NO314127B1 - Injiserbare NMR-billeddannende sammensetninger, fremgangsmåter for fremstilling og anvendelse av disse - Google Patents

Injiserbare NMR-billeddannende sammensetninger, fremgangsmåter for fremstilling og anvendelse av disse Download PDF

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Publication number
NO314127B1
NO314127B1 NO19970665A NO970665A NO314127B1 NO 314127 B1 NO314127 B1 NO 314127B1 NO 19970665 A NO19970665 A NO 19970665A NO 970665 A NO970665 A NO 970665A NO 314127 B1 NO314127 B1 NO 314127B1
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NO
Norway
Prior art keywords
composition according
acid
imaging
surfactant
physiologically acceptable
Prior art date
Application number
NO19970665A
Other languages
English (en)
Norwegian (no)
Other versions
NO970665L (no
NO970665D0 (no
Inventor
Herve Tournier
Bernard Lamy
Roland Hyacinthe
Original Assignee
Bracco Research Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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Application filed by Bracco Research Sa filed Critical Bracco Research Sa
Publication of NO970665D0 publication Critical patent/NO970665D0/no
Publication of NO970665L publication Critical patent/NO970665L/no
Publication of NO314127B1 publication Critical patent/NO314127B1/no

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
NO19970665A 1995-06-15 1997-02-13 Injiserbare NMR-billeddannende sammensetninger, fremgangsmåter for fremstilling og anvendelse av disse NO314127B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP95810403 1995-06-15
PCT/IB1996/000577 WO1997000087A1 (en) 1995-06-15 1996-06-14 Blood-pool imaging compositions use and method

Publications (3)

Publication Number Publication Date
NO970665D0 NO970665D0 (no) 1997-02-13
NO970665L NO970665L (no) 1997-04-03
NO314127B1 true NO314127B1 (no) 2003-02-03

Family

ID=8221760

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19970665A NO314127B1 (no) 1995-06-15 1997-02-13 Injiserbare NMR-billeddannende sammensetninger, fremgangsmåter for fremstilling og anvendelse av disse

Country Status (13)

Country Link
US (1) US5833948A (de)
EP (1) EP0804251B1 (de)
JP (1) JP4335976B2 (de)
KR (1) KR100399712B1 (de)
AT (1) ATE224737T1 (de)
AU (1) AU708328B2 (de)
CA (1) CA2195633C (de)
DE (1) DE69623929T2 (de)
ES (1) ES2180784T3 (de)
NO (1) NO314127B1 (de)
PT (1) PT804251E (de)
WO (1) WO1997000087A1 (de)
ZA (1) ZA965101B (de)

