NO315517B1 - Polypeptid som er i stand til a gjenkjenne og selektivt binde humant FSH, DNA som koder for dette, rekombinant ekspresjonsvektor inneholdende dette DNA, celle transfektert med ekspresjonsvektoren, fremgangsmate for fremstilling av polypeptidet, farmasoyti - Google Patents
Polypeptid som er i stand til a gjenkjenne og selektivt binde humant FSH, DNA som koder for dette, rekombinant ekspresjonsvektor inneholdende dette DNA, celle transfektert med ekspresjonsvektoren, fremgangsmate for fremstilling av polypeptidet, farmasoyti Download PDFInfo
- Publication number
- NO315517B1 NO315517B1 NO19933272A NO933272A NO315517B1 NO 315517 B1 NO315517 B1 NO 315517B1 NO 19933272 A NO19933272 A NO 19933272A NO 933272 A NO933272 A NO 933272A NO 315517 B1 NO315517 B1 NO 315517B1
- Authority
- NO
- Norway
- Prior art keywords
- fsh
- receptor
- polypeptide
- fragment
- mutant
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Endocrinology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67008591A | 1991-03-15 | 1991-03-15 | |
| PCT/US1992/000122 WO1992016620A1 (fr) | 1991-03-15 | 1992-01-02 | Recepteur de l'hormone folliculostimulante humaine |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO933272D0 NO933272D0 (no) | 1993-09-14 |
| NO933272L NO933272L (no) | 1993-09-14 |
| NO315517B1 true NO315517B1 (no) | 2003-09-15 |
Family
ID=24688922
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19933272A NO315517B1 (no) | 1991-03-15 | 1993-09-14 | Polypeptid som er i stand til a gjenkjenne og selektivt binde humant FSH, DNA som koder for dette, rekombinant ekspresjonsvektor inneholdende dette DNA, celle transfektert med ekspresjonsvektoren, fremgangsmate for fremstilling av polypeptidet, farmasoyti |
Country Status (19)
| Country | Link |
|---|---|
| US (3) | US6121016A (fr) |
| EP (2) | EP0575357B1 (fr) |
| JP (1) | JP3581148B2 (fr) |
| KR (1) | KR100245250B1 (fr) |
| AT (2) | ATE224446T1 (fr) |
| AU (1) | AU671417B2 (fr) |
| CA (1) | CA2106061C (fr) |
| DE (2) | DE69232779T2 (fr) |
| DK (1) | DK0575357T3 (fr) |
| ES (1) | ES2183806T3 (fr) |
| FI (1) | FI109360B (fr) |
| GE (1) | GEP19991604B (fr) |
| LT (1) | LT3973B (fr) |
| LV (1) | LV10724B (fr) |
| MX (1) | MX9203350A (fr) |
| NO (1) | NO315517B1 (fr) |
| RU (1) | RU2193599C2 (fr) |
| UA (1) | UA43826C2 (fr) |
| WO (1) | WO1992016620A1 (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU3949893A (en) * | 1992-03-30 | 1993-11-08 | Akzo Nobel N.V. | Human gonadotropin receptor (FSH receptor) |
| SI0894141T1 (en) | 1996-02-20 | 2005-10-31 | Applied Research Systems Ars Holding N.V. | Hybrid proteins which form heterodimers |
| US5925549A (en) * | 1996-04-15 | 1999-07-20 | The Board Of Trustees Of The Leland Stanford Junior University | Soluble 7-transmembrane domain G-protein-coupled receptor compositions and methods |
| US6521641B1 (en) | 1998-10-08 | 2003-02-18 | Allergan, Inc. | Male anti-fertility agents |
| AU5137900A (en) * | 1999-05-28 | 2000-12-18 | University Of Cincinnati, The | Antisense oligonucleotides for fertility and menstrual cycle regulation and for chemopreventive and chemotherapeutic use |
| EP1287135A2 (fr) * | 2000-05-18 | 2003-03-05 | Bayer Aktiengesellschaft | Regulation du recepteur couple a la proteine geanalogue g l'hormone folliculo-stimulante humaine |
| WO2003062396A2 (fr) * | 2002-01-23 | 2003-07-31 | Arena Pharmaceuticals, Inc. | Versions non endogenes de recepteur humain fshr couples aux proteines g |
| EP1466620A1 (fr) * | 2003-04-11 | 2004-10-13 | AXXAM S.r.l. | Compositions permettant de moduler le récepteur de l'hormone folliculostimulante et ses applications thérapeutiques |
| US20100061976A1 (en) * | 2008-07-24 | 2010-03-11 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Method for treating or preventing osteoporosis by reducing follicle stimulating hormone to cyclic physiological levels in a mammalian subject |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4652450A (en) | 1984-08-31 | 1987-03-24 | Research Corporation | Bacterial FSH binding inhibitor |
