-05 Anvendelse av (2S,4S)-1-(2-hydroksymetyl-1,3-dioksolan-4- yl)cytosin for fremstilling av medikamenter for behandling avcancer NO313268B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/301,298 US5817667A (en) 1991-04-17 1994-09-06 Compounds and methods for the treatment of cancer
US39063395A 1995-02-17 1995-02-17
PCT/US1995/011464 WO1996007413A1 (en) 1994-09-06 1995-09-05 Compounds and methods for the treatment of cancer

Publications (3)

Publication Number Publication Date
NO971015D0 NO971015D0 (no) 1997-03-05
NO971015L NO971015L (no) 1997-03-05
NO313268B1 true NO313268B1 (no) 2002-09-09

Family

ID=26972285

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19971015A NO313268B1 (no) 1994-09-06 1997-03-05 Anvendelse av (2S,4S)-1-(2-hydroksymetyl-1,3-dioksolan-4- yl)cytosin for fremstilling av medikamenter for behandling avcancer

Country Status (31)

Country Link
US (3) US6063787A (de)
EP (2) EP1468687A1 (de)
JP (1) JP3979662B2 (de)
KR (1) KR100374477B1 (de)
CN (3) CN1827108A (de)
AP (1) AP783A (de)
AT (1) ATE267015T1 (de)
AU (1) AU704977B2 (de)
BG (1) BG63122B1 (de)
BR (1) BR9508886A (de)
CA (1) CA2199117C (de)
CZ (1) CZ297873B6 (de)
DE (1) DE69533066T2 (de)
DK (1) DK0781136T3 (de)
ES (1) ES2219666T3 (de)
FI (1) FI970918A7 (de)
HU (1) HUT77172A (de)
IL (1) IL115156A (de)
IS (1) IS2011B (de)
MY (1) MY121548A (de)
NO (1) NO313268B1 (de)
NZ (1) NZ335013A (de)
OA (1) OA10473A (de)
PL (2) PL189288B1 (de)
PT (1) PT781136E (de)
RO (1) RO118748B1 (de)
RU (1) RU2168995C2 (de)
SI (1) SI0781136T1 (de)
SK (1) SK284564B6 (de)
WO (1) WO1996007413A1 (de)
ZA (1) ZA957483B (de)

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Also Published As

Publication number Publication date
JP3979662B2 (ja) 2007-09-19
ES2219666T3 (es) 2004-12-01
BG63122B1 (bg) 2001-04-30
IL115156A (en) 2000-07-16
EP0781136A1 (de) 1997-07-02
NO971015D0 (no) 1997-03-05
AU704977B2 (en) 1999-05-13
DK0781136T3 (da) 2004-08-02
FI970918A0 (fi) 1997-03-04
OA10473A (en) 2002-04-08
MY121548A (en) 2006-02-28
ZA957483B (en) 1997-06-06
US20050261320A1 (en) 2005-11-24
CA2199117C (en) 2006-04-11
KR970705393A (ko) 1997-10-09
HUT77172A (hu) 1998-03-02
IL115156A0 (en) 1995-12-31
US6063787A (en) 2000-05-16
JPH10506385A (ja) 1998-06-23
IS2011B (is) 2005-05-13
CZ297873B6 (cs) 2007-04-18
IS4434A (is) 1997-03-04
SK28197A3 (en) 1997-09-10
US8076347B2 (en) 2011-12-13
AP9700939A0 (en) 1997-04-30
FI970918L (fi) 1997-05-02
EP0781136A4 (de) 1999-06-23
WO1996007413A1 (en) 1996-03-14
PT781136E (pt) 2004-09-30
PL188359B1 (pl) 2005-01-31
BR9508886A (pt) 1997-12-30
NZ335013A (en) 2000-07-28
RU2168995C2 (ru) 2001-06-20
CN1827108A (zh) 2006-09-06
CN1111409C (zh) 2003-06-18
DE69533066T2 (de) 2005-06-02
US20080171758A1 (en) 2008-07-17
CZ63397A3 (en) 1997-07-16
EP1468687A1 (de) 2004-10-20
EP0781136B1 (de) 2004-05-19
SI0781136T1 (en) 2004-08-31
CN1251680C (zh) 2006-04-19
CN1448142A (zh) 2003-10-15
FI970918A7 (fi) 1997-05-02
AU3586295A (en) 1996-03-27
US7262213B2 (en) 2007-08-28
NO971015L (no) 1997-03-05
CA2199117A1 (en) 1996-03-14
PL318971A1 (en) 1997-07-21
ATE267015T1 (de) 2004-06-15
BG101284A (bg) 1998-03-31
KR100374477B1 (ko) 2003-06-19
DE69533066D1 (de) 2004-06-24
CN1160351A (zh) 1997-09-24
SK284564B6 (sk) 2005-06-02
RO118748B1 (ro) 2003-10-30
AP783A (en) 1999-11-17
PL189288B1 (pl) 2005-07-29

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