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IT1297035B1 (it) * 1997-12-30 1999-08-03 Bracco Spa Derivati dell'acido 1,4,7,10-tetraazaciclododecan-1,4-diacetico
IT1297034B1 (it) * 1997-12-30 1999-08-03 Bracco Spa Acido 1,4,7,10-tetraazaciclododecan-1,4-diacetico
US6342598B1 (en) 1998-11-26 2002-01-29 Bracco International B.V. Amphipatic polycarboxylic chelates and complexes with paramagnetic metals as MRI contrast agents
IT1304501B1 (it) * 1998-12-23 2001-03-19 Bracco Spa Uso di derivati di acidi biliari coniugati con complessi metallicicome "blood pool agents" per l'indagine diagnostica tramite risonanza
US7109167B2 (en) 2000-06-02 2006-09-19 Bracco International B.V. Compounds for targeting endothelial cells, compositions containing the same and methods for their use
US6984395B2 (en) * 2001-04-11 2006-01-10 Qlt, Inc. Drug delivery system for hydrophobic drugs
US20060073197A1 (en) * 2004-05-20 2006-04-06 Ramaekers Joseph C Encapsulated transfer factor compositions and methods of use
US20070128253A1 (en) * 2005-04-13 2007-06-07 Ramaekers Joseph C Encapsulated transfer factor compositions and methods of use
US6506413B1 (en) * 2001-04-30 2003-01-14 Joseph C. Ramaekers Compositions for treating animal diseases and syndromes
US6803046B2 (en) * 2002-08-16 2004-10-12 Bracco International B.V. Sincalide formulations
US20050130892A1 (en) * 2003-03-07 2005-06-16 Xencor, Inc. BAFF variants and methods thereof
US20060014248A1 (en) * 2003-01-06 2006-01-19 Xencor, Inc. TNF super family members with altered immunogenicity
US7553930B2 (en) * 2003-01-06 2009-06-30 Xencor, Inc. BAFF variants and methods thereof
US20050221443A1 (en) * 2003-01-06 2005-10-06 Xencor, Inc. Tumor necrosis factor super family agonists
DE602004029010D1 (de) 2003-02-04 2010-10-21 Bracco Suisse Sa Ultraschall kontrastmittel und verfahren zur erstellung
EP1675871A2 (de) 2003-10-10 2006-07-05 Xencor Inc. Tnf-alpha-varianten auf proteinbasis zur behandlung von erkrankungen in verbindung mit tnf-alpha
CA2547024C (en) 2003-12-22 2013-12-17 Bracco Research Sa Gas-filled microvesicle assembly for contrast imaging
US20050152842A1 (en) * 2003-12-24 2005-07-14 Chun Li Poly (L-glutamic acid) paramagnetic material complex and use as a biodegradable MRI contrast agent
DE602005010424D1 (de) * 2004-06-03 2008-11-27 Bracco Research Sa Liposomale anordnung für die therapeutische und/oder diagnostische anwendung
JP4837663B2 (ja) 2004-08-18 2011-12-14 ブラッコ・シュイス・ソシエテ・アノニム 造影画像化のためのガス充填微小胞組成物
FR2883562B1 (fr) 2005-03-24 2009-02-27 Guerbet Sa Chelates lipophiles et leur utilisation en imagerie
CA2603437A1 (en) * 2005-04-01 2006-10-12 The Board Of Regents Of The University Of Texas System Poly(peptide) as a chelator: methods of manufacture and uses
WO2006128643A2 (en) * 2005-05-31 2006-12-07 Inbios S.R.L. Supramolecular aggregates containing chelating agents and bioactive peptides as effective and selective delivery tools for drugs and contrast agents in mri or nuclear medicine
US20090053197A1 (en) * 2006-06-14 2009-02-26 Ramaekers Joseph C Transfer Factor Compositions and Methods
US9125874B2 (en) 2007-11-30 2015-09-08 The Ramaekers Family Trust Administration of transfer factor for improving reproductive health
DE602007006968D1 (de) 2006-09-05 2010-07-15 Bracco Research Sa Gasgefüllte mikrovesikel mit polymer-modifizierten lipiden
GB0623838D0 (en) * 2006-11-29 2007-01-10 Malvern Cosmeceutics Ltd Novel compositions
US20090074751A1 (en) * 2007-09-18 2009-03-19 Ramaekers Nutrition, Inc. Growth factor fraction compositions and methods
KR101401217B1 (ko) * 2007-11-07 2014-05-28 충남대학교산학협력단 Ｐｅ－ｄｔｐａ의 새로운 용도
MX2010005317A (es) 2007-11-20 2010-06-02 Ambrx Inc Polipeptidos de insulina modificados y sus usos.
EP2278984A4 (de) * 2007-11-30 2013-02-27 Ramaekers Family Trust Zusammensetzungen und verfahren zur verbesserung der fertilität
SG10201500237TA (en) 2008-01-30 2015-04-29 Histogen Inc Extracellular matrix compositions
WO2010094043A2 (en) 2009-02-13 2010-08-19 University Of Washington Gadolinium expressed lipid nanoparticles for magnetic resonance imaging
WO2010139003A1 (en) * 2009-06-01 2010-12-09 Commonwealth Scientific And Industrial Research Organisation Chelating amphiphiles
EA030886B1 (ru) 2010-08-17 2018-10-31 Амбркс, Инк. Модифицированные полипептиды релаксина, содержащие некодируемую в природе аминокислоту, связанную с полимером, и их применение
EP2639227A1 (de) 2012-03-14 2013-09-18 Bracco Imaging S.p.A Neue Klasse von Diazepinderivatchelatbildnern und Komplexe mit paramagnetischen Metallen als MRI-Kontrastmittel
EP2892570B1 (de) 2012-09-07 2019-02-27 Bracco Imaging S.p.A Paramagnetische feste lipidnanopartikel zur kernspinnresonanzbildgebung, die amphiphile metallkomplexe enthalten
EP3738605A1 (de) 2012-09-10 2020-11-18 Xencor, Inc. Verfahren zur behandlung von neurologischen erkrankungen
EP2934740B1 (de) 2012-12-21 2019-12-11 Bracco Suisse SA Gasgefüllte mikrovesikel
WO2015119642A1 (en) 2014-02-10 2015-08-13 The Johns Hopkins University Low oxygen tension enhances endothelial fate of human pluripotent stem cells
US10519207B2 (en) 2015-06-12 2019-12-31 Georgia State University Research Foundation, Inc. Compositions and methods for treating opioid tolerance
US11110063B2 (en) 2017-08-25 2021-09-07 MAIA Pharmaceuticals, Inc. Storage stable sincalide formulations
US12077780B2 (en) 2020-02-14 2024-09-03 Allergan Sales, Llc Conditioned medium from cells cultured under hypoxic conditions and uses thereof