| US4761371A (en) | 1985-02-12 | 1988-08-02 | Genentech, Inc. | Insulin receptor |
| US4859609A (en) * | 1986-04-30 | 1989-08-22 | Genentech, Inc. | Novel receptors for efficient determination of ligands and their antagonists or agonists |
| US4921808A (en) * | 1986-06-25 | 1990-05-01 | The Albany Medical College Of Union University | Method for determining follicle stimulating hormone |
| US4960700A (en) * | 1986-12-24 | 1990-10-02 | Genentech, Inc. | Compositions and methods for the synthesis and assay of a mammalian enkephalinase |
| EP1199361A3 (fr) * | 1989-05-05 | 2004-03-10 | Genentech Inc. | Molécules réceptrices des hormones glycoprotéiques. Leurs utilisations |
| US5155218A (en) * | 1990-05-08 | 1992-10-13 | Neurogenetic Corporation | Dna encoding human 5-ht1d receptors |
-
1992
- 1992-01-02 DE DE69232779T patent/DE69232779T2/de not_active Expired - Lifetime
- 1992-01-02 AT AT92904833T patent/ATE224446T1/de not_active IP Right Cessation
- 1992-01-02 RU RU93057956/13A patent/RU2193599C2/ru active
- 1992-01-02 DK DK92904833T patent/DK0575357T3/da active
- 1992-01-02 DE DE69233805T patent/DE69233805D1/de not_active Expired - Lifetime
- 1992-01-02 GE GEAP19921579A patent/GEP19991604B/en unknown
- 1992-01-02 EP EP92904833A patent/EP0575357B1/fr not_active Expired - Lifetime
- 1992-01-02 AU AU12514/92A patent/AU671417B2/en not_active Expired
- 1992-01-02 CA CA002106061A patent/CA2106061C/fr not_active Expired - Lifetime
- 1992-01-02 JP JP50530292A patent/JP3581148B2/ja not_active Expired - Lifetime
- 1992-01-02 ES ES92904833T patent/ES2183806T3/es not_active Expired - Lifetime
- 1992-01-02 WO PCT/US1992/000122 patent/WO1992016620A1/fr not_active Ceased
- 1992-01-02 AT AT01202809T patent/ATE505486T1/de not_active IP Right Cessation
- 1992-01-02 EP EP01202809A patent/EP1167385B1/fr not_active Expired - Lifetime
- 1992-02-01 UA UA93004376A patent/UA43826C2/uk unknown
- 1992-06-25 MX MX9203350A patent/MX9203350A/es unknown
-
1993
- 1993-09-14 NO NO19933272A patent/NO315517B1/no not_active IP Right Cessation
- 1993-09-14 FI FI934023A patent/FI109360B/fi active
- 1993-09-15 KR KR1019930702771A patent/KR100245250B1/ko not_active Expired - Lifetime
- 1993-10-11 LV LVP-93-1136A patent/LV10724B/en unknown
- 1993-12-20 LT LTIP1631A patent/LT3973B/lt not_active IP Right Cessation
-
1995
- 1995-06-07 US US08/482,855 patent/US6121016A/en not_active Expired - Lifetime
- 1995-06-07 US US08/474,986 patent/US6372711B1/en not_active Expired - Lifetime
- 1995-06-07 US US08/487,886 patent/US5744448A/en not_active Expired - Lifetime
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US6261800B1 (en) | Luteinizing hormone/choriogonadotropin (LH/CG) receptor | |
| EP0758898A1 (fr) | Antagonistes de l'activine utilises comme nouveaux contraceptifs | |
| US20210054041A1 (en) | Glycoprotein Hormone Long-Acting Superagonists | |
| NO315517B1 (no) | Polypeptid som er i stand til a gjenkjenne og selektivt binde humant FSH, DNA som koder for dette, rekombinant ekspresjonsvektor inneholdende dette DNA, celle transfektert med ekspresjonsvektoren, fremgangsmate for fremstilling av polypeptidet, farmasoyti | |
| EP0614975B1 (fr) | Molécules réceptrices d'hormone de glycoprotéine | |
| EP3065766A1 (fr) | Superagonistes a longue duree d'action a base d'hormone glycoproteique | |
| KR20040039320A (ko) | 인간호르몬의 비키메라 유사체를 제조하는 방법 | |
| US10457713B2 (en) | Glycoprotein hormone long-acting superagonists | |
| US20050042205A1 (en) | Glycoprotein hormone receptor molecules | |
| KR20000010866A (ko) | 당단백질 호르몬 초활성 효능약 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CREP | Change of representative |
Representative=s name: ONSAGERS AS, POSTBOKS 6963 ST OLAVS PLASS, 0130 OS |
|
| CREP | Change of representative |
Representative=s name: ZACCO NORWAY AS, POSTBOKS 2003 VIKA, 0125 OSLO, NO |
|
| MK1K | Patent expired |