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US5387410A (en) * 1983-03-18 1995-02-07 Mallinckrodt, Inc. Method for enhancing magnetic resonance with compositions containing paramagnetic elements carried by liposomes
US4728575A (en) * 1984-04-27 1988-03-01 Vestar, Inc. Contrast agents for NMR imaging
US5215680A (en) * 1990-07-10 1993-06-01 Cavitation-Control Technology, Inc. Method for the production of medical-grade lipid-coated microbubbles, paramagnetic labeling of such microbubbles and therapeutic uses of microbubbles
CA2102605A1 (en) * 1991-05-23 1992-11-24 Evan C. Unger Liposoluble compounds for magnetic resonance imaging
US5464696A (en) * 1992-08-13 1995-11-07 Bracco International B.V. Particles for NMR imaging
US5534241A (en) * 1993-07-23 1996-07-09 Torchilin; Vladimir P. Amphipathic polychelating compounds and methods of use
US5567410A (en) * 1994-06-24 1996-10-22 The General Hospital Corporation Composotions and methods for radiographic imaging

Also Published As

Publication number Publication date
CA2195633A1 (en) 1997-01-03
EP0804251A1 (de) 1997-11-05
DE69623929T2 (de) 2003-05-15
WO1997000087A1 (en) 1997-01-03
DE69623929D1 (de) 2002-10-31
ES2180784T3 (es) 2003-02-16
JPH10504044A (ja) 1998-04-14
ATE224737T1 (de) 2002-10-15
JP4335976B2 (ja) 2009-09-30
KR100399712B1 (ko) 2004-02-18
CA2195633C (en) 2008-09-16
KR970704477A (ko) 1997-09-06
NO970665L (no) 1997-04-03
ZA965101B (en) 1997-01-22
PT804251E (pt) 2003-01-31
US5833948A (en) 1998-11-10
AU5843196A (en) 1997-01-15
AU708328B2 (en) 1999-08-05
NO970665D0 (no) 1997-02-13
EP0804251B1 (de) 2002-09-25

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Legal Events

Date Code Title Description
CB Opposition filed (par. 26,5 patents act)

Opponent name: AMERSHAM HEALTH AS, POSTBOKS 4220 NYDALEN, 0401 OS

Effective date: 20031104

ERR Erratum

Free format text: I PATENTTIDENDE NR 47 BLE INNSIGELSE I PATENT NR 314127 KUNNGJORT MED FEIL INNSIGELSESDAG.

MM1K Lapsed by not paying the annual